Appraisal Criteria Research Articles

More than cost-effectiveness? Applying a second-stage filter to improve policy decision making.

BackgroundApart from cost‐effectiveness, considerations like equity and acceptability may affect health‐care priority setting. Preferably, priority setting combines evidence evaluation with an appraisal procedure, to elicit and weigh these considerations.ObjectiveTo demonstrate a structured approach for eliciting and evaluating a broad range of assessment criteria, including key stakeholders’ values, aiming to support decision makers in priority setting.MethodsFor a set of cost‐effective substitute interventions for depression care, the appraisal criteria were adopted from the Australian Assessing Cost‐Effectiveness initiative. All substitute interventions were assessed in an appraisal, using focus group discussions and semi‐structured interviews conducted among key stakeholders.ResultsAppraisal of the substitute cost‐effective interventions yielded an overview of considerations and an overall recommendation for decision makers. Two out of the thirteen pairs were deemed acceptable and realistic, that is investment in therapist‐guided and Internet‐based cognitive behavioural therapy instead of cognitive behavioural therapy in mild depression, and investment in combination therapy rather than individual psychotherapy in severe depression. In the remaining substitution pairs, substantive issues affected acceptability. The key issues identified were as follows: workforce capacity, lack of stakeholder support and the need for change in clinicians’ attitude.ConclusionsSystematic identification of stakeholders’ considerations allows decision makers to prioritize among cost‐effective policy options. Moreover, this approach entails an explicit and transparent priority‐setting procedure and provides insights into the intended and unintended consequences of using a certain health technology.Patient contributionPatients were involved in the conduct of the study for instance, by sharing their values regarding considerations relevant for priority setting.

AB0908-HPR SIGNED, SEALED, DELIVERED: PHARMACISTS ACHIEVING BETTER CARE CLOSER TO HOME IN RHEUMATOLOGY HIGH COST DRUG MANAGEMENT DURING THE COVID-19 PANDEMIC

Background:The Pharmacy High Cost Drug (HCD) and Homecare (HC) team, based at a large acute teaching hospital consists of a range of skilled pharmacists, technicians and administrative staff. The team act as a HCD liaison between the hospital and commissioners, working closely with an expanding variety of specialist clinical teams to manage prescription processing for the following patient groups; HC: 2238; Hospital FP10: 1060; Outsourced Subsidiary Pharmacy Model: 41. HCD management, particularly immunosuppressive biologic therapies for complex rheumatology conditions such as rheumatoid arthritis, has been challenging during the Covid-19 pandemic. The inelasticity in demand for better care closer to home and a functional Integrated Care Records system has intensified, as many patients are now shielding/self-isolating at home.1 Frugal innovations have been key during this time – achieving value and simplicity in service re-design to deliver better patient care.Objectives:This review explores the support provided by the Pharmacy HCD and HC team to the rheumatology service since March 2020 to aid in service improvements during the pandemic.Methods:The Pharmacy HCD and HC team reviewed existing practice to better respond to the service changes required during the pandemic in regard to the following areas; identifying patients for Covid-19 shielding; responding to changes in HC service provision; communication with commissioners; remote staff working; reviewing HCD formulations and administration routes; changes in commissioning arrangements.Results:i) Rapid development of patient datasets following identification of 1,623 immunosuppressive drug entries in line with BSR Covid-19 guidance (first published in March 2020), thus enabling social distancing/shielding guidance to be issued to patients via letters/virtual platforms.2 ii) Swift re-routing of urgent new biologic HC registrants to a new hospital pharmacy home delivery provision when certain HC providers temporarily imposed restrictions on intake of new registrants. This hospital initiative was further enhanced to a hub and spoke model enabling patients to have easy access to their medications from their nominated local community pharmacy branch. iii) Providing assurance to commissioners that clinical follow up reviews could continue virtually, blood samples could be taken at an external hub and blueteq documentation would be completed covering NICE technology appraisal (TA) criteria. iv) A successful pilot utilising the lean PDSA (Plan, Do, Study, Act) quality improvement methodology, to enable remote working pharmacists and technicians to process HC prescriptions remotely in the absence of an electronic prescribing and medicines administration system. v) Reviewing potential plans to switch certain hospital day-case intravenous biosimilar infusions such as infliximab to subcutaneous administration via HC. vi) Business contingency development plans to protect fragile medication supply chains. vii) Clarifying implications for changes in contracting and payment arrangements announced by NHS England and NHS Improvement due to the pandemic.3Conclusion:In summary, the role of the HCD Pharmacists during the pandemic in supporting rheumatology patients and the multidisciplinary team has been fundamental; ensuring signed prescriptions are securely processed to safely deliver medication to those in need.

