Daytime Decrease Research Articles

Sleep hygiene intervention for youth aged 10 to 18 years with problematic sleep: a before-after pilot study

BackgroundThe current study aimed to examine the changes following a sleep hygiene intervention on sleep hygiene practices, sleep quality, and daytime symptoms in youth.MethodsParticipants aged 10–18 years with self-identified sleep problems completed our age-appropriate F.E.R.R.E.T (an acronym for the categories of Food, Emotions, Routine, Restrict, Environment and Timing) sleep hygiene programme; each category has three simple rules to encourage good sleep. Participants (and parents as appropriate) completed the Adolescent Sleep Hygiene Scale (ASHS), Pittsburgh Sleep Quality Index (PSQI), Sleep Disturbance Scale for Children (SDSC), Pediatric Daytime Sleepiness Scale (PDSS), and wore Actical® monitors twice before (1 and 2 weeks) and three times after (6, 12 and 20 weeks) the intervention. Anthropometric data were collected two weeks before and 20 weeks post-intervention.ResultsThirty-three youths (mean age 12.9 years; M/F = 0.8) enrolled, and retention was 100%. ASHS scores significantly improved (p = 0.005) from a baseline mean (SD) of 4.70 (0.41) to 4.95 (0.31) post-intervention, as did PSQI scores [7.47 (2.43) to 4.47 (2.37); p < 0.001] and SDSC scores [53.4 (9.0) to 39.2 (9.2); p < 0.001]. PDSS scores improved from a baseline of 16.5 (6.0) to 11.3 (6.0) post- intervention (p < 0.001). BMI z-scores with a baseline of 0.79 (1.18) decreased significantly (p = 0.001) post-intervention to 0.66 (1.19). Despite these improvements, sleep duration as estimated by Actical accelerometry did not change. There was however a significant decrease in daytime sedentary/light energy expenditure.ConclusionsOur findings suggest the F.E.R.R.E.T sleep hygiene education programme might be effective in improving sleep in children and adolescents. However because this was a before and after study and a pilot study with several limitations, the findings need to be addressed with caution, and would need to be replicated within a randomised controlled trial to prove efficacy.Trial registrationAustralian New Zealand Clinical Trials Registry: ACTRN12612000649819

Sensitivity of predicted pollutant levels to urbanization in China

Urbanization in China accompanies economic development and population growth. Changes in land use leads to changes in both meteorological and chemical fields. In this study, the impact of land use change in Jing-Jin-Ji (JJJ, indicating Beijing–Tianjin–Hebei) and Yangtze River Delta (YRD) areas on meteorology and ozone concentrations are studied using the WRF–Chem model. Land use change is represented by two different land cover data sets: USGS and MODIS. Monthly-average simulations show that urbanization causes an increase in 2-m temperature by maximum 2.4 °C and 3.2 °C in these two areas, respectively. Wind speed simulations suggest a decrease (average 1.2 m s−1) in daytime for YRD, and in nighttime for JJJ. Dew point differences show a dry effect over both areas, with maximum −3 °C in JJJ and −2.4 °C in YRD. Planetary Boundary Layer (PBL) height increases by 400 m (maximum in JJJ) and 600 m (maximum in YRD) for daytime, and nighttime increases are less than 100 m. Daytime ozone concentrations in JJJ increase by 20 ppb due to urbanization, while in YRD the difference is around 5 ppb. Compared to observations, mean errors in urban areas was improved when using updated land use information by 14.2% and 35.6%, and in suburban areas by 5.8% and 10.7%. Updating land use data set in air quality modeling is important in application to regions with rapid urbanization such as China. The effects due to land use change can be as large as those due to 20% increase in emissions.

