Rate Curves Research Articles

Simultaneous bilateral open wedge high tibial osteotomy versus simultaneous bilateral unicompartmental knee arthroplasty in the treatment of bilateral medial knee osteoarthritis: a retrospective study of an average three-year follow-up

ObjectiveThere is growing evidence that simultaneous bilateral open wedge high tibial osteotomy(SBOWHTO) and simultaneous bilateral unicompartmental knee arthroplasty(SBUKA) is an effective surgical treatment for bilateral medial knee osteoarthritis (MKOA). However, which intervention is more beneficial for bilateral MKOA patients remains unknown. Therefore, the aim of this study was to compare the effectiveness of these two strategies through early clinical outcomes, complication rates, and prosthetic survival.MethodsThe clinical data of 60 patients with bilateral MKOA admitted to the Affiliated Hospital of Qingdao University from January 2018 to December 2022 were retrospectively analyzed, and they were divided into SBOWHTO group (n = 28) and SBUKA group (n = 32) according to different treatment methods. Clinical relevant indexes, Hospital for Special Surgery (HSS) score, Knee Society Knee (KSS) score, range of motion(ROM), postoperative complications and prosthetic survival rate were compared between the two groups.ResultsPatients in the SBOWHTO group were followed up for 27 to 50 months, with an average of (37.18 ± 6.84) months. Patients in the SBUKA group were followed up for 24 to 59 months, with an average of (39.38 ± 9.74) months. There were no significant differences in postoperative KSS, HSS and ROM between SBOWHTO group and SBUKA group (p > 0.05). There was no significant difference in complication rate between the two groups (p = 0.721). There was no significant difference in prosthetic survival rate (p = 0.622) and prosthetic survival curve (χ2 = 0.546, p = 0.46) between the two groups.ConclusionsThis study compared early clinical outcomes, complication rates, and prosthesis retention rates after SBOWHTO and SBUKA, and found that the early clinical benefits of SBOWHTO and SBUKA were comparable in patients with bilateral MKOA.

Photoprotective mechanisms activated in Antarctic moss <i>Chorisodontium aciphyllum</i> during desiccation

We investigated the relationship between relative water content (RWC) of Antarctic moss Chorisodontium aciphyllum and several chlorophyll fluorescence parameters evaluating primary photochemical processes of photosynthesis. During the gradual dehydration of Ch. aciphyllum from fully wet (RWC=100%) to dry (RWC=0%) state, progression of NPQ (non-photochemical quenching) induction curves were recorded; the maximum NPQ (NPQmax) attained at the end of illumination period (10 min.), and NPQ relaxation in dark were all analysed. Induction curves of photosynthetic electron transport rate (ETR) were also evaluated, as well as two parameters, ETRmax and initial slop, were derived from the curve: (1) ETRmax; (2) initial slope (a parameter). The two parameters were related to the degree of desiccation (RWC decdlining from 100 to 0%). It was found that NPQ induction curves and the parameters derived from them were sensitive to dehydration and may be used as markers for dehydration-induced changes in photosystem II functioning of desiccating Ch. aciphyllum. The activation of non-photochemical quenching during desiccatin and the underlying mechanisms are discussed.

Computational influences of convection micropolar fluid influx and permeability on characteristics of heating rate and skin friction over vertical plate

This manuscript merits at examining of an embedded orthogonal plate inside porous domain exposed to uniform heat influx to elaborate on how micro polar fluid factors and permeability characteristic affect the local skin friction, heating rate, and angular velocity inside boundary layer. The plate is subjected to forced convective micro polar fluid influx under steady, incompressible, and viscous circumstances. To facilitate dependable numerical solution, similarity approach is implemented to mutate set of coupled governing equations relevant to the adopted study into a constrained dimensionless differential equations. Computational analysis has been executed hiring Runge-Kutta scheme by Matlab function bvp4c to settle the governing equations. Study's results are highlighted graphically the impact of micro polar fluid factors on the local skin friction, heating rate, and angular velocity curves. High degree of acceptability of present findings compare with prior research results. It is found that the rising of Darcy parameter drives to decrease linearly both heating rate and local skin friction. Among the examined factors, the benchmark parameter of decreasing skin friction is the porosity. Additionally, it is found that an increasing of Prandtl number and micro rotation element lead to enhance Nusselt number. Once curves of micro rotation are interfered at certain distance from the plate due to increase in porosity, Darcy, Forchheimer's, and microelement rotation, the micro rotation curves are inverted.