Sexual Behavior Problems in Adolescents with Intellectual Disabilities: A Systematic Review

BACKGROUND: Several studies conducted on adolescents with intellectual disabilities (ID) have reported various problems of sexual behavior that occurs in the group, including HIV-related risky sexual behavior and other health-related concerns. AIM: This review aims to synthesize studies on the problems regarding sexual behavior in adolescents with ID to obtain data on the types of risky sexual behavior problems. MATERIALS AND METHODS: Synthesis was conducted on nine studies of children aged 10–20 years old with intellectual disabilities as subjects who have no other psychiatric comorbidities and met the appraisal criteria based on the checklist for analytical cross-sectional studies of the Joanna Briggs Institute (JBI). RESULTS: Several behaviors were found in the group of adolescents with ID. Masturbation is the type of solitary behavior that appears the most, besides other behaviors like touching genitals and getting naked in public places. Sexual intercourse is the most widely reported in the type of “involving other persons.” Sexual intercourse with more than 1 person without using contraception to protect against sexual transmitted disease (STD) is at risk for HIV infection or other infectious diseases. CONCLUSIONS: The results of this review have indicated that adolescents with ID have sexual needs and experience sexual behavior problems similar to ordinary adolescents in general. They actually have a higher risk for having risky sexual behavior because they lack understanding of sexuality. These findings emphasize the need for sex education so that young people with disabilities can have healthy sexual behavior and a safe life.

The role of undergraduate laboratories in the formation of engineering identities: A critical review of the literature

Background: There was growing recognition worldwide by professional engineering bodies, engineering faculties and researchers on the need to pay attention to engineering students’ emerging identities and how they were formed across the trajectory of undergraduate engineering programmes. An increasing number of research studies focused on engineering identity, including systematic reviews of the research literature.Aim: Engineering laboratories were key learning spaces in undergraduate engineering programmes. In the laboratory, students learned to integrate theory and practice, engaged in problem-solving and applied experimental methods. The purpose of this critical review of the literature was to interrogate the impact that learning in engineering laboratories had on emerging professional identities across engineering disciplines and fields.Method: This review built on and extended previous systematic reviews on engineering identity by studying pedagogies in the engineering laboratory through the lens of identity formation. Search terms were consistently applied to eight databases, which yielded 57 empirical studies, after the application of relevance and quality appraisal criteria. Two reviewers independently applied a socio-materialist theoretical framework of identify formation to each study and coded each of the studies into categories aligned with the theoretical framework.Results: The findings of the critical review revealed the temporal, spatial, material, performative and discursive dimensions in engineering identity formation and showed that students’ emerging identities could be affirmed and supported by appropriate laboratory pedagogies.Conclusion: The critical review of the literature concluded that curricular and pedagogical interventions that were better aligned with the dimensions of identity formation were more likely to enhance students’ identification with engineering.

