De Pernambuco Research Articles

The snakes of the flooded region of Itaparica hydroeletric dam, Northeastern Brazil: “development” based on the drowning of wildlife

The previously underestimated biodiversity of the Caatinga underwent a transformation with the emergence of new studies, intensifying interest in the biota of this complex dry forest. Studies on snakes from the Caatinga have increased recently, resulting in 112 recorded species. Contributing to this, we present a detailed list of 23 species rescued from the Itaparica reservoir implementation in the 1980s. Collected specimens are deposited in the Herpetological and Paleoherpetological Collection at the Universidade Federal Rural de Pernambuco. The recorded snake assemblage is typical of the dry Caatingas of the Sertaneja Depression. We discuss the impacts of flooding and specimen relocation without adequate planning or monitoring on snake diversity. Finally, we conclude by questioning the sustainability aspects of development and interventions in nature.

Aspergillus capibaribensis (Eurotiales, Trichocomaceae), a new species in section Cremei

In this study we describe a new species of Aspergillus in section Cremei deposited in the URM culture collection (Micoteca URM Profa. Maria Auxiliadora Cavalcanti) of the Departamento de Micologia, Universidade Federal de Pernambuco (Recife, Pernambuco, Brazil). Another strain was obtained from samples taken from pollen pots inside nests of Melipona scutellaris (stingless bee). Morphological and phylogenetic evidence based on sequencing of ITS rDNA, BenA, CaM and rpb2 markers supported the description of taxonomic novelty. Aspergillus capibaribensis sp. nov. is morphologically similar and phylogenetically close to A. flaschentraegeri - the distinctive features are uniseriate and hyaline conidiophores, short and smooth conidia and smaller vesicles compared to the micromorphological structures of A. flaschentraegeri. This record also expanded the knowledge of species in Aspergillus section Cremei in a tropical country such as Brazil.

The Emergence of New Sporothrix brasiliensis Genotypes in Current Epidemic of Sporotrichosis in Southeastern Brazil.

Zoonotic sporotrichosis caused by Sporothrix brasiliensis has become the main subcutaneous mycosis in Brazil. Minas Gerais (MG) is located in southeast Brazil and since 2015 has experienced an epidemic of zoonotic sporotrichosis. This study aimed to reconstruct the epidemiological scenario of sporotrichosis from S. brasiliensis in recent epizooty in the Metropolitan Region of Belo Horizonte (MRBH), MG. A total of 95 Sporothrix spp. isolates (Sporothirx brasiliensis n = 74, S. schenckii n = 11 and S. globosa n = 10) were subjected to Amplified Fragment Length Polymorphism (AFLP) genotyping and mating-type analysis to determine genetic diversity and population structure. Of these, 46 S. brasiliensis isolates were recovered from animals (cats n = 41 and dogs n = 5) from MRBH. Our study describes the high interspecific differentiation power of AFLP-based genotyping between the main phylogenetic Sporothrix groups. S. brasiliensis presents high genetic variability and pronounced population structure with geographically focused outbreaks in Brazil. The genetic groups include older genotypes from the prolonged epidemic in Southeast (Rio de Janeiro and São Paulo), South (Rio Grande do Sul), Northeast (Pernambuco) and new genotypes from the MRBH. Furthermore, we provide evidence of heterothallism mating strategy in pathogenic Sporothrix species. Genotypes originating in Rio de Janeiro and Pernambuco carry the predominant MAT1-2 idiomorph as opposed to genotypes from Rio Grande do Sul, which have the MAT1-1 idiomorph. We observed an overwhelming occurrence of MAT1-1 among MRBH isolates. Our study provides clear evidence of the predominance of a genetic group profile circulating in animals in Minas Gerais, independent of that disseminated from Rio de Janeiro. Our data can help us understand the genetic population processes that drive the evolution of this fungus in Minas Gerais and contribute to future mitigation actions for this ongoing epidemic.

Expression of CD44highCD24Low cells, SOX2, and STAT3 transcription factors on peripheral blood and tumor tissue of penile squamous cell carcinoma.