Revisiting elastic string models of forward interest rates

Twenty five years ago, several authors proposed to describe the forward interest rate curve (FRC) as an elastic string along which idiosyncratic shocks propagate, accounting for the peculiar structure of the return correlation across different maturities. In this paper, we revisit the specific ‘stiff’ elastic string field theory of Baaquie and Bouchaud [Stiff field theory of interest rates and psychological future time. Wilmott Mag., 2004, 2–6] in a way that makes its micro-foundation more transparent. Our model can be interpreted as capturing the effect of market forces that set the rates of nearby tenors in a self-referential fashion. The model is parsimonious and accurately reproduces the whole correlation structure of the FRC over the time period 1994–2023, with an error around 1% and with only one adjustable parameter, the value of which being very stable across the last three decades. The dependence of correlation on time resolution (also called the Epps effect) is also faithfully reproduced within the model and leads to a cross-tenor information propagation time on the order of 30 minutes. Finally, we confirm that the perceived time in interest rate markets is a strongly sub-linear function of real time, as surmised by Baaquie and Bouchaud [Stiff field theory of interest rates and psychological future time. Wilmott Mag., 2004, 2–6]. In fact, our results are fully compatible with hyperbolic discounting, in line with the recent behavioral Finance literature Farmer and Geanakoplos [Hyperbolic Discounting is Rational: Valuing the Far Future with Uncertain Discount Rates, Cowles Foundation Discussion Papers, 2009 (Cowles Foundation for Research in Economics, Yale University)].

Experimental and crystal plasticity study on hydrogen-assisted fatigue crack growth behavior of IN625 superalloy

The fatigue crack growth (FCG) behavior of IN625 alloy was studied by experimental methods and crystal plasticity simulations. Based on the experimental FCG rate curves, it is evident that hydrogen significantly accelerates FCG, and calculations show that this acceleration factor reaches a maximum of 2.41 times at 1 Hz. Hydrogen results in smaller plastic deformation zones compared to hydrogen-free samples. The interaction between hydrogen and dislocations leads to the nucleation of micro-voids along the slip planes, promoting the hydrogen-assisted cracking process. Lower loading frequencies results in finer fatigue striations and more pronounced hydrogen embrittlement features on the fracture surface.

Electrochemical sensing of vitamin B6 (pyridoxine) by adapted carbon paste electrode

The recent investigation targets to use adapted carbon paste (CP) with copper nanoparticles (CuNs) operating in a phosphate buffer (PBS) medium with a pH range of 5.0–8.0, to synthesize a novel, susceptible, and simple electrochemical sensor for the detection of one of the most important drugs, vitamin B6. Copper (Cu) is one of the most three common essential trace elements found in the bodies of both humans and animals, along with iron and zinc for all crucial physiological and biochemical functions. Its properties, which are assessed using a variety of methods including scanning electron microscopy (SEM), cyclic voltammetry (CV), differential pulse voltammetry (DPV), and electrochemical impedance spectroscopy (EIS), have also drawn a lot of attention recently. We considered the effects of pH, buffer, scan rate, interference, and calibration curve. The susceptible electrode's linear calibration curve encompassed concentration values between 8.88 and 1000.0 µM. The calculated limits of detection and quantification were 32.12 and 107.0 µM, respectively. Furthermore, this method was established in real human urine samples and drug validation which have been shown satisfactory results for vitamin B6 detection.

The Influence of FA Content on the Mechanical and Hydration Properties of Alkali-Activated Ground Granulated Blast Furnace Slag Cement

This study primarily investigates the effect of fly ash (FA) content on the mechanical properties and hydration performance of alkali-activated ground granulated blast furnace slag cement (AAGC) and compares the related properties with ordinary Portland cement (OPC). Additionally, we examined the hydration products; performed thermal analysis, MIP, and SEM; and determined chemically bound water and pH values of AAGC. The compressive strength of AAGC showed a retrogression phenomenon from 3 to 28 days, with the 14-day and 28-day compressive strengths of AAGC being higher than those of OPC. The AAGC with 20% FA content exhibited the highest 28-day compressive strength (75 MPa). The hydration heat release rate curve of OPC and AAGC was divided into the initial induction period, induction period, acceleration period, deceleration period, and steady period. As FA content increased, the 28-day pore volume of AAGC increased, while pH values and chemically bound water decreased. SEM images of AAGC with low FA content showed more microcracks.

