Beetroot Juice Consumption Research Articles

The Effects of Acute Beetroot Juice Intake on Glycemic and Blood Pressure Responses When Controlling for Medication in Individuals with Type 2 Diabetes: A Pilot Study.

Physical inactivity and poor dietary choices contribute to the rise in cardiometabolic diseases in the United States. It remains critical to identify strategies that may mitigate the negative impact of these behaviors. Several studies have shown that the consumption of dietary inorganic nitrate may improve vascular health and glucose regulation in animal models and some human studies. However, the improvements in glucose regulation have yet to be corroborated in humans with type 2 diabetes (T2D). Therefore, the purpose of this study was to assess the acute effects of beetroot juice (BRJ) on glycemic and hemodynamic responses in individuals with T2D while controlling for medication. Seven participants with a clinical diagnosis of T2D were recruited into this study and were temporarily removed from blood pressure- and glucose-lowering medications. Hemodynamic measurements (pulsewave velocity) and an oral glucose tolerance test (glycemic response) were measured following consumption of either BRJ or a denitrolized placebo. Saliva and blood samples were collected at baseline and two and four hours post supplementation to measure changes in nitrate and nitrite concentrations. We detected significant improvements in total plasma glucose exposure (p = 0.022) and the SVR change score (p = 0.009) in the BRJ condition. This study demonstrated that BRJ consumption can improve oral glucose tolerance in individuals with T2D while controlling for medication; however, future larger-cohort randomized controlled trials are needed to confirm if BRJ is a viable treatment for glucose control in individuals with T2D.

The acute effects of dietary nitrate supplementation on postmenopausal endothelial resistance to ischemia reperfusion injury: a randomized, placebo-controlled, double blind, crossover clinical trial.

Postmenopausal cardiovascular health is a critical determinant of longevity. Consumption of beetroot juice (BR) and other nitrate-rich foods is a safe, effective non-pharmaceutical intervention to increase systemic bioavailability of the vasoprotective molecule, nitric oxide, through the exogenous nitrate (NO3 -)-nitrite (NO2 -)-nitric oxide (NO) pathway. We hypothesized that a single dose of nitrate-rich beetroot juice (BRnitrate 600 mg NO3 -/140 mL, BRplacebo ∼ 0 mg/140 mL) would improve resting endothelial function and resistance to ischemia-reperfusion (IR) injury to a greater extent in early-postmenopausal (1-6 years following their final menstrual period (FMP), n=12) compared to late-postmenopausal (6+years after FMP, n=12) women. Analyses with general linear models revealed a significant (p<0.05) time*treatment interaction effect for brachial artery adjusted flow-mediated dilation (FMD). Pairwise comparisons revealed that adjusted FMD was significantly lower following IR-injury in comparison to all other time points with BRplacebo (early FMD 2.51±1.18%, late FMD 1.30±1.10, p<0.001) and was lower than post-IR with BRnitrate (early FMD 3.84±1.21%, late FMD 3.21±1.13%, p=0.014). A single dose of BRnitrate significantly increased resting macrovascular function in the late postmenopausal group only (p=0.005). Considering the postmenopausal stage-dependent variations in endothelial responsiveness to dietary nitrate, we predict differing mechanisms underpin macrovascular protection against IR injury.

