Daily Caloric Intake Research Articles

Rural households' food security and its determinants in coastal regions of Bangladesh

AbstractThe coastal zone of Bangladesh is suffering from a wide range of climate change‐driven hazards. Limited attention has been given to these zones' food security assessment. Therefore, this study aims to assess the status of food security and its determinants among different groups of Bangladeshi coastal households. It also identifies their livelihood risks and coping strategies during stressed situations. Data were collected from 1350 households from coastal districts through a questionnaire survey. Food security was calculated and compared with the recommended average (2400 kcal/capita/day). A binary logit model was used to identify the determinants of food security among rural coastal households. Livelihood risks and coping mechanisms were recorded through open‐ended questions. The findings of this study revealed that although on average, sampled households were food secure (2753 kcal/capita/day), 81% of landless households and 72% of marginal landholders within the sample appeared food insecure. Among various food items, rice supplied the greatest total daily calorie intake (1841.47 kcal), second was the edible oil (172.27 kcal). The regression model revealed that farm size, farm income, off‐farm income, and crop production had positive impacts on households' food security. Floods, salinity, heavy rainfall, and reduction of land productivity were high risks to the large farm households, while heavy rainfall, floods, and salinity were high risks to the landless farm households. To cope with these risks, the majority of large farm households used their savings and sold livestock and poultry as coping strategies. The landless and marginal farmers were mostly helped by nongovernmental and government‐run organizations, moved elsewhere to find work, sold their labor, and were involved in fishing. It was concluded that different groups of farmers face different challenges. Our findings indicate that in order to protect landless and marginal farmers, government should implement policies aimed at increasing crop production by means of prioritizing saline‐tolerant crop varieties and the creation of more job opportunities.

Refeeding Syndrome and Its Related Factors in Critically Ill Coronavirus Disease 2019 Patients: A Prospective Cohort Study.

Background and AimMalnutrition and its complications is usually neglected in critically ill COVID-19 patients. We conducted the present study to investigate the prevalence of refeeding syndrome and its related factors in this group of patients.MethodsIn this prospective cohort study, 327 patients were assessed for being at risk and developing refeeding syndrome. The criteria was ASPEN consensus recommendations for refeeding syndrome released in 2020. Malnutrition was assessed based on global leadership initiative on malnutrition (GLIM) criteria. The relation between actual protein, calorie intake, and refeeding syndrome was also evaluated via cox regression model. The data concerning calorie and protein intake were gathered for 5 days after initiating feeding. The daily protein and calorie intake were divided by kilogram body weight in order to calculate the actual protein (g/kg/day) and energy (kcal/kg/day) intake.ResultsAmong the subjects, 268 (82%) were at risk of refeeding syndrome and 116 (36%) got involved in this syndrome. Malnutrition, according to the GLIM criteria, was found in 193 (59%) of the subjects. In the at-risk population, the risk of refeeding syndrome was reduced by 90% with the rise in protein intake (CI; 0.021–0.436, P = 0.002), increased by 1.04 times with the increase in age (CI; 1.032–1.067, P < 0.001), and by 1.19 times with the rise in the days from illness onset to admission (CI; 1.081–1.312, P < 0.001) in adjusted cox model analysis.ConclusionThe incidence of refeeding syndrome is relatively high, which threatens the majority of critically ill COVID-19 patients. Increased protein intake was found to reduce the occurrence of refeeding syndrome.

Pre-diagnosis lifestyle, health history and psychosocial factors associated with stage at breast cancer diagnosis – Potential targets to shift stage earlier

BackgroundEarly detection of breast cancer improves survival, so identifying factors associated with stage at diagnosis may help formulate cancer prevention messages tailored for higher risk women. The goal of this study was to evaluate associations between multiple potential risk factors, including novel ones, measured before a breast cancer diagnosis and stage at diagnosis in women from Alberta, Canada. MethodsWomen enrolled in Alberta’s Tomorrow Project completed health and lifestyle questionnaires on average 7 years before their breast cancer diagnosis. The association of previously identified and novel predictors with stage (I, II and III + IV) at diagnosis were simultaneously evaluated in partial proportional odds ordinal (PPO) regression models. ResultsThe 492 women in this study were predominantly diagnosed in Stage 1 (51.4%), had college or university education (75.4%), were married or had a partner (74.6%), had been pregnant (90.2%), had taken birth control pills for any reason (86.8%), and had an average body mass index of 26.6. Most had at least one mammogram (83%) with five mammograms the average number. Nearly all reported previously having a breast health examination from a medical practitioner (92.5%). Statistically significant factors identified in the PPO model included protective ones (older age at diagnosis, high household income, parity, smoking, spending time in the sun during high ultraviolet times, having a mammogram and high daily protein intake) and ones that increased risk of later stage at diagnosis (a comorbidity, current stressful situations and high daily caloric intake). ConclusionShifting breast cancer stage at diagnosis downwards may potentially be achieved through cancer prevention programs that target higher risk groups such as women with co-morbidities, non-smokers and younger women who may be eligible for breast cancer screening.