Plasma Endocannabinoids Are Independently Associated With the Metabolic Function of White Adipose Tissue

Abstract Context Little is known about the link between the endocannabinoid (EC) system and the in vivo metabolic function of white adipose tissue (WAT). Objective We aimed to evaluate whether ECs are linked to postprandial fatty acid metabolism and WAT metabolic function. Methods Men and women, with (IGT, n = 20) or without impaired glucose tolerance (NGT, n = 20) underwent meal testing with oral and intravenous stable isotope palmitate tracers and positron emission tomography with intravenous [11C]-palmitate and oral [18F]-fluoro-thia-heptadecanoic acid to determine systemic and organ-specific dietary fatty acid (DFA) and nonesterified fatty acid (NEFA) metabolism and partitioning. We determined fasting and postprandial plasma levels of EC by ultra-high performance liquid chromatography–tandem mass spectrometry. Results All ECs of the 2-monoacylglycerol (2-MAG) family displayed a progressive postprandial increase up to 360 minutes after meal intake that was more pronounced in women with IGT. N-acylethanolamine (NAE) levels decreased between fasting and 180 minutes, followed by a return to preprandial values at 360 minutes and were also increased in women with IGT. Postprandial area under the curve (AUC) of palmitate appearance rate was significantly and independently associated with postprandial AUC of anandamide (AEA; P = .0003) and total energy expenditure (P = .0009). DFA storage in abdominal subcutaneous adipose tissue was positively predicted by fasting 2-arachidonoylglycerol (2-AG; P < .04). Conclusion EC levels of the NAE family independently follow plasma NEFA metabolism, whereas 2-MAG closely follow the spillover of triglyceride-rich lipoprotein intravascular lipolytic products. Whether these associations are causal requires further investigation.

Suspended Load Estimation in Data Scarce Rivers

AbstractSediment rating curves (SRCs) are tools of satisfactory reliability in the attempt to describe the sediment regime in catchments with limited or poor-quality records. The study valorised the most suitable SRC development method for the estimation of the coarse suspended sediment load at the outlet of nine Mediterranean sub-watersheds. Four established grouping techniques were assessed, to minimize the uncertainty of the results, namely simple rating curve, different ratings for the dry and wet season of the year, hydrographic classification, and broken line interpolation, at three major Greek rivers (Aliakmon, Acheloos – upper route, Arachthos). The methods’ performance was benchmarked against sediment discharge field records, utilizing statistical measures and graphical analyses. The necessary observations were conducted by the Greek Public Power Corporation. The results were site/station dependent, and no methodology emerged as universally accepted. The analysis designated that the simple rating curve performs best at the cross-sections Moni Ilarion, Moni Prodromou, and Arta bridge, the different ratings for the dry and wet season of the year at Grevena bridge and Gogo bridge, the hydrographic classification at Velventos and Plaka bridge, and the broken line interpolation at Avlaki dam and Tsimovo bridge. In this regard, the study advocates the use of multiple SRC methods. Despite its limitations, the method merits a rather simple and cost-effective generation of a (continuous, detailed, sufficiently accurate) synthetic suspended sediment discharge timeseries, with high interpolating, extrapolating and reproducibility potential. The success of the application could benefit, among others, water quality restoration and dam management operations.

High sensitivity potentiometric hydrogen sensor based on ZnFe2O4 electrode

Hydrogen is currently considered to be the best clean energy to replace fossil fuels, so hydrogen leak detection is crucial. The current research field of hydrogen sensors focuses on the discovery and optimization of sensitive materials. ZnFe2O4 powder is prepared by the sol-gel method and sintered at different temperatures. The effects of sintering temperature on electrode morphology and hydrogen sensing performance are investigated. The sensitivity reaches a maximum value of −101.32 mV/decade at the sintering temperature of 1100 °C. The sensor has different sensing performance at different operating temperatures. It has the best response value and sensitivity at 450 °C, and the best response/recovery rate and response curve stability at 550 °C. The sensor responds and recovers in seconds. The material has good H2 selectivity and is suitable for potentiometric hydrogen sensors. CO, NH3, and CH4 have less effect on the response signal and exhibit good long-term stability.

Maximum temperature of steel bridges due to multiple under-bridge fire sources

In this study, an analytical model was developed and predictive equations were proposed to estimate the maximum temperature of steel bridges in the event of a fire originating from complex facilities beneath the bridge. Based on statistical data, a representative shape of steel bridges in South Korea was selected. A representative Heat Release Rate (HRR) curve for the complex facility was selected, and a parametric study was conducted, including variables such as Heat Release Rate Per Unit Area (HRRPUA), fully developed time, vertical clearance, and the area of the complex facility. Through correlation analysis, key parameters influencing the maximum temperature in steel bridges were examined. Based on the results, both linear and non-linear temperature prediction equations were suggested. The non-linear equation demonstrated higher predictive performance than the linear equation. This study provides foundational data for enhancing the accuracy of fire analysis methods and temperature prediction models for steel bridges.