Effectivity of Beetroot in Increasing Pregnant Women Hemoglobin

The background is that anemia is a major problem in pregnancy women. According to Riskesdas 2019 there are 20.1 % of anemia in West Java. In Cimenyan Public Health Center area there are 37% pregnant women with anemia at 2022. The government has done efforts to reduce this condition by giving the iron tablets to pregnant women. Food supplementation that are rich of iron nutrition such as beetroot consumption can increase the hemoglobin. From the prelimary studies founded that 6 from 10 pregnant women never exprerience consuming beetroot and doesnt know the benefits of consuming beetroot. The aim of the study is to know the effectivity of consuming beetroot in increasing hemoglobin of pregnant women with anemia. The methode is quasy experiment with one group pretest and post-test design, with purposive sampling technique, with 34 subjects. This research use the standard procedure of processing and consuming beetroot. Respondent’s hemoglobin are measure with hemoglobinometer before and after beetroot comsumption. The statistic use bivariate analysis with Wilcoxon test. The result is that the hemoglobin median value from 34 subjects before consuming beetroot juice is 9.75 gr/dl, and after consuming beetroot juice is 10.7 gr/dl. From the statistic test is Sig value (0,000) that means the beetroot juice consumption effectivity increases hemoglobin level in pregnant women with anemia. The conclusion is that the consuming beetroot is effective in increasing pregnant women hemoglobin with anemia.

Effects of Acute Beetroot Juice and Sodium Nitrate on Selected Blood Metabolites and Response to Transient Ischemia: A Crossover Randomized Clinical Trial

BackgroundModification of the nitrate (NO3)–nitrite (NO2)–nitric oxide (NO) pathway can be induced by oral intake of inorganic NO3 (NIT) or NO3-rich products, such as beetroot juice (BRJ). ObjectivesThe primary aim of this study was to evaluate the plasma changes in betaine, choline, trimethylamine (TMA), trimethylamine N-oxide (TMAO), and NO3/NO2 (NOx) concentrations over 4 h after single oral ingestion of NIT or BRJ. The flow-mediated skin fluorescence (FMSF) method was applied to measure the changes in nicotinamide adenine dinucleotide reduced form (NADH) in response to transient ischemia and reperfusion. We hypothesized that various sources of NO3 may differently affect endothelial and mitochondrial functions in healthy human subjects. MethodsIn a randomized crossover trial, 8 healthy young adults ingested 800 mg NO3 from either NIT or BRJ on 2 separate days with ≥3 d apart. Venous blood samples were collected every hour, and FMSF determination was applied bihourly. ResultsPlasma betaine and choline concentrations peaked at 1 h after BRJ ingestion, and remained significantly higher than baseline values at all time points (P < 0.001 and P < 0.001, compared to preingestion values). Over time, BRJ was more effective in increasing NOx compared with NIT (fixed-trial effect P < 0.001). Baseline fluorescence decreased after both NIT and BRJ consumption (fixed-time effect P = 0.005). Transient ischemia and reperfusion response increased because of NO3 consumption (fixed-time effect P = 0.003), with no differences between trials (P = 0.451; P = 0.912; P = 0.819 at 0, 2, and 4 h, respectively). ConclusionsAcute ingestion of BRJ elevated plasma betaine and choline, but not TMA and TMAO. Moreover, plasma NOx levels were higher in the BRJ trial than in the NIT trial. Various sources of NO3 positively affected endothelial and mitochondrial functions.This trial was registered at clinicaltrials.gov as NCT05004935.

Pengaruh Pemberian Jus Umbi Bit terhadap Kadar Hemoglobin Ibu Hamil Trimester III

