Custom Shapes Research Articles

A crowdsource based framework for Bengali scene text data collection and detection

Scene texts are the type of texts that we see in our surroundings when we are outside. They have custom fonts, sizes, shapes and colors that are often different from the fonts or styles typically found in documents. Scene text recognition has grown in popularity due to its significance in the development of smarter automated systems. Despite the fact that numerous types of research on scene text detection and recognition have been conducted in different languages, similar work on the Bengali language is limited by the lack of large-scale usable datasets. In this paper, we propose a multipurpose system for Bengali Scene text that allows for easy dataset collection via crowdsourcing as well as annotation, classification and detection tasks to be performed on the same platform. It comes with an Android-based application that can be used to capture or load images from the device, select Bengali texts over the images and annotate them. The images and labels are stored in the cloud. A Python-based script is used to perform real-time data processing, analysis, and detection tasks. The proposed system has also been tested on a crowdsourced Bengali scene text dataset collected by this system. The classification model achieved an accuracy score of 97%, and the detection model achieved a Mean Average Precision score of 92 on the on these crowd contributed dataset.

Thermal ablation with configurable shapes: a comprehensive, automated model for bespoke tumor treatment

BackgroundMalignant tumors routinely present with irregular shapes and complex configurations. The lack of customization to individual tumor shapes and standardization of procedures limits the success and application of thermal ablation.MethodsWe introduced an automated treatment model consisting of (i) trajectory and ablation profile planning, (ii) ablation probe insertion, (iii) dynamic energy delivery (including robotically driven control of the energy source power and location over time, according to a treatment plan bespoke to the tumor shape), and (iv) quantitative ablation margin verification. We used a microwave ablation system and a liver phantom (acrylamide polymer with a thermochromic ink) to mimic coagulation and measure the ablation volume. We estimated the ablation width as a function of power and velocity following a probabilistic model. Four representative shapes of liver tumors < 5 cm were selected from two publicly available databases. The ablated specimens were cut along the ablation probe axis and photographed. The shape of the ablated volume was extracted using a color-based segmentation method.ResultsThe uncertainty (standard deviation) of the ablation width increased with increasing power by ± 0.03 mm (95% credible interval [0.02, 0.043]) per watt increase in power and by ± 0.85 mm (95% credible interval [0, 2.5]) per mm/s increase in velocity. Continuous ablation along a straight-line trajectory resulted in elongated rotationally symmetric ablation shapes. Simultaneous regulation of the power and/or translation velocity allowed to modulate the ablation width at specific locations.ConclusionsThis study offers the proof-of-principle of the dynamic energy delivery system using ablation shapes from clinical cases of malignant liver tumors.Relevance statementThe proposed automated treatment model could favor the customization and standardization of thermal ablation for complex tumor shapes.Key points• Current thermal ablation systems are limited to ellipsoidal or spherical shapes.• Dynamic energy delivery produces elongated rotationally symmetric ablation shapes with varying widths.• For complex tumor shapes, multiple customized ablation shapes could be combined.Graphical

High temperature oxidation treated 3D printed anatomical WE43 alloy scaffolds for repairing periarticular bone defects: In vitro and in vivo studies

Reconstruction of subarticular bone defects is an intractable challenge in orthopedics. The simultaneous repair of cancellous defects, fractures, and cartilage damage is an ideal surgical outcome. 3D printed porous anatomical WE43 (magnesium with 4 wt% yttrium and 3 wt% rare earths) scaffolds have many advantages for repairing such bone defects, including good biocompatibility, appropriate mechanical strength, customizable shape and structure, and biodegradability. In a previous investigation, we successfully enhanced the corrosion resistance of WE43 samples via high temperature oxidation (HTO). In the present study, we explored the feasibility and effectiveness of HTO-treated 3D printed porous anatomical WE43 scaffolds for repairing the cancellous bone defects accompanied by split fractures via in vitro and in vivo experiments. After HTO treatment, a dense oxidation layer mainly composed of Y2O3 and Nd2O3 formed on the surface of scaffolds. In addition, the majority of the grains were equiaxed, with an average grain size of 7.4 μm. Cell and rabbit experiments confirmed the non-cytotoxicity and biocompatibility of the HTO-treated WE43 scaffolds. After the implantation of scaffolds inside bone defects, their porous structures could be maintained for more than 12 weeks without penetration and for more than 6 weeks with penetration. During the postoperative follow-up period for up to 48 weeks, radiographic examinations and histological analysis revealed that abundant bone gradually regenerated along with scaffold degradation, and stable osseointegration formed between new bone and scaffold residues. MRI images further demonstrated no evidence of any obvious damage to the cartilage, ligaments, or menisci, confirming the absence of traumatic osteoarthritis. Moreover, finite element analysis and biomechanical tests further verified that the scaffolds was conducive to a uniform mechanical distribution. In conclusion, applying the HTO-treated 3D printed porous anatomical WE43 scaffolds exhibited favorable repairing effects for subarticular cancellous bone defects, possessing great potential for clinical application.