Culture and performance appraisal in multinational enterprises: Implementing French headquarters' practices inMiddle East and North Africasubsidiaries

AbstractPerformance appraisal requires interactions between managers and employees and as such can be highly sensitive to differences in cultural values. This can be challenging when multinational enterprises (MNEs) are active across different institutional contexts, particularly when operating in the culturally complex Middle East and North Africa (MENA) region. In this qualitative study, we apply institutional theory to explore how performance appraisal practices are implemented and internalized in MNE subsidiaries in the MENA region through manager–employee interactions. A total of 117 interviews were conducted with different headquarter and subsidiary stakeholders (managers and employees) of four French MNEs operating in Lebanon and Tunisia. The findings indicate that, during implementation, performance appraisal criteria, evaluation, and feedback were adapted based on socio‐cultural values to achieve internalization. Such values include the emotional relationship between managers and employees, the fear of losing face, high power distance, the desire to avoid confrontation, and high‐context communication. Insights for future research are presented regarding the viability of MNEs operating in the MENA region implementing corporate performance appraisal practices.

Design of DSS The Best Employee Performance Using Analytical Hierarchy Process UML Based

Employees are a highly needed human resource. In order to achieve the desired goals, the agency conducts the best performance appraisal of employees. The Analytical Hierarchy Process method is a method for determining criteria and choice alternatives, followed by calculating the eigenvector value and testing its consistency. The application of analytical hierarchical analysis of the best employee performance appraisal process, where the results of this assessment can encourage every employee to give the best performance to the agency. The best employee performance decisions are made at the ambalutu village hall office. There are several criteria for performance appraisal, namely communication skills, honesty, cooperation, and person. Analysis method analytical hierarchy process where each criterion will be assessed in pairs comparison with other criteria to get priority value. In this study the results of the ratio were 0.07, which means that the assessment was consistent because it was less than 0.1, so the percentage of communication values was 40%, honesty 34%, cooperation 17% and personal 10%.

Secretory products of the corpus luteum and preeclampsia.

Despite significant advances in our understanding of the pathophysiology of preeclampsia (PE), there are still many unknowns and controversies in the field. Women undergoing frozen-thawed embryo transfer (FET) to a hormonally prepared endometrium have been found to have an unexpected increased risk of PE compared to women who receive embryos in a natural FET cycle. The differences in risk have been hypothesized to be related to the absence or presence of a functioning corpus luteum (CL). To evaluate the literature on secretory products of the CL that could be essential for a healthy pregnancy and could reduce the risk of PE in the setting of FET. For this review, pertinent studies were searched in PubMed/Medline (updated June 2020) using common keywords applied in the field of assisted reproductive technologies, CL physiology and preeclampsia. We also screened the complete list of references in recent publications in English (both animal and human studies) on the topics investigated. Given the design of this work as a narrative review, no formal criteria for study selection or appraisal were utilized. The CL is a major source of multiple factors regulating reproduction. Progesterone, estradiol, relaxin and vasoactive and angiogenic substances produced by the CL have important roles in regulating its functional lifespan and are also secreted into the circulation to act remotely during early stages of pregnancy. Beyond the known actions of progesterone and estradiol on the uterus in early pregnancy, their metabolites have angiogenic properties that may optimize implantation and placentation. Serum levels of relaxin are almost undetectable in pregnant women without a CL, which precludes some maternal cardiovascular and renal adaptations to early pregnancy. We suggest that an imbalance in steroid hormones and their metabolites and polypeptides influencing early physiologic processes such as decidualization, implantation, angiogenesis and maternal haemodynamics could contribute to the increased PE risk among women undergoing programmed FET cycles. A better understanding of the critical roles of the secretory products of the CL during early pregnancy holds the promise of improving the efficacy and safety of ART based on programmed FET cycles.

Employee Performance Apparaisal Using Decision Support System by AHP and TOPSIS Methods

