Scopus Databases Research Articles

Bibliometric analysis of the scientific production of rheumatology departments in Spain during the 2013-2022 period.

Bibliometric studies of scientific production in Spanish Rheumatology are scarce. The aim of this study was to analyze the bibliographic production of Rheumatology Services in Spain over the period 2013-2022. Original articles and reviews with the affiliation of the first or corresponding author to a Spanish rheumatology Service/Department/Section/Unit were identified in the Web of Science Core Collection and Scopus databases. Keywords and titles were used to classify articles by field (clinical, epidemiological or basic) and pathology. International collaborations and collaborations between Autonomous Communities (AC) were identified. Quantitative bibliometric indicators were obtained (number of articles published per year, pathology and AC) and impact indicators were obtained (based on the number of citations per article). The H-index was also calculated. The total number of publications was 2321, with an annual growth rate of 4.1% in the period analyzed. In 14.1% of the articles there were international collaborations, mainly with the United States and the United Kingdom, while between ACs the most numerous were between Madrid and Catalonia. The pathologies with the highest H-index were rheumatoid arthritis (RA), spondyloarthropathies (SpA), osteoarthritis and vasculitis (34, 32, 28 and 26, respectively). The H-index for the Spanish rheumatology services as a whole was 69. The scientific production of rheumatology services/departments/sections/units in our country increased between 2013 and 2022. By pathology, the scientific production in RA and SpA stands out.

Global landscape of Vibrio parahaemolyticus research: a bibliometric analysis.

Vibrio parahaemolyticus poses a notable threat to marine ecosystems and can cause infections and disease outbreaks in seafood species, which can affect humans upon consumption. The global impacts of such infections and outbreaks on human and animal health led to a growing number of studies from various countries discussing the prevention, control, treatment, and overall implications of V. parahaemolyticus. Hence, this study aims to retrieve relevant studies on V. parahaemolyticus using a bibliometric analysis to understand current research status, trends, and hotspots regarding this bacteria. Relevant literature was searched across the Scopus database, and the data were subsequently analyzed using Biblioshiny software. In addition, a manual examination was conducted to identify the hosts of V. parahaemolyticus and diseases caused by the bacteria. Overall, 7,096 records were obtained from Scopus from 1963 to 2023. A bibliometric analysis identified 17,220 authors, with China emerging as the global leader. The analysis also highlighted significant keywords such as "Vibrio parahaemolyticus," "Litopenaeus vannamei," and "innate immunity," suggesting a focus on the impact of V. parahaemolyticus on L. vannamei, specifically emphasizing the shrimp's innate immune responses. Host-disease interaction network also uncovered 53 interactions between hosts and diseases involving L. vannamei or Penaeus vannamei as the primary host, with acute hepatopancreas necrosis disease (AHPND) emerging as the most prevalent among them. This study can enhance our understanding of infections caused by V. parahaemolyticus and contribute to the development of effective strategies for their prevention and management.

Emergency Department Crowding as Contributing Factor Related to Patient-Initiated Violence Against Nurses-A Literature Review.

To synthesise how ED crowding contributes to patient-initiated violence against emergency nurses. Framework synthesis. A systematic literature search was conducted in the PubMed, PsycINFO, CINAHL and Scopus databases, covering articles up to 21 March 2024. A total of 25 articles were reviewed, evaluating study quality using the Crowe Critical Appraisal Tool and employing a framework synthesis approach to chart and synthesise data. The review identifies key factors linking emergency department crowding to patient-initiated violence, focusing on crowding conditions, vulnerable populations and adverse outcomes. It emphasises the importance of multidimensional assessments, including input, throughput, output stages and staffing characteristics. Special attention is needed for patients with severe symptoms who are triaged into lower priority categories, as their perceptions of injustice and dissatisfaction may increase the risk of aggressive behaviour. However, limited information is available regarding the perspectives of patients' family members. Accurate assessments of emergency department crowding and a thorough understanding of cognitive and emotional changes in high-risk patients are essential to develop strategies to manage patient-initiated violence effectively. This review improves emergency nurses' understanding of the dynamics of patient-initiated violence in crowded emergency departments, equipping them with knowledge to better anticipate and respond to such incidents. It also offers insights that are crucial for enhancing nursing practices and ensuring workplace safety, thereby supporting the development of future emergency safety strategies. As this is a systematic review and framework synthesis, there was no direct patient or public involvement.