Plasma corticosterone elevation inhibits the activation of nuclear factor kappa B (NFKB) in the Syrian hamster pineal gland

We evaluated how the mild stress-induced increase in endogenous corticosterone affected the pineal gland in Syrian hamsters (Mesocricetus auratus). The animals were maintained under constant light for 1 day, instead of a cycle of 14:10-h, to increase the circulating corticosterone levels during the daytime. The nuclear translocation of nuclear factor kappa B (NFKB), which is the pivotal transcription factor for stress and injury, presented a daily rhythm in normal animals. NFKB nuclear content increased linearly from the onset of light [Zeitgeber Time 0 (ZT0)] until ZT11 and decreased after ZT12 when the plasma corticosterone peak was detected in normal animals. However, the 24-h profiles of the two curves were different, and they did not clearly support an exclusive relationship between corticosterone levels and NFKB content. Therefore, we tested the effect of increased endogenous corticosterone through inducing mild stress by maintaining daytime illumination for one night. This stressful condition, which increased daytime corticosterone levels, resulted in a daytime decrease in NFKB nuclear content, and this was inhibited by mifepristone. Overall, this study shows that NFKB has a daily rhythm in Syrian hamster pineal glands and, by increasing endogenous corticosterone with a stressful condition, NFKB activity is regulated. Therefore, this study suggests that the pineal gland in the Syrian hamster is a sensor of stressful conditions.

Assessment of Vegetation Response to Drought in Nebraska Using Terra-MODIS Land Surface Temperature and Normalized Difference Vegetation Index

Eight-day composite Terra-MODIS cumulative LST and NDVI timeseries data were used to analyze the responses of crop and grassland cover types to drought in Nebraska. Four hundred ninety 1 km pixels that included irrigated and non-irrigated corn and soybeans and three grassland cover types were selected across the state of Nebraska. Statistical analyses revealed that the majority of the land cover pixels experienced significantly higher daytime and nighttime LSTs and lower NDVI during the drought-year growing season (p < 0.01). Among the land cover types analyzed, grassland experienced the highest increase in daytime LST and decrease in NDVI.

The Effects of Continuous Positive Airway Pressure on Prehypertension and Masked Hypertension in Men With Severe Obstructive Sleep Apnea

Obstructive sleep apnea and hypertension are common conditions that frequently coexist. Continuous positive airway pressure (CPAP) reduces blood pressure in patients with obstructive sleep apnea and sustained hypertension. However, the impact of CPAP on patients with obstructive sleep apnea and prehypertension and masked hypertension, conditions associated with increased cardiovascular risk, is unknown. Thirty-six male patients (age, 43 ± 7 years; body mass index, 28.8 ± 3.0 kg/m(2)) with untreated severe obstructive sleep apnea (apnea-hypopnea index, 56 ± 22 events/hr on polysomnography) with diagnostic criteria for prehypertension and/or masked hypertension, based on office and 24-hour ambulatory blood pressure monitoring, respectively, were studied. The patients randomized to no treatment (control; n=18) or CPAP (n=18) for 3 months had similar frequency of prehypertension and masked hypertension at study entry. There were no significant changes in blood pressure in patients randomized to the control group. In contrast, patients randomized to CPAP presented significant reduction in office systolic (from 126 ± 5 to 121 ± 7 mm Hg; P=0.001) and a trend for diastolic blood pressure (from 75 ±7 to 73 ± 8 mm Hg; P=0.08) as well as a significant decrease in daytime and nighttime systolic and diastolic blood pressure (P<0.05 for each comparison). There was a significant reduction in the frequency of prehypertension (from 94% to 55%; P=0.02) and masked hypertension (from 39% to 5%; P=0.04) only in the CPAP group. In conclusion, effective CPAP therapy promotes significant reduction in the frequency of prehypertension and masked hypertension by promoting significant blood pressure reductions in patients with severe obstructive sleep apnea.