In-mold electronics applications: the control of ink properties through the use of mixtures of electrically conductive pastes

Polymer thick films compatible with a thermoforming process are the key components to realize the next generation of human–machine interface and lighting with a 3D custom shape through an in-mold process. The purpose of this study is to demonstrate that a tailored combination of commercial pastes can offer the manufacturer more freedom in developing smart electronic devices. A four-point probe instrument was used to measure the resistivity of the printed circuit. We used the same formed printed sample to estimate the level of elongation under the thermoforming process due to the all-in-one screen design developed for the study. The important objective of this work was to form a paste which should withstand such operations without losing physical properties such as conductivity or adhesion or getting lines cracked.

Mechanical behaviour of reconstructed defected skull with custom PEEK implant and Titanium fixture plates under dynamic loading conditions using FEM

Skull reconstruction using cranial implants is often required for repairing skull defects caused due to trauma, diseases, or malignancy to protect intracranial structures. For relieving Intracranial Pressure (ICP) surgeons restore cranial defects either using natural bones or fabricated custom cranial implants. With the increase in Traumatic Brain Injuries (TBI) and challenges faced by TBI patients to regain normalcy, it is imperative to analyse the mechanical behaviour of skull-implant assemblies under some Head Injury Criteria (HIC). Medical grade materials including Titanium Alloys (Ti-6Al-4V) and Polyether-ether-ketone (PEEK) are used by fabricating Patient-Specific Implants (PSI) manufactured using 3D imaging, modelling and printing techniques. 3D technologies are preferred over conventional manufacturing methods, as they enable fabrication of custom shapes, sizes and properties for these PSI.For an effective attachment of PSI with a defective skull, a stable joint and plate arrangement as fixture plates is necessary at their interface. These fixtures can have variable numbers, design shapes, materials and location arrangements.This paper presents the Finite Element Method/Analysis (FEM/FEA) study of PSI attached to a defected skull for reconstruction, with linear shaped fixture configuration, when subjected to an external dynamic loading at 5 m/s, strain rate of 10s−1 to 243s−1 and ICP of 15mm Hg from three sides of the skull faces. Three different materials as Neoprene (soft), Concrete (medium rigid) and E-Glass (highly rigid) have been used, in the form of a rectangular thin cuboidal wall structure, at an angle of 45° with the skull face. Four linear shaped fixture plates which were simplest to design, were used to attach the PSI-skull assembly, to ensure that weight of the PSI-fixation assembly on the patient remains minimal, overall assembly has symmetrical fixations and efforts required by a surgeon for fitment of these plates remain minimal. Placement of these fixture plates has been optimized to encompass the complete PSI-skull interface section, due to which the stresses within all the assembly components (PSI, fixture plate and skull) reduced by nearly 2.5 times than the initial design and remained within yielding limits, thereby, averting any failure under heavy external dynamic loading.