Physical therapy assistance in labor: A systematic review and meta-analysis.

Physical therapy assistance during labor may provide physical and emotional support to the expectant mother. Through specific techniques, physical therapists may help alleviate pain, improve mobility, and facilitate a safer and more comfortable delivery. To perform a systematic review of the literature to assess the potential benefits and risks of physical therapy assistance during labor. A search was conducted in the MEDLINE/PubMed, LILACS, PEDro, EMBASE, CINAHL, CENTRAL, Web of Science, and SCOPUS databases, with no restrictions on dates or language. The terms "Physical therapy assistance" and "Labor" were used. Randomized and quasi-randomized clinical trials comparing a group receiving physical therapy assistance during labor with a control group receiving standard care were included. The Cochrane tool (RoB 2.0) was used to assess the Risk of Bias, and the certainty of evidence was evaluated using the GRADE system. Quantitative analysis was performed through meta-analyses. Twelve studies involving 984 pregnant women were included. There was an increase frequency of vaginal deliveries (RR: 1.10, 95% CI 1.04, 1.17; 9 studies; I2, 2%; T2, 0.00; p = 0.42) and a reduction in cesarean sections (RR: 0.52, 95% CI 0.35, 0.76; 9 studies; I2, 0%; T2, 0.00; p = 0.65) for the physical therapy group, findings based on high-certainty evidence. There was also a reduction in the duration of the first stage of labor (MD: -99.01 min, 95% CI -153.35, -44.66; 7 studies; I2, 88%; T2, 4546.40; p = 0.00001), duration of the second stage (MD: - 11.29 min, 95% CI -18.94, -3.64; 6 studies; I2, 53%; T2, 45.01; p = 0.06) and frequence of perineal lacerations (RR: 0.49, 95% CI 0.25, 0.96; 4 studies; I2, 0%; T2, 0.00; p = 0.70) for the intervention group, findings based on moderate-certainty evidence. There was also a reduction in pain by 1.46 points on the Visual Analog Scale (MD: -1.46, 95% CI -2.52, -0.41; 7 studies; I2, 100%; T2, 1.90; p < 0.00001), findings based on low-certainty evidence, a decrease in analgesic use (RR: 0.90, 95% CI 0.83, 0.99; 2 studies; I2, 0%; T2, 0.00; p = 0.44), and maternal anxiety by 7.65 points on the State-Trait Anxiety Inventory (MD: -7.65, 95% CI -11.27, -4.03; 2 studies; I2, 88%; T2, 5.99; p = 0.005) for the intervention group. There was no difference in the other maternal and fetal outcomes. Physical therapy assistance during labor provides a number of benefits to the mother.

Bridging the Gap: A Systematic Review with Expert Opinion on the Use of Dalbavancin for In-Label and Off-Label Indications in Pediatric Patients

Objectives: The aim of this work was to perform a systematic review assessing the pharmacokinetic/pharmacodynamic (PK/PD) properties of dalbavancin and the clinical use for in-label and off-label indications in pediatric patients. Methods: Two authors independently searched the PubMed-MEDLINE and Scopus databases and clinicaltrials.gov up to 20 November 2024, to retrieve randomized controlled trials (RCTs), observational studies, PK studies, and case series/reports assessing dalbavancin PK/PD properties or the clinical use for both in-label and off-label indications in pediatric patients. Data were independently extracted by the two authors, and the quality of the included studies was independently assessed by means of specific tools according to study design. Clinical success was selected as the primary outcome. Descriptive statistics were used for summarizing the retrieved data. Subgroup analysis according to PK/PD data, as well as in-label and off-label indications, was performed. Results: After screening 206 articles, nine studies were included in the systematic review (one RCT, three PK studies, and five case series/reports; n = 267). Dalbavancin exposure was 30% lower in pediatric patients compared to adults. In acute bacterial skin and skin structure infections (ABSSSIs), the overall clinical success of dalbavancin was 96.1-97.3% and 92.9% in RCT and case series, respectively. Bone and joint infections (60.7%) and central-line-associated bloodstream infections (14.3%) represented the most common dalbavancin off-label indications in pediatric patients. Overall, the clinical success for off-label indications was 92.9%. The rate of adverse events ranged from 7.1% to 10.7%. Conclusions: Our systematic review summarized evidence concerning the PK/PD properties of dalbavancin and its use for in-label or off-label indications in pediatric patients. The available findings suggest that dalbavancin may be a valuable alternative for the management of ABSSSIs and/or off-label indications in pediatric patients according to efficacy and safety data, allowing for a potential minimized duration of hospital stay.

