Experimental and analytical evidence for the influence of applied stress, crack length, and stress intensity factor on crack closure is critically compared and evaluated. Fatigue crack opening behaviors are broadly catalogued into three classes. Class I comprises “near-threshold” behavior, where crack closure levels increase with decreasing stress intensity factor. In class II, the “stable” regime, the crack opening level is independent of the stress intensity factor and crack length but is influenced by the applied stress. Class III is characterized by the loss of elastic constraint accompanying extensive yielding at the crack tip or in the remaining ligament, especially with further crack growth. Here, the crack opening level decreases with increasing crack length until little or no closure occurs. These three different classes of closure behavior are extensively illustrated with both experimental data and the results of numerical closure simulations, particularly original finite element (FE) analyses. No single relationship between crack opening levels and the fundamental fatigue parameters is found to hold universally, due to the wide range of mechanisms which cause or influence closure.