Custom Jig Research Articles

A comparison between rib fracture patterns in peri- and post-mortem compressive injury in a piglet model

ObjectivesForensic biomechanics is increasingly being used to explain how observed injuries occur. We studied infant rib fractures from a biomechanical and morphological perspective using a porcine model. MethodsWe used 24, 6th ribs of one day old domestic pigs Sus scrofa, divided into three groups, desiccated (representing post-mortem trauma), fresh ribs with intact periosteum (representing peri-mortem trauma) and those stored at -20°C. Two experiments were designed to study their biomechanical behaviour fracture morphology: ribs were axially compressed and subjected to four-point bending in an Instron 3339 fitted with custom jigs. Morphoscopic analysis of resultant fractures consisted of standard optical methods, micro-CT (μCT) and Scanning Electron Microscopy (SEM). ResultsDuring axial compression fresh ribs did not fracture because of energy absorption capabilities of their soft and fluidic components. In flexure tests, dry ribs showed typical elastic–brittle behaviour with long linear load-extension curves, followed by short non-linear elastic (hyperelastic) behaviour and brittle fracture. Fresh ribs showed initial linear-elastic behaviour, followed by strain softening and visco-plastic responses. During the course of loading, dry bone showed minimal observable damage prior to the onset of unstable fracture. Frozen then thawed bone showed similar patterns to fresh bone. Morphologically, fresh ribs showed extensive periosteal damage to the tensile surface with areas of collagen fibre pull-out along the tensile surface. While all dry ribs fractured precipitously, with associated fibre pull-out, the latter feature was absent in thawed ribs. ConclusionsOur study highlights the fact that under controlled loading, fresh piglet ribs (representing perimortem trauma) did not fracture through bone, but was associated with periosteal tearing. These results suggest firstly, that complete lateral rib fracture in infants may in fact not result from pure compression as has been previously assumed; and secondly, that freezing of bone during storage may affect its fracture behaviour.

Plate fixation in the cervical spine: traditional paramedian screw configuration compared with unique unilateral configuration

This study compared the fixing strength and stability achieved by a unilateral plate and screw configuration against a standard cervical fixation plate using a single-level corpectomy and allograft strut graft model. Multidirectional in vitro flexibility tests were performed using a robotic spine testing system. Human cadaveric spines were assessed for spinal stability after vertebral corpectomy and anterior instrumentation. Specimens were mounted cranially and caudally on custom jigs that were then attached to load cells on the robotic system's end effector and base pedestal. C2-T1 spine specimens (n = 6) were tested intact; then after C-5 corpectomy (the vertebral body was excised), allograft placement and anterior plate fixation were performed. The surgeons performed a uniform corpectomy and reconstruction of each specimen in a protocol fashion. Two plates were compared: a unilateral 4-hole cervical plate designed to obtain rigid fixation using 4 convergent fixation screws all placed unilateral to the vertebral midline, and a standard cervical plate with bilateral plate screw configuration. The plate testing sequence was selected at random to limit bias. Fixation screws were matched for length and diameter. Pure moments were applied under load control (maximum 1.8 Nm) in flexion, extension, left/right lateral bending, and left/right axial rotation. Vertebral motion was measured using an optoelectronic system. The mean relative range of motion between C-4 and C-6 was compared among groups using repeated-measures ANOVA (significance level of 0.05). In comparing the intact construct and 2 different plates in all planes of motion, only motion in extension (intact vs. unilateral plate, p = 0.003; intact vs. standard plate, p = 0.001) and left axial rotation (intact vs unilateral plate, p = 0.019) were significantly affected. In terms of immediate cervical stability after 1-level corpectomy and placement of an allograft reconstruction, the unilateral plate showed comparable stiffness to the standard plate in all 3 motion planes (flexion [p = 0.993], extension [p = 0.732], left lateral bending [p = 0.683], right lateral bending [p = 0.546], left axial rotation [p = 0.082], and right axial rotation [p = 0.489]). The unilateral plate showed a trend toward improved stiffness in axial rotation. In no direction did the unilateral configuration prove significantly less stiff than the traditional configuration. The unilateral plate design proposed here requires minimal dissection and retraction beyond the midline of tissues susceptible to scar, postoperative pain, and swelling. The authors' study suggests that a unilateral plate can be configured to provide comparable fixation strength and torsional stiffness compared with traditional, widely accepted plate designs.

