A large part of the energy for heating and cooling is consumed due to human needs for thermal comfort in the living environment. It is important to use a suitable method to design an energy-efficient building to satisfy the thermal comfort of residents throughout the year. This paper focuses on the implementation of the sensitivity analysis in the area of energy analysis of a prefabricated timber building on box models. The sensitivity analysis plays an important role in early planning, partially also presenting the energy analysis. A combination of the building energy simulation and the sensitivity analysis technique identifies key variables by order, which can either have a strong or insignificant impact on the further design of the energy efficiency of a building. Moreover, this paper presents a sensitivity analysis method performed on the case study of six different timber building models where design parameters, such as geometry, insulation features, glazing ratio and distribution, shading control and interior set-point temperatures, are varied in environments with different climatic conditions: moderate (Ljubljana), warm (Athens), and cold (Helsinki). The sensitivity analysis for a range of variable input parameters is conducted by using the global sensitivity analysis technique, i.e. the Morris method, which is based on the elementary effect. The main objective of the article is to provide guidance for researchers, professionals and building planners about the parameters they should focus on in the early planning of an energy-efficient timber building to reduce the energy required for heating and cooling, thereby ensuring constant thermal comfort in the living environment. The results of the sensitivity analysis, which serve as guidelines, show that the overall U-factor of a window, the solar heat gain coefficient, and a set-point temperature for heating are design variables that most affect the heating energy demand for the considered one- and two-storey box models in the three locations. The dominant parameters have on average 30% more influence on heating energy demand in cold climates than parameters in moderate climates and 88% more than in warm climates. While shading control and solar heat gain coefficient are the most influential parameters for cooling energy demand, with the dominant parameters in warm climates having on average 39% more influence than parameters in moderate climates and 49% more influence than parameters in cold climates. In the total energy demand for the operation of all box models under all climatic conditions, special attention should be paid to shading control. In addition, in moderate and cold climates, the overall U-value of the window and the internal set- point temperature in winter must be considered, and in hot climates, the solar heat gain coefficient is important. In the case of the two-storey box model, designers need to be careful about the glazing-to-wall ratio which depends on the orientation of the glazing (south-north or east-west). In this case, the dominant parameters have on average 47% more influence in warm climates than in cold climates and 56% more than in temperate climates.
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