High-resolution 3-dimensional photography offers unparalleled advantages in objective and detailed skin contour characterization, quantification, volumetric and surface area analysis. This study aims to illustrate the benefits of 3-dimensional photography through analysis of noninvasive reduction of submental fat using cryolipolysis. A nonrandomized prospective analysis was performed of 14 selected patients who underwent treatment with cryolipolysis (CoolSculpting System; Zeltiq) between February and June 2016. The benefits of 3-dimensional photography (Vectra; Canfield Scientific) are presented. High-quality 3-dimensional images are presented to illustrate the utility of 3-dimensional photography as a means to quantitatively evaluate changes in submental volume, fat thickness, and surface area reduction, thereby exemplifying the broad applicability of this imaging technique. Three-dimensional photography technology provides clinicians with enhanced options that extend beyond simple 2-dimensional photography. Our study illustrates the benefits of the technology for accurately measuring volumetric changes after submental cryolipolysis treatment.