Extended Non-Fasting Period And Delayed Last Meal Are Associated With Peak Oxygen Consumption In Heart Failure With Preserved Ejection Fraction

<h3>Introduction</h3> Delayed time of eating last meal has been recently associated with favorable cardiorespiratory fitness (CRF) in patients with Heart Failure with preserved ejection fraction (HFpEF). However, whether the overall 24-hour non-fasting period is associated with CRF in these patients is unknown. The aim of this analysis was to examine associations between non-fasting period and CRF in HFpEF, and we hypothesized that a greater non-fasting period was associated with improved CRF, independent of daily caloric intake. <h3>Methods</h3> Twenty-one consecutive patients with HFpEF (left ventricular ejection fraction >50%) underwent maximal cardiopulmonary exercise testing to measure CRF, defined as peak oxygen consumption (VO₂) (ml•kg⁻¹•min⁻¹) and exercise time. A 5-pass, 24-hour dietary recall was administered to collect all timing of caloric intake. Daily non-fasting time was considered as the duration between the first and last meals. Dietary recall was analyzed with Nutrition Data Systems for Research Software to obtain total calories. The International Physical Activity Questionnaire was administered to collect self-reported physical activity. Spearman rank correlation and multiple linear regression was utilized to examine associations. Results are displayed as median (interquartile range; IQR). <h3>Results</h3> Patient characteristics are displayed in <b>Table 1</b>. On univariate analysis, daily non-fasting time was associated with peak VO₂ and exercise time (<b>Figure 1</b>). Time of last meal was also associated with peak VO₂ (r=0.571, <i>P</i>=0.007) and exercise time (r=0.528, <i>P</i>=0.014), however, time of first meal was not associated with peak VO₂ or exercise time (both <i>P</i>>0.6). On multivariate analysis, peak VO₂ remained associated with daily non-fasting time (<i>P</i>=0.041) and last meal time (<i>P</i>=0.022) when adjusted for total calories, physical activity, and age. <h3>Conclusion</h3> Extended daily non-fasting time and delayed last meal time are independently associated with more favorable CRF in patients with HFpEF. Prospective clinical trials to extend daily non-fasting window by delaying the final evening meal are warranted.

Arbuscular Mycorrhizal Symbiosis Differentially Affects the Nutritional Status of Two Durum Wheat Genotypes under Drought Conditions.

Durum wheat is one of the most important agricultural crops, currently providing 18% of the daily intake of calories and 20% of daily protein intake for humans. However, being wheat that is cultivated in arid and semiarid areas, its productivity is threatened by drought stress, which is being exacerbated by climate change. Therefore, the identification of drought tolerant wheat genotypes is critical for increasing grain yield and also improving the capability of crops to uptake and assimilate nutrients, which are seriously affected by drought. This work aimed to determine the effect of arbuscular mycorrhizal fungi (AMF) on plant growth under normal and limited water availability in two durum wheat genotypes (Svevo and Etrusco). Furthermore, we investigated how the plant nutritional status responds to drought stress. We found that the response of Svevo and Etrusco to drought stress was differentially affected by AMF. Interestingly, we revealed that AMF positively affected sulfur homeostasis under drought conditions, mainly in the Svevo cultivar. The results provide a valuable indication that the identification of drought tolerant plants cannot ignore their nutrient use efficiency or the impact of other biotic soil components (i.e., AMF).

Association between lifestyle factors and metabolic syndrome in general populations with depressive symptoms in cross-setional based cohort study of Ansung-Ansan.