Head position during resting modifies spontaneous daytime decrease of downbeat nystagmus

The intensity of downbeat nystagmus (DBN) decreases during the daytime when the head is in upright position. This prospective study investigated whether resting in different head positions (upright, supine, prone) modulates the intensity of DBN after resting. Eye movements of 9 patients with DBN due to cerebellar (n = 2) or unknown etiology (n = 7) were recorded with video-oculography. Mean slow-phase velocities (SPV) of DBN were determined in the upright position before resting at 9 am and then after 2 hours (11 am) and after 4 hours (1 pm) of resting. Whole-body positions during resting were upright, supine, or prone. The effects of all 3 resting positions were assessed on 3 separate days in each patient. Before resting (9 am), the average SPV ranged from 3.05 °/s to 3.6 °/s on the separate days of measurement. After resting in an upright position, the average SPV at 11 am and 1 pm was 0.65 °/sec, which was less (p < 0.05) than after resting in supine (2.1 °/sec) or prone (2.22 °/sec) positions. DBN measured during the daytime in an upright position becomes minimal after the patient has rested upright. The spontaneous decrease of DBN is less pronounced when patients lie down to rest. This indicates a modulation by otolithic input. We recommend that patients with DBN rest in an upright position during the daytime. This study provides Class II evidence that for patients with DBN 2 hours of rest in the upright position decreases nystagmus more than 2 hours of rest in the supine or prone positions (relative improvement 79% upright, 33% supine, and 38% prone: p < 0.05).

Weakening sensible heat source over the Tibetan Plateau revisited: effects of the land–atmosphere thermal coupling

The bulk heat transfer coefficient (C H ) indicates the land–atmosphere thermal coupling strength. We seek to detect its variability and changes on the Tibetan Plateau (TP) during 1981–2006, particularly concerned with its effects on the sensible heat source. C H is parameterized by Monin–Obukhov similarity theory combining routine meteorological measurements. The South Asian monsoon period is characterized by weak sensible heat flux (H), but strong thermal coupling (C H ). Winter sees the greatest diurnal C H range, roughly 0.001–0.008. On average, C H exhibits a notable nighttime increase (10% decade−1) and a weak daytime decrease (−5% decade−1). The strengthening thermal coupling at selected sites alleviates the weakening of H, because it enhances nighttime H increase and reduces daytime H decrease. Moreover, we confirm the finding in earlier studies that sensible heating is weakening on the TP, but find its trend less notable than empirically estimated using C H = 0.004.

Influence of microbial photosynthesis on tufa stromatolite formation and ambient water chemistry, SW Japan

Photosynthetic influences on tufa stromatolite formation and ambient water chemistry were investigated at two well-studied streams depositing tufa in Southwestern Japan (Shirokawa and Shimokuraida). The tufa stromatolites in both streams are composed of fine-grained calcite crystals showing annual lamination, and colonized by a number of filamentous cyanobacteria as well as non-phototrophic bacteria. Microelectrode measurements of pH, O 2, and Ca 2+ near the stromatolite surface (the diffusive boundary layer; DBL) revealed that the investigated tufa stromatolites are formed by photosynthesis-induced CaCO 3 precipitation (PCP): cyanobacterial photosynthesis induces calcite precipitation under light conditions, while respiration of cyanobacteria and non-phototrophic bacteria inhibits precipitation in the dark. The bulk water chemistry at the lower sites of the investigated streams showed the daytime decreases of Ca 2+ concentration and alkalinity that was expected for significant influence of PCP, while the other expected change, increased pH, was not observed. In order to examine this discrepancy, a novel approach using semi- in situ microelectrode measurements was applied to perform precise quantitative calculations. The calculation results demonstrated that the observed Ca 2+ concentration and alkalinity decreases were caused by PCP, and that the concomitant pH increase was expected to be under the detection level of a conventional pH meter. Although the amount of PCP is supposed to be significantly affected by light intensity, observations in Shimokuraida revealed that the amount of PCP on cloudy day nonetheless accounted for about 80% of that on sunny day. Despite the significant role of PCP for tufa stromatolite formation, PCP accounted for only about 10% of the precipitated calcite in the investigated streams, which indicates that tufa stromatolites, the characteristic deposits in the streams, are responsible for only a small portion of calcite precipitation, and the rest is considered to precipitate inorganically at biofilm-free substrates.