Penile cancer is high in some underdeveloped countries. Signal transducer and activator of transcription 3 (STAT3) and CD44, CD24, and SOX2+ are known to be markers of diagnosis and prognosis in other cancers, but without studies in penile cancer. A cross-sectional study was conducted at the Hospital de Cancer de Pernambuco from March 2015 to December 2017. We performed SOX2, STAT3, CD24, and CD44 analyses in blood and tumor tissue by flow cytometry. High levels of CD44highCD24low, CD44highCD24lowpSTAT3+ and CD44hig hCD24low in the blood of patients compared to the controls (p < 0.05). Low of SOX2+ T cells in blood of patients compared to controls. High CD44highCD24low levels in patients with perineural invasion (PNI), tumor size > 3 cm, and pT2 stage (p < 0.05). High T cell levels in the blood and tumor tissue of patients with tumor ≤3 cm (p < 0.05). Increased SOX2+ T cells in blood of patients with PNI (-) and pT1 stage (p < 0.05). CD44highCD24lowpSTAT3+ (r = 0.669; p = 0.024) and SOX2+T cells (r = 0.404, p = 0.029) correlation were observed between blood and tumor tissue in penile cancer patients. CD44, CD24, and SOX2 molecules were markers of advanced disease associated with the worst prognosis in CaPe. However, pSTAT3 and T cells were associated with a more favorable prognosis in this study.

Analysis of the expression of cytokines and chemokines, platelet-leukocyte aggregates, sCD40L and sCD62P in cutaneous melanoma.

Cutaneous melanoma (CM) is a malignancy with a variable incidence worldwide and a poor advanced-stage prognosis. Melanoma growth is closely associated with the immune system. A cross-sectional study was performed on CM patients admitted at the Hospital de Cancer de Pernambuco (HCP) between 2015 and 2018. Fifty-one CM patients were included, and 30 healthy individuals. The study aimed to evaluate the association of platelet activation mechanisms and inflammatory response in patients with cutaneous melanoma. Elevated serum IL10 and low serum TNF levels in CM patients compared to controls (p < 0.05). High IL6 levels in patients with negative lymph nodes LN (-) compared to positive lymph nodes group (LN +, p = 0.0005). Low RANTES levels in patients compared to controls (p < 0.05). Elevated levels of platelet-lymphocyte (PLA), platelet-monocytes (PMA), and platelet-neutrophils (PNA) aggregates were observed in patients compared to controls (p < 0.05). CM patients with stage II had lower PMA levels than stages I and III (p < 0.05). High PMA levels were observed in patients with LN (+) compared to the LN (-) group (p < 0.0001). Patients with SSM had high levels of sCD40L and sCD62P compared to controls (p < 0.05)). High sCD40L levels in stage II compared to the stage III group, and sCD62P in stages I and II compared to the stage III group (p < 0.05). High sCD62P levels in patients with LN (-) compared to the group LN (+) (p < 0.05). It was observed the immunosuppressive profile in CM may favor tumor progression. High levels of platelet-leukocyte aggregates, sCD40L, and sCD62P may be associated with the worst prognosis.

A produção científica nas instituições da Rede Memorial de Pernambuco

This article analyzes the scientific production on Pernambuco’s Memorial Network institutions in the field of Information Science. A descriptive bibliographic research using bibliometric and thematic analysis was conducted with 17 articles indexed on Information Science Database. A total of eight Memory Institutions were analyzed: Superintendência do Desenvolvimento do Nordeste, Laboratório Liber de Tecnologia do Conhecimento, Memorial da Justiça de Pernambuco, Fundação Joaquim Nabuco, Biblioteca Pública do Estado de Pernambuco, Paço do Frevo, Arquivo Público do Estado Jordão Emerenciano and Memorial Denis Bernardes. The study identified 32 authors, of which 50% are linked to the Federal University of Pernambuco. Of these, three are among the most productive and are professors at the university’s Department of Information Science. Ágora, Em Questão and Revista Brasileira de Biblioteconomia e Documentação were the most recurring journals, indicating a significant number of publications with good evaluation by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior. The research brings contributions to Information Science by highlighting productions by these Memory Institutions and their developments for society and academia, such as sociocultural elements, the prioritization of studies focused on the state of origin, the integration of multiple competencies, interdisciplinarity, the democratization of knowledge and new knowledges produced by these spaces.