Radioscapholunate Arthrodesis With Excision of the Distal Scaphoid: Comparison of Contact Characteristics to the Intact Wrist

To evaluate the midcarpal contact characteristics at the lunocapitate (LC) and scaphotrapezio-trapezoidal (STT) joints in 3 wrist conditions: intact, after simulating a radioscapholunate (RSL) arthrodesis, and after an RSL arthrodesis with distal scaphoid excision (DSE). Eight fresh-frozen cadaveric specimens were tested using a custom jig with the wrist in neutral, 15° and 30° flexion and extension, 10° radial deviation, and 20° ulnar deviation. The RSL arthrodesis was performed using 2.4-mm distal radius plates with locking screws. Using a pressure sensor, contact force, average pressure, peak pressure, and contact area at the STT and LC joints were measured for 3 conditions: intact wrist, RSL arthrodesis, and RSL arthrodesis with DSE. Following RSL arthrodesis, average and peak pressure at the LC joint increased significantly compared to the intact wrist. In the STT joint, the average and peak contact pressure increased significantly compared to the intact wrist. Following DSE, average and peak pressure at the LC joint increased further compared to the RSL arthrodesis condition. Our findings showed increased contact pressures in the STT and LC joint following RSL arthrodesis, which may explain the clinical findings of midcarpal arthritis. Also, although DSE may improve short-term range of motion and clinical incidence of midcarpal arthritis, our findings showed that this comes at a cost, as the remaining portions of the midcarpal joint are subject to higher forces and pressures following DSE. Radioscapholunate arthrodesis results in increased midcarpal contact pressures that may explain the clinical incidence of midcarpal arthritis. Excision of the distal scaphoid further increases contact pressures in the remaining midcarpal joint and may further increase the incidence of midcarpal arthritis. These alterations in contact characteristics of the midcarpal joint should be considered when excising the distal scaphoid for improved range of motion.

Compressive rib fracture: Peri-mortem and post-mortem trauma patterns in a pig model

Despite numerous studies on high impact fractures of ribs, little is known about compressive rib injuries. We studied rib fractures from a biomechanical and morphological perspective using 15, 5th ribs of domestic pigs Sus scrofa, divided into two groups, desiccated (representing post-mortem trauma) and fresh ribs with intact periosteum (representing peri-mortem trauma). Ribs were axially compressed and subjected to four-point bending in an Instron 3339 fitted with custom jigs. Morphoscopic analysis of resultant fractures consisted of standard optical methods, micro-CT (μCT) and scanning electron microscopy (SEM). During axial compression, fresh ribs had slightly higher strength because of energy absorption capabilities of their soft and fluidic components. In flexure tests, dry ribs showed typical elastic-brittle behaviour with long linear load-extension curves, followed by relatively short non-linear elastic (hyperelastic) behaviour and brittle fracture. Fresh ribs showed initial linear-elastic behaviour, followed by strain softening, visco-plastic responses. During the course of loading, dry bone showed minimal observable damage prior to the onset of unstable fracture. In contrast, fresh bone showed buckling-like damage features on the compressive surface and cracking parallel to the axis of the bone. Morphologically, all dry ribs fractured precipitously, whereas all but one of the fresh ribs showed incomplete fracture. The mode of fracture, however, was remarkably similar for both groups, with butterfly fractures predominating (7/15, 46.6% dry and wet). Our study highlights the fact that under controlled loading, despite seemingly similar butterfly fracture morphology, fresh ribs (representing perimortem trauma) show a non-catastrophic response. While extensive strain softening observed for the fresh bone does show some additional micro-cracking damage, it appears that the periosteum may play a key role in imparting the observed pseudo-ductility to the ribs. The presence of fibrous pull-out and grooving of the outer tensile surface associated with periosteal stretching suggests that the periosteum under tension is able to sustain very high strain and bridge the mouth of the extending butterfly crack, thereby contributing to the observed strain-softening behaviour.