Acute effects of melatonin and its time of administration on core body temperature and heart rate in cynomolgus monkeys

We examined the effects of exogenous melatonin and the time of its administration on core body temperature (CBT) and heart rate (HR) in cynomolgus monkeys. Doses of melatonin at 0.2, 2, 20 and 200 mg/kg were administered by oral gavage once daily at different times. With administration at 09.00 h, melatonin dose-dependently suppressed CBT and the effect reached statistical significance at 200 mg/kg. With administration at 16.00 h, the suppressive effect on CBT was not evident for several hours after administration possibly due to masking by the normal robust CBT decline. Unexpectedly, melatonin inhibited the normal CBT decline thereafter and this resulted in an upward shift of the CBT nadir during the dark phase especially with 200 mg/kg. The HR showed a similar upward shift at that time. Any effects on the CBT and HR from melatonin administration were not inhibited by luzindole, an MT(1)/MT(2) receptor antagonist, whereas N-acetyl-5-hydroxytryptamine, a ligand of the MT(3) binding site, mimicked all the actions of melatonin. To our knowledge, this is the first time it has been shown that melatonin administered in the early evening promotes upward shifting of the CBT and HR in the nighttime in addition to the daytime decrease in the CBT. These changes may be mediated, at least partly, through the MT(3) binding site.

A Major Role for Perifornical Orexin Neurons in the Control of Glucose Metabolism in Rats

OBJECTIVEThe hypothalamic neuropeptide orexin influences (feeding) behavior as well as energy metabolism. Administration of exogenous orexin-A into the brain has been shown to increase both food intake and blood glucose levels. In the present study, we investigated the role of endogenous hypothalamic orexin release in glucose homeostasis in rats.RESEARCH DESIGN AND METHODSWe investigated the effects of the hypothalamic orexin system on basal endogenous glucose production (EGP) as well as on hepatic and peripheral insulin sensitivity by changing orexinergic activity in the hypothalamus combined with hepatic sympathetic or parasympathetic denervation, two-step hyperinsulinemic-euglycemic clamps, immunohistochemistry, and RT-PCR studies.RESULTSHypothalamic disinhibition of neuronal activity by the γ-aminobutyric acid receptor antagonist bicuculline (BIC) increased basal EGP, especially when BIC was administered in the perifornical area where orexin-containing neurons but not melanocortin-concentrating hormone–containing neurons were activated. The increased BIC-induced EGP was largely prevented by intracerebroventricular pretreatment with the orexin-1 receptor antagonist. Intracerebroventricular administration of orexin-A itself caused an increase in plasma glucose and prevented the daytime decrease of EGP. The stimulatory effect of intracerebroventricular orexin-A on EGP was prevented by hepatic sympathetic denervation. Plasma insulin clamped at two or six times the basal levels did not counteract the stimulatory effect of perifornical BIC on EGP, indicating hepatic insulin resistance. RT-PCR showed that stimulation of orexin neurons increased the expression of hepatic glucoregulatory enzymes.CONCLUSIONSHypothalamic orexin plays an important role in EGP, most likely by changing the hypothalamic output to the autonomic nervous system. Disturbance of this pathway may result in unbalanced glucose homeostasis.

Air Pollution Transport in an Alpine Valley: Results From Airborne and Ground-Based Observations

An observational dataset from a wintertime field campaign in the Inn Valley, Austria, is analysed in order to study mechanisms of air pollution transport in an Alpine valley. The results illustrate three types of mechanisms: transport by a density current, back-and-forth transport by valley winds, and transport by slope winds. The first type is associated with an air mass difference along the valley. Cooler air located in the lower part of the valley behaves like a density current and produces the advection of pollutants by upvalley winds. In the second type, strong horizontal gradients in pollution concentrations exist close to ground. Multiple wind reversals result in a back-and-forth transport of pollutants by weak valley winds. In the third type, upslope winds during daytime decrease low-level pollution concentrations and cause the formation of elevated pollution layers.