BackgroundMetabolic syndrome (MetS) is caused by both genetic and environmental factors, such as daily calorie intake, smoking, and alcohol consumption. Lifestyle factors, such as alcohol consumption, are considered to be related to the prevalence of MetS and plays an essential role in the pathogenesis and prognosis of depression.MethodsWe investigated the bidirectional association between lifestyle factors and MetS among Korean adults with depressive symptoms in third wave of a community-based cohort study. A total of 1,578 individuals, aged 39–72 years, who had MetS at baseline were recruited. Participants were divided into two groups according to depressive symptoms. Logistic regression models were used to estimate the risk of MetS.ResultsThe percentage of heavy drinkers was lower in men with depressive symptoms compared to those who did not (7.0% vs. 7.1%), while the percentage of current smokers were higher in participants who had depressive symptoms (40.2% vs. 30.0%). After adjusting for age, education, monthly income, body mass index (BMI), sleep duration, and volume of drinking and smoking status, logistic regression analysis demonstrated that male heavy drinkers with depressive symptoms were 2.75 times more likely to have MetS than those without depressive symptom. Conversely, depressive women with a high BMI were 3.70 times more likely to have MetS than in those with lower BMI. Limitations The cross-sectional nature of the study, and the study population ethnicity and ages were limitations.ConclusionsLifestyle factors, such as alcohol consumption, may be associated with the risk of MetS in adults with depressive symptoms.

The consumption of micronutrients in relation to calorie intake and risk of insulin resistance

Background and aimsAdequate dietary intakes of essential micronutrients are critical to prevent insulin resistance (IR)-related diseases. Even though the excess calorie intake linked with obesity is also associated with such diseases, no previous studies evaluated the importance of meeting the Dietary Reference Intake (DRI) of micronutrients in relation to calorie intake in those at risk for developing IR. Methods and resultsWe evaluated the relationship between the ability or failure to meet the DRI of micronutrients in relation to daily calorie intake in 463 childbearing-age women with a higher prevalence of IR. 56–65% women met the DRIs for vitamin B12, vitamin C, thiamine, and riboflavin while only 0%–49% met the DRIs for folate, pyridoxine, niacin, pantothenic acid, total carotene, vitamins A, D and E by consuming an acceptable number of calories. Women who met the DRIs of folate and vitamin C within acceptable daily calorie intakes were 59% and 66% less likely to have higher Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) compared to women who did not. ConclusionsUnderstanding the mechanisms that explain our findings will be of value to address IR-associated with exposure to high calorie/low-micronutrient dense diets consumed by childbearing-age women. Since there is a global recognition that IR has been increasing in adults and children, similar studies of this nature in pregnant women at risk for IR will provide much needed data to assess the burden of such adverse dietary habits in the offspring. Our study approach may form the foundation for such studies.

Malnutrition by GLIM criteria in chronic pancreatitis: Prevalence, predictors, and its impact on quality of life

IntroductionMalnutrition in chronic pancreatitis (CP) has prognostic value and there is limited data on the prevalence, predictors of malnutrition in CP and its effect on Quality of life (QoL). MethodsA retrospective study was conducted in patients with CP to assess the prevalence of malnutrition as per the Global Leadership Initiative on Malnutrition (GLIM) criteria. Multivariable-adjusted regression was used to identify independent predictors of both malnutrition and global QoL. ResultsA total of 297 patients were included and the most common etiology of CP was idiopathic (75%) and alcohol (25%). The prevalence of malnutrition was 46.4% as per GLIM criteria. On univariate analysis, the risk of malnutrition was significantly higher in alcoholic etiology (p = 0.001), current alcohol consumption (p = 0.001), smokers (p < 0.001), those having higher cumulative days of pain in last 6 months (p < 0.001) and lower daily calorie intake (p = 0.019). On multivariate analysis, malnutrition was independently associated with current alcohol consumption (Odds ratio: 3.22, p = 0.017), current smokers (OR: 2.23, p = 0.042) and those having higher cumulative days of abdominal pain (OR: 1.01, p < 0.001), while higher daily calorie intake (per 100 kcal) (OR:0.94, p = 0.023) has reduced risk of malnutrition. Malnutrition (p = 0.015) and higher cumulative days of abdominal pain (p < 0.001) were independently associated with lower global QoL in patients with CP. ConclusionMalnutrition is frequent in patients with CP; and current alcohol consumption, smoking and higher cumulative days of abdominal pain independently predicts risk of developing malnutrition. Patients with malnutrition and higher cumulative days of pain has poorer quality of life.