Evaluation of soluble co-inhibitors and co-stimulators levels of the immune response in gastric cancer.

Co-inhibitor and co-stimulatormediators trigger actions that result in immunological homeostasis and are being evaluated as potential therapeutic targets in gastric cancer (GC). To evaluate the soluble levels of sPD-1, sPD-L1, sPD-L2, sTIM-3, sGal9, sGITR, and sGITRL in GC patients. The cross-sectional study was carried out at the Hospital de Cancer de Pernambuco, Brazil between 2017 and 2018. A total of 74 GC patients and 30 healthy controls were included. Low levels of sPD1 (p = 0.0179), sPDL2 (p = 0.0003), and sGal9 (p < 0.0001), and higher levels of sPDL1 (p = 0.004), sTIM-3 (p = 0.0072), sGITR (p = 0.0179), and sGITRL (p = 0.0055) compared to the control group. High sPD-1, sTIM-3, and sGal9 levels in stage IV compared I/II and III (p < 0.05). High sPDL1, sGal9, and sGITRL levels in esophagogastric junction compared to body and Pylorus/Antrum groups (p < 0.05). No significant differences were observed in sPD1, sPDL1, sPDL2, sTIM3, sGal9, sGITR, and sGITRL levels between the intestinal, diffuse, and mixed GC groups. Low sGITR levels in GC patients who died within the first 24 months compared to the who survived (p = 0.0332). There is an association of sPD1, sTIM-3, and sGal9 with disease progression and sGITR with death, these mediators may be potential prognostic biomarkers in GC.

Progression of valve heart disease in a cohort of patients undergoing renal replacement therapy.

Cardiovascular disease is an important cause of death among patients with chronic kidney disease (CKD). Valve calcification is a predictor of cardiovascular mortality and coronary artery disease. To assess heart valve disease frequency, associated factors, and progression in CKD patients. We conducted a retrospective study on 291 CKD patients at Hospital das Clínicas de Pernambuco. Inclusion criteria were age ≥ 18 with CKD and valve disease, while those on conservative management or with missing data were excluded. Clinical and laboratory variables were compared, and patients were categorized by dialysis duration (<5 years; 5-10 years; >10 years). Statistical tests, including chi-square, Fisher's exact, ANOVA, and Kruskal-Wallis, were employed as needed. Simple and multivariate binary regression models were used to analyze valve disease associations with dialysis duration. Significance was defined as p < 0.05. Mitral valve disease was present in 82.5% (240) of patients, followed by aortic valve disease (65.6%; 86). Over time, 106 (36.4%) patients developed valve disease. No significant association was found between aortic, pulmonary, mitral, or tricuspid valve disease and dialysis duration. Secondary hyperparathyroidism was the sole statistically significant factor for mitral valve disease in the regression model (OR 2.59 [95% CI: 1.09-6.18]; p = 0.031). CKD patients on renal replacement therapy exhibit a high frequency of valve disease, particularly mitral and aortic valve disease. However, no link was established between dialysis duration and valve disease occurrence or progression.

Uso de agrotóxicos em canaviais de Pernambuco e danos à saúde do trabalhador

ABSTRACT This study aims to analyze exposure to pesticides and harm to the health of workers on sugarcane plantations in Pernambuco. This participatory research was conducted in rural territories of five municipalities with a strong presence in sugarcane-planted areas. The primary data were produced in workshops with rural workers to construct a participatory rural diagnosis, analyzed through condensation of meanings, and interpreted in light of the theoretical framework of Latin American critical epidemiology. The results are presented in three sections: i) Flowchart of work on sugarcane plantations; ii) Exposure to pesticides used on crops; iii) Harm to worker’s health. We conclude that permanent exposure to pesticides involves working on sugarcane plantations and emerges from a historical and socio-environmental construct in which the ways of life of the territories under the control of sugarcane agribusiness are subsumed. Public policies are recommended to promote family farming with diversification, flow, distribution of agroecological production, and strengthening primary health care and integrated epidemiological, health, environmental, and worker surveillance actions.