A highly sensitive, accurate, and stable method for measuring pectin depolymerase activity

Pectin depolymerase is widely utilized in various industrial sectors. However, the traditional methods for determining its enzymatic activity have limitations, such as cumbersome operations and a significant impact of enzyme solution dilution ratios on activity. The 3-methyl-2-benzothiazolinone hydrazone (MBTH) method can be employed to address these issues, but pectin precipitation and strong background commonly arise in this method. We have successfully overcome these challenges by employing a low-temperature and high-alkaline environment, and further optimized the reagent compositions and detection wavelength to improve the method. Consequently, enzyme hydrolysis follows a zero-order reaction within 60 min, which is helpful for the endpoint measurement of pectinase activity. The developed calibration curve for pectinase concentration and hydrolysis rate demonstrates linearity (R2 = 0.9945) within the range of 2.5–15.8 mU/mL of pectinase. This method exhibits high sensitivity, accuracy, and stability, making it suitable for routine determination of pectin depolymerase activity in research and applications.

Advancing regional flood mapping in a changing climate: A HAND‐based approach for New Jersey with innovations in catchment analysis

AbstractRegional flood mapping poses computational and spatial heterogeneity challenges, exacerbated by climate change‐induced uncertainties. This study focuses on creating a state‐wide flood mapping solution with enhanced accuracy and computational speed to support regional flooding hazard analysis and the assessment of climate change, using New Jersey as a case study. The Height Above Nearest Drainage (HAND) framework was employed for large‐scale flood mapping. The model was validated against high water marks (HWMs) collected after Hurricane Irene. Based on the National Water Model (NWM), synthetic rating curves in HAND were calibrated by tuning Manning's roughness, aligning the predicted and observed flood depths. The roughness values were generalized across the state from the validated water basins to the ungauged ones, using a multivariate regression with the hydrologic and geographic information. To map the future climate‐change‐induced flooding, a correlation between NOAA historical precipitation totals and NWM flow data from 2010 to 2020 was established to link precipitation and runoff. This study also invented a novel method for correcting catchment discontinuities, inherent in the HAND model, based on a computer vision scheme, the Sobel filter. The modeling results show that average and worst‐case storm events have the potential to increase 10%–50% in the state, where mountain areas and major river banks would be exposed to this impact more significantly.

Space radiation measured during first-ever commercial suborbital mission on Virgin Galactic SpaceShipTwo Unity on 29 June 2023

The paper presents the variations of space radiation (primary and secondary galactic cosmic rays (GCR) absorbed dose rate in silicon and flux) measured during the first-ever commercial suborbital flight of the Virgin Galactic (VG) SpaceShipTwo Unity on 29 June 2023. A Portable Dosimeter-Spectrometer Liulin-CNR-VG is used. It is developed in the Space Research and Technology Institute, Bulgarian Academy of Sciences (SRTI-BAS) under a scientific contract with National Research Council of Italy (CNR), Italy. Liulin-CNR-VG size is 63х54 × 23 mm. Its weight is 0.092 kg. During the first part of the SpaceShipTwo flight, up to 14.4 km, the dose rate rises from 0.058 μGy h-1 up to 2.5 μGy h-1. Above the altitude of 30 km, the dose rate falls to 2.2 μGy h-1, while the dose to flux ratio increases to values about 1.0 nGy cm2 particle-1. The latter confirms the outcomes of previous balloon experiments, i.e. the change of the composition of the radiation field of the GCR and secondary radiation source from predominantly light particles as electrons, pions and muons towards heavier particles as protons and neutrons. On the descending part of the flight, one maximum in the flux and dose rate curves is obtained as Regener-Pfotzer maximum (R-PM). The flux calculated by the moving avervage is equal to 1.2 cm-2 s-1 and the dose rate is equal to 2.9 μGy h-1 at an altitude of 13 km. These values are well in line with those expected in conditions of relatively high solar activity, such as during the flight. The dose rates measured by Liulin-CNR-VG are in good agreement with other Liulin data, such as those recorded during balloon flights in 2005 and 2015 and civil aviation flights. The calculated total equivalent dose rate during the VG SpaceShipTwo flight is 7.46 μSv for 1.22 h. This reveals that there is a very small radiation risk for the pilots and astronauts flying at the VG SpaceShipTwo up to 85.1 1 km altitude.