A pilot randomized trial of simplified versus standard calorie dietary self-monitoring in a mobile weight loss intervention.

This study tested the efficacy of a lower-burden, simplified dietary self-monitoring approach compared with a standard calorie monitoring approach for self-monitoring adherence and weight loss in a mobile-delivered behavioral weight loss intervention. Participants (n = 72) with overweight or obesity who had children 2 to 12 years of age living in the home were randomly assigned to a group that used simplified dietary self-monitoring of high-calorie foods (Simplified) or a group that tracked calories (Standard). Both groups received a wireless scale, Fitbit trackers, and a 6-month intervention delivered via a smartphone application with lessons, text messages, and weekly personalized feedback messages. Percentage weight loss at 6 months was 5.7% (95% CI: -8.3% to -3.2%) in the Standard group and 4.0% (95% CI: -5.7% to -2.3%) in the Simplified group, which was not significantly different. Similar proportions reached 5% weight loss at 6 months (43.2% in Standard and 42.9% in Simplified). There were no differences in number of dietary tracking days or change in average daily caloric intake between groups. Two mobile-delivered weight loss interventions produced clinically meaningful levels of weight loss at 6 months, with no differences in dietary tracking adherence or dietary intake. The results suggest that simplified monitoring of high-calorie foods could be a promising alternative to calorie monitoring.

Inflammation Status and Body Composition Predict Two-Year Mortality of Patients with Locally Advanced Head and Neck Squamous Cell Carcinoma under Provision of Recommended Energy Intake during Concurrent Chemoradiotherapy.

Only few prospective cohort trials have evaluated the risk factors for the 2-year mortality rate between two patient subgroups with locally advanced head and neck squamous cell carcinoma (LAHNSCC): oral cavity cancer with adjuvant concurrent chemoradiotherapy (CCRT) (OCC) and non-oral cavity cancer with primary CCRT (NOCC), under the recommended calorie intake and investigated the interplay among calorie supply, nutrition–inflammation biomarkers (NIBs), and total body composition change (TBC), as assessed using dual-energy X-ray absorptiometry (DXA). Patients with LAHNSCC who consumed at least 25 kcal/kg/day during CCRT were prospectively recruited. Clinicopathological variables, blood NIBs, CCRT-related factors, and TBC data before and after treatment were collected. Factor analysis was performed to reduce the number of anthropometric and DXA-derived measurements. Cox proportional hazards models were used for analysis. We enrolled 123 patients with LAHNSCC (69 with OCC and 54 with NOCC). The mean daily calorie intake correlated with the treatment interval changes in total body muscle and fat. Patients consuming ≥30 kcal/kg/day had lower pretreatment levels but exhibited fewer treatment interval changes in anthropometric and DXA measurements than patients consuming <30 kcal/kg/day. In the multivariate analysis of the 2-year mortality rate, the prognostic influence of the recommended calorie intake could not be confirmed, but different risk factors (performance status, pretreatment platelet-to-lymphocyte ratio, and treatment interval body muscle changes in patients with OCC; age, pretreatment neutrophil-to-lymphocyte ratio, and body fat storage in patients with NOCC) showed independent effects. Therefore, the inflammation status and body composition, but not the recommended calorie supply, contribute to the 2-year mortality rate for patients with LAHNSCC receiving CCRT.

Dietary lapses are associated with meaningful elevations in daily caloric intake and added sugar consumption during a lifestyle modification intervention.

ObjectiveLapses from the dietary prescription in lifestyle modification interventions for overweight/obesity are common and impact weight loss outcomes. While it is expected that lapses influence weight via increased consumption, there are no studies that have evaluated how dietary lapses affect dietary intake during treatment. This study examined the association between daily lapses and daily energy and macronutrient intake during a lifestyle modification intervention.MethodsThis study used an intensive longitudinal design to observe participants throughout a 6‐month lifestyle modification intervention. Participants (n = 32) were adults with overweight/obesity (body mass index 25–50 kg/m2) and a diagnosed cardiovascular disease risk factor (e.g., hypertension) with a desire to lose weight. Participants underwent a gold‐standard individual in‐person lifestyle modification protocol consisting of 3 months of weekly sessions with 3 months of monthly sessions. Each participant's dietary prescription included a calorie target range that was based on their starting weight. Participants completed ecological momentary assessment (EMA; repeated daily smartphone surveys) every other week to self‐report on dietary lapses and telephone‐based 24‐h dietary recalls every 6 weeks.ResultsOn days with EMA and recalled intake (n = 210 days), linear mixed models demonstrated significant associations between daily lapse and higher total daily caloric intake (B = 139.20, p < 0.05), more daily grams of added sugar (B = 16.24, p < 0.001), and likelihood of exceeding the daily calorie goal (B = 0.89, p < 0.05). The associations between daily lapse and intake of all other daily macronutrients were non‐significant.ConclusionsThis study contributes to literature suggesting that dietary lapses pose a threat to weight loss success. Results indicate that reducing lapse frequency could reduce overall caloric intake and added sugar consumption.