The Axiidea in the Museum of Oceanography Petrônio Alves Coelho, Recife, Brazil, with Some Remarks on the Biology of the Species

Axiidea housed in the collection of the Museu de Oceanografia Prof. Petrônio Alves Coelho, Universidade Federal de Pernambuco (MOUFPE) were studied. This collection contains 66% of the total diversity of axiideans recorded from the continental shelf of the Brazilian coast. The species are listed by family and genus as follows: Axiidea: Axiidae (Axiopsis, Axiorygma, Calaxius, Coralaxius, Manaxius, Paraxiopsis), Callianassidae (Cheramoides), Callichiridae (Callichirus, Corallianassa, Lepidophthalmus, Neocallichirus), Ctenochelidae (Ctenocheles, Ctenocheloides, Dawsonius, Gourretia), Micheleidae (Marcusiaxius, Meticonaxius). Details on the biology and taxonomy of some of these species are given. In addition, certain poorly documented species are now better understood.

Abstract PO4-24-10: Prognostic role of SOX2 and STAT3 expression on circulating T lymphocytes and CD44+/CD24neg cells in the locally advanced and metastatic breast cancer

Abstract Introduction: Breast cancer (BC) is associated with a continuous increase in incidence, with high mortality rates in several countries. There are four immunophenotypes of BC, luminal A, luminal B, triple negative (TN), and HER2+. Some proteins in tumor cells and the tumor microenvironment are part of tumorigenesis and metastases. The CD44 molecule is considered an important marker of the inflammatory response. CD44 is present in all leukocytes and on the surface of tumor stem cells, involving tumor invasion and metastasis. Some authors have demonstrated that the signal transducer and activator of transcription 3 (STAT3) and sex-determining region Y-related group box 2 (SOX2) are related to the regulation of somatic cell division and tumorigenesis and metastasis in BC. Aim: To evaluate SOX2 and STAT3 expression on circulating T lymphocytes and CD44+/CD24neg cells in locally advanced and metastatic breast cancer. Methods: A cross-sectional study was conducted at the Hospital de Cancer de Pernambuco (HCP) and the Translational Research Laboratory of the Instituto de Medicina Integral Prof. Fernando Figueira (IMIP) from March 2017 to April 2018. Sixty-five women diagnosed with breast cancer participated in this study, aged between 28 and 64. Of these, 51 women had stage III (locally advanced) breast tumors, and 14 with metastatic disease (stage IV). There were 24 healthy women aged 18 to 65 as a control group. The analysis of CD44, SOX2, and STAT3 expression was performed by flow cytometry. Results: elevated levels of CD44+/CD24neg cells and CD44+/CD24neg/SOX2+ cells were observed in the blood of BC patients with luminal B, HER2+, and TN compared to the control group (p&amp;lt; 0.0001). Low CD44+/CD24neg/STAT3+ levels in the patient's blood compared to the control group. Elevated CD44+/CD24neg and CD44+/CD24neg/STAT3+ cells were observed in locally advanced BC compared to metastatic group (p &amp;lt; 0.05). Patients with TNBC had elevated SOX2+T lymphocyte levels compared to luminal B and HER2+ subtypes groups (p&amp;lt; 0.05). HER2+ patients had low levels of T lymphocytes and SOX2+T cells compared to controls and luminal A groups (p &amp;lt; 0.05). High levels of total T cells (p=0.0007) and low SOX2+T lymphocytes (p=0.02) in locally advanced compared to metastatic disease (stage IV). Elevated levels of SOX2+T lymphocytes in patients with negative lymph nodes (N0) compared to N1 and N2 groups (p=0.004 and p &amp;lt; 0.0001, respectively). High levels of CD44+/CD24negSTAT3+ cells and T lymphocytes and low levels of STAT3+T lymphocytes in locally advanced TN subtype (stage III) compared to metastatic (stage IV). Conclusion: SOX2 and STAT3 expression on circulating T lymphocytes and CD44+/CD24neg cells in peripheral blood are prognostic roles in breast cancer. SOX2 and STAT3 expression are potential predictive biomarkers of disease progression in breast cancer regardless of tumor subtype. Investigating these biomarkers in peripheral blood has some advantages because peripheral blood collection is less invasive, easy to access, and allows evaluation at diagnosis, during treatment, and in cases of recurrence. Citation Format: Denise Viana, Victor Andrade, Marcelo Salgado, Carolina Vasconcelos, Leuridan Torres. Prognostic role of SOX2 and STAT3 expression on circulating T lymphocytes and CD44+/CD24neg cells in the locally advanced and metastatic breast cancer [abstract]. In: Proceedings of the 2023 San Antonio Breast Cancer Symposium; 2023 Dec 5-9; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2024;84(9 Suppl):Abstract nr PO4-24-10.