Daily ration and feeding activity of juvenile hake in the central Mediterranean Sea

We investigated daily ration, feeding rhythms and gastric evacuation rates of juvenile (&lt;16 cm total length) European hake Merluccius merluccius, using stomach samples collected during four 24-hour trawl surveys carried out in 2001–2002 on the continental shelf-break (from 120 m to 160 m in depth) off the western coast of central Italy (central Mediterranean Sea). In each survey 8 hauls of 30 minutes were performed every three hours throughout the 24-hour period to cover the entire diel cycle. Diet of juvenile hake was mostly composed of the euphausiid Nyctiphanes couchii, showing a peak in stomach contents during early morning followed by a daytime decrease. Fullness index (%FI) was generally higher during sunrise when migratory activity ceased and juvenile hake return to the bottom after feeding. Concerning the hake abundance the highest density value was obtained in May during the recruitment period.Two independent daily ration estimates were produced. First, an empirical attempt to estimate the daily amount of food consumed was obtained by back-calculating the fresh weight of euphausiid prey ingested by juvenile hake. Estimated values ranged from 4.96–5.89% body wet weight (%BW). Second, the daily ration was computed applying the exponential gastric evacuation models proposed by Elliot &amp; Persson (1978) and Eggers (1979). Daily ration values obtained using these consumption models produced a considerable (15–20%) underestimation of consumption rate for juvenile hake.

Temporary decrease in daytime F‐region peak electron density due to eastward electric field penetration during magnetic storm

While a prompt penetration of an eastward electric field during a magnetic storm is known to increase the F‐region electron density, observations have shown that the F‐region peak density (NmF2) sometimes decreases before it increases, although total electron content (TEC) begins increasing immediately after the electric field penetration. We investigated potential mechanisms of the observed NmF2 decrease as well as of the TEC increase. Simulation showed that increased upward or downward diffusion flux in the topside ionosphere caused by layer uplift temporarily reduces the F‐region density at midlatitudes (mechanism A). In addition, the E × B motion toward an outer L shell region leads to flux tube expansion and plasma dilution, which also contribute to the NmF2 decrease (mechanism B). The TEC increase can be attributed to quick plasma production below the uplifted F2 peak. Simulation also showed that penetration events with an electric field magnitude greater than several mV/m can cause such a phenomenon. We also examined preferable conditions for this phenomenon, and found that degree of NmF2 decrease tends to become significant due to effect of mechanism A if a prompt electric field penetration occurs in the early morning or if the plasma temperature is high enough in the topside ionosphere.

Urban Canopy Modeling of the New York City Metropolitan Area: A Comparison and Validation of Single- and Multilayer Parameterizations