Surgical Technique: Computer-generated Custom Jigs Improve Accuracy of Wide Resection of Bone Tumors

Manual techniques of reproducing a preoperative plan for primary bone tumor resection using rudimentary devices and imprecise localization techniques can result in compromised margins or unnecessary removal of unaffected tissue. We examined whether a novel technique using computer-generated custom jigs more accurately reproduces a preoperative resection plan than a standard manual technique. Using CT images and advanced imaging, reverse engineering, and computer-assisted design software, custom jigs were designed to precisely conform to a specific location on the surface of partially skeletonized cadaveric femurs. The jigs were used to perform a hemimetaphyseal resection. We performed CT scans on six matched pairs of cadaveric femurs. Based on a primary bone sarcoma model, a joint-sparing, hemimetaphyseal wide resection was precisely outlined on each femur. For each pair, the resection was performed using the standard manual technique on one specimen and the custom jig-assisted technique on the other. Superimposition of preoperative and postresection images enabled quantitative analysis of resection accuracy. The mean maximum deviation from the preoperative plan was 9.0 mm for the manual group and 2.0 mm for the custom-jig group. The percentages of times the maximum deviation was greater than 3 mm and greater than 4 mm was 100% and 72% for the manual group and 5.6% and 0.0% for the custom-jig group, respectively. Our findings suggest that custom-jig technology substantially improves the accuracy of primary bone tumor resection, enabling a surgeon to reproduce a given preoperative plan reliably and consistently.

Biomechanical Evaluation of Suture-Augmented Locking Plate Fixation for Proximal Third Fractures of the Olecranon

To describe a method of suture augmentation of locking plate fixation (PF) of proximal olecranon fractures and to evaluate the biomechanical effectiveness of the suture augmentation using a human cadaveric model. Six matched pairs of cadaveric elbows were used. Proximal one-third fractures of the olecranon were simulated via a transverse osteotomy. Identical locking PF was performed on each elbow using olecranon locking plates. One elbow of each pair was assigned to suture augmentation of the construct. The choice of left/right specimen for augmentation was performed in an alternating fashion. Augmentation was performed using a no. 2 ultra-high-molecular weight polyethylene-braided suture attaching the triceps to the plate via a modified Krackow stitch. The elbows were mounted into a custom jig and linearly loaded to failure using a hydraulic testing machine. Load to and modes of failure were recorded for each sample. The data were analyzed using the Wilcoxon signed-rank test for nonparametric distributions. Suture augmentation improved the single load-to-failure strength in all pairs. One pair was excluded due to failure of the triceps attachment to the test machine. A median 398 N (P = 0.04 range, 197-633 N) or a median 48% (range, 30%-130%) improvement in strength was seen. The most common mode of failure was loss of fixation of the proximal olecranon fragment. Suture augmentation can significantly increase the single load-to-failure strength of locking PF for proximal olecranon fractures.

Use of a custom alignment guide to improve glenoid component position in total shoulder arthroplasty

Total and reverse total shoulder arthroplasty (TSA) are used to treat patients with glenohumeral joint osteoarthritis. The revision rate remains high compared with hip and knee arthroplasty. Glenoid component loosening is an important complication and may be caused by poor positioning of the component. We aimed to evaluate the safety and accuracy of a custom glenoid jig created using preoperative computed tomography (CT) imaging with 3D modelling for glenoid component implantation. Preoperative CT scans of each shoulder (N = 7) were obtained. Implants were virtually aligned and custom templates were created for intraoperative use. A two-part custom jig was manufactured for alignment of the central peg and the peripheral screws. Three-dimensional orientation of the component and screws was evaluated in postoperative CT scans. The difference between the preoperative plan and the result was then calculated. No technical difficulties or complications occurred. The mean absolute difference between the planned alignment and the postoperative placement of the glenoid component in the three-dimensional space was 3.4 mm (SD = 1 mm). The total average difference for all screws (N = 10) was 6.3° (SD = 3.2°). A CT-based custom glenoid component alignment can reliably guide the placement of the glenoid component during conventional and reverse TSA. This custom jig may be useful for optimizing glenoid component position in the setting of reverse and TSA.