Scintillation properties of Er3+-activated BaO–Nb2O5–TeO2 glasses

Recently, glasses have gained great interest for use as scintillators owing to lots of industrial benefits such as ease of producing customizable shapes and low production cost. Herein, the Er3+-activated BaO–Nb2O5–TeO2 glasses were fabricated for the development of NIR glass scintillators. The Er3+-activated BaO–Nb2O5–TeO2 glasses exhibited efficient photoluminescence and scintillation that originated from the 4f→4f transition of Er3+. Their quantum yields in photoluminescence were 80% (0.1%Er2O3), 81% (0.5%Er2O3), and 61% (1.0%Er2O3). Further, an almost linear correlation between an X-ray dose rate and NIR scintillation intensity was observed in the 0.5–5000 mGy h−1 dose rate range. Interestingly, the lowest detectable dose rate limit (0.5 mGy h−1) was lower than that of Er-doped Bi4Ge3O12 and Nd-doped GdVO4 single crystals. Further, afterglow levels of the non-doped and Er3+-activated BaO–Nb2O5–TeO2 glasses were about 600 ppm. The observed NIR scintillation properties indicated that the Er3+-activated tellurite glasses should be promising compounds for NIR-emitting scintillators.

Digital design and fabrication of clay formwork for concrete casting

This paper investigates the potential of clay extrusion as formwork for casting customized and building-scale fiber-reinforced concrete elements. Customizable shapes are produced using clay as cheap, sustainable, and easily demoldable formwork, extending its printable height limit. The coupled incremental clay 3D printing and concrete casting process allows the layered casts to start curing and reduces the hydrostatic pressure from concrete. The concluding case study, the Cocoon, demonstrates the method’s capability to achieve building-scale height, integrate openings, and create complex surfaces. The introduced method seeks to challenge techniques and materials for 3D-printed formworks, demonstrating the ability to reduce the environmental impacts of concrete construction without compromising the complexity and time efficiency of bespoke elements.

Highly resilient and fatigue-resistant poly(4-methyl-ε-caprolactone) porous scaffold fabricated via thiol-yne photo-crosslinking/salt-templating for soft tissue regeneration

Elastomeric scaffolds, individually customized to mimic the structural and mechanical properties of natural tissues have been used for tissue regeneration. In this regard, polyester elastic scaffolds with tunable mechanical properties and exceptional biological properties have been reported to provide mechanical support and structural integrity for tissue repair. Herein, poly(4-methyl-ε-caprolactone) (PMCL) was first double-terminated by alkynylation (PMCL-DY) as a liquid precursor at room temperature. Subsequently, three-dimensional porous scaffolds with custom shapes were fabricated from PMCL-DY via thiol-yne photocrosslinking using a practical salt template method. By manipulating the Mn of the precursor, the modulus of compression of the scaffold was easily adjusted. As evidenced by the complete recovery from 90% compression, the rapid recovery rate of >500 mm min−1, the extremely low energy loss coefficient of <0.1, and the superior fatigue resistance, the PMCL20-DY porous scaffold was confirmed to harbor excellent elastic properties. In addition, the high resilience of the scaffold was confirmed to endow it with a minimally invasive application potential. In vitro testing revealed that the 3D porous scaffold was biocompatible with rat bone marrow stromal cells (BMSCs), inducing BMSCs to differentiate into chondrogenic cells. In addition, the elastic porous scaffold demonstrated good regenerative efficiency in a 12-week rabbit cartilage defect model. Thus, the novel polyester scaffold with adaptable mechanical properties may have extensive applications in soft tissue regeneration.

All‐Inorganic Glass Scintillators: Scintillation Mechanism, Materials, and Applications

AbstractGlass scintillators have several benefits compared to the currently used single or polycrystalline scintillators, including non‐hygroscopicity, mechanical ruggedness, ease of producing customizable shapes, and low‐cost synthesis. The combination of the inert glass matrix and the embedded highly scintillating center render them significant materials for medical imaging and therapy, non‐destructive probing, nuclear monitoring, and high‐energy physics. Recently, great progress has been made in exploring new kinds of glass scintillator materials, improving imaging resolution for radiation detection, and developing an enormous range of commercial products. However, the majority of efforts have been devoted to the variation of materials, while rationally designing this new family of scintillators toward expected properties and applications is still lacking. In this review, the focus is specifically on advances in glass scintillators, including the scintillation fundamentals, material designing rule, and current application status, as well as future challenges and future directions.