During this time the performance appraisal of PT. Injep Inti Cemerlang has not been implemented optimally, especially in employee performance appraisal. Performance appraisal so far is only determined from the results, there are no clear appraisal criteria. Based on this reason, a decision support system is needed to help find the best alternative for the employees selection. In this research a decision support system for employee performance appraisal will be developed based on Attitude, Responsibility, Attendance, Discipline and Collaboration. This research aims to design a decision support system for employee performance appraisal using data collection methods by observation, interviews and giving questionnaires to employees of PT. Injep Inti Cemerlang. The data collected is carried out the process of analyzing data and looking for weighting values using the AHP method and for ranking using the TOPSIS method, where each criterion is appraisal factors and alternatives in this case employees are compared the criteria that have been weighted through the process of calculating the AHP and TOPSIS method starting from giving the weighting of criteria by calculating with Ms. Excel and calculating with Expert Choice software. The results have been obtained from weighting the next ranking by the TOPSIS method. thus providing a value output that results in a system that employees appraisal. This decision support system helps the employee performance apprasial at PT. Injep Inti Cemerlang in determining the employee who has the best performance

Frequency of examination and perceived contribution of factors relating to work-related musculoskeletal disorders of physiotherapists

Objective. Literature confirms that many physiotherapists suffer from work-related musculoskeletal disorders (WMSDs), but studies mention different, complementary and contradictory findings regarding risk factors. This scoping review aimed at revealing the most frequently examined and contributory WMSD factors mentioned in recent studies about physiotherapists. Methods. Based on specific inclusion/exclusion and appraisal criteria, 11 studies published between 2012 and 2018 were included in the analysis. The factors recorded per publication were grouped into 18 categories, the frequency of their appearance across the sources was counted and the median ranks of their relative reported contribution were calculated. Results. Excessive workload was found to be the most contributory factor, followed by the application of manual orthopaedic techniques. However, demanding and repetitive manual tasks were the most common factors investigated in the publications reviewed. A medium-strength correlation was found between the frequency of examination and reported contribution of factors but with a noticeable range of the confidence interval possibly due to the diversity of the approaches in the studies reviewed. Conclusions. The findings indicate a relative discordance between the level of contribution of each factor to the development of WMSDs and the types of factors most frequently addressed by studies.

Banović Strahinja između pesme i filma

This paper brings insight into the content and analysis of the screenplay "Soko" (The Hawk) (1977) which Saša Petrović (1929-1994) created according to the epic folk song "Banović Strahinja". Critical approaches to adaptations are numerous and varied, and in this paper we rely on newer theories (Robert Stam, Linda Hutcheon, Dudley Andrew, David Krantz, Thomas Leitch, Sarah Cardwell...) which perceive the adaptation for other media as an autonomous work of equal status as the original work and which reject fidelity to the original as the criteria for appraisal of adaptations. The comparative approach in this paper was used to see the way in which the narrative, thematic and aesthetic elements were created for the needs of the new media. In addition to the analysis of literary segments, we have included the analysis of film, intertextual and contextual elements, which we considered relevant for the interpretation and assessment of the adaptation. Petrović is a director who, although he made famous his country's cinematography in the world, did not receive the opportunity to record this film. Special attention in this paper is dedicated to the scene within the tent of the Vlah Alija and the scene with the wolves, and both of them conform to the Genet's notion of paraleptic continuation, which illustrate Petrović's creative manner in the process of adaptation of the literary work.

Appraisal criteria of history project activity of pupils at school and in a museum

Appraisal criteria of history project activity of pupils at school and in a museum

An integrative literature review on intimate partner violence against women in South Korea.

PurposeThe purpose of this study was to analyze and synthesize the literature on intimate partner violence (IPV) against women in South Korea. MethodsWhittemore and Knafl’s integrative review method was used. Studies in English and Korean were searched in seven electronic databases using the following combination of terms: “Korea,” “females or women or girls,” “intimate partner violence or domestic violence or domestic abuse.” ResultsTwenty-five studies were ultimately selected, all of which met the quality appraisal criteria with a grade of medium or higher, using Gough’s weight of evidence. IPV was divided into marital violence and dating violence. Factors related to IPV were classified into intrapersonal, interpersonal, and social factors, and these three factors were linked together. Intrapersonal factors included general characteristics, perceptions, attitudes, psychological factors, and violent experiences. Interpersonal factors involved relationships with parents and partners. Finally, social factors and attributes were integrated into social support and influences on life.ConclusionIn order to minimize and prevent harm to women from IPV when caring for women who experienced IPV, multiple factors should be considered. Specifically, general and psychological characteristics, perceptions and attitudes toward IPV, relationships with families and partners, and available social support systems and resources should be considered. Moreover, these findings will be helpful for assessing women or providing interventions for victims of violence. Finally, more diverse IPV studies should be conducted by nurses in the future.