Experimental study on multi-point ignition of NH3/air by high-frequency nanosecond dielectric barrier discharge

Non-equilibrium plasma ignition technology, with its ability to expand ignition limits and increase ignition volume, is considered an important development direction of advanced ignition systems, and has significant advantages in improving ignition stability and combustion rate. This study investigates the ignition and combustion assistance effect of high-frequency nanosecond surface dielectric barrier discharge (nSDBD) on NH3/air mixture in a constant volume combustion chamber (CVCC). The study reveals the influence of high-frequency nSDBD on the growth process of the flame kernel in NH3/air mixture. As the discharge pulse number (PN) increases, the flame kernel develops from the middle position of the discharge filament to the head of the discharge filament, while there is no obvious flame at the root and middle of the discharge filament. Continuous discharge causes the flame kernel to appear concave and the center of the flame kernel to shift towards the wall of the CVCC. In the NH3/air mixture, the initial flame kernels exhibit dissipation phenomenon, resulting in a discrepancy between the number of initial flame kernels and the number of stable combustion flame kernels. As the discharge frequency or pulse number increases, and the number of stable combustion flame kernel increases. The adjustment of discharge frequency and pulse number can effectively control the flame development time (FDT) and flame rise time (FRT) of NH3/air mixture. As PN increases, both FDT and FRT are shortened. When discharge frequency is 20 kHz, the maximum shortening of FDT and FRT are 30 ms and 14 ms, respectively, about 55 % and 30 %. The effects of discharge frequency on FDT and FRT exhibit a non-monotonic variation pattern, and it is necessary to comprehensively consider various discharge parameters to achieve the best ignition effect. The ignition success rate curve of high-frequency nSDBD in NH3/air mixture is steep. The study results of this paper provide new discoveries and experimental data for advanced ignition systems.

Quantification of bedload transport in the Hungarian Danube using multiple analysis methods

While bedload transport is crucial to river morphodynamics, quantifying it in large rivers, such as the Danube, poses significant challenges. The current study focuses on the gravel-dominated section of the Danube River in Hungary, where multiple methods have been concurrently applied to evaluate bedload transport. In a representative cross section of the river, the following methods were applied: (i) point-wise direct physical sampling using a BfG-type pressure difference sampler, quality controlled with a video camera mounted on the sampler; (ii) indirect acoustic-based analysis with an Acoustic Doppler Current Profiler (ADCP), evaluating the Bottom Tracking signal; and (iii) indirect acoustic and imaging-based method utilizing Acoustic Mapping Velocimetry (AMV). The ADCP method is calibrated using results from the physical sampling, while the AMV method relies on bedform tracking and is entirely independent from the two other techniques. The results from a series of measurement campaigns, covering a wide range of flow regimes, suggest a robust bedload rating curve for the study section, enabling the estimation of bedload yields and its relation to morphological changes. In addition, the applicability conditions of the implemented methods are discussed.

Intercomparison of optical scattering turbidity sensors for a wide range of suspended sediment types and concentrations

To monitor the effects of rapid changes in climate and land use on sediment export from erodible environments, it is crucial to accurately quantify highly fluctuating suspended sediment concentrations (SSCs) in contrasted river systems that drain small to mesoscale catchments. To this end, we investigate the turbidity-based quantification of SSCs in the range of 0.05–100 g/L through laboratory experiments performed with 7 different types of turbidity sensors and sediments from 10 watersheds. We find that measurements of scattered light from multiple angles may allow for: (1) an extended monitoring range with SSCs up to 10–100 g/L, where enhanced uncertainty may occur near the transition in the effective operational ranges of the underlying signals (typically somewhere in the range of 1–10 g/L); and/or (2) a slightly reduced sensitivity to sediment properties. The specific turbidity of the investigated sensors is inversely related to particle diameter (D10) for SSCs up to 1–5 g/L. Backscatter and combined-signal sensors also show a dependency on sediment colour (CIE a∗), which becomes particularly prominent at SSCs above 10 g/L. We relate this increase in colour dependency with SSC to the expected effect of cumulative near-infrared light absorption associated with multiple scattering. We discuss covarying physical properties of naturally occurring river sediment that can dampen or enhance measurement sensitivity and result in turbidity-based SSC rating curves that may strongly differ in magnitude and form from curves derived for industrially prepared material that is often used for sensor calibration. Although the differences in SSC per sensor among sediment types are generally less than one order of magnitude, the systematic errors and uncertainties associated with high SSCs are typically greater than one order of magnitude and may disproportionally affect the quantification of sediment loads during large-magnitude flow events.