Abstract High-resolution numerical simulations are conducted using the Coupled Ocean–Atmosphere Mesoscale Prediction System (COAMPS)1 with two different urban canopy parameterizations for a 23-day period in August 2005 for the New York City (NYC) metropolitan area. The control COAMPS simulations use the single-layer Weather Research and Forecasting (WRF) Urban Canopy Model (W-UCM) and sensitivity simulations use a multilayer urban parameterization based on Brown and Williams (BW-UCM). Both simulations use surface forcing from the WRF land surface model, Noah, and hourly sea surface temperature fields from the New York Harbor and Ocean Prediction System model hindcast. Mean statistics are computed for the 23-day period from 5 to 27 August (540-hourly observations) at five Meteorological Aviation Report stations for a nested 0.444-km horizontal resolution grid centered over the NYC metropolitan area. Both simulations show a cold mean urban canopy air temperature bias primarily due to an underestimation of nighttime temperatures. The mean bias is significantly reduced using the W-UCM (−0.10°C for W-UCM versus −0.82°C for BW-UCM) due to the development of a stronger nocturnal urban heat island (UHI; mean value of 2.2°C for the W-UCM versus 1.9°C for the BW-UCM). Results from a 24-h case study (12 August 2005) indicate that the W-UCM parameterization better maintains the UHI through increased nocturnal warming due to wall and road effects. The ground heat flux for the W-UCM is much larger during the daytime than for the BW-UCM (peak ∼300 versus 100 W m−2), effectively shifting the period of positive sensible flux later into the early evening. This helps to maintain the near-surface mixed layer at night in the W-UCM simulation and sustains the nocturnal UHI. In contrast, the BW-UCM simulation develops a strong nocturnal stable surface layer extending to approximately 50–75-m depth. Subsequently, the nocturnal BW-UCM wind speeds are a factor of 3–4 less than W-UCM with reduced nighttime turbulent kinetic energy (average &amp;lt; 0.1 m2 s−2). For the densely urbanized area of Manhattan, BW-UCM winds show more dependence on urbanization than W-UCM. The decrease in urban wind speed is most prominent for BW-UCM both in the day- and nighttime over lower Manhattan, with the daytime decrease generally over the region of tallest building heights while the nighttime decrease is influenced by both building height as well as urban fraction. In contrast, the W-UCM winds show less horizontal variation over Manhattan, particularly during the daytime. These results stress the importance of properly characterizing the urban morphology in urban parameterizations at high resolutions to improve the model’s predictive capability.

Interaction of hydrology and nutrient limitation in the Ridge and Slough landscape of the southern Everglades

Extensive portions of the southern Everglades are characterized by series of elongated, raised peat ridges and tree islands oriented parallel to the predominant flow direction, separated by intervening sloughs. Tall herbs or woody species are associated with higher elevations and shorter emergent or floating species are associated with lower elevations. The organic soils in this “Ridge-and-Slough” landscape have been stable over millennia in many locations, but degrade over decades under altered hydrologic conditions. We examined soil, pore water, and leaf phosphorus (P) and nitrogen (N) distributions in six Ridge and Slough communities in Shark Slough, Everglades National Park. We found P enrichment to increase and N to decrease monotonically along a gradient from the most persistently flooded sloughs to rarely flooded ridge environments, with the most dramatic change associated with the transition from marsh to forest. Leaf N:P ratios indicated that the marsh communities were strongly P-limited, while data from several forest types suggested either N-limitation or co-limitation by N and P. Ground water stage in forests exhibited a daytime decrease and partial nighttime recovery during periods of surface exposure. The recovery phase suggested re-supply from adjacent flooded marshes or the underlying aquifer, and a strong hydrologic connection between ridge and slough. We therefore developed a simple steady-state model to explore a mechanism by which a phosphorus conveyor belt driven by both evapotranspiration and the regional flow gradient can contribute to the characteristic Ridge and Slough pattern. The model demonstrated that evapotranspiration sinks at higher elevations can draw in low concentration marsh waters, raising local soil and water P concentrations. Focusing of flow and nutrients at the evapotranspiration zone is not strong enough to overcome the regional gradient entirely, allowing the nutrient to spread downstream and creating an elongated concentration plume in the direction of flow. Our analyses suggest that autogenic processes involving the effects of initially small differences in topography, via their interactions with hydrology and nutrient availability, can produce persistent physiographic patterns in the organic sediments of the Everglades.

