<br><b>Background:</b> Chronic perineal pain (CPP)-mediated through ganglion impar produces complex symptoms causing functional impairment and chronic disabling persistent pain. Ganglion impar which is a solitary midline sympathetic ganglion receives afferent pain fibers from various pelvic organs mediates this type of nociception. A procedure such as ganglion impar block-neurolysis allows blockade of pain reception and mediation, providing effective pain relief. This study is aimed at analyzing the technical feasibility, safety, and efficacy of trans-sacrococcygeal ganglion impar neurolysis in patients with CPP at a rural territory care center. <b>Materials and Methods:</b> Twenty-six patients with CPP were prospectively evaluated for trans-sacrococcygeal ganglion impar neurolysis following good response to diagnostic block under fluoroscopy guidance. Numeric Pain Rating Scale (NPRS) score was observed at various time intervals. The number of attempts and procedural complications was also noted. <b>Results:</b> Out of 26 patients, 16 (62%) were of cancer origin and 10 (38%) cases of noncancer pain with a mean age of 53 and 34 years, respectively. The average NPRS score at 6 weeks in the cancer group was three, while the score was zero in noncancer group. NPRS score at presentation and at 8 weeks follow-up showed significant improvement in both groups. There was no more than a single attempt made to access ganglia through our approach. No procedural-related complications were found. <b>Conclusion:</b> Social burden of CPP, especially in the rural population, is neglected and may appear demanding both to patients and treating professionals. Transsacrococcygeal Ganglion impar block and neurolysis offer a safe, convenient day-care procedure without any significant complications. In cancerous origin of pain, neurolysis could be a good adjuvant.<br>
Read full abstract