LONG TERM OUTCOMES OF PARTIAL ENTERAL NUTRITION THERAPY IN CHILDREN WITH CROHN’S DISEASE

Abstract BACKGROUND Partial enteral nutritional therapy (PEN, defined as 80% of daily caloric intake from formula) has shown similar efficacy in inducing remission for pediatric Crohn’s Disease (CD) in comparison to exclusive enteral nutrition (EEN, defined as 100% of daily caloric intake from formula). Long-term outcomes of PEN are not well defined in the literature We aimed to study the long-term outcomes of PEN as defined by the number of patients still on maintenance PEN at 1 and 2 years after initiation. METHODS This was a retrospective cohort study using electronic medical record data at a large pediatric academic center. Patients diagnosed with CD between ages 7-19 years at PEN initiation with available follow-up data were included. Exclusion criteria were diagnoses of ulcerative colitis or indeterminate colitis, concomitant treatment with systemic steroids (prednisone (or equivalent) dose &amp;gt; 20 mg daily), biologics, or immunomodulators. Data collected included demographic and IBD characteristics as well as details of PEN therapy. We calculated the one and two-year PEN persistence rates and used Kaplan-Meier methods to produce survival curves of PEN persistence with adjustment for censoring. RESULTS Between 2009 and 2021, forty-nine participants met inclusion criteria (out of 114 assessed for inclusion). Participants were mostly white (n = 38, 77%), and male (n = 30, 61%). The mean age at CD diagnosis was 11.4 years (standard deviation, SD: 2.9 years) and the mean age at PEN initiation was 12.1 years (SD: 2.6 years). The most common reasons for PEN initiation were primary induction (n = 30, 61%), family/patient preference to avoid other medications (n = 26, 53%), and failure of primary medical therapy (n = 10, 20%). The most chosen formula type for PEN therapy was partially hydrolyzed formulas (n = 30, 61%), followed by standard formulas with whole intact proteins (n = 16, 33%). The one-year PEN persistence rate was 51% (26/49) and the two-year persistence rate was 25% (12/49) (table1). The median time on PEN was 1.3 years (IQR: 0.6 – 2.2 years) (Figure 1). The most common reasons for discontinuation were disease relapse/progression (n=32/41,78%) and treatment non-adherence (n =8/41, 20%). A small number of individuals discontinued due to formula intolerance (n = 3/41,7%). The most common medical therapies escalated to were infliximab (n =21/41, 51%), and adalimumab (n = 8/41, 20%) when PEN was discontinued. DISCUSSION Our study suggests that PEN therapy can be used as potential long-term treatment strategy for mild pediatric Crohn’s disease while avoiding corticosteroids and side-effects common with other IBD therapies. Secondary analysis is underway to understand predictors of response or failure to PEN therapy such as disease location/ distribution, type of formula, and the amount of calories from food vs. formula.

LONG TERM OUTCOMES OF PARTIAL ENTERAL NUTRITION THERAPY IN CHILDREN WITH CROHN’S DISEASE

Partial enteral nutritional therapy (PEN, defined as 80% of daily caloric intake from formula) has shown similar efficacy in inducing remission for pediatric Crohn’s Disease (CD) in comparison to exclusive enteral nutrition (EEN, defined as 100% of daily caloric intake from formula). Long-term outcomes of PEN are not well defined in the literature We aimed to study the long-term outcomes of PEN as defined by the number of patients still on maintenance PEN at 1 and 2 years after initiation.

Maternal Fructose Intake Causes Developmental Reprogramming of Hepatic Mitochondrial Catalytic Activity and Lipid Metabolism in Weanling and Young Adult Offspring.