A multicriteria approach for rating investments in commercial real estate

AbstractThe commercial real estate (CRE) sector concerns a diverse set of actors that specialize in real estate activities, such as brokerage, valuation, construction, and asset management. CRE activity is a key indicator for the level of corporate growth and the economic development of a country. However, investments in CRE face a volatile global environment, which is characterized by deep uncertainties and cyclical behavior. In this context, decision support tools that facilitate the monitoring and assessment of CRE investments are of major importance for various stakeholders, including investors and policy makers. The objective of this study is to present a comprehensive approach for assessing CRE investments based on a multicriteria evaluation framework. The analysis is based on a sample of commercial assets taken from the portfolio of a real estate investment company in the United States. The proposed multicriteria approach considers a rich set of evaluation criteria, including macroeconomic indicators, information about the local CRE markets, as well as the characteristics of the assets under consideration. Using analytical methodologies from the family of ELECTRE outranking methods, the assets are ranked and rated according to their overall performance. Different scenarios are explored for the weightings of the appraisal criteria, thus enabling the analysis of the robustness of the results.

PNS188 MULTI-Criteria Decision Analysis on the Inclusion of Orphan Drugs for Reimbursement in Bulgaria, France, Germany, Sweden, UK: A Comparative Analysis

The objective of this study is to identify, describe, analyze & compare the main criteria in appraising medicines for rare diseases (RD) – Bulgaria vs. France, Germany, Sweden, UK. This study demonstrates some of the main differences and similarities in the HTA appraisal for orphan drugs across the selected countries. A comparative analysis of published regulatory requirements & appraisal criteria by HTA bodies for RD medicines was conducted for Bulgaria, France, Germany, Sweden, UK. The choice of countries is made due to a mandatory requirement in Bulgaria for at least one positive opinion by an HTA body from the selected countries as a condition for HTA approval. Bibliographic databases, the Internet and government/HTA organization websites were searched. The collected data was synthesized in Excel, qualitative comparative analyses were performed. Five key domains were analyzed and compared: special HTA appraisal process for orphan drugs and medicines for RD, clinical effectiveness, cost-effectiveness and budget impact, moral and ethical considerations. Almost all countries have multiple criteria for HTA appraisal of orphan drugs. All of them except Bulgaria have special HTA process for orphan drugs and RD. Almost all of them typically require clinical assessment, cost-effectiveness, and budget impact analysis (BIA). However, BIA is not taken into account in committee's considerations in the UK (only value is). Moral and ethical aspects are an additional criterion considered only in Bulgaria. Results presented in table. This study demonstrates that HTA process for orphan drugs and RD typically require similar criteria as drugs for common conditions. However, specific submission requirements could be beneficial for a faster, and more transparent decision-making by national authorities. When comparing with countries which require different criteria for HTA appraisal, the moral and ethical considerations In Bulgaria seem neglected.

PRO98 Country Specific Approaches to Appraising RARE Disease Treatments: A Case Study Analysis of the IMPACT of Different Processes