WHO data (2020), it estimated that worldwide around 32 million pregnant women have anemia. In Indonesia, the incidence of anemia in pregnant women increased in 2018 by 48.8% when compared to 2013, which was 37.1%. Garut Regency in 2019 the prevalence of pregnant women with anemia was 6669 people. Karangpawitan Health Center in 2021, out of 834 pregnant women, 31.5% experienced anemia in the first trimester and as many as 168 pregnant women in third trimester (20.1%). Non-pharmacologically the treatment and prevention of anemia is by consuming green vegetables, nuts, chicken liver, beet tubers, red guava fruit and others. The content of beet tubers in the list of food ingredients includes 108 mg of folic acid, 27.0 mg of calcium, 43.0 mg of phosphorus, 43 mg of vitamin C, 23 mg of magnesium, 9.6 mg of carbohydrates, 1.0 mg of iron (Ministry of Health RI, 2016). Folic acid is very good to help the formation of the baby's brain and overcome the problem of anemia. The purpose of the study was to determine the effect of beetroot juice on hemoglobin levels of pregnant women in the third trimester at Karangpawitan Public Health Center, Garut Regency. The methodology of this research uses Pre test - Post test with control group design. The population in the study were all pregnant women in the third trimester as many as 129 people The samples in this study were TM III pregnant women who experienced mild anemia using purposive sampling as many as 30 people who were divided into 2 groups, namely 15 people in the experimental group and 15 people in the control group. The instruments used are observation sheets and technical instructions for beetroot juice. Data analysis used Paired T-test and Independent Samples Test. The results of the study the average hemoglobin level in the experimental group before being given beet juice was 9.160 and after beet juice was 10.807, while in the control group before the intervention was 8.933 and after the intervention was 9.813. The bivariate results showed a p-value of 0.000 &lt;0.05. The conclusion is that there is an effect of giving beetroot juice + Fe tablets on hemoglobin levels of pregnant women in the third trimester at Karangpawitan Health Center, Garut Regency In 2023. With this study, consumption of beet root juice can be an alternative in increasing hemoglobin levels in pregnant women.

Influence of Consumption of Nitrate-rich Beetroot Juice on Lactate Production in Saliva and Oral Biofilm - A Clinical Trial.

Diets rich in nitrates have the potential to prevent oral diseases such as caries or periodontitis. The reduced forms nitrite and nitric oxide have an antibacterial effect against cariogenic bacteria. The effect on bacterial acid production in saliva and oral biofilm is yet unknown. This study investigated the influence of consuming naturally nitrate-rich beetroot juice on bacterial lactate production in saliva and on the pH value of saliva and oral biofilm. In addition to their usual diet, a study group of eight subjects consumed 50 ml of beetroot juice daily for a fortnight. After a two-week break, they rinsed with 0.2% chlorhexidine (CHX) for 14 days as a positive control. Bacterial lactate production was induced by rinsing with 50 ml apple juice and measured at different time points during the study. After two weeks of daily beetroot-juice consumption, an accumulation of nitrate and nitrite was measured in the saliva. No influence on the bacterial lactate production in saliva or the saliva and plaque pH was found. Commercially available beetroot juice showed no modulating effects on intraoral bacterial acid production, suggesting no caries-preventive properties under the tested conditions.

Effect of Beetroot Juice Supplementation on Muscle Soreness and Performance Recovery after Exercise-Induced Muscle Damage in Female Volleyball Players.

Beetroot juice (BRJ) contains various bioactive compounds suggested to be effective in improving athlete recovery. However, the number of studies evaluating the effects of BRJ on recovery and muscle soreness (MS) indicators in female athletes is limited. Therefore, the present study aimed to determine the effects of BRJ consumption on the performance recovery indicators and MS after exercise-induced muscle damage (EIMD) in female volleyball players. Twelve young female volleyball players were evaluated in this study. We utilized a randomized, cross-over, and double-blind design during two phases with a 30-day interval (wash-out). During each phase, EIMD was performed first, followed by BRJ or placebo (PLA) supplementation for two days (eight servings of 50 mL). Recovery monitoring of performance indicators and MS was performed after EIMD. The results of wall-sit, V sit and reach (VSFT), vertical jump height (VJH), pressure pain threshold (PPT), and thigh swelling (Sw-T) tests were recorded 48 h after EIMD. Also, the Perceived Muscle Soreness was recorded using the visual analog scale (VAS) 12 (MS-12 h), 24 (MS-24 h), and 48 (MS-48 h) hours after EIMD. The data were analyzed using two-way repeated measures of ANOVA at p < 0.05. Compared to PLA, BRJ supplementation improves wall-sit performance after EIMD (p < 0.05), while reducing Sw-T and perceived muscle soreness (p < 0.05). However, no significant difference was observed between PLA and BRJ in VJH and VSFT performance after EIMD (p > 0.05). Our findings indicate that the consumption of BRJ in female volleyball players can be useful for improving some recovery indicators, such as muscle endurance, perceived muscle soreness, and tissue edema, after EIMD.