A mechanical comparison of spinous process screwing and pedicle screwing in posterior internal fixation of C2

Objective To compare the pullout strength between spinous process screwing and pedicle screwing in posterior internal fixation of C2. Methods Eight fresh human cadaveric C2 were harvested.Spinous process screws were placed on one side of the C2 and pedicle screws were placed on the other side in a random manner.Cortical bone screws of 4.0 mm in diameter were used.The starting point for spinous process screw insertion was located at the junction of the lamina and the spinous process and the direction of the screw was about 0° caudally in the sagittal plane and about 0° medially in the axial plane.Pedicle screws were placed under direct visualization.After screw placement,each aet of vertebral bodies were mounted in a custom jig for axial pullout testing using a servo-hydraulic testing machine.The load-displacement curves were obtained for each screw pullout. Results The mean pullout strength for the spinous process screws was 387.56 ± 137.73 N,not significantly different from that for the pedicle screws (465.25 ± 214.32 N)( t =-0.862,P =0.403).The working length for the spinous process screws (21.42 ± 1.14 mm) was significanfly shorter than for the pedicle screws (23.16 ± 1.01 mm) ( t =4.368,P ＜0.001). Conclusion Since spinous process screws have similar pullout strength as compared with pedicle screws,they are biomechanically feasible in clinical application. Key words: Axis; Biomechanics; Internal fixators; Screws

The Effect of Dynamic Femoroacetabular Impingement on Pubic Symphysis Motion

Background: A link between femoroacetabular impingement and athletic pubalgia has been reported clinically. One proposed origin of athletic pubalgia is secondary to repetitive loading of the pubic symphysis, leading to instability and parasymphyseal tendon and ligament injury. Hypothesis/Purpose: The purpose of this study was to investigate the effect of simulated femoral-based femoroacetabular impingement on rotational motion at the pubic symphysis. The authors hypothesize that the presence of a cam lesion leads to increased relative symphyseal motion. Study Design: Controlled laboratory study. Methods: Twelve hips from 6 fresh-frozen human cadaveric pelvises were used to simulate cam-type femoroacetabular impingement. The hips were held in a custom jig and maximally internally rotated at 90° of flexion and neutral adduction. Three-dimensional motion of the pubic symphysis was measured by a motion-tracking system for 2 states: native and simulated cam. Load-displacement plots were generated between the internal rotational torque applied to the hip and the responding motion in 3 anatomic planes of the pubic symphysis. Results: As the hip was internally rotated, the motion at the pubic symphysis increased proportionally with the degrees of the rotation as well as the applied torque measured at the distal femur for both states. The primary rotation of the symphysis was in the transverse plane and on average accounted for more than 60% of the total rotation. This primary motion caused the anterior aspect of the symphyseal joint to open or widen, whereas the posterior aspect narrowed. At the torque level of 18.0 N·m, the mean transverse rotation in degrees was 0.89° ± 0.35° for the native state and 1.20° ± 0.41° for cam state. The difference between cam and the native groups was statistically significant (P < .03). Conclusion: Dynamic femoroacetabular impingement as caused by the presence of a cam lesion causes increased rotational motion at the pubic symphysis. Clinical Relevance: Repetitive loading of the symphysis by cam impingement is thought to lead to increased symphyseal motion, which is one possible precursor to athletic pubalgia.

An Anatomic and Biomechanical Study of the Oblique Retinacular Ligament and Its Role in Finger Extension