Programmed Cell Death Tunes Periodontitis.

To review current knowledge of the various processes of programmed cell death and their roles in immunoregulation in periodontitis. Relevant literature in the PubMed, Medline, and Scopus databases was searched, and a narrative review was performed. Programmed cell death and the regulation of its various pathways implicated in periodontal infection were reviewed. Multicellular organisms dispose of unnecessary or damaged cells via programmed cell death. Programmed cell death lies at the core of the balance of cell death and survival in pathological progress and infection. Periodontitis is a complex infectious disease involving virulence factors of periodontal pathogens and tightly regulated immune responses of the host. Different types of programmed cell death can play opposite roles in periodontitis or exert their action combinatorially. The coordinated system of various programmed cell death pathways and the extensive crosstalk among them play a fundamental role in the pathophysiology of periodontitis. Illuminating the precise roles and mechanisms of programmed cell death in periodontitis could open up novel therapeutic approaches.

The Ethical Role of Generative Artificial Intelligence in Modern HR Decision-Making: A Systematic Literature Review

The rapid development of generative artificial intelligence (AI) has led to the recognition of tools like ChatGPT and its potential to transform human resource (HR) management processes, particularly in decision-making. This review study aims to assess the effectiveness and benefits of ChatGPT in enhancing HR functions, particularly decision-making, and to identify any challenges and ethical considerations involved. Additionally, the study seeks to establish a hybrid framework that combines AI-driven decision-making with human oversight. A systematic literature review was conducted using PRISMA guidelines, selecting 50 articles from Scopus and Google Scholar databases. The literature review includes a synthesis analysis to assess publication trends and a keyword analysis to identify key themes such as ChatGPT’s impact on decision-making in HR management. The study reveals that ChatGPT can streamline HR processes, improve communication, and support personalized learning and decision-making, eventually contributing to enhanced performance and engagement. However, the technology requires human input for moral judgment and empathy, presenting challenges like resistance to adoption, algorithmic bias, and data privacy concerns. This study uniquely contributes to the literature by providing a systematic analysis of ChatGPT’s role in HR decision-making and proposing a hybrid framework that addresses AI’s limitations through ethical guidelines and human oversight. The findings emphasize the need for empirical research in larger, diverse settings and future enhancements to ChatGPT’s contextual understanding of HR.

The use of the ChatGPT AI tool in the training of pharmaceutical personnel

Aim of the study. To study the prospects for using the ChatGPT tool with artificial intelligence in the training of pharmaceutical workers.Materials and methods. A review of the literature on the topic of the article in the Scopus and RSCI databases for the period from 2020 to 2024 was conducted, and the materials of the results of using the ChatGPT artificial intelligence tool (versions 3.5 and 4.0) in the educational process of student pharmacists were analyzed.Results and discussion. The article discusses the experience of using the ChatGPT chatbot artificial intelligence tool by foreign scientists in the pharmaceutical field, both in various aspects of life and in educational and professional activities. The prospects for using the ChatGPT AI tool in the educational process in the training of pharmaceutical personnel at the School of Pharmacy of the Karaganda Medical University were studied. As a result of the analysis, both the positive aspects and risks of using ChatGPT in pedagogical activities were discussed.Conclusions. The obtained data indicate that the possibilities of using AI ChatGPT in society are not limited to entertainment purposes only. They also include educational purposes and provide opportunities for selfdevelopment and self-learning through interaction with the chatbot.

