Clinical Efficacy of Fat Reduction on the Thigh of Korean Women through Cryolipolysis

Abstract

A variety of techniques such as surgical, pharmacological and electrical as well as manipulation approaches had been tried in order to remove undesirable fat on targeted area. So far, no distinguished method is considered to be most cost effective. Cryolipolysis is a new concept to reduce fat since Zeltiq machine had been introduced several years ago. Zeltiq machine, invented by Manstein Dieter, a researcher of photo-medicine group, is used to remove fat through cryolipolysis. Previous studies showed Zeltiq had a pronounced outcome to eliminate central abdominal fat in pig as well as human. Until now, no investigation was done to remove fat in human thigh lesion. Therefore, this study is conducted to investigate the clinical efficacy and safety of cryolipolysis on fat removal of thigh through cryolipolysis. Fourteen healthy premenopausal volunteered women had been conducted to assess their anthropometrical, social, and cardio-metabolic, and femoral fat amount by computer tomography, and adverse events at initial, 4 week, 12 week visit. There was no significant difference of measured fat amounts between cryolipolysis and frequency electrical treatment for 12 weeks. Minor adverse events such as pain (26.67%), bruise (20%) and numbness (20%) were noted. In conclusion, there was no difference in efficacy in removal of local fat on thigh by cryolipolysis through Zeltiq machine. Cryolipolysis was found to be safe for 12 week clinical trial.