Injectable 3D‐Printed Porous Scaffolds for Adipose Stem Cell Delivery and Endometrial Regeneration

AbstractStem‐cell‐based therapeutic strategies are promising in the clinical treatment of intrauterine adhesions (IUAs), while endometrial regeneration still hardly restores the structure and function of the endometrium because of the inadequate microenvironment for the grafted stem cells and subsequent limited therapeutic efficiency. Herein, an injectable porous hydrogel scaffold (PH scaffold) with customizable shapes is presented by using a microfluidic‐based 3D printing technique for adipose‐derived stem cells (ADSCs) delivery to enhance endometrial regeneration. These scaffolds display a controllable interconnected porous structure, which not only facilitates the encapsulation of ADSCs within the scaffold but also supports the recovery to their original shapes after injection. Furthermore, the cell viability of the laden ADSCs is well‐maintained post‐injection, exhibiting promotive effects on cell migration, proliferation, and tube formation. Based on these features, an ADSCs‐laden PH scaffold with a hollow endometrium‐mimicking morphology is designed and in situ injected into the damaged endometrium in rats of IUAs. These results show that the ADSCs‐laden PH scaffolds can enhance functional endometrial regeneration by suppressing the inflammatory response, promoting cell proliferation, and improving vascularization. Thus, it is believed that such unique 3D‐printed porous scaffolds are promising candidates for cell delivery, which also provides a minimally‐invasive and effective strategy for endometrial regeneration.

Programmable Shape Morphing Metasponge

Smart materials respond to environmental signals by changing their microstructure and physical properties. Programming multiple behaviors and functions into a single material could increase its utility and adaptability to ever‐changing environmental conditions. A swellable and stretchable metamaterial hydrogel or “metasponge” engineered to morph into customized sizes and shapes that dynamically tune its physical properties and functions is reported. Multiple case studies that take advantage of the morphing properties of the metasponge, including robotic actuation, light guidance, optical and sonic invisibility (“cloaking”), adaptation of propulsion mode, sampling, and multiple biomedical applications, are illustrated. Developing multifunctional smart materials in which logic is programmed into the materials rather than electronic components could pave a new path to autonomy and dynamic responses in soft robots, sensors, and actuators.

Detray: a compile time polymorphic tracking geometry description

A detailed geometry description is essential to any high quality track reconstruction application. In current C++ based track reconstruction software libraries this is often achieved by an object oriented, polymorphic geometry description that implements different shapes and objects by extending a common base class. Such a design, however, has been shown to be problematic when attempting to adapt these applications to run on heterogeneous computing hardware, particularly on hardware accelerators. We present detray, a compile time polymorphic and yet accurate track reconstruction geometry description which is part of the ACTS parallelization R&D effort. detray is built as an index based geometry description with a shallow memory layout, that uses variadic template programming to allow custom shapes and intersection algorithms rather than inheritance from abstract base classes. It is designed to serve as a potential geometry and navigation backend for ACTS and as such implements the ACTS navigation model of boundary portals and purely surface based geometric entities. detray is designed to work with a dedicated memory management library and thus can be instantiated as a geometry model in host and device code.

Optimization of Hexagonal Structure for Enhancing Heat Transfer in Storage System.

Thermal performance was tested during cycling work for latent heat storage systems based on KNO3 and NaNO3 (weight ratio 54:46). For heat transfer improvement, cast aluminum honeycomb-shaped structures were produced via 3D printing of polymer model and investment casting. Different wall thicknesses were tested at 1.2 mm and 1.6 mm. The obtained results were compared to working cycles of pure PCM bed. The use of enhancers is reported to improve the rate of charging and discharging of the deposit. In the next step, the structures were examined with numerical simulation performed with ANSYS Fluent software. The wall thicknesses taken into consideration were the following: 0.8, 1.2, 1.6, and 2.0 mm. An insert with a greater wall thickness allows for smaller dT/dt and better heat distribution in the vessel. The investment casting process enables the manufacturing of complex structures of custom shapes without porosity and contamination.