Major clinical outcomes of the endodontic infections and gut microbiota axis: a systematic review

Introduction: Endodontic therapy aims to shape, clean, and disinfect the root canal, and is performed by removing all pulp tissue or necrotic remains and microorganisms present in the root canal system. The gut microbiota or specific microbial metabolites not only locally influence the host's inflammatory responses, nutritional intake, or intestinal barrier function, but are also related to the immune and metabolic systems. In addition to antimicrobial activity, calcium hydroxide has properties such as dissolution of organic remnants, anti-inflammatory action, inhibition of inflammatory resorptions, and physical barrier function. Objective: To present the main considerations and clinical outcomes of the relationship between gut microbiota and endodontic infections and highlight endodontic treatment with calcium hydroxide, showing the mechanisms of antibacterial action. Methods: The PRISMA Platform systematic review rules were followed. The search was conducted from September to October 2024 in the Scopus, PubMed, Science Direct, Scielo, and Google Scholar databases. The quality of the studies was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument. Results and Conclusion: 102 articles were found, 25 were evaluated in full and 09 were included and developed in the present systematic review study. Considering the Cochrane tool for risk of bias, the overall assessment resulted in 35 studies with a high risk of bias and 22 studies that did not meet GRADE and AMSTAR-2. Most studies did not show homogeneity in their results, with X2=79.2%&lt;50%. It was concluded that, in the setting of endodontic therapy, the presence of microorganisms, particularly gramnegative anaerobes, in the root canal system and cementum resorption gaps after root canal treatment is considered one of the main causes of persistent periapical lesions and, therefore, of endodontic treatment failure. The gut microbiota or specific microbial metabolites not only locally influence the patient's inflammatory responses, nutritional intake, or intestinal barrier function, but are also related to the immune and metabolic systems. The change in the microbiota of the oral-gut axis and its interactions with Helicobacter pylori may be potential targets for the diagnosis and infectious treatment of Helicobacter pylori. Calcium hydroxide in endodontics is the most widely used medication to combat pathology-causing bacteria, but when used alone it may not be able to eliminate these microorganisms. The combination of other medications incorporated into calcium hydroxide contributes to positive results with the elimination of more resistant bacteria.

Effects of Physical Exercise on Chemotherapy-Induced Peripheral Neuropathy: A Systematic Review and Meta-Analysis.

The aim of this systematic review and meta-analysis is to systematically collect, evaluate, and critically synthesize research findings on the effects of physical exercise on chemotherapy-induced peripheral neuropathy (CIPN). The Joanna Briggs Institute (JBI) methodology for systematic reviews was adopted for this study. We searched the Medline®, CINAHL, SportDiscus, and Scopus databases to identify relevant articles published from inception to March 2024. This review was reported in accordance with the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Twelve studies met the inclusion criteria, totaling 928 participants. Interventions ranged from aerobic and resistance exercises to balance and strength training. A range of physical exercise interventions was explored, including brisk walking, endurance training, weight exercises, and resistance bands, as well as combined programs of aerobics, resistance, and balance training, all tailored to improve symptoms and quality of life in patients with chemotherapy-induced peripheral neuropathy. The meta-analysis focused on five studies that used the FACT/GOG-Ntx scale indicated a standardized mean difference of 0.50 (95% CI: 0.26, 0.74), favoring exercise, reflecting significant improvements in neuropathy symptoms. The heterogeneity among the studies was low (I² = 2%), suggesting consistency in the beneficial effects of exercise. From the results analyzed, the descriptive analysis of the 12 included studies shows promising outcomes not only related to individuals' perceptions of CIPN severity but also in terms of physical functioning, balance, ADL (Activities of Daily Living) performance, pain, and quality of life. The findings support the integration of structured exercise programs into oncological treatment plans.

