To develop digital twin (DT) of road infrastructure, one critical element is computation of pavement responses (strains, stresses, and deflections) under traffic and environmental loading. This study aims to develop high-efficient asphalt pavement modeling software based on semi-analytical finite element method (SAFEM) for DT application. The algorithms address important aspects in vehicle-tire-pavement interaction modeling, such as dynamic vehicular loading, three-dimensional (3-D) non-uniform tire contact stress, viscoelastic behavior of asphalt material, and interface bonding condition. The simulation accuracy is verified by comparison with full-scale test and field measurements, and the relative differences are around 5 % to 20 %. Techniques including optimized discrete Fourier transform, parallel computing, graphics processing unit (GPU) acceleration, and sparse matrices are implemented for computation efficiency. As compared to the traditional 3-D FEM, SAFEM shows significant savings in computation time and storage usage. The high efficiency and accuracy make the software full of potential to be applied for DT of roadway infrastructure.