Aldosterone Antagonism in Chronic Kidney Disease

Angiotensin-converting enzyme (ACE) inhibitors are potent members of the arsenal to treat chronic kidney disease (CKD). By reducing blood pressure (BP) and disproportionately decreasing intraglomerular pressure, this class of drugs also reduces proteinuria and slows progression of CKD (1,2). Given the high prevalence of cardiovascular disease in this population, it is noteworthy that ACE inhibitors also decrease the incidence of stroke, myocardial infarction (MI), and cardiovascular mortality in patients who are at high cardiovascular risk (3). More recently, data reporting similar benefits of angiotensin receptor blockers (ARB) support their use in the treatment of CKD as well, especially in individuals with type 2 diabetes (4). Furthermore, one sizable study suggested that the combination of an ACE inhibitor and ARB may be more effective than either agent alone (5). Parving and colleagues (6) called attention to the effects of high-dose ARB therapy, up to three times the recommended dose, as an additional means of effectively interrupting the renin-angiotensin-aldosterone system (RAAS). By logical extension, further blockade of the RAAS by direct antagonism of aldosterone also may prove beneficial. Indeed, aldosterone seems to be a potent effector of renal injury (7–9). In the rare cases of primary aldosteronism and its functional analogue, the even more rare Liddle’s syndrome, the observed renal injury probably is independent of the more proximal elements of the RAAS (10,11). Animal models provide an expeditious tool for assessing pathophysiologic change and the efficacy of intervention. The classic model of primary aldosteronism, the mineralocorticoid–nephrectomy–high-salt model of hypertension, develops systemic and glomerular capillary hypertension and sustains renal damage (12). In the remnant kidney model of CKD, ACE inhibitors and ARB attenuate renal injury (13). However, this protection, which is associated with suppression of aldosterone secretion, is abrogated by exogenous aldosterone infusion with return of …

Weekday/Weekend Differences in Ambient Air Pollutant Concentrations in Atlanta and the Southeastern United States

The authors quantified changes between mean weekday and weekend ambient concentrations of ozone (O3) precursors (volatile organic compounds [VOC], carbon monoxide [CO], nitric oxide, and oxides of nitrogen [NOx]) in Atlanta and surrounding areas to observe how weekend precursor emission levels influenced ambient O3 levels.The authors analyzed CO, nitric oxide (NO), and NOx measurements from 1998 to 2002 and speciated VOC from 1996 to 2003. They observed a strong weekend effect in the Atlanta region, with median daytime (6:00 a.m. to 3:00 p.m. Eastern Standard Time) decreases of 62%, 57%, and 31%, respectively, in the ambient levels of NO, NOx,and CO from Wednesdays to Sundays, during the ozone season (March to October). They also observed significant decreases in ambient VOC levels between Wednesdays and Sundays, with decreases of 28% for the sum of aromatic compounds and 19% for the sum of Photochemical Assessment Monitoring Stations target compounds. Despite large reductions in O3 precursor levels on weekends, day-of-week differences in O3 mixing ratios in and near Atlanta were much smaller. Averaging overall O3-season days, the 1-hr and 8-hr mean peak daily O3 maxima on Sundays were 4.5% and 2.3% lower, respectively, than their mean levels on Wednesdays (median of 14 site differences), with no sites showing statistically significant Wednesday-to-Sunday differences. When restricted to high-O3 days (highest 3 peak O3 days per day of week per site per year), the 1-hr and 8-hr Sunday O3 mixing ratios were 11% and 10% lower, respectively, than their mean peak levels on Wednesdays (median of 14 site differences), with 6 of 14 sites showing statistically significant Wednesday-to-Sunday differences. The analyses of week-day/weekend differences in O3 precursor concentrations show that different emission reductions than normally take place each weekend will be required to achieve major reductions in ambient ozone levels in the Atlanta area.