To analyze the anatomy and contribution of the oblique retinacular ligament (ORL) to distal interphalangeal (DIP) joint extension force with varying angles of proximal interphalangeal (PIP) and metacarpophalangeal (MCP) joint flexion. Forty fresh-frozen fingers were dissected. The fingers were mounted in a custom jig, and the force required to flex the DIP joint was assessed with the PIP joint flexed 0°, 30°, 60°, and 90° and with the MCP joint flexed 0°, 45°, and 90°. The force was measured in the intact specimen, and then all measurements were repeated following sectioning of the ORL and then the central slip. The ORL was present on the radial and ulnar aspects of all but 2 fingers. The ORL tended to be the most robust in the ring finger. In the intact specimen, DIP flexion resistance force was maximum at 30° of PIP joint flexion and minimum at 90° of PIP joint flexion. There was a significant difference between the 90° position and all other positions of the PIP joint with respect to flexion force in the intact specimen. This meant that less force was required to flex the DIP joint at 90° of PIP joint flexion. Sectioning of the ORL revealed that it contributed 25% to the total force required to flex the DIP joint with the PIP joint at 0°, 31% at 30°, 18% at 60°, and 3% at 90° of flexion. The MCP joint position had no effect. Sectioning the central slip produced a significant increase in force required to flex the DIP joint at 90° of PIP joint flexion. In this study, the ORL was usually present, and it contributed up to 30% of the passive resistance to DIP joint flexion. The intact central slip accounted for the decrease in DIP joint extensor tone at 90° of PIP joint flexion. The ORL plays a small role in passively resisting DIP flexion.

Electromechanical reshaping of costal cartilage grafts: A new surgical treatment modality

Needle electrode-based electromechanical reshaping (EMR) is a novel, ultra-low-cost nascent surgical technology to reshape cartilage with low morbidity. EMR uses direct current to induce mechanical relaxation in cartilage that is first deformed into a required geometry, which in turn leads to permanent shape change. The objective of this study was to determine the effect of EMR voltage and time on the shape change of costal cartilage grafts. EMR of ex vivo porcine costal cartilage. Graft specimens obtained from the central core of porcine costal cartilage were bent at a 90-degree angle with a custom jig and then reshaped via EMR. The effects of voltage (3-7 V) and application time (1-5 minutes) on the amount of shape change were systematically examined. Bend angles were analyzed using analysis of variance and paired t tests to determine significant reshaping times at each voltage setting. There is a threshold for voltage and time above which the retention of bend angle is statistically significant in treated specimens compared to the control (P < .05). Above the threshold of 3 V, shape retention initially increased with application time for all voltages tested and was then observed to reach a plateau. Shape retention was noted to be greatest at 6 V without a rise in temperature. EMR provides a novel method to bend and shape costal cartilage grafts for use in facial plastic surgery. A low voltage can reshape cartilage grafts within several minutes and without the heat generation. This study demonstrates the feasibility of EMR and brings this minimally invasive procedure closer to clinical implementation.

Archwire depth is a significant parameter in the frictional resistance of active and interactive, but not passive, self-ligating brackets

To elucidate some of the parameters determining the frictional behavior of passive, active, and interactive self-ligating brackets during sliding mechanics. A custom jig mimicking the three-dimensional tooth movements that occur during sliding mechanics and an Instron testing machine were used to determine the resistance to sliding of six different self-ligating brackets (SPEED, In-Ovation C, CarrièreSLB, ClaritySL, SmartClip, VisionLP). Each bracket was tested on three rectangular stainless steel wires: 0.017 × 0.022 inch, 0.017 × 0.025 inch, and 0.019 × 0.025 inch. A two-way balanced analysis of variance was used for statistical analysis. The four passive self-ligating brackets (CarrièreSLB, ClaritySL, SmartClip, VisionLP) displayed significantly lower frictional resistance (P < .001) than the remaining brackets, which featured an active (SPEED) or interactive (In-Ovation C) clip. The SPEED bracket consistently demonstrated the highest resistance to sliding. The mode of self-ligation appears to be the primary variable in determining the frictional behavior of orthodontic brackets undergoing sliding mechanics. Passive self-ligating brackets demonstrated significantly lower frictional resistance to sliding. With regard to the resistance of active self-ligating brackets, the depth (buccolingual thickness) of the wire had a more significant influence than its height.

