Introduction Recent studies showed equivalent dose at a depth of 0.07 mm, Hp (0.07) to be adequate in some cases to monitor the eye lens in interventional radiology, instead of equivalent dose at a depth of 3 mm, Hp (3). Purpose The aim of this study was to investigate by Monte Carlo calculations the dose deposition within the eye lens and contribute to the choice of the appropriate dose quantity. Materials and methods The XRayImagingSimulator was used to model the patient, the operator and the interventional diagnostic unit as well as to calculate the dose within the operators eyes by use of Monte Carlo techniques. Eye lens were placed in three different depths within the eye: 2.3 mm, 3.3 mm, 4.3 mm, representing mean depth and the limits found in a normal adult population. The primary spectra were calculated for 70 kV tube voltage, 12° tungsten target, 3 mm aluminum inherent filtration with an additional copper filtration (0.1 mm, 0.3 mm, 0.6 mm, 0.9 mm) according to IPEM 78 Publication. Results The calculated total absorbed dose in the eye lens depends on the initial incident spectra. This quantity normalized to the eye dose, is between 1.8% and 2.3% in the studied cases and increases with increasing the depth of the eye lens’ location. Comparison to experimental data is also provided. Conclusions The equivalent dose at a depth of 3 mm Hp (3) is likely to be the appropriate quantity for the best estimate of the eye lens dose. Recent studies showed equivalent dose at a depth of 0.07 mm, Hp (0.07) to be adequate in some cases to monitor the eye lens in interventional radiology, instead of equivalent dose at a depth of 3 mm, Hp (3). The aim of this study was to investigate by Monte Carlo calculations the dose deposition within the eye lens and contribute to the choice of the appropriate dose quantity. The XRayImagingSimulator was used to model the patient, the operator and the interventional diagnostic unit as well as to calculate the dose within the operators eyes by use of Monte Carlo techniques. Eye lens were placed in three different depths within the eye: 2.3 mm, 3.3 mm, 4.3 mm, representing mean depth and the limits found in a normal adult population. The primary spectra were calculated for 70 kV tube voltage, 12° tungsten target, 3 mm aluminum inherent filtration with an additional copper filtration (0.1 mm, 0.3 mm, 0.6 mm, 0.9 mm) according to IPEM 78 Publication. The calculated total absorbed dose in the eye lens depends on the initial incident spectra. This quantity normalized to the eye dose, is between 1.8% and 2.3% in the studied cases and increases with increasing the depth of the eye lens’ location. Comparison to experimental data is also provided. The equivalent dose at a depth of 3 mm Hp (3) is likely to be the appropriate quantity for the best estimate of the eye lens dose.