Rare disease treatments (RDTs) often pose challenges to standard appraisal and reimbursement processes. Countries vary in their approaches to appraising RDTs; some use different ‘supplemental’ processes, others use standard processes. This study examines the impacts of these different appraisal processes for two RDTs in selected countries. Literature Review and Synthesis. A case study analysis was conducted on countries with different types of appraisal processes. Country selection was based on availability of public health technology assessment (HTA) reports and representative countries with various processes for appraising RDTs. Two contrasting RDTs were chosen according to the criteria rare/ultra-rare treatment, affecting child/adult, and life-threatening/disabling. Information for each country's RDT appraisal was extracted into templates to enable comparison of appraisals across countries, and evaluation of the impact of the different processes in practice. Reports from Belgium, England, France, Germany, U.S., Italy, Netherlands, Norway, Scotland, Sweden and the U.S. were selected for Nusinersen and Voretigene. Characteristics of each country's process were identified, including information related to evidence submitted and committees’ interpretation of it. Uncertainties raised did not vary between the two treatments and did not seem to depend on the type of appraisal process. Additional considerations beyond clinical and cost effectiveness were seen for both drugs. For Nusinersen, more countries with supplemental processes took into account the impact on QoL than countries with standard processes, while for Voretigene, more countries with supplemental processes took into account severity, rarity and unmet need than countries with standard processes. While acceptance of uncertainty and additional considerations existed within both standard and supplemental processes, countries with supplemental processes more often referred to formal criteria for these considerations. The formal criteria for RDT appraisal within supplemental approaches may make them more appropriate to facilitate consistent decision-making and management of RDT challenges.

Regression Discontinuity Designs in Health: A Systematic Review.

Regression discontinuity designs are non-randomized study designs that permit strong causal inference with relatively weak assumptions. Interest in these designs is growing but there is limited knowledge of the extent of their application in health. We aimed to conduct a comprehensive systematic review of the use of regression discontinuity designs in health research. We included studies that used regression discontinuity designs to investigate the physical or mental health outcomes of any interventions or exposures in any populations. We searched 32 health, social science, and gray literature databases (1 January 1960 to 1 January 2019). We critically appraised studies using eight criteria adapted from the What Works Clearinghouse Standards for regression discontinuity designs. We conducted a narrative synthesis, analyzing the forcing variables and threshold rules used in each study. The literature search retrieved 7658 records, producing 325 studies that met the inclusion criteria. A broad range of health topics was represented. The forcing variables used to implement the design were age, socioeconomic measures, date or time of exposure or implementation, environmental measures such as air quality, geographic location, and clinical measures that act as a threshold for treatment. Twelve percent of the studies fully met the eight quality appraisal criteria. Fifteen percent of studies reported a prespecified primary outcome or study protocol. This systematic review demonstrates that regression discontinuity designs have been widely applied in health research and could be used more widely still. Shortcomings in study quality and reporting suggest that the potential benefits of this method have not yet been fully realized.

Computational and experimental evaluation of view out according to European Standard EN17037

This paper presents an experimental evaluation of view out based on EN17037:2018 Daylight in Buildings within an educational building. The primary motivation to conduct the research was an introduction of a view out appraisal criteria by the mentioned standard. The study gives insights into the following: (i) the use of computational evaluation of an outside view according to the EN17037 criteria (ii) the use of the direct simultaneous questionnaire to assess the view out (iii) a description of the relationships between the normative criteria and users' subjective assessments of view out, and (iv) the link between the quantitative and qualitative parameters of the evaluation of view out. The study was conducted using a three step approach: S1 – a computational evaluation of the outside view according to the standard's recommendations: distance to the nearest obstacle, number of visible layers and angle of the view; S2 – a view out evaluation based on a direct questionnaire in the selected indoor spaces under various daylight conditions; S3 – analysis and comparison of the results. The data was collected in 2019 and 2020 with 169 evaluations from volunteering architecture students. The key findings are: (i) the outcome of the subjective participants' evaluation of the view out differs from the results generated through computational simulations based on the EN17037 ratings (ii) similar results were recorded in reference to the estimation of the layers of the view, and (iii) the responders rated the view out one rank lower than the computational evaluation suggests.