Highly elastic and self-healing nanostructured gelatin/clay colloidal gels with osteogenic capacity for minimally invasive and customized bone regeneration

Extrusible biomaterials have recently attracted increasing attention due to the desirable injectability and printability to allow minimally invasive administration and precise construction of tissue mimics. Specifically, self-healing colloidal gels are a novel class of candidate materials as injectables or printable inks considering their fascinating viscoelastic behavior and high degree of freedom on tailoring their compositional and mechanical properties. Herein, we developed a novel class of adaptable and osteogenic composite colloidal gels via electrostatic assembly of gelatin nanoparticles and nanoclay particles. These composite gels exhibited excellent injectability and printability, and remarkable mechanical properties reflected by the maximal elastic modulus reaching ∼150 kPa combined with high self-healing efficiency, outperforming most previously reported self-healing hydrogels. Moreover, the cytocompatibility and the osteogenic capacity of the colloidal gels were demonstrated by inductive culture of MC3T3 cells seeded on the three-dimensional (3D)-printed colloidal scaffolds. Besides, the biocompatibility and biodegradability of the colloidal gels was proved in vivo by subcutaneous implantation of the 3D-printed scaffolds. Furthermore, we investigated the therapeutic capacity of the colloidal gels, either in form of injectable gels or 3D-printed bone substitutes, using rat sinus bone augmentation model or critical-sized cranial defect model. The results confirmed that the composite gels were able to adapt to the local complexity including irregular or customized defect shapes and continuous on-site mechanical stimuli, but also to realize osteointegrity with the surrounding bone tissues and eventually be replaced by newly formed bones.

Buoyant magnetic milliswimmers reveal design rules for optimizing microswimmer performance.

Magnetically-actuated swimming microrobots are an emerging tool for navigating and manipulating materials in confined spaces. Recent work has demonstrated that it is possible to build such systems at the micro and nanoscales using polymer microspheres, magnetic particles and DNA nanotechnology. However, while these materials enable an unprecedented ability to build at small scales, such systems often demonstrate significant polydispersity resulting from both the material variations and the assembly process itself. This variability makes it difficult to predict, let alone optimize, the direction or magnitude of microswimmer velocity from design parameters such as link shape or aspect ratio. To isolate questions of a swimmer's design from variations in its physical dimensions, we present a novel experimental platform using two-photon polymerization to build a two-link, buoyant milliswimmer with a fully customizable shape and integrated flexible linker (the swimmer is underactuated, enabling asymmetric cyclic motion and net translation). Our approach enables us to control both swimming direction and repeatability of swimmer performance. These studies provide ground truth data revealing that neither the first order nor second order models currently capture the key features of milliswimmer performance. We therefore use our experimental platform to develop design guidelines for tuning the swimming speeds, and we identify the following three approaches for increasing speed: (1) tuning the actuation frequency for a fixed aspect ratio, (2) adjusting the aspect ratio given a desired range of operating frequencies, and (3) using the weaker value of linker stiffness from among the values that we tested, while still maintaining a robust connection between the links. We also find experimentally that spherical two-link swimmers with dissimilar link diameters achieve net velocities comparable to swimmers with cylindrical links, but that two-link spherical swimmers of equal diameter do not.

Direct Conversion of Liquid Organic Precursor into 3D Laser-Induced Graphene Materials.

Among the different states of matter, liquids have particular advantages in terms of easy handling and recycling, which has been manifested in various chemosynthetic reactions, but remains underexplored in graphene synthesis. This work reports the direct conversion of liquid organic precursor into versatile 3D graphene materials using rapid laser irradiation. The liquid precursor allows for easy fabrication of graphene with significant 3D architectures, including powders, patterned composite structures, and substrate-free films. Taking advantage of the high compatibility of liquid precursor with a wide range of dopants, the 3D graphene can be further engineered together with various functional components, especially the high loading (≈15 wt.%) and well-dispersed (an average diameter of less than 50nm) high-entropy alloy nanoparticles. Furthermore, combined with the 3D printing strategy, the rapid construction of graphene with complex and accurate 3D shapes is demonstrated via a selective in situ laser transforming (SLT) strategy. With the high structural integrity unachievable by traditional 3D printing methods, the obtained objects show an electrical conductivity of 4380 Sm-1 and a compressive modulus of 31.8MPa. The results reported in this work will open up a new way for the fabrication of functional carbon materials with customizable shapes and components.

Room-Temperature Pseudo-Solid-State Iron Fluoride Conversion Battery with High Ionic Conductivity.

