To explore the design method of museum cultural and creative products based on multi sensory experience, improve product level and user experience, and provide new directions for the development of museum cultural and creative design. The method first introduces the cognitive principles and sensory expression methods of sensory experience, and then focuses on the study of three common multi sensory phenomena: multi sensory integration, synesthesia, and sensory compensation. It analyzes their application in the design of cultural and creative products, summarizes the transformation process of user generated multi sensory experience, and establishes a multi sensory experience cultural and creative product design process based on this. Conclusion: Product design with multi sensory experience can bring users a more comprehensive and profound experience, help promote the inheritance and development of museum culture, and improve the serious problem of homogenization in the cultural and creative industry.