Abstract PO3-25-06: Expression of CD28, Fas, PD1, and CTLA4 molecules on cellular immune response in the blood peripheral of patients with locally advanced triple-negative breast cancer

Abstract Background: Locally advanced triple-negative breast cancer (TNBC) represents a public health problem in Brazil; its standard treatment consists of neoadjuvant chemotherapy followed by surgical and radiotherapy, with highly variable success rates are depended on access to appropriate cancer treatment, and the type of pathological response. In the last decade, the immune system's role in breast cancer has gained space by demonstrating the favorable impact of lymphocyte tumor infiltrate (TILs) and gene expression of the immune response, especially in tumors with high proliferation rates and negative estrogen receptors. The cellular immune response is regulated by co-stimulatory and co-inhibitory proteins such as CD28, Fas, PD1, and CTLA4 molecules. Methods: This was a longitudinal study with follow-up performed between 2015 and 2017. The study was conducted at the Hospital de Cancer de Pernambuco and Translational Research Laboratory of the Instituto de Medicina Integral Prof. Fernando Figueira (IMIP). Thirty women (18 to 60 years) diagnosed with locally advanced TNBC submitted to neoadjuvant chemotherapy (NAC), and 30 healthy women as a control group were included. The co-stimulatory and co-inhibitory proteins analyses were performed in the peripheral blood of TNBC women before (Pre-NAC) and after NAC (Post-NAC) Results: High levels of CD28+CD3+ T, CD28+CD4+ T, PD1+CD3+ T, and CTLA4+CD3+ T cells in the pathological complete response (pCR) and non-pCR groups compared to the control group (p &amp;lt; 0.05). High levels of Fas+CD4+T cells and PD1+CD8+T cells in the non-pCR compared to the pCR group (p &amp;lt; 0.05). In the paired analysis, significant differences were observed in CD3+T and CD4+T levels with CD28, Fas, and PD1 expression between pre- and post-NAC. Conclusion: Fas+CD4+T and PD1+CD8+T levels in peripheral blood in TNBC are associated with pCR, suggesting potential predictive biomarkers of NAC response. Preliminary results allow us to infer that neoadjuvant chemotherapy modulates the cellular immune response in TNBC women. Citation Format: Marcelo Salgado, Fernando Soares, Denise Viana, Amanda Salgado, Carolina Vasconcelos, Carlos Eduardo Anunciação, Eduardo Salgado, Leuridan Torres. Expression of CD28, Fas, PD1, and CTLA4 molecules on cellular immune response in the blood peripheral of patients with locally advanced triple-negative breast cancer [abstract]. In: Proceedings of the 2023 San Antonio Breast Cancer Symposium; 2023 Dec 5-9; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2024;84(9 Suppl):Abstract nr PO3-25-06.

Endodontic Intercurrences in The Coronal Opening During The Covid-19 Pandemic: A Cross-sectional Study

Objective: This research aimed to assess the impact of the suggestion of changing the clinical moment for the installation of rubber dam isolation during the COVID-19 pandemic, during the graduation period in Faculdade de Odontologia de Pernambuco, Universidade de Pernambuco (FOP/UPE). Materials and methods: This is an observational descriptive, cross-sectional survey of a quantitative nature, which aims to identify the main impacts of the suggestion of changing the clinical moment for the installation of rubber dam isolation in endodontic procedures, which was approved by the Ethics Committee in Research of the University of Pernambuco (CEP/UPE), under allowance ethics committee number CAAE: 47786521.4.0000.5207. The population of this research consisted of FOP/UPE undergraduate students, regularly enrolled from the 6th to the 10th period, in the years 2021 and 2022, and who accomplished dental coronal opening in endodontic treatments, in the practicing clinics of the university during the pandemic period. Information was collected through a questionnaire the researchers prepared, using the online forms application named Google Forms. Results: Only 6.7% identified intercurrences during coronal opening, restricted to difficulties in accessing the pulp chamber. Conclusion: It is understood, therefore, that the suggestions for changing the endodontic care protocol related to the prior installation of rubber dam isolation to the coronal opening procedure were used and did not increase the risk of operative complications by FOP/UPE academics, in the clinics-school during the COVID-19 pandemic.