The impact of capitellar arthroplasty on elbow contact mechanics: Implications for implant design

BackgroundRadiocapitellar arthroplasty is indicated for capitellar deficiency. Although current implants employ a spherical capitellar surface, the capitellum is elliptical. This has implications for congruency and wear in capitellar arthroplasty. Our objective was to evaluate the contact mechanics of radiocapitellar arthroplasty. We hypothesized that capitellar replacement would decrease joint contact area relative to the native articulation; and an anatomical implant design would replicate more normal contact morphology than a spherical implant. MethodsEight paired humeri and radii were potted in a custom jig. A compressive load of 85N was applied with the articulation flexed at 45° in neutral forearm rotation. Joint casts were made and the articular contact area and shape were quantified. Anatomical and spherical capitellar implants were tested against the native radial head (hemiarthroplasty). FindingsThe contact areas for the anatomical and spherical hemiarthroplasties were 59 and 51% of the native articulation (P<0.005), while the unicompartmental arthroplasties' contact areas were 84 and 89% (anatomical, spherical) of the native articulation (P<0.01). No implant was superior in recreating the native contact shape. InterpretationPlacement of any capitellar implant resulted in a large decrease in contact area when articulating with a native radial head. This suggests that the radial head cartilage would see a marked increase in contact pressure relative to the native articulation. The unicompartmental arthroplasties demonstrated an even larger reduction in contact area, raising concern about accelerated surface wear. Further investigation needs to correlate these contact mechanics to cartilage wear and implant longevity.

Knotless Rotator Cuff Repair in an External Rotation Model: The Importance of Medial-Row Horizontal Mattress Sutures

To evaluate the effect of the addition of 2 horizontal mattress knots to the medial row of a knotless rotator cuff construct on the biomechanical properties in terms of both cyclic and failure testing parameters in an external rotation model. In 8 fresh-frozen human cadaveric shoulders, a knotless transosseous repair was performed, whereas in 8 contralateral matched-pair specimens, 2 horizontal mattress knots were added to the medial-row fixation. A custom jig was used that allowed external rotation (0° to 30°) with loading. A materials testing machine was used to cyclically load repairs from 0 to 180 N for 30 cycles and then to failure. Video digitizing software was used for analysis. Data from paired specimens were compared by use of paired Student t tests. Ultimate load to failure was significantly higher in the modified construct (549 N v 311 N, P = .01). Linear stiffness in the first cycle, at the 30th cycle, and at failure was significantly higher (P = .02, P = .02, and P = .04, respectively) in the modified construct as well. Energy absorbed by the repaired tissue was significantly less in the modified construct at the first cycle, at the 30th cycle, and at ultimate load to failure (P = .03, P = .02, and P = .04, respectively). Significantly greater anterior gap formation occurred with the knotless technique at the first cycle (4.55 v 1.35) and 30th cycle (7.67 mm v 1.77 mm) (P = .02). The modified construct shows improved biomechanical properties when allowing for external rotation during high-load testing. Using an additional horizontal mattress from separate sutures in the medial-row anchors helps to neutralize forces experienced by the repair. The addition of medial-row fixation to a knotless construct will enhance the stability of rotator cuff repairs with the goal of improved patient outcomes.

Acetabular Ventroversion with Double Pelvic Osteotomy Versus Triple Pelvic Osteotomy: A Cadaveric Study in Dogs

To determine which of 3 different plate angles (20°, 25°, 30°) used in double pelvic osteotomy (DPO) would result in the most similar acetabular angle (AA) achieved with a 20° triple pelvic osteotomy (TPO) technique in dogs. Experimental anatomic study. Cadaveric canine pelves (n = 8). Transverse plane computed tomographic images of cadaveric pelves with intact sacroiliac joints, mounted in a custom jig, were made (baseline) and again after DPO (20°, 25°, 30°) and TPO (20°) and pelvic angles measured in 6 transverse planes. Pelvic angles of the 3 DPO techniques were compared with TPO using concordance correlation to determine which DPO angle resulted in an acetabular ventroversion angle closest to TPO. Mean ± SD AAs were 32.89 ± 2.23 (baseline), 47.39 ± 4.39 (20° DPO), 51.43 ± 5.06 (25° DPO), 54.75 ± 4.38 (30° DPO), and 50.20 ± 5.76 (20° TPO). Concordance correlations for the AA compared with 20° TPO were 0.027 (baseline), 0.721 (20° DPO), 0.902 (25° DPO), and 0.593 (30° DPO). A concordance correlation of ≥ 0.8 indicates good correlation. A 25° DPO is most similar in acetabular ventroversion to 20° TPO (concordance correlation, 0.902).