Li-metal batteries (LMBs) employing conversion cathode materials (e.g., FeF3) are a promising way to prepare inexpensive, environmentally friendly batteries with high energy density. Pseudo-solid-state ionogel separators harness the energy density and safety advantages of solid-state LMBs, while alleviating key drawbacks (e.g., poor ionic conductivity and high interfacial resistance). In this work, a pseudo-solid-state conversion battery (Li-FeF3) is presented that achieves stable, high rate (1.0 mA cm-2) cycling at room temperature. The batteries described herein contain gel-infiltrated FeF3 cathodes prepared by exchanging the ionic liquid in a polymer ionogel with a localized high-concentration electrolyte (LHCE). The LHCE gel merges the benefits of a flexible separator (e.g., adaptation to conversion-related volume changes) with the excellent chemical stability and high ionic conductivity (∼2 mS cm-1 at 25 °C) of an LHCE. The latter property is in contrast to previous solid-state iron fluoride batteries, where poor ionic conductivities necessitated elevated temperatures to realize practical power levels. The stable, room-temperature Li-FeF3 cycling performance obtained with the LHCE gel at high current densities paves the way for exploring a range of architectures including flexible, three-dimensional, and custom shape batteries.

3D Printing in Regenerative Medicine: Technologies and Resources Utilized

Over the past ten years, the use of additive manufacturing techniques, also known as "3D printing", has steadily increased in a variety of scientific fields. There are a number of inherent advantages to these fabrication methods over conventional manufacturing due to the way that they work, which is based on the layer-by-layer material-deposition principle. These benefits include the accurate attribution of complex, pre-designed shapes, as well as the use of a variety of innovative raw materials. Its main advantage is the ability to fabricate custom shapes with an interior lattice network connecting them and a porous surface that traditional manufacturing techniques cannot adequately attribute. Such structures are being used for direct implantation into the human body in the biomedical field in areas such as bio-printing, where this potential is being heavily utilized. The fabricated items must be made of biomaterials with the proper mechanical properties, as well as biomaterials that exhibit characteristics such as biocompatibility, bioresorbability, and biodegradability, in order to meet the strict requirements that such procedures impose. The most significant biomaterials used in these techniques are listed in this work, but their advantages and disadvantages are also discussed in relation to the aforementioned properties that are crucial to their use.

3D Electrohydrodynamic Printing of Contact Lens‐Like Chloramphenicol‐Loaded Patches for Corneal Abrasions Treatment

Corneal abrasion is a common traumatic emergency, which can cause eyelid photophobia, tearing, and obvious foreign body sensation and pain. Herein, the 3D contact lens‐like chloramphenicol‐loaded patches composed of well‐organized micrometer fibers are prepared via electrohydrodynamic (EHD) printing to treat corneal abrasions. The main material of these patches is cellulose acetate (CA), and chloramphenicol (CAM) is loaded in the patches. EHD printing can realize micrometer fibers stacked layer by layer to form a customizable shape suitable for eye wear. Herein, the surface morphology, chemical as well as physical properties, transparency, drug release behaviors, and biocompatibility of the patches loading various concentrations of CAM are studied. It is found that the CAM‐loaded patches have 3D hemispherical shape similar to contact lens and smooth surface morphology. Moreover, patches loaded with different concentrations of CAM all maintain good water absorption, hydrophilicity, light transmittance, and biocompatibility. The drug release curves of CAM‐loaded patches show that the contact lens‐like patches have high loading efficiency and can achieve sustained release of CAM, indicating clinical potential in the treatment of corneal abrasions.

Design of Arbitrary Magnetic Patterns on Magnetic Polymer Composite Objects: A Finite Element Modelling Tool.

Magnetic sensor systems integrate a sensing element and magnetic field generators to determine their relative position or to measure movement. Typically, the magnetic fields are produced by permanent magnets, which have high intensity but are hard to machine into custom shapes. However, novel solutions using magnetic polymer composites (MPCs) have emerged as field generators due to their low cost, weight and patterning freedom. Here, we present a finite element model developed in COMSOL Multiphysics that allows the design of complex magnetization patterns on these polymer composites, taking into account the geometries of the parts and the magnetic properties of the materials employed. The model, together with the characterization protocol of the materials, has proved to be capable of predicting the magnetization of polymer composites at different temperatures. In addition, the model incorporates the properties of the magnets used during the magnetization process, such as the size, shape and magnetization, as well as the properties of the surrounding elements. This new model facilitates the design of new polymeric parts with complex shapes and magnetization patterns that can be employed as field generators in magnetic sensing systems.