Molecular Verification of Trichophyton in the Brazilian URM Culture Collection.

Trichophyton species cause dermatophytosis in humans, with a high, worldwide frequency of reports and important public health relevance. We evaluated 61 Trichophyton strains from different sources deposited in the University Recife Mycology (URM) culture collection of the Universidade Federal de Pernambuco, Brazil. Strains were phenotypically identified and confirmed by sequencing Internal Transcribed Spacers rDNA and partial beta-tubulin 2-exon. Additionally, we evaluated their susceptibility to terbinafine and itraconazole. Physiological analyses included urease activity and growth in casein medium. Phenotypic methods allowed the reliable identification of T. rubrum only, whereas, for other species, molecular methods were mandatory. All Trichophyton species exhibited susceptibility profiles to itraconazole (0.04-5.33μg/mL) and terbinafine (0.17-3.33μg/mL). Our analyses revealed a heterogeneous distribution of T. mentagrophytes, which does not support the current distribution within the species complex of T. mentagrophytes and its genotypes.

Microplastics in Brazilian coastal environments: a systematic review

This systematic review aimed to evaluate the current scenario of research on microplastics (MPs) in Brazilian coastal environments, considering beaches and also environments not yet reported in previous reviews, such as estuaries, mangroves, and reefs. Five databases were consulted, and 102 articles on the subject published between 2018 and 2023 were selected. The universities and research institutions that most published in this period were from the Southeast region (37.3% of the articles), followed by the Northeast region (34.3%). Universities in the states of Rio de Janeiro (15.7%) and Pernambuco (15.7%) lead the number of publications, followed by São Paulo (11.8%), Rio Grande do Sul (11.8%), and Espírito Santo (7.8%). About the coastal environments studied, 70% of the studies evaluated the presence of MPs on beaches, 26% on mangroves, 2% on estuaries, and 2% on coral reefs. Studies that evaluated its presence in marine biota corresponded to 43% of the articles, sediment (42%), and water (14%). The most studied organisms were bony fish (42%), bivalves (17%), crustaceans (7%), seabirds (7%), turtles (7%), and microfauna (5%). Despite growing, the distribution of study locations is still uneven and not related to the length of the coastline of each state. As for the origin, the works compiled in this study infer that the main sources of PMs are tourism, fishing, and river discharge, while the action of waves and winds contributes to the dispersion of these particles to less urbanized beaches and remote locations.

Preoperative hypovitaminosis D and complications in plastic surgery: a pilot study.

Vitamin D plays a crucial role in various biological processes, including the well-known regulation of the immune system and calcium metabolism. While its involvement in the surgical outcomes of various medical specialties is recognized, there is a lack of consistent data regarding plastic surgery. This study aimed to assess preoperative serum levels of 25-hydroxyvitamin D and its relationship with complications in patients undergoing reconstructive and aesthetic plastic surgeries. prospective and observational cohort study, conducted from October 2021 to August 2023 at the Hospital das Clínicas, Universidade Federal de Pernambuco, involving 83 patients. vitamin D levels were deemed deficient in 7 (8,4%) patients, insufficient in 36 (43,4%), and sufficient in 40 (48,2%). No direct association was demonstrated between deficient or insufficient serum levels of 25-hydroxyvitamin D and the incidence of complications in plastic surgery, even when considering comorbidities. preoperative hypovitaminosis D was not associated with complications in plastic surgery.

