The regional variation of seismicity along the northern Honshu arc, Japan, is studied using accurate focal depths and focal mechanism types. We use focal depths determined from pP‐P time intervals reported in the ISC bulletins. For submarine earthquakes, depths are corrected by considering the pP phase reported in the bulletins as the pwP phase (the reflection from the ocean surface). Out of more than 600 well‐located earthquakes selected from the ISC bulletins, we determine the types of the focal mechanisms of 184 events using P wave first motion data. Based on historical seismicity of great and large earthquakes, we divide the zone of thrust type earthquakes at the plate interface into two regions: the shallow thrust zone (0–40km), where great earthquakes (MS∼8.0) occur, and the deep thrust zone (40–60km), where large earthquakes (MS∼7.4) occur. The activity of great or large earthquakes shows a variation along the arc; in some regions, both the shallow and deep thrust zones are active, and in other regions, only one of the thrust zones is active. The seismicity of recent moderate size earthquakes (mb>4) combined with the focal mechanism type shows a variation along the arc, which reflects the variation of the activity of great or large earthquakes. Where large earthquakes do not occur in the deep thrust zone, neither thrust type nor down‐dip compression/tension type events occur in and beneath the deep thrust zone. Where large earthquakes do occur in the deep thrust zone, we find a number of thrust type earthquakes. Further, in the latter case, in some regions, the down‐dip compression and tension type events of the double seismic zones extend seaward just beneath the deep thrust zone and form a triple‐planed structure of seismicity (the triple seismic zone). This study confirms the hypothesis of previous workers (Seno and Pongsawat, 1981) on the causal relation between the strong seismic coupling of two converging plates at the deep thrust zone and extension of the double seismic zone; i.e., the presence or absence of activity within the slab beneath the deep seismic zone occurs when the deep thrust zone has a strong or weak coupling, respectively. Here, the weak coupling could be interpreted as either aseismic slip or as low stress buildup since the last large event occurred at the deep thrust zone. Triple seismic zones are found offshore of Miyagi prefecture, where the deep thrust zone has been broken recently in 1978, and offshore of Fukushima prefecture. We expect a future large earthquake at the deep thrust zone offshore of Fukushima prefecture because the presence of the triple seismic zone suggests stress has been accumulating and 40 years have passed since the deep thrust zone was ruptured in 1938.