Aim: To analyze the functional performance of patients with generalized scleroderma treated at the Department of Dermatology of the PIM of the Ministry of Internal Affairs and to develop recommendations for physiotherapists. Systemic sclerosis (SSc) is a chronic connective tissue disease characterized by progressive fibrosis of the skin and internal organs, the presence of microcirculatory disorders and the presence of autoantibodies. Materials and Methods: The study group consisted of 55 patients aged 27 years to 80 (mean 56.4) with systemic scleroderma, who receive rheological treatment in the Department of Dermatology on a cyclical basis. In addition, pharmacotherapy was supported by individually tailored rehabilitation for 2 years. Before and after the completed therapy, the results of the study were analyzed and recommendations were created for physiotherapists. Forty-two participated in the study. Results: All patients had mobility restrictions in the proximal and distal interphalangeal joints of both hands and in both temporomandibular joints. Conclusions: The study confirmed the need for guidelines for physiotherapists.