The characteristics of water-based hybrid nanofluid flow when passing over an exponentially stretchable sheet with velocity and thermal slip factors are presented. This article provides a concept for a hybridized fluid comprising copper and cobalt iron oxide nanoparticles (NPs) dispersed into a base fluid (water). In addition, physical observations of the heat absorption behavior, the Darcy effect, the thermal radiation, and viscous dissipation are also taken into account. Because of their strong thermophysical properties, copper and cobalt iron oxide NPs are used in a wide range of applications in the engineering and medical fields. To study the dynamics of these NPs, a system of partial differential equations (PDEs) has been generated that forms a highly nonlinear coupled model. The PDE system is converted into nondimensional ordinary differential equations (ODEs) with the aid of similarity replacements. The semi-analytical homotopy analysis method (HAM) is applied to the set of dimensionless ODEs obtained to find the solution. Two engineering parameters, the Nusselt number and the skin friction, are plotted versus various parameters of the hybridized fluid using bar charts. It was observed that the no-slip condition, the suction parameter, and the Darcy–Forchheimer medium enhanced the thermal profile of the hybridized fluid.