Mapping the field of workplace deviant behavior: a comprehensive bibliometric analysis

Purpose This study aims to conduct a rigorous bibliometric analysis of workplace deviant behavior (WDB) to identify prevailing trends, patterns, and themes in the field. The analysis seeks to outline the domain’s intellectual and social structure and provide a research roadmap. Design/methodology/approach The study employed a systematic procedure to scrutinize research scenario. A search in the Scopus database produced 1,677 papers from reputable publications spanning 42 years (1976–2023). Science mapping techniques, including co-citation, co-authorship, and co-occurrence analysis, were used to obtain insights into the research landscape. By implementing these techniques, the authors comprehensively understood the interconnectedness and patterns within the research field. Findings This study demonstrates an apparent surge in the overall number and impact of studies conducted on WDB, most of which are published in prestigious publications. Furthermore, the findings support Bradford’s law, defying Lotka’s law in this field. Through co-citation analysis, four clusters were identified in this area. Subsequently, co-occurrence was used to pinpoint several strong themes. Finally, the authors of the USA and China demonstrated the most significant collaboration. Originality/value This study is a pioneering approach to applying bibliometric analysis to explore WDB research; it addresses a gap in the comprehensive review of earlier research and contributes to enriching the body of knowledge in this area. The results of this research are helpful for practitioners, scholars and future researchers in this subject, even if it has its roots in scientometrics.

Gambling Disorder in Parkinson’s Disease: A Scoping Review on the Challenge of Rehabilitation Strategies

Background: Pathological gambling (PG) is a significant non-motor complication in Parkinson’s disease (PD), often linked to dopaminergic therapies. PG impacts the quality of life of patients and their families, presenting unique challenges due to its interplay with motor symptoms and cognitive impairments in PD. This scoping review synthesized current evidence on rehabilitation strategies for PG in PD. Methods: A systematic review was conducted across the PubMed, Web of Science, Embase, and Scopus databases to identify studies addressing pharmacological, psychological, and neuromodulatory approaches. The scoping objective was to map the available evidence on treatment strategies and identify research gaps. Results: Of 537 studies, 5 met the inclusion criteria. Pharmacological strategies included dopamine agonist adjustments, naltrexone, and amantadine, which showed partial efficacy but were often limited by significant side effects. Neuromodulation via deep brain stimulation (DBS) demonstrated potential by modulating limbic circuits, though risks like apathy and transient symptom exacerbation were noted. Psychological interventions, particularly cognitive-behavioral therapy (CBT), were the most effective in modifying gambling behaviors, though adaptations are needed for PD-specific cognitive and psychiatric challenges. Conclusions: Effective rehabilitation for PG in PD requires a multidisciplinary approach to balance motor symptom management with impulse control disorders. While pharmacological, psychological, and neuromodulatory interventions show promise, gaps remain regarding their long-term efficacy, combined use, and tailoring to PD-specific needs. The lack of large-scale, comparative studies and limited exploration of novel therapeutic combinations underscore the need for further research to optimize patient outcomes and develop comprehensive treatment frameworks.

Prevalence of metabolic syndrome among pregnant women: a systematic review and meta-analysis.

Metabolic syndrome (MetS) is a cluster of risk factors that increase the risk of cardiometabolic diseases. The prevalence of MetS and individual components across pregnancy has not been reviewed in the literature. This research was conducted to identify the prevalence of MetS and its components among pregnant women. The PubMed, EMBASE, CINAHL, Web of Science and Scopus databases were searched. The review protocol is registered in PROSPERO (CRD42023460729). Quality assessment was performed using the JBI critical appraisal checklist. The study selection, data extraction and data analyses were performed in accordance with the MOOSE guidelines. The prevalence of MetS among pregnant women was 16.3%, (n = 3946). The prevalences for individual MetS components were: low HDL, 12.3% (n = 1108); high fasting glucose, 16.2% (n = 2333); high triglycerides, 48.5% (n = 2880); obesity, 42.7% (n = 5162) and high blood pressure 37.7% (n = 828). According to the definitions used to diagnose MetS, the prevalences were 18.2% according to the World Health Organization, 15.0% according to the International Diabetes Federation and 17.2% according to the National Cholesterol Education Program Adult Treatment Panel III. When stratified by gestational age at assessment, the prevalence of MetS was 9.9% before 16 weeks' and 24.1% after 20 weeks' of gestation. This review demonstrates that MetS is detected in approximately one-fifth of pregnant women. Screening for MetS and its components during pregnancy may help identify young women at risk for future cardiovascular disease.