Acute beetroot juice consumption does not alter cerebral autoregulation or cardiovagal baroreflex sensitivity during lower-body negative pressure in healthy adults.

Beetroot juice (BRJ) improves peripheral endothelial function and vascular compliance, likely due to increased nitric oxide bioavailability. It is unknown if BRJ alters cerebrovascular function and cardiovagal baroreflex control in healthy individuals. We tested the hypotheses that BRJ consumption improves cerebral autoregulation (CA) and cardiovagal baroreflex sensitivity (cBRS) during lower-body negative pressure (LBNP). Thirteen healthy adults (age: 26 ± 4 years; 5 women) performed oscillatory (O-LBNP) and static LBNP (S-LBNP) before (PRE) and 3 h after consuming 500 mL of BRJ (POST). Participants inhaled 3% CO2 (21% O2, 76% N2) during a 5 min baseline and throughout LBNP to attenuate reductions in end-tidal CO2 tension (PETCO2). O-LBNP was conducted at ∼0.02 Hz for six cycles (-70 mmHg), followed by a 3-min recovery before S-LBNP (-40 mmHg) for 7 min. Beat-to-beat middle cerebral artery blood velocity (MCAv) (transcranial Doppler) and blood pressure were continuously recorded. CA was assessed using transfer function analysis to calculate coherence, gain, and phase in the very-low-frequency (VLF; 0.020-0.070 Hz) and low-frequency bands (LF; 0.07-0.20 Hz). cBRS was calculated using the sequence method. Comparisons between POST vs. PRE are reported as mean ± SD. During O-LBNP, coherence VLF was greater at POST (0.55 ± 0.06 vs. 0.46 ± 0.08; P < 0.01), but phase VLF (P = 0.17) and gain VLF (P = 0.69) were not different. Coherence LF and phase LF were not different, but gain LF was lower at POST (1.03 ± 0.20 vs. 1.12 ± 0.30 cm/s/mmHg; P = 0.05). During S-LBNP, CA was not different in the VLF or LF bands (all P > 0.10). Up-cBRS and Down-cBRS were not different during both LBNP protocols. These preliminary data indicate that CA and cBRS during LBNP in healthy, young adults is largely unaffected by an acute bolus of BRJ.

Effect of two-week red beetroot juice consumption on modulation of gut microbiota in healthy human volunteers – A pilot study

With very little research exploring intestinal effects of red beetroot consumption, the present pilot study investigated gut microbial changes following red beetroot consumption, via a 14-day intervention trial in healthy adults. Compared to baseline, the study demonstrates transient changes in abundance of some taxa e.g., Romboutsia and Christensenella, after different days of intervention (p < 0.05). Enrichment of Akkermansia muciniphila and decrease of Bacteroides fragilis (p < 0.05) were observed after 3 days of juice consumption, followed by restoration in abundance after 14 days. With native betacyanins and catabolites detected in stool after juice consumption, betacyanins were found to correlate positively with Bifidobacterium and Coprococcus, and inversely with Ruminococcus (p < 0.1), potentiating a significant rise in (iso)butyric acid content (172.7 ± 30.9 µmol/g stool). Study findings indicate the potential of red beetroot to influence gut microbial populations and catabolites associated with these changes, emphasizing the potential benefit of red beetroot on intestinal as well as systemic health.

Efficacy and Variability in Plasma Nitrite Levels during Long-Term Supplementation with Nitrate Containing Beetroot Juice

Long-term consumption of beetroot juice on efficacy of converting dietary nitrate to plasma nitrate and nitrite was investigated. Adults were randomized to consume either beetroot juice with 380 mg of nitrate (BR) or a beetroot juice placebo (PL) for 12-weeks. Plasma nitrate and nitrite were measured before and 90-minutes after consuming their intervention beverage. Percent change in nitrite across the 90 min was greater in BR (273.2 ± 39.9%) vs. PL (4.9 ± 36.9%). Long-term consumption of nitrate containing beetroot juice increased fasting nitrate and nitrite plasma levels compared to baseline.

