For a category of uncertain nonlinear systems with output constraint and actuator failures, the fixed-time event-triggered control method is investigated. Output constraint and actuator failures are common in practical systems, which may affect the performance of the system. Most of the existing schemes to deal with these problems only guarantee the system's asymptotic stability. It is a challenge to design event-triggered based controllers to achieve fixed-time stability of a system with the above constraints. To handle the above problems, barrier Lyapunov functions (BLFs) and extended fuzzy logic systems (EFLSs) are introduced to the backstepping procedure. Besides, to reduce redundant data transmissions, an event-triggered mechanism (ETM) is designed. On this foundation, a fixed-time event-triggered control method is proposed. Technically, by using the proposed method, the controlled system is practically fixed-time stable, and the system output abides by the corresponding constrained requirements. Meanwhile, the communication resources are saved. Finally, some simulation examples are used to demonstrate the effectiveness of the control method.