Dear Editor, Accessing reliable information in the 21st century can be challenging, particularly with the ease of access to data through technology. For both society and health professionals, the integrity of information is of utmost importance. Evidence-based medicine (EBM) offers a framework for evaluating the reliability of sources through rigorous scientific methods, including experimentation, falsification, and data accumulation (1). Medical knowledge has historically evolved through continuous refinement, with evidence being established via repeated experiments and analyses. Reliable information stems from multiple confirmations rather than isolated findings. EBM uses a hierarchy of evidence to categorize research by its reliability, facilitating informed clinical decision-making. It presents a structured approach to medical diagnosis, treatment, and follow-up strategies based on evidence levels (Grade Practice Recommendations, A-D) (2). The importance of EBM is emphasized in the digital era, promoting a systematic and reliable presentation of information. To combat misinformation, it is important to exercise critical thinking and skepticism toward information sources. Accessing reliable medical information is of crucial importance, especially in times of crisis such as the COVID-19 pandemic (3). Primary sources, including peer-reviewed journals, respected international guidelines, scientific reports, and reputable textbooks play a pivotal role in providing accurate and trustworthy information. For example, The National Institute for Health and Clinical Excellence (NICE) and the Cochrane Library offer evidence-based information that has undergone peer review (5,6). The pandemic has highlighted the significance of open access to scientific publications, which has facilitated global information sharing and accelerated vaccine development, ultimately reducing morbidity and mortality rates. This event has underscored the necessity of reliable information sources and the importance of continued collaboration and cooperation in the scientific community. Misinformation, particularly on social media, can pose significant challenges when it comes to verifying the accuracy of online information. To differentiate between truth and falsehood, it is crucial to employ critical evaluation methods, such as cross-referencing multiple sources and examining evidence consistency. Educational initiatives on media and health literacy from a young age, as well as platforms dedicated to verifying claims, can play a vital role in countering misinformation (6). In the digital age, family physicians face both opportunities and challenges due to the abundance of online information. It is very important to acknowledge that quick access to a wide range of data is invaluable for informed decision-making in patient care. However, the vast amount of information available also poses the risk of encountering unreliable or outdated sources. Therefore, it is crucial to utilize reputable medical literature and evidence-based resources (7). For family physicians, it is important to remain up-to-date with the latest research and guidelines through respected indexes such as Web of Science, PubMed, and Scopus. This practice not only helps in delivering high-quality patient care but also supports lifelong learning and professional development (8). Additionally, recent global health crises have emphasized the need for quick access to accurate and reliable medical information to effectively address public health emergencies (6). Therefore, discerning and accessing reliable information sources are indispensable skills for family physicians in the digital age. Keywords: evidence-based medicine, information sources, family practice, practice guideline, resource guides