The impact of ulnar collateral ligament tear and reconstruction on contact pressures in the lateral compartment of the elbow

Complete ulnar collateral ligament (UCL) injury increases articular pressure and reduces contact area compared with the normal intact UCL. UCL reconstruction restores the contact area and contact pressure observed in the native joint. Six male cadaveric elbows were mounted on a custom jig capable of simulating the 2 critical phases of the throwing motion during pitching. A contact sensor was placed through an anterior arthrotomy into the radiocapitellar joint. Each specimen then underwent valgus loading at 1.75 and 5.25 Nm of torque with the biceps, brachialis, and triceps under axial load in each testing condition. The average valgus laxity in the intact elbow at 90° was 3.7° ± 0.6° at the 5.25 Nm level of torque, which doubled after transection. The reconstruction group demonstrated less laxity (2.4° ± 0.4°) and reduced valgus angulation of the ulna at 5.25 Nm of torque. The transected UCL condition showed peak contact pressure 67% higher compared with the native ligament group at 5.25 Nm of torque. The reconstructed group increased peak articular cartilage pressures by 33% from the native ligament. At 5.25 Nm of torque for the 90° flexion phase, the transected UCL condition showed an average contact pressure of 84% greater than that of the native ligament group. Reconstruction of the UCL restored average articular pressures to within 20% of intact values at 90°. UCL injury increases radiocapitellar contact pressures and reduces resistance of the elbow to valgus loading. Contact pressures and valgus laxity can be improved with UCL reconstruction. Taken as a whole, the peak pressure data indicate that the reconstruction restores valgus stability and lateral contact pressures to nearly normal levels under the conditions tested. Because the 90 position is the clinically significant position, these laboratory data support the clinical success of the docking procedure.

A cadaver model evaluating femoral intramedullary reaming: a comparison between new reamer design (Pressure Sentinel) and a novel suction/irrigation reamer (RIA)

Objective To compare the intramedullary pressures developed during reaming of cadaveric femurs with the Synthes Reamer/Irrigator/Aspirator (RIA) reamer and the Zimmer Pressure Sentinel (PS) reamer, controlling for the force and speed of reaming. Method Fifteen matched pairs of frozen unpreserved femurs were used in the study. Two pressure transducers and two thermocouples were screwed into holes drilled into the femoral shaft. The femurs were stabilized in the vertical position by mechanically attaching them to a custom jig equipped with a load cell to detect the vertical component of force applied to the reamer. Proximally a linear voltage displacement transducer (LVDT) was attached to the reamer to record the continuous position of the reamer. All femurs were reamed to a diameter 2 mm larger than the narrowest point of the canal. Proximal and distal pressures, proximal and distal temperatures, applied vertical force and displacement were measured continuously throughout the reaming process. Maximum and minimum, and average proximal and distal pressures for each reamer were obtained and compared using paired t-tests. Averages were also calculated and compared in the same manner. A p-value of <0.05 was considered statistically significant. Results The maximum, minimum and average intramedullary pressures during reaming were significantly lower with the RIA system than the PS reamer. In general, the pressures produced by the RIA system were consistently below atmospheric pressure for the majority of the reaming time. This was not true for the PS system. No appreciable temperature changes were observed during any of the trials. Conclusion The RIA reaming system significantly reduces the intramedullary pressures produced during the reaming process compared to the PS reaming system.

Moments generated by simple V-bends in nickel titanium wires

This study compared the moments produced by V-bends placed in rectangular nickel titanium (NiTi) orthodontic wire to those produced in titanium-molybdenum alloy (TMA). V-bends that included angles of 135, 150, and 165 degrees were heat set into 0.017×0.025 and 0.016×0.025 inch NiTi alloy wires and identical bends bent into TMA wires with a dimension of 0.018×0.025 and 0.016×0.022 inch. There were five specimens per group (N=60). The moments produced by each specimen were tested on a custom jig that aligned two lower incisor brackets with zero tip or torque at an interbracket distance of 15 mm. The upper bracket was connected to a moment transducer. The V-bend position for each specimen was varied in 1 mm increments towards the moment transducer. The moments produced by TMA wires were linear, which increased as the V-bend approached the transducer, while NiTi exhibited a non-linear curve characterized by a flattening of the moment value. The point of dissociation (where the moment experienced by the bracket became zero) was estimated for both wire types using linear mixed model analysis. For TMA wires, this point was similar to that reported in the literature but was significantly less for NiTi wire when compared with TMA. The moments produced by TMA generally increased with the magnitude of the V-bend, whereas this was not the case for NiTi.