Parametric characterization of the Christopher–James–Patterson model for crack propagation in welded zone of A7N01 Aluminum alloys

AbstractAluminum alloy is a widely used material in railway vehicle structures. In order to accurately analyze the crack propagation mechanism of Aluminum alloy welding structures and predict their crack propagation life, this study focuses on the A7N01 Aluminum alloy and proposes a full‐field strain solution method based on the least‐squares method. For the first time, digital image correlation (DIC) experimental measurements are combined with the finite element analysis method to determine the shape and size of the plastic zone at the crack tip of the compact tension (CT) specimen. And it also calculates the crack propagation driving force parameters of the Christopher–James–Patterson (CJP) model using traditional crack propagation driving parameters. The research results revealed that the plastic zone at the crack tip captured by DIC experiments is in good agreement with the finite element simulation results. Additionally, the crack growth rate curve of the A7N01 Aluminum alloy, fitted based on the CJP model, is insensitive to the stress ratio. The results offer an effective approach to utilizing the da/dN‐∆KCJP curve in analyzing A7N01 Aluminum alloy and welded structural failures, broadening the scope of engineering applications for the CJP model.

Water Quality Assessment of the Euphrates River from Haditha to Al-Nasiriyah, Iraq

A comprehensive assessment of four gauging stations along the Euphrates River reach (Haditha, Al-Hindiya, Samawa, and Al-Nasiriyah) was conducted to assess the water quality deterioration spatially and temporarily for the period 2005-2021. The spotlight is on discharge rates and climate conditions, which mainly controlling water quality and availability. The mean monthly discharge rate was taken 2005–2021, in addition to the water quality parameters (TDS, pH, EC, Mg+2, Ca+2, Na+, SO4-2, Cl-, and HCO3-, BOD5, COD, FCB, and E. coli). The discharge rates showed a visible decrease downstream, causing the river salinity and all the ion concentrations to rise. The statistical package of social sciences revealed two groups of water pollution sources: The F1 reflects natural conditions produced from the dissolution of the basin rocks, with a percentage of 28.0% from the total variance; the eigenvalue is 4.4. F2 reflects the anthropogenic sources, contributing 14.5% and having an eigenvalue of 2.1. The total ionic salinity plot indicated less than 2000 mg/l at the Haditha and Al-Hindiya sites and between 3000 and 4000 mg/l at downstream sites (Samawa and Al-Nasiriyah). The transportation of dissolved loads is decreased downstream following the discharge rate as indicated by the rating curves, as follows: 781000, 542628.4, 443861, and 432950.4 tons/month for Haditha, Al-Hindiya, Samawa, and Al-Nasiriyah, respectively. Water type shows a notable downstream deterioration, from MgSO4 at Haditha and Na2SO4 at Al-Hindiya to NaCl at Samawa and Al-Nasiriyah sites.

Evaluation of proudP: A sound-based approach to uroflowmetry.

We sought to assess the performance of the proudP AI algorithm, integrated into a mobile application, in estimating uroflow curves and parameters using recorded urination sounds. A direct comparison was made between the peak flow rate (Qmax), voided volume, and uroflow curves predicted by the proudP algorithm and those obtained through established validation methods. A hardware uroflow simulator replicated uroflow profiles by precisely controlling water flow rates and extracting corresponding sound data. Ten uroflow profiles, representing typical patterns observed in male subjects, were selected. Simulation experiments with proudP were conducted using a standard toilet setup. The uroflow simulator was calibrated to reproduce uroflow profiles, and validation was performed against a Flowmaster uroflowmetry device. Statistical analysis included descriptive summaries, Bland-Altman analysis, and Concordance Correlation Coefficient (CCC) analysis. The proudP accurately captured various uroflow patterns generated by the simulator, with low standard deviations in Qmax predictions and biases near zero. The SDs of voided volume were slightly larger, primarily due to uroflow patterns with extended voiding times. The study validated the accuracy of proudP against in-office uroflowmetry, demonstrating robustness across different smartphone models. proudP proved to be as accurate as in-office uroflowmetry in estimating uroflow rate across various patterns. Its convenience in home monitoring offers patients a means to observe their urination patterns accurately, while enabling healthcare professionals to gain detailed insights remotely. proudP emerges as an essential solution for clinical practice and urological research.