A Dramatic Daytime Decrease in Water Vapor over Coastal Thailand

A remarkable decrease in water vapor was observed during daytime on calm days over coastal Thailand. Precipitable water vapor (PWV) and surface specific humidity (SSH) decreased by about 5 mm and 3 g kg -1, respectively, in Bangkok from the late morning to the late afternoon on sunny days with weak low-level winds between March 1998 and December 1999. A daytime moisture decrease occurs in the lower atmosphere over coastal areas near the Gulf of Thailand, where the sea breeze often prevails. The sea breeze is relatively strong near the northern gulf. Wind profile observed over Bangkok revealed strong descending flow in the lower atmosphere during daytime, suggesting divergence of the sea-breeze circulation. This descending flow explains the decrease in daytime moisture over coastal areas.A numerical experiment assuming calm conditions successfully simulated the daytime decrease in water vapor around Bangkok. The most remarkable drying associated with descending flow was simulated around the northern edge of the Bight of Bangkok, where the coastline is sheltered by inland areas. The shape of the coastline and the topography enhanced the sea-breeze circulation around Bangkok. In another model run assuming wet soil conditions, the diurnal range of water vapor was smaller than that simulated by the control run. Clear diurnal variation was observed on calm days, especially under dry soil moisture conditions. A large diurnal range in PWV tended to appear before the monsoon onset when the low-level wind was weak and the soil moisture was dry.

Daily feeding rhythm and rations of Pacific salmon of the genus Oncorhynchus in the period of marine prespawning migrations

The daily feeding rhythm and rations of the humpback salmon Oncorhynchus gorbuscha, the sockeyed salmon O. nerka, and the chum salmon O. keta during marine prespawning migrations is investigated with consideration of materials collected at daily stations in waters off eastern Kamchatka in June–July 1999 and 2001 (from catches of drift nets). The bulk of humpback salmon and sockeyed salmon food consists of euphausiids, hyperiids, large copepods, pteropods, and fish juveniles. In the food of chum salmon, pteropods dominated. In a 24-h period, salmon manifest a pronounced evening peak of stomach fullness, while at night feeding discontinues. Samples collected in the morning consisted of fish who had just started feeding after the night pause. In addition to nightly period of rest, all species manifested a daytime decrease in foraging activity, though less pronounced than in the night. The daily rhythm of Pacific salmons’s feeding depends on the vertical migrations of their food items (representatives of sound-scattering layers). During the marine feeding period, the most intensive feeding is recorded in the humpback salmon and chum salmon. The daily ration of the humpback salmon is lower than that of the chum salmon but includes animals of higher food value. Due to a high digestion rate in combination with a large stomach volume, the chum salmon can consume a large quantity of low-calorific food in a short time. The daily ration of the sockeyed salmon is considerably lower than that of other salmon species.

ASSESSMENT OF RILMENIDINE EFFICIENCY IN PATIENTS WITH ARTERIAL HYPERTENSION WITH DETERIORATION OF DAILY PROFILE OF BLOOD PRESSURE

Aim. To estimate an efficiency and tolerability of rilmenidine in hypertensive patients with different types of blood pressure (BP) daily profile – dipper and non-dipper. Methods. 23 patients with essential hypertension (EH), I-II stages, were included into the study. They were treated with rilmeneidine 1 mg daily during one month. Ambulatory BP monitoring (ABPM) and office BP measurements were made before and after the treatment. Based on ABPM results all patients were divided into two groups: with adequate decrease of BP at nighttime (dipper, D), and with insufficient decrease of BP at night￾time (non-dipper, ND). Results. One month rilmenidine monotherapy resulted in BP normalization in 52% of patients. Decrease in 24-hour BP, daytime and nighttime BP, burden with BP and BP variability during daytime was observed in both groups. A distinction in rilmenidine influence on BP daily index was revealed: initially normal BP daily index didn’t change in D group, while initially decreased BP daily index increased in ND group. Rilmenidine reduced the speed of morning BP rise in patients of ND group. Conclusion. Results of the study testify efficiency and satisfactory tolerability of monotherapy with rilmenidine 1 mg daily in patients with EH of I-II stages. For patients with insufficient decrease in BP during nighttime rilmenidine provides normalization of BP daily profile intensifying BP night decrease and reducing the speed of morning BP rise.