Since entering the 13th Five-Year Plan construction, the state has actively promoted the development and construction of education informatization, encouraged teachers to use information technology to innovate teaching models, update teaching concepts, and improve teaching quality to cultivate talents that meet the needs of the society in the new era. The mixed teaching mode combines the advantages of traditional teaching methods with the advantages of networked teaching. It not only plays the leading role of teachers in guiding, enlightening, and monitoring the teaching process, but also fully reflects the initiative and creativity of students as the main body of the learning process. This article analyzes the current teaching situation of international business courses in application-oriented universities, and explores the implementation strategies of a hybrid teaching model combining classroom teaching and online teaching. It will analyze four aspects from self-learning before class, internalization of knowledge in class, online consolidation after class and the assessment system, and provide references for the application of mixed teaching model in business courses.