Background and Objectives: Background and Aim: Validity Scale Validation can help identify coronavirus disease patients; therefore, the aim of this study was to evaluate the validation of the electronic form of the Oxford Happiness Questionnaire in patients with COVID-19. Methods: This study is instrumental psychometrics that the statistical population includes all patients in 19 cases in Tehran. The number of samples was determined based on psychometric criteria to be 100 for the predictive validity section and 251 for the convergence validity section. Samples were selected by cluster sampling. Research data were collected electronically through two questionnaires of happiness (Oxford) and happiness of positive psychological characteristics by sending the questionnaire link to the participants' mobile phones. To evaluate the validity of the scale, content validity, convergence, and factor analysis methods were used. The reliability of the scale was assessed by internal consistency methods and class reliability. Results: The results of exploratory factor analysis showed that the researcher-made questionnaire consists of three factors and has good validity and reliability. The second-order confirmatory factor analysis also confirmed the three-factor model. This questionnaire was administered along with the short form of the Oxford Happiness Scale, which had 13 items of good reliability and validity. Conclusion: The Oxford Happiness Scale in COVID-19 patients can be used to assess happiness in COVID-19 patients.