The effects of dietary nitrate supplementation in post‐menopausal women: Does timing matter?

There is a need for low risk, non‐estrogen therapies for cardiovascular disease prevention in post‐menopausal women, a population expected to reach 1.2 billion worldwide by 2030. Consumption of beetroot juice and other nitrate‐rich products (green leafy vegetables, supplements) is a promising non‐pharmaceutical strategy for increasing circulating nitric oxide levels and improving vascular function in post‐menopausal women. Whether time since menopause (reproductive age) influences the vasoprotective effects (arterial stiffness and endothelial function) of dietary nitrate supplementation has not been established.PURPOSETo determine the vascular protective mechanisms and efficacy of a nitric oxide boosting supplement (beetroot juice) in women at two post‐ menopausal stages (early‐ vs late‐post menopause).METHODSEarly‐ (1‐6 years following their final menstrual cycle, n=5) and late‐ (n=10) postmenopausal women consumed nitrate‐rich (300 mg/70 mL) and nitrate‐depleted beet root juice acutely and for 7 days. Percent brachial artery flow‐mediated dilation (FMD) was measured at baseline, acutely (90 minutes post‐BRJ consumption), and 15‐minutes and 30‐minutes after 20‐minute upper arm ischemia‐reperfusion (IR) injury for each drink. Brachial‐ankle pulse wave velocity (baPWV) was measured pre‐ and post‐ 7‐day supplementation.RESULTSDue to the nature of this double‐blind trial, data presented are from the baseline (pre‐juice consumption) visit only. Significant (p&lt;0.05) group differences were observed for baseline PWV (early = 1158+115 cm/s; late = 1469+296 cm/s) and FMD at the 30‐minute post‐IR injury timepoint (early = 8.4+4.6%; late = 5.8+2.7%). No group differences were observed in FMD responses at rest (p=0.2) or 15 minutes post‐IR injury (p=0.4).CONCLUSIONThese preliminary results suggest that time since menopause negatively influences arterial stiffness and may prolong recovery from endothelial IR injury in women.

Effect of Vitamin C and Protein Supplementation on Plasma Nitrate and Nitrite Response following Consumption of Beetroot Juice.

Beetroot juice is a food high in nitrate and is associated with cardiometabolic health benefits and enhanced exercise performance through the production of nitric oxide in the nitrate–nitrite–nitric oxide pathway. Since various food components influence this pathway, the aim of this trial was to study the effect of beetroot juice alone and in conjunction with vitamin C or protein on the acute response to plasma nitrate and nitrite levels in healthy middle- to older-aged adults. In this cross-over trial, each participant received, in a randomized order, a single dose of Beet It Sport® alone; Beet It Sport®, plus a 200 mg vitamin C supplement; and Beet It Sport® plus 15 g of whey protein. Plasma levels of nitrate and nitrite were determined prior to and at 1 and 3 h after intervention. Log plasma nitrate and nitrite was calculated to obtain data that were normally distributed, and these data were analyzed using two-way within-factors ANOVA, with time and treatment as the independent factors. There were no statistically significant differences for log plasma nitrate (p = 0.308) or log plasma nitrite (p = 0.391) values across treatments. Log plasma nitrate increased significantly from pre-consumption levels after 1 h (p < 0.001) and 3 h (p < 0.001), but plasma nitrate was lower at 3 h than 1 h (p < 0.001). Log plasma nitrite increased from pre to 1 h (p < 0.001) and 3 h (p < 0.001) with log values at 3 h higher than at 1 h (p = 0.003). In this cohort, we observed no differences in log plasma nitrate and nitrite at 1 h and 3 h after co-ingesting beetroot juice with vitamin C or a whey protein supplement compared to beetroot juice alone. Further research needs to be undertaken to expand the blood-sampling time-frame and to examine factors that may influence the kinetics of the plasma nitrate to nitrite efficacy, such as differences in fluid volume and osmolarity between treatments employed.