An Interlocking Ligamentous Spinal Disk Arthroplasty with Neural Network Infrastructure

An elastomeric spinal disk prosthesis design (BioFI™) with vertebral interlocking anchors has been modified using an embedded TiNi wire array. Bioinert styrenic block copolymer (Kraton®) and polycarbonate urethane (Bionate®) thermoplastic elastomer (TPE) matrices were utilized. Fatigue resistant NiTi wire was pretreated to induce superelastic martensitic microstructure. Stent-like helical structures were produced for incorporation within homogenous TPE matrix. Composite prototypes were fabricated in a vacuum hot press using transfer moulding techniques. Implant prototypes were subject to axial compression using a BOSE ® ELF3400. The NiTi reinforced implants exhibited reduction in axial strain, compliance, and creep compared to TPE controls. The axial properties of the NiTi reinforced Bionate® BioFI™ implant best approximated those of a spinal disk followed by Kraton®-NiTi, Bionate® and Kraton® prototypes. An ovine lumbar segment biomechanical model was used to characterize the disk prosthesis prototypes. Specimens were subject to 7.5Nm pure moments in axial rotation, flexion-extension and lateral bending with a custom jig mounted on an Instron® 8874. The motion preserving ligamentous nature of this arthroplasty prototype was not inhibited by NiTi reinforcement. Joint stiffness for all prototypes was significantly less than the intact and discectomy controls. This was due to lack of vertebral anchor rigidity rather than BioFI™ motion segment matrix type or reinforcement. Implant stress profiles for axial compression and axial torsion conditions were obtained using finite element methods. The biomechanical testing and finite element modelling both support existing BioFI™ design specifications for higher modulus vertebral anchors, endplates and motion segment periphery with gradation to a low modulus core within the motion segment. This closer approximation of the native spinal disk form translates to improvements in prosthesis biomechanical fidelity and longevity. Axial compressive strain induced within a TiNi reinforced Kraton® BioFI™ was found to be linearly proportional to the NiTi helical coil electrical resistance. This neural network capability delivers opportunities to monitor and telemeterize in situ multiaxis joint structural performance and in vivo spine biomechanics.

Additive manufacturing for in situ repair of osteochondral defects

Tissue engineering holds great promise for injury repair and replacement of defective body parts. While a number of techniques exist for creating living biological constructs in vitro, none have been demonstrated for in situ repair. Using novel geometric feedback-based approaches and through development of appropriate printing-material combinations, we demonstrate the in situ repair of both chondral and osteochondral defects that mimic naturally occurring pathologies. A calf femur was mounted in a custom jig and held within a robocasting-based additive manufacturing (AM) system. Two defects were induced: one a cartilage-only representation of a grade IV chondral lesion and the other a two-material bone and cartilage fracture of the femoral condyle. Alginate hydrogel was used for the repair of cartilage; a novel formulation of demineralized bone matrix was used for bone repair. Repair prints for both defects had mean surface errors less than 0.1 mm. For the chondral defect, 42.8 ± 2.6% of the surface points had errors that were within a clinically acceptable error range; however, with 1 mm path planning shift, an estimated ∼75% of surface points could likely fall within the benchmark envelope. For the osteochondral defect, 83.6 ± 2.7% of surface points had errors that were within clinically acceptable limits. In addition to implications for minimally invasive AM-based clinical treatments, these proof-of-concept prints are some of the only in situ demonstrations to-date, wherein the substrate geometry was unknown a priori. The work presented herein demonstrates in situ AM, suggests potential biomedical applications and also explores in situ-specific issues, including geometric feedback, material selection and novel path planning techniques.