An expanding body of evidence from a variety of sources has highlighted the significant mortality associated with high-risk major surgery. Increasingly we are able to identify patients who, due to a combination of the severity of the surgery they undergo and their pre-operation physiological condition, have a significantly higher, quantifiable risk of death and major morbidity. At the same time an increasing number of clinical trials have demonstrated that peri-operative manipulation of patient's physiology can reduce the mortality and morbidity associated with high-risk major surgery. However, it is also clear that clinical practise is not changing to reflect the availability of this information. Why is this? The Consensus Meeting at Christ's College, Cambridge, was convened to bring together interested parties, including patients representatives, surgeons, anaesthetists, critical care physicians and managers, to address the question posed above. The conference was planned to consider the evidence in support of the assertions that high-risk surgical patients exist and that their outcome after surgery can be improved. The meeting was designed to allow the parties involved to assess the data presented in an unbiased way under the control of a distinguished lay chairman. A panel comprising representatives from each group present (see Table 1 ) were charged with producing an independent consensus statement at the conclusion of the proceedings under the supervision of the conference chairman. Additionally it was hoped that the meeting would raise the profile of this field of work, serve as a forum to discuss the best ways to take it forward and influence clinical practise if appropriate. After a brief introduction, the following presentations were given. Each presentation was followed by a period of questioning from the panel then opened out to include the audience.
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