Dietary Nitrate Supplementation Does Not Alter Exercise Efficiency at High Altitude - Further Results From the Xtreme Alps Study.

IntroductionNitrate supplementation in the form of beetroot juice (BRJ) ingestion has been shown to improve exercise tolerance during acute hypoxia, but its effect on exercise physiology remains unstudied during sustained terrestrial high altitude exposure. We hypothesized that performing exercise at high altitude would lower circulating nitrate and nitrite levels and that BRJ ingestion would reverse this phenomenon while concomitantly improving key determinants of aerobic exercise performance.MethodsTwenty seven healthy volunteers (21 male) underwent a series of exercise tests at sea level (SL, London, 75 m) and again after 5–8 days at high altitude (HA, Capanna Regina Margherita or “Margherita Hut,” 4,559 m). Using a double-blind protocol, participants were randomized to consume a beetroot/fruit juice beverage (three doses per day) with high levels of nitrate (∼0.18 mmol/kg/day) or a nitrate-depleted placebo (∼11.5 μmoles/kg/day) control drink, from 3 days prior to the exercise trials until completion. Submaximal constant work rate cycle tests were performed to determine exercise efficiency and a maximal incremental ramp exercise test was undertaken to measure aerobic capacity, using breath-by-breath pulmonary gas exchange measurements throughout. Concentrations of nitrate, nitrite and nitrosation products were quantified in plasma samples collected at 5 timepoints during the constant work rate tests. Linear mixed modeling was used to analyze data.ResultsAt both SL and HA, plasma nitrate concentrations were elevated in the nitrate supplementation group compared to placebo (P < 0.001) but did not change throughout increasing exercise work rate. Delta exercise efficiency was not altered by altitude exposure (P = 0.072) or nitrate supplementation (P = 0.836). V̇O2peak decreased by 24% at high altitude (P < 0.001) and was lower in the nitrate-supplemented group at both sea level and high altitude compared to placebo (P = 0.041). Dietary nitrate supplementation did not alter other peak exercise variables or oxygen consumption at anaerobic threshold. Circulating nitrite and S-nitrosothiol levels unexpectedly rose in a few individuals right after cessation of exercise at high altitude.ConclusionWhilst regularly consumed during an 8 days expedition to terrestrial high altitude, nitrate supplementation did not alter exercise efficiency and other exercise physiological variables, except decreasing V̇O2peak. These results and those of others question the practical utility of BRJ consumption during prolonged altitude exposure.

Effectiveness of Beet Root Juice on Reduction of Blood Pressure among People with Hypertension at Sothupakkam, Kanchipuram District

Aim: Effectiveness of beet root juice on reduction of blood pressure among people with hypertension at Sothupakkam, Kanchipuram district Objectives: (i) to assess the level of blood pressure among people with hypertension residing at Sothupakkam. (ii) to evaluate the effectiveness of beetroot juice on reduction of blood pressure among people with hypertension (iii) to find out the association between effectiveness of beetroot juice on reduction of blood pressure with the selected demographic variables. Methodology: Researcher adopted the quantitative research approach, one group pre test and post test design, study samples with the age group 25-65 years old for 60 samples at Sothupakkam Kanchipuram district using purposive sampling technique Results: The findings of the study was pre and post systolic mean difference 30.66 with the standard deviation 10.39 and applying paired ‘t’ test value 22.8 and pre and post diastolic mean difference 17.33 with standard deviation 10.22 and applying the paired ‘t’ test value 13.1 since the calculated value was greater than the table value at 0.05 level of significance. Hence it was significant improvement in reduction of blood pressure among people with hypertension. It has shown that the consumption of beet root juice was effective Conclusion: The present study was conducted in sothupakkam village with the sample size 60 people with hypertension and they had been administered with the beet root juice on reduction of blood pressure which showed the remarkable changes in the health status of the susceptible of people with hypertension and they had give the feedback regarding the effectiveness of the natural home remedy. Keywords: Beet root juice, hypertension, high blood pressure.