P0472 Artificial intelligence-enabled histology is comparable in performance to pathologists in assessing histological remission in inflammatory bowel disease: a systematic review, meta-analysis and meta-regression

Abstract Background Achieving histological remission is a desirable treatment target in inflammatory bowel disease (IBD)1, yet its assessment is challenged by high inter- and intra-observer variability, reliance on experts, and lack of standardisation2. Artificial intelligence (AI) holds promise in addressing these issues3. This systematic review, meta-analysis, and meta-regression evaluated the AI’s performance in assessing histological remission and compared it with that of pathologists. Methods We searched Medline/PubMed and Scopus databases from inception to September 2024. We included studies on AI models assessing histological activity in IBD, with or without comparison to pathologists. Pooled performance metrics were calculated: sensitivity, specificity, positive and negative predictive value (PPV &amp; NPV), observed agreement, and F1 score. A pairwise meta-analysis compared AI and pathologists, while sub-meta-analysis and meta-regression evaluated heterogeneity and factors influencing AI performance. Results From 432 studies retrieved, fourteen met the inclusion criteria. AI models exhibited strong performance with a pooled 0.85 sensitivity (95% CI 0.81-0.89), 0.88 specificity (0.85-0.91), 0.88 PPV (0.86-0.91), 0.83 NPV (0.76-0.89), 0.86 observed agreement (0.83-0.89), and 0.85 F1 score (0.82-0.88). AI demonstrated no significant differences when compared to pathologists’ PPV, observed agreement, and F1 score, but significantly lower sensitivity (OR 0.50, 95% CI 0.28-0.87; p=0.01) despite considerable heterogeneity (I2=0-74.6%). AI models for the adult population were linked to reduced heterogeneity and enhanced AI performance at meta-regression. Conclusion AI shows significant potential for assessing histological remission in IBD and performs comparably to pathologists. Future research should focus on standardised, large-scale studies to minimise heterogeneity and support widespread AI implementation in clinical practice.

Investigating the research landscape of chlorinated paraffins over the past ten decades.

Chlorinated paraffins (CPs) are classified as emerging persistent organic pollutants (POPs). Due to their associated environmental and health impacts, these groups of chemicals have been a subject of interest among researchers in the past decades. Here we used a scientometric approach to understand the research landscape of CPs using literature published in the Web of Science and Scopus database. RStudio and VOSviewer programs were employed as scientometric tools to analyze the publication trends in global CP-related research from 1916 to 2024. A total of 1,452 articles were published over this period, with a publication/author and co-author/publication ratio of 0.43 and 5.49, respectively. China ranked first in publication output (n = 556, 43.3%), and the highest total citations (n = 12,007), followed by Sweden (n = 90), Canada (n = 77), and Germany (n = 75). Publications from developing countries were limited, with most contributions from Africa originating from Egypt (n = 7), South Africa (n = 5), and Nigeria (n = 3), primarily through international collaborations. The average annual growth rate of 4.3% suggests a significant future article output. This scientometric analysis allowed us to infer global trends in CPs, identify tendencies and gaps, and contribute to future research. Despite having similar toxicity to short-chain chlorinated paraffin (SCCP), long-chain chlorinated paraffin (LCCP) has received less attention. Therefore, future research should prioritize studying LCCP bioaccumulation and toxicity in diverse food webs, focusing on aquatic species vulnerable to CPs and effective toxicological models. Additionally, collaborative research with developing countries should be encouraged to enhance meeting the Stockholm Convention's demand.

