Renewable heating and cooling systems are regarded as appealing technologies to alleviate energy crises and environmental pollution. An integrated life cycle environmental and Comprehensive Life Cycle Cost (CLCC) method has been proposed and applied to assess the environmental and economic performance of five renewable heating and cooling technologies (RCHTs) for the first time, including Ground Coupled Heat Pump (GCHP), Hybrid Ground Coupled Heat Pump (HGCHP), River Source Heat Pump (RSHP), Air Source Heat Pump (ASHP), and Building Cooling Heating and Power fueled by Biomethane (BCHPB) systems. The results showed the BCHPB system exhibited optimum environmental performance in a commercial building, while the comprehensive environmental impact index of RSHP, HGCHP, GCHP, and ASHP systems were decreased by 24%, 21%, 14%, and 4% as compared to the baseline system. The RSHP system had the lowest comprehensive economic cost of 60.1 CNY/m2, followed by HGCHP (63.9 CNY/m2), ASHP (66.4 CNY/m2), BCHPB (80.0 CNY/m2) and GCHP systems (82.8 CNY/m2). When considering the economic costs and environmental impacts, the eco-efficiency of the RSHP system was increased by 36.7%, 65.5%, 88.4%, and 161.5% compared to HGCHP, ASHP, BCHP, and GCHP systems. In addition, biomethane prices and variable electricity mix significantly affect the environment and financial results.