Impressão 3D na relação médico-paciente, relato de experiência da integração entre ensino, inovação e assistência

ABSTRACT Introduction: In the literature, several articles demonstrate patient satisfaction and better understanding of the information transmitted by the medical team, with the aid of three-dimensional pieces. Education and health are inseparable and interdependent practices, they have always been articulated, and considered crucial elements in the action process of health professionals. Thus, teachers and students of the medicine course at Universidade Federal de Pernambuco created a university extension project that aimed at the use of anatomical models printed in 3D, for the education of patients in the orthopedics and traumatology outpatient clinic. Experience Report: Over the six months of the project, 77 patients were assisted and the project employed the work of 3 teachers and 18 undergraduate students, totaling 98 people involved in the project. The actions were divided into 2 blocks: the first consisted of training the students and, in the second, the students visited the outpatient clinic, accompanied by a specialist physician in charge and used pieces printed by the students themselves, to guide the patients regarding their respective condition and provided guidance on therapy using these printed pieces. Discussion: the possibility of using this tool as an aid in medical communication opens up a vast horizon of application of 3D printing in health education. This, in turn, favors the improvement of health promotion in less developed regions, since this interaction between the health team and the community allows the promotion, protection and recovery of health, based on a horizontal dialogue, valuing and respecting the users of the health system, aiming to make them an agent and protagonist of the health and disease process. Conclusion: It can be concluded, therefore, that extension projects such as this one have enormous potential to generate impacts on medicine, the academic community and the assisted population, especially the less educated ones.

Developing a Model to Improve the Efficiency of Maintenance Management for Service Buildings Using BIM and Power BI: A Case Study

Developing a Model to Improve the Efficiency of Maintenance Management for Service Buildings Using BIM and Power BI: A Case Study

EVALUATION OF THE MORPHOLOGICAL PATTERNS OF THE LIPS IN A PORTION OF THE POPULATION

The objective of this research was to identify the morphological patterns of the furrows in lip prints, of the commissures and the thickness of the lips through a cheiloscopic study, as well as correlating them with the individual characteristics of each volunteer, like for instance, gender, age, and body mass index. The sample was made up of 1,016 volunteers that were patients being attended to at the clinics of the Faculdade de Odontologia da Universidade de Pernambuco (FOP/UPE). To begin with, height (cm) and weight (kg) were measured, followed by a calculation of body mass index on an individual basis. Lip prints were obtained using wax paper, measuring the thickness of the lips, and two photographs were taken to analyze the arrangement of the lips. In relation to the lip arrangement, the horizontal form was the most prevalent in the population studied (59.6%). In terms of classification of lip thickness, the standard most found amongst upper lips was that of thin (60.4%) and for lower lips was that of thick (40.6%). It was also found that the percentage of people who were classified as having thin lips, both upper and lower, increased as the age ranges went up. According to the Suzuki and Tsuchihashi classification, type II was the most found and type V was the least found amongst the whole group, presenting variations in relation to the sub quadrants and gender. It can be concluded that from the analysis of the studied variables, we can identify the morphological standards, as well as their correlations with the other individual characteristics, with Cheiloscopy being an important tool in helping with human identification.

Solid waste management: an investigation on the current situation of the landfill in the municipality of Garanhuns – PE

The generation of solid residues has become one of the biggest problems of humanity due to the growing demand of the population for goods and services, and it is necessary that the governments look into a way to mitigate its harmful effects on the environment. In Brazil, the problem of adequate solid waste management also became recurrent and started with the United Nations Conference on Environment and Development, which took place in the city of Rio de Janeiro in 1992, Rio-92 or Eco-92. The general objective of the work is to diagnose the current situation of the Garanhuns landfill regarding its suitability for the Intermunicipal Solid Waste Plan - PIRS of the Agreste Meridional Region of Pernambuco and the Garanhuns landfill as an instrument to combat environmental transgression. In the first moment, a documentary analysis was carried out regarding the proposed theme and in the second moment, an investigation, through an interview, about the situation of the landfill in relation to the PIRS. Despite fulfilling some requirements regarding the final destination of the waste, the municipality has not yet prepared, licensed and implemented the Degraded Areas Recovery Program-PRAD, an indispensable part to comply with the guideline of “Compliance with the National Solid Waste Policy”. However, even though there are still some obstacles to compliance with the PIRS, the importance of a properly licensed landfill operating in Agreste Meridional de Pernambuco is emphasized.