Strategies for the Diagnosis and Management of Osteomyelitis in Lower Limbs: A Literature Review

Objective This study aims to critically review the literature on diagnostic and therapeutic approaches to osteomyelitis in lower limbs, emphasizing the use of antibiotic-loaded cements, surgical advancements, and medicinal therapies. Methodology A systematic literature review was conducted using the PubMed and Scopus databases, covering the period from 2010 to 2024. The descriptors "osteomyelitis," "antibiotic cement," and "lower limb surgery" were combined using Boolean operators (AND, OR, and NOT) to maximize search precision. Initially, 50 articles were identified. After excluding duplicates and review studies, 40 titles and abstracts were screened. Of these, 30 studies were selected based on inclusion criteria, such as quantitative data on osteomyelitis management and adult populations. Extracted data were organized into tables and analyzed qualitatively and quantitatively to identify trends and patterns. Results The studies demonstrated that the use of antibiotic-loaded cements, combined with surgical debridement and systemic therapy, is highly effective in reducing infections and complications. Additionally, personalized approaches based on bacterial cultures significantly reduced recurrence rates. Conclusion Early interventions and the integration of innovative technologies are essential for the effective management of osteomyelitis in lower limbs.

Global research trends in necrotizing pancreatitis: a bibliometric analysis from 2013 to 2024.

This study aims to analyzing scientific publications related to necrotizing pancreatitis and its mortality, identifying key areas and trends, and determining the leading research institutions, authors, countries, and journals actively working in this field. The Web of Science and Scopus databases were searched for articles on NP published between January 1, 2013, and April 22, 2024. Articles published before 2013, conference abstracts, and case reports were excluded. The articles were assessed based on various metrics, including the number of citations, publication dates, countries of origin, institutions, journals, and authors. A total of 929 articles were identified, of which 251 were deemed suitable for analysis after duplicates were removed. China contributed the most articles, followed by the United States and India. The most frequent publications appeared in specialized journals such as "Pancreatology" and "Journal of Gastrointestinal Surgery." The primary research institutions were universities and medical centers. The highest-impact articles focused on minimally invasive treatment methods for NP. There has been a growing body of research in NP over the past decade, particularly in China and the United States. Despite advancements in medical science, the mortality rate associated with pancreatic necrosis remains high. This highlights the continued challenge in effectively addressing complications of acute pancreatitis. Researchers worldwide are actively exploring alternative therapeutic approaches to mitigate these complications and improve patient outcomes.

Factors Relating to Sprint Swimming Performance: A Systematic Review.

Swimming performance depends on a wide variety of factors; however, the interaction between these factors and their importance varies between events. In sprint events, the characterized pacing underlines its specific development, as swimmers must achieve the highest possible speed while sustaining it to the greatest extent possible. The aim of this review was to identify the key factors underlying sprint swimming performance and to provide in-depth and practical evidence-based information to optimize performance. The review protocol was not registered. PubMed, Web of Science and Scopus databases were searched up to October 31, 2023. Studies involving competitive swimmers and investigating sprint swimming performance were included, while studies conducted with young or masters' swimmers, triathletes or waterpolo players or not investigating sprint swimming performance were excluded. The Downs and Black Quality Assessment Checklist was performed on the included articles to assess the methodological quality. After applying the PICOS framework, 39 of the 1330 articles initially identified were included according to the PRISMA guidelines. The included records focused mainly on dry-land strength and in-water forces of both upper and lower limbs. A wide range of kinematic variables were also examined, together with the importance of anthropometric and various physiological parameters. This review highlights the importance of developing muscular strength and effectively transferring it to performance in the water. The evidence suggests that muscular development should prioritize enhancing velocity and effective displacement, rather than merely increasing force and performance in loaded tests. However, further research is needed to confirm this. While in-water forces have been well studied, there is a notable lack of analysis regarding drag. The optimal balance between stroke rate and stroke length should be determined individually, with a primary focus on achieving a high stroke length from a high stroke rate. Although anthropometry may play an important role in performance, the interaction of these traits appears to be complex, suggesting that other factors may be more important in determining performance outcomes. From a physiological perspective, the results indicate that the lactate peak and rate of accumulation should be thoroughly developed. Notwithstanding, this review shows the lack of a solid body of knowledge on the importance of anaerobic and especially aerobic factors. Finally, the absence of a list of potential confounders, together with the lack of high-quality studies involving elite swimmers (level 1 and 2), complicates the interpretation of the results.

