HomeRadiologyRecently Published PreviousNext Reviews and CommentaryFree AccessImages in RadiologySpinal Hematoma Visualized with Dual-energy CT-derived Electron Density Overlay MapsChristian Nelles, Simon Lennartz Christian Nelles, Simon Lennartz Author AffiliationsInstitute for Diagnostic and Interventional Radiology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Kerpener Strasse 62, 50937 Cologne, Germany.Address correspondence to S.L. (email: [email protected]).Christian NellesSimon Lennartz Published Online:Apr 11 2023https://doi.org/10.1148/radiol.222680MoreSectionsPDF ToolsImage ViewerAdd to favoritesCiteTrack CitationsPermissionsReprints ShareShare onFacebookTwitterLinked In A 67-year-old man was admitted to the hospital with spontaneous, sudden-onset, severe thoracic back pain, radiating to the neck and lower back, accompanied by an episode of transient paraplegia of unknown severity, which lasted for 30–45 minutes. Three years prior, he had undergone mechanical aortic valve replacement with resection of an ascending aortic aneurysm associated with a bicuspid aortic valve. Consecutively, he had been treated with phenprocoumon for anticoagulation, with an international normalized ratio value of 4.5 at the time of admission (therapeutic range: 2.0–3.0). As the symptoms raised suspicion for aortic dissection, CT angiography of the chest and abdomen was performed with dual-layer dual-energy CT (dlDECT). dlDECT is a detector-based dual-energy CT technique in which a stacked scintillator registers lower energetic photons in the upper layer, whereas higher energetic photons are detected within the subjacent layer (1). The examination did not show signs of aortic dissection or other acute vascular pathologic conditions. Apart from persistent back pain, the patient’s symptoms receded. He was kept under surveillance for 3 days, after which worsening of the pain and the development of new high-grade paraplegia occurred, prompting an emergency MRI examination of the spine. The MRI scan showed extensive spinal hematoma, ranging from T1 to L1, with the maximum diameter and spinal cord compression at the level of T4-6 but without abnormal signal intensity of the spinal cord (Figure, A). The hematoma could not unequivocally be assigned to either the epi- or subdural space. Additionally, subarachnoid hemorrhage was noted along the cauda equina. The patient underwent successful emergency surgical evacuation of the hematoma, which during surgery showed extension to both the epi- and subdural as well as the subarachnoid space. Because digital subtraction angiography scans showed no vascular cause of the hematoma, spontaneous hemorrhage due to over-anticoagulation was determined as the most likely cause. After surgery, the pain and neurologic symptoms resolved rapidly, and the patient was discharged for subsequent rehabilitation. At retrospective review, different spectral data were reconstructed to determine if any of them might have facilitated earlier diagnosis of spinal hematoma with CT. Besides conventional images, virtual noncontrast and iodine images were also unremarkable. However, electron density overlay maps (Figure, B) clearly depicted the hematoma. The increased content of hemoglobin within the hematoma results in a higher material density at this location with a lesser effect on the average atomic number. There is only one study that showed that electron density maps may improve detection of prevertebral hematoma (2), which is in line with the finding in the case presented here. However, the application for detecting intraspinal hematoma has not been described yet. This might be a promising topic for systematic scientific evaluation, as electron density maps could improve CT-based detection of spinal hematoma in the emergency setting, potentially decreasing morbidity by enabling earlier treatment.(A) MRI scans of the spine in a 67-year-old man. Sagittal T2-weighted (top left) and T1-weighted (top right) images and axial contrast-enhanced, fat-saturated, T1-weighted image (bottom) show extensive spinal hematoma (arrows). The maximum diameter is located at the level of thoracic vertebrae T4-6 with effacement of the perimedullary cerebrospinal fluid and spinal cord compression. (B) Dual-layer dual-energy CT reconstructions show the corresponding CT angiography scans of the chest. Electron density overlay images (left) clearly depict the hematoma (green; arrows) that is protruding in the spinal canal. Conventional images (right) in the sagittal and axial plane. The hematoma is almost entirely imperceivable (arrows).Download as PowerPointOpen in Image Viewer Disclosures of conflicts of interest: C.N. No relevant relationships. S.L. Senior deputy editor for Radiology In Training; member of the Radiology editorial board.
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