For radio-based time-of-arrival (TOA) positioning systems applied in harsh environments, obstacles in the surroundings and on the vehicle itself will block the signals from the anchors, reduce the number of available TOA measurements and thus degrade the localization performance. Conventional multi-antenna positioning technique requires a good initialization to avoid local minima, and suffers from location ambiguity due to insufficient number of TOA measurements and/or poor geometry of anchors at a single epoch. In this paper, taking advantage of the multi-epoch and multi-antenna (MEMA) TOA measurements bridged by inter-epoch constraints to utilize more information and improve the geometry of visible anchors, we propose a new positioning method, namely MEMA-TOA method. A new initialization method based on semidefinite programming (SDP), namely MEMA-SDP, is first designed to address the initialization problem of the MEMA-TOA method. Then, an iterative refinement step is developed to obtain the optimal positioning result based on the MEMA-SDP initialization. We derive the Cramér-Rao lower bound (CRLB) to analyze the accuracy of the new MEMA-TOA method theoretically, and show its superior positioning performance over the conventional single-epoch and multi-antenna (SEMA) localization method. Simulation results in harsh environments demonstrate that i) the new MEMA-SDP provides an initial estimation that is close to the real location, and empirically guarantees the global optimality of the final refined positioning solution, and ii) compared with the conventional SEMA method, the new MEMA-TOA method has higher positioning accuracy without location ambiguity, consistent with the theoretical analysis.