Acute Beetroot Juice Ingestion Does Not Alter Renal Hemodynamics during Normoxia and Mild Hypercapnia in Healthy Young Adults

Arterial hypercapnia reduces renal perfusion. Beetroot juice (BRJ) increases nitric oxide bioavailability and may improve renal blood flow. We tested the hypothesis that acute consumption of BRJ attenuates both decreases in blood velocity and increases in vascular resistance in the renal and segmental arteries during acute hypercapnia. In fourteen healthy young adults, blood velocity and vascular resistance were measured with Doppler ultrasound in the renal and segmental arteries during five minutes of breathing a carbon dioxide gas mixture (CO2) before and three hours after consuming 500 mL of BRJ. There was no difference between pre- and post-BRJ consumption in the increase in the partial pressure of end-tidal CO2 during CO2 breathing (pre: +4 ± 1 mmHg; post: +4 ± 2 mmHg, p = 0.4281). Segmental artery blood velocity decreased during CO2 breathing in both pre- (by −1.8 ± 1.9 cm/s, p = 0.0193) and post-BRJ (by −2.1 ± 1.9 cm/s, p = 0.0079), but there were no differences between pre- and post-consumption (p = 0.7633). Segmental artery vascular resistance increased from room air baseline during CO2 at pre-BRJ consumption (by 0.4 ± 0.4 mmHg/cm/s, p = 0.0153) but not post-BRJ (p = 0.1336), with no differences between pre- and post-consumption (p = 0.7407). These findings indicate that BRJ consumption does not attenuate reductions in renal perfusion during acute mild hypercapnia in healthy young adults.

The effectiveness of giving beetroot juice on increasing Haemoglobin (Hb) levels of adolescent women in Islamic Boarding School

Background: About 50% of cases of anemia are due to iron deficiency, Southeast Asian State was in the 2 nd highest position for anemia compared to other countries. The incidence of anemia is at greater risk in women due to natural conditions such as menstruation, pregnancy and childbirth as well as the food consumed. The prevalence of anemia in Indonesia is 21,7% with a proportion of 20,6% in urban areas and 22.8% in rural areas. Purpose: The purpose of this study was to determine the effectiveness of giving beetroot juice to increase hemoglobin levels in the blood in adolescents women in Islamic boarding school. Method: This research was conducted using a pre-experimental method with one group pretest post-test design. The intake of 60 g of beetroot is consumed in the form of 200 ml/day of beetroot juice for 7 days. Result: There is a significant difference hemoglobin levels before and after giving beetroot juice in adolescent women at Islamic boarding school (p=0.001). Conclution: Consumption of beetroot juice has an effect on increasing hemoglobin levels in adolescent women.

Beetroot Juice - Legal Doping for Athletes?