Excess dietary fructose is a major public health concern, yet little is known about its influence on offspring development and later-life disease when consumed in excess during pregnancy. To determine whether increased maternal fructose intake could have long-term consequences on offspring health, we investigated the effects of 10% w/v fructose water intake during preconception and pregnancy in guinea pigs. Female Dunkin Hartley guinea pigs were fed a control diet (CD) or fructose diet (FD; providing 16% of total daily caloric intake) ad libitum 60 days prior to mating and throughout gestation. Dietary interventions ceased at day of delivery. Offspring were culled at day 21 (D21) (weaning) and at 4 months (4 M) (young adult). Fetal exposure to excess maternal fructose intake significantly increased male and female triglycerides at D21 and 4 M and circulating palmitoleic acid and total omega-7 through day 0 (D0) to 4 M. Proteomic and functional analysis of significantly differentially expressed proteins revealed that FD offspring (D21 and 4 M) had significantly increased mitochondrial metabolic activities of β-oxidation, electron transport chain (ETC) and oxidative phosphorylation and reactive oxygen species production compared to the CD offspring. Western blotting analysis of both FD offspring validated the increased protein abundances of mitochondrial ETC complex II and IV, SREBP-1c and FAS, whereas VDAC1 expression was higher at D21 but lower at 4 M. We provide evidence demonstrating offspring programmed hepatic mitochondrial metabolism and de novo lipogenesis following excess maternal fructose exposure. These underlying asymptomatic programmed pathways may lead to a predisposition to metabolic dysfunction later in life.

Self-management processes, sedentary behavior, physical activity and dietary self-management behaviors: impact on muscle outcomes in continuing care retirement community residents

BackgroundDespite the known benefits of non-sedentary behavior, physical activity, and protein and caloric intake to health and muscle mass, strength, and function, many older adults do not meet physical activity and dietary recommendations. A better understanding of the factors associated with sedentary behavior, physical activity and dietary self-management behaviors, and muscle outcomes (muscle mass, strength, and function) is needed, particularly among continuing care retirement community residents. The objective of this study was to examine the factors associated with sedentary behavior, physical activity and dietary self-management behaviors, and muscle outcomes among continuing care retirement community residents. It also aimed to determine whether sedentary behavior and physical activity and dietary self-management behaviors mediate the relationships between self-efficacy, goal congruence, aging expectations, social support, and muscle outcomes.MethodsA sample of 105 continuing care retirement community residents (age > 70 years) participated in this correlational, cross-sectional study. Questionnaires on pain, self-efficacy, goal congruence, aging expectation, social support, and daily protein and caloric intake were administered. Physical activity and sedentary behavior (ActiGraph wGT3X-BT), muscle mass (ImpediMed SFB7), muscle strength (Jamar Smart Digital Hand Dynamometer), and muscle function (Short Physical Performance Battery) were measured. Multiple regression, logistic regression, and mediation analyses were performed.ResultsLow goal congruence predicted engagement in sedentary behavior and light physical activity. Higher levels of self-efficacy and social support were associated with increased likelihoods of achieving greater moderate physical activity and meeting daily recommendations for caloric intake, respectively. Self-efficacy and goal congruence predicted muscle function and strength. Moreover, sedentary behavior and achieving greater moderate physical activity were found to partially but significantly mediate the relationship between self-efficacy and muscle function.ConclusionFuture research should evaluate whether attempts to reduce sedentary behavior and promote physical activity and dietary self-management behaviors and muscle outcomes are more successful when modifications to the self-management process factors are also targeted.

Comparison of the effects of different dietary regimens on susceptibility to experimental acute kidney injury: The roles of SIRT1 and TGF-β1

