Abstract: In recent years considerable attention has been paid to research and development of structural vibration control devices with particular emphasis on mitigation of wind and seismic response of buildings. Many vibration-control measures like passive, active, semi-active and hybrid vibration control methods have been developed. Base isolation is a passive vibration control system. The isolator partially reflects and partially absorbs input seismic energy before it gets transmitted to the superstructure. Lead rubber bearing isolators are placed between the superstructure and foundation, which reduces the horizontal stiffness of the system. It thereby increases the time period of the structure and decreases the spectral acceleration of the structure. The superstructure acts like a rigid body, thus inter storey drift is reduced. This study is concerned with the effects of various vertical irregularities on the seismic response of a structure and controls this response using base isolation. The objective of the study is to carry out response spectrum analysis. The predominant lateral loads acting upon building structures are earthquake and wind induced forces. If wind load is much greaterthan earthquake load, the lateral force resisting system required to tackle wind loading may be enough to resist the smaller earthquake load. In this situation, a seismic base isolator will not bring any benefit to the building system. Furthermore, if time period of a building without isolator is greater, incorporation of isolator will not bring much difference to the building behavior with respect to seismic load. Additionally, for buildings with lowerstructural time periods, incorporation of an isolator will greatly alter the seismic behavior
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