Employees of Greatness: Signifying Values in Performance Appraisal Criteria

The spread of performance-based and variable pay systems has affected expectations on employee contributions and remuneration, which have become increasingly personalized and individualized. Based on a theoretical valuation studies approach, this study of performance-based pay systems in Sweden shows that performance appraisals are (e)valuations of employees’ yearly performance in which they are prized and (ap)praised at the same time. Through a document analysis of performance criteria from four organizations, the study analyzes how values expressed refer to Boltanski and Thévenot’s six orders of worth. The analysis resulted in a theoretical construction of a joint ideal of Employees of Greatness, against which employees are measured and remunerated. The existence of the ideal of employee greatness is explained by the increasing congruence of organizational ideals in private and public sectors, as principles from emotional and cognitive forms of capitalist organization are superimposed on traditional industrial capitalist organizational ideals.

Problems and Challenges: A Private Forest Purchase Method for National Forest Expansion in South Korea

This study analyzes the appraisal procedure for government purchasing of privately-owned forests in Korea, in terms of current status, existing procedures, and appraisal cases. The method is a widely conducted instrument of national forest expansion policy. For the purchase status, the purchase targets of private forests, unit price, and purchase records are analyzed. The purchase procedure is to analyze the process from the sale agreement submission of the owner to the transfer of ownership after completion of sales. The appraisal cases analyze the appraisal results according to the actual purchase of private forests. Three of the procedure’s most problematic aspects are identified: The selection of appraisal companies, the failure to include the value of standing trees, and ambiguities in appraisal criteria. The study suggests some ways of improving the continuing implementation of the national forest expansion program through ongoing purchases of privately-owned forests. Firstly, the selection process for appraisal companies needs to be improved by independent third-party institutions or a competitive bidding system. Secondly, since forests are classified into standing trees and forest land, these two categories need to be appraised separately rather than together, as is often currently the case. Thirdly, since appraisal factors are currently based primarily on appraisers’ subjective experience and knowledge, there is a need both for developing more objective appraisal criteria as well as for improving the training of appraisers themselves, to increase their level of expertise and ensure greater objectivity in forest appraisal.

Mortality and its association with CD4 cell count and hemoglobin level among children on antiretroviral therapy in Ethiopia: a systematic review and meta-analysis

BackgroundEven though there are advancements in HIV/AIDS prevention and treatment approach, HIV continues to be a global challenge. Pediatrics HIV is one of the challenges in the reduction of child mortality particularly in less developed countries like Ethiopia. Therefore, this study aims to estimate the pooled proportion of child mortality and the effect of hemoglobin level and CD4 cell count among children on antiretroviral therapy in Ethiopia.MethodAll published were articles searched using PubMed, EMBASE, Google Scholar, and Web of Science database. Besides, Ethiopian institutional research repositories and reference lists of included studies were used. We limited the searching to studies conducted in Ethiopia and written in the English language. Studies that were done in a cohort, cross-sectional, and case-control study design were considered for the review. The weighted inverse variance random effects model was applied, and the overall variations between studies were checked by using heterogeneity test Higgins’s (I2). Subgroup analysis by region and year of publication was conducted. All of the included articles were assessed using the Joanna Briggs Institute (JBI) quality appraisal criteria. In addition, publication bias was also checked with Egger’s regression test and the funnel plot. Based on the results, trim and fill analysis was performed to manage the publication bias.ResultA total of 16 studies with 7047 participants were included in this systematic review and meta-analysis. The overall pooled proportion of mortality among children on antiretroviral therapy (ART) was found to be 11.78% (95% CI 9.34, 14.23). In subgroup analysis, the highest child mortality was observed in the Amhara region 16.76 % (95% CI 9.63, 23.90) and the lowest is in the Tigray region 4.81% (95% CI 2.75, 6.87). Besides, the proportion of mortality among children with low CD4 count and hemoglobin level was 2.42 (AOR = 2.42, 95% CI 1.65, 3.56) and 3.24 (AOR = 3.24, 95% CI 1.51, 6.93) times higher compared to their counterparts, respectively.ConclusionThe proportion of mortality among children on ART was high in Ethiopia. Those children who had low CD4 cell count and low hemoglobin levels at baseline need special attention, treatment, and care.Trial registrationThe protocol of this systematic review and meta-analysis has been registered in PROSPERO with the registration number CRD42018113077.