ObjectivesMortality due to acute kidney injury (AKI) is high despite its reversibility, and studies on efficient treatments for accelerating the recovery of or preventing AKI are of great significance. The amount of daily calorie intake and how it is taken affect body organs and how cells respond to it. The aim of this study was to determine the effects of four types of diets: calorie restriction (CR), time-restriction eating (TR), intermittent fasting (IF), and high-fat diet (HF), on renal injury indicators in male rats. MethodsAdult rats were placed on CR, TR, IF, and HF diets for 8 wk, after which AKI was induced in them by injection of glycerol. Renal injury indicators and biochemical parameters were measured before and after AKI induction. ResultsAfter AKI, urinary albumin excretion, urea, serum creatinine, and transforming growth factor (TGF)-β1 increased, whereas creatinine clearance and SIRT1 decreased. CR and TR diets improved renal indicators, decreased TGF-β1 and malondialdehyde (MDA), and increased SIRT1, total antioxidant capacity, and creatinine clearance after AKI induction. Although IF improved renal indicators, it only led to a decrease in MDA and TGF-β1. On the other hand, the HF diet worsened renal indicators, increased TGF-β1, and decreased SIRT1 in the kidney. Moreover, CR and TR improved metabolism indicators, and HF led to the abnormalization of these factors. ConclusionsThe results of the present study showed that CR and TR can be introduced as a treatment method to prevent AKI. These diets can increase the resistance of kidney cells against injuries, possibly by increasing SIRT1, decreasing TGF-β1, and improving antioxidant status; and they have renoprotective effects.

Analysis of the diet and food structure of the daily diet of children aged 3-17 years in the Russian Federation

A healthy diet is a necessary condition for the normal physical and mental development of children, which has a significant impact on the ability to withstand the effects of adverse environmental factors and determines the health of future generations. Healthy nutrition of children and adolescents is important not only for the normal physical and mental development of the child, but also as a factor determining the health of future generations. It is important for the preservation of the child's health to have a proper diet, that is, the distribution of the amount of food during the day (the multiplicity of meals), its energy value, chemical composition, food set for individual meals, a certain time of intake and the duration of intervals between meals. The aim of the study - to analyze the diet, nutrient and energy consumption and the structure of the food set of various meals in children aged 3-17 years. Material and methods. Analysis of the actual nutrition of about 18 000 children on the basis of primary materials obtained by the Federal State Statistics Service during the Selective observation of the diets of the population. Results. An analysis of nutrition of children aged 3-17 showed that the majority of children (67.9%) had three main meals with a hot meal (breakfast, lunch, dinner), while they accounted for the largest amounts of energy consumption in all age groups. Supplementary meals (evening snack and second breakfast) were characterized by the lowest calorie value, the afternoon snack occupied an intermediate position in terms of energy consumption. At the same time, energy consumption with the main meals as a % of the daily calorie intake did not correspond to the recommended values. A shift in energy consumption to the second half of the day, including just before bedtime, was revealed, especially in older children, which is a bad eating habit that can contribute to weight gain in a child. Bread products, cereals and cereal dishes made the greatest contribution to the daily calorie intake of children of all ages (32.4- 33.0%). Meat products occupied the second position in the share of daily calorie content (12.8-21.2%), dairy products provided 9.5-14.0% of daily energy, and among preschoolers their consumption, in contrast to meat products, was the highest, and among older schoolchildren - the lowest. An additional 8.3 to 14.9% of energy came from sugars found in non-dairy drinks, confectionery, chocolate, jams, and other sweets. Conclusion. An analysis of the diet and food structure of the daily ration of children aged 3-17 revealed deviations from the principles of healthy eating, especially in schoolchildren: energy consumption with the main meals did not meet the recommended norms, a significant proportion of the calorie intake fell on the second half of the day. Differences in the contribution of meals, as well as individual foods and dishes, to the total daily calorie value of diets in children, depending on age, have been established.

The impact of menu size on calorie estimation

Consumers seeking to maintain a healthy diet commonly estimate their daily caloric intake. Despite the importance of accurate calorie estimation, contextual and situational factors significantly influence consumers’ calorie estimations. The current research investigates how the number of items listed on a menu systematically influences consumers’ calorie estimations. Four experiments show that consumers estimate an item’s caloric content as greater (less) in a menu listing more (fewer) items. The results indicate that consumers are more likely to form a wider (vs. narrower) range of calorie estimates for a larger (vs. smaller) menu, leading them to estimate a target item’s caloric content as greater in a larger menu. We suggest that the number of menu items can prime a sense of magnitude, which in turn affects one’s calorie estimation process. • The paper investigates how the number of items listed on a menu influences consumers’ calorie estimations. • Consumers estimate an item’s caloric content as greater (less) in a menu listing more (fewer) items. • Consumers form a wider range of calorie estimates for a larger menu, leading them to higher caloric content of a target item. • The number of menu items primes a sense of magnitude, which in turn affects one’s calorie estimation process.