DOP093 ECCO Topical Review on predictive models for IBD disease course and treatment response

Abstract Background Inflammatory Bowel Disease (IBD) poses a clinical challenge due to its variable progression and treatment response. Despite the development of predictive models, their clinical application remains limited due to validation and methodological inconsistencies. This ECCO Topical Review examines existing predictive models, assesses their relevance, and discusses the barriers to their clinical implementation. Methods A panel formed by the European Crohn's and Colitis Organisation (ECCO), including gastroenterologists, surgeons, and methodologists, reviewed predictive models on IBD disease course and treatment response. Using the Medline, PubMed, EMBASE, and Scopus databases, they systematically identified relevant literature to evaluate clinical significance, performance, and barriers to clinical integration. Results The panel developed 21 statements on predictive models for IBD disease course and response, with supporting text. Predictive models for IBD disease course For ulcerative colitis (UC), models included clinical factors (e.g., age at diagnosis, male gender), biochemical markers (e.g., C-reactive protein [CRP], anemia), and treatment history. Crohn’s disease (CD) models incorporated disease characteristics like stricturing behavior, perianal disease, and imaging findings. Predictive models for treatment response UC models focused on severe flares and moderate-to-severe cases managed with biologics, with predictors like CRP, disease duration, and endoscopic severity. CD models emphasized predictors like body mass index, smoking status, and CRP levels. The utility of omics data remains inconsistent. Barriers to clinical implementation Models lacked generalizability across diverse populations and face barriers related to clinical integration, healthcare acceptance, regulatory factors, and economics. Methodological approaches Future models should use diverse datasets and adhere to TRIPOD guidelines (1). Validation through metrics like calibration and discrimination, as well as trials, will be essential for real-world effectiveness. Future directions Predictive models should identify treatment responders, aid in safe discontinuation, and support personalized strategies. Models need biomarkers that are cost-effective, reproducible, and adaptable to individual patient profiles. Conclusion Based on this ECCO Topical Review currently being finalized, predictive models for IBD hold promise, but challenges persist in clinical integration. Overcoming methodological issues, performing validation, improving biomarkers, and conducting impact studies are critical. Collaboration among researchers, clinicians, and regulators is pivotal to advance models that improve patient outcomes. References (1)Collins et al. Transparent reporting of a multivariable prediction model for individual prognosis or diagnosis (TRIPOD): the TRIPOD statement. The TRIPOD Group. Circulation 2015;131(2):211–9.

Nutritional Support in the Prevention and Treatment of Pressure Ulcers in Healthy Aging: A Systematic Review of Nursing Interventions in Community Care

Introduction: Pressure ulcers (PUs) represent a significant challenge in chronic care, particularly among the elderly with reduced mobility. They result in substantial socio-healthcare costs and negatively impact patients’ psychological well-being. Malnutrition is a key risk factor, hindering healing and increasing the risk of complications. As such, appropriate nutritional interventions are crucial for managing PUs. However, these interventions are often underestimated in clinical practice, underscoring the need for a more comprehensive approach to elder care and healthy aging. Objectives: The primary objective of this study was to identify the best scientific evidence on nutritional interventions implemented by nurses in community settings to prevent complications related to PUs. Additionally, qualitative and quantitative outcomes reported in the included studies were analyzed. Method: This systematic review was conducted following PRISMA international guidelines. Searches were performed in PubMed, Scopus, Embase, and CINAHL databases. A predefined search strategy using Boolean operators was employed, and two researchers independently selected papers, with a third researcher resolving any discrepancies. Additional sources and manual reviews were conducted to minimize selection bias. Results: Out of 1003 records, 6 studies were included. Findings indicate that nurses play a fundamental role in managing PUs in community settings through specific nutritional intervention assistance processes. These healthcare professionals are pivotal in the prevention, care, and rehabilitation of vulnerable individuals with PUs. Conclusions: Nurses are strategic in the management of PUs within community care for frail populations. With nutritional support that plays a key role in both preventing and accelerating the healing of PUs. Policymakers are encouraged to invest in nursing roles to enhance assistance in community contexts, supporting healthy aging and lifestyle medicine approaches.