Abstract PO-188: The relationship of intervention attendance, changes in self-efficacy, social support, health behaviors, and weight loss outcomes among overweight Appalachian adults

Abstract Objectives: To determine whether self-efficacy and social support mediate the association between intervention attendance and changes in health behaviors; and to quantify the dose-response relationship between changes in health behaviors and weight loss outcomes. Methods: Data were from a group-randomized trial that compared a 1-year faith-based weight loss intervention to an active control group among overweight Appalachian adults in churches. Participants from the weight loss group who completed the 12-month assessment were included. Intervention attendance was defined as the percentage of sessions attended. Baseline and 12-month data on weight, self-efficacy for physical activity (SEPA), social support for eating healthy (SSEH), social support for physical activity (SSPA), exercise, and dietary intake were used. Mixed effect models were used to control for the random-effect of geographic regions. Results: Among the 243 included participants, most were female (76.2%), white (97.5%), and married or living with a partner (81.2%). After the 12-month intervention, participants lost 1.12±0.33kg weight, increased 0.44±0.13 servings/day of fruit and vegetable, reduced 321.55±41.99kcal/day of caloric intake, improved SSEH from family and friends, and increased SSPA from the church family (all P&amp;lt;0.05). Each 10% increase in intervention attendance was associated with higher odds of increased SSEH from family (OR=1.17, 95% CI=1.06-1.30) and friends (OR=1.16, 95% CI=1.04-1.28), and higher odds of increased SSPA from the church family (OR=1.27, 95% CI=1.12-1.44). SSPA from the church family mediated 96.7% of the association between intervention attendance and total exercise MET·min/week. Although intervention attendance was associated with increased walking MET·min/week, SEPA, SSPA from family/friends/church did not mediate the association. Additionally, with every 100 kcal decrease in caloric intake, weight and BMI decreased at 12-months (0.15±0.05kg, P=0.002; 0.058±0.017kg/m2, P=0.001). After adjusting for exercise, each 100 kcal decrease in caloric intake was associated with a decrease in weight and at 12-months (0.17±0.05kg, P=0.001; 0.065±0.019kg/m2, P=0.001). Conclusion: Social support from the church family plays an important role in increasing physical activity. There was a dose-response relationship between daily caloric intake and weight loss among Appalachian residents. Strategies to improve social support and reduce caloric intake are needed to improve the efficacy of weight loss through lifestyle modifications for this population. Citation Format: Xiaochen Zhang, Ryan D Baltic, Abigail Shoben, Electra D. Paskett. The relationship of intervention attendance, changes in self-efficacy, social support, health behaviors, and weight loss outcomes among overweight Appalachian adults [abstract]. In: Proceedings of the AACR Virtual Conference: 14th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2021 Oct 6-8. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2022;31(1 Suppl):Abstract nr PO-188.

A REVIEW ON EFFECT OF WEEDS IN WHEAT (TRITICUM AESTIVUM L.) AND THEIR MANAGEMENT PRACTICES

Wheat is the second most important cereal crop in the world. It has a vital role in the human diet globally, contributing to the daily calorie and protein intake than any other cereal crops. The productivity of wheat is low because of different biotic and abiotic factors. Weeds are one of the most important competitors of wheat crop. Understanding the nature of weeds is important to develop techniques to reduce their effects on the crops. Weeds, through competition with other crops, almost always have a deleterious effect on them and may be economically and environmentally detrimental. For world food sustainability controlling the weed-induced yield losses in the wheat is of prime importance because the weeds compete with the crop and also possess deleterious effects. There are various weed species that occur in the wheat crop field and they possess effects on the growth phases of wheat. Allelopathic effects of weeds on the germination, growth and yields on the crops are recorded. The variation in the vegetative traits such as the number of fertile tillers, spike length, grains/spike due to weeds is reflected ultimately in grain yield and quality. Both broad leaf weeds and narrow leaf weeds infest the wheat crop causing a 13.1% reduction in total grain yield globally. Although tillage operations and herbicides use have played an important role in weed control, but their indiscriminate use has resulted in unacceptable consequences on humans as well as vital ecosystems along with the evolution of herbicides resistance genotypes. Through a combination of integrated weed management approaches the crop competitiveness against the weed can be increased which results in the reduction of the weed-induced yield losses in wheat. The main purpose of this study is to review the competition of weeds in wheat crops as well as its effects on wheat growth and yield components. It also highlights the management strategies which could minimize the inhibitory effect of weeds on wheat crops.