Nitric oxide (NO) is a physiologically important signaling molecule that promotes the expansion of blood vessels and thus facilitates the transport of oxygen (O2) and energy substrates to the muscles. Research shows that nitric oxide (NO) also improves the effectiveness of mitochondrial respiration, which is manifested by reduced oxygen consumption during exercise. Until recently, it was thought that nitric oxide (NO) could only be formed as a result of the endogenous pathway of oxidative transformations L-arginine. Recent research results indicate, however, that an alternative to the endogenous pathway of nitric oxide (NO) formation may be the exogenous supply of inorganic nitrates (NO3-) with food. The aim of the study was to review the current literature on the properties of beetroot juice as an important source of nitrates (NO3-) and its effectiveness in improving the exercise capacity of physically active people. A systematic review of the research, published from 2005 to January 31, 2021, was made on the basis of searching bibliographic databases such as: PubMed, Elsevier and Web of Science. The following keywords were used: “beetroot”, “beetroot juice”, “nitrates”, “nitrites”, “nitric oxide”, “supplementation”, “ergogenic substances”, “sports nutrition”. Although there are conflicting data, it appears that beetroot juice supply may be a cheap, natural, and promising nutritional strategy for improving sports performance in both endurance and intermittent high intensity (start-stop) exercise. More detailed studies are analyzing the effect of dietary nitrate (NO3-) supply in anaerobic exercise - especially in high-volume resistance training - are needed. It is also emphasized that further research is needed to elucidate the effects of specific factors on the variability of ergogenic effects after beetroot juice consumption, which may be of the greatest importance in terms of the effectiveness of this nutritional intervention.

Effects of Beetroot Juice Supplementation on Inflammation and Antioxidant Levels in Obese Subjects

Beetroot is a vegetable high in organic nitrate. Dietary nitrate derived from beetroot is absorbed from the gut, taken up into the salivary glands and concentrated in the saliva. Nitrate is converted enzymatically with nitrite as an intermediary, especially under hypoxic and/or acidotic conditions to nitric oxide. Obese individuals are known to exhibit increased levels of pro-inflammatory markers and reduced antioxidants. In this placebo-controlled, randomised, double-blinded study, we determined whether beetroot juice consumption is associated with improvement in inflammation and oxidative stress.

Effect of high-nitrate beetroot juice consumption on thyroid gland hormones and iodine levels in adults

Dietary nitrate supplementation has been widely investigated by the scientific community due to its beneficial effects on the cardiovascular system. However, there is evidence suggesting a possible effect of nitrate in scavenger iodine from the thyroid gland, which may affect thyroid hormone synthesis. Therefore, this study evaluated the effect of seven days of a nitrate-rich beetroot juice supplementation on thyroid hormones and iodine concentrations in healthy adults. Thirteen healthy adults were enrolled in a randomized, double-blind, crossover and placebo-controlled study. Participants ingested 140 mL of nitrate-rich beetroot juice (8.12 ± 3.61 mmol/day) or placebo (nitrate-depleted BJ) during one week. Before and after the supplementation period, blood and urine were drawn for analysis of thyroid hormones, iodine, nitrate and nitrite. No significant changes were observed in plasma triiodothyronine, thyroxine, nitrate and nitrite, and urinary iodine concentrations. In conclusion, these results suggest that one-week supplementation with a nitrate-rich beetroot juice intake does not affect thyroid function.

Beetroot supplementation in women enjoying exercise together (BEE SWEET): Rationale, design and methods

BackgroundPostmenopausal women exhibit higher rates of disability and cardiovascular disease (CVD) with aging compared to men. Whereas habitual exercise training is a known strategy to enhance physiologic function in men and premenopausal women, exercise-related adaptations are often modest in postmenopausal women. We propose dietary nitrate (beetroot juice) administered prior to exercise training may be a feasible approach to improve mobility and cardio-metabolic health outcomes in postmenopausal women. MethodsOur randomized, placebo-controlled study aims to determine preliminary effects sizes for changes in functional mobility and endothelium-dependent vasodilation across three study arms: exercise only (EX), exercise + placebo (EX + PL), and exercise + beetroot (EX + BR). Thirty-six postmenopausal women are recruited in small cohorts wherein group exercise is implemented to facilitate social support and adherence to an 8-week training progression. Participants are randomized to one of three study arms (n = 12 per group) following baseline assessments. Post-intervention assessments are used to determine pre-post changes in outcome measures including distance covered during a 6 min walk test, walking economy, muscle speed and power, and endothelial-dependent vasodilation as determined by flow-mediated dilation. Measures of feasibility include recruitment, retention, adherence to exercise prescription, perceived exercise session difficulty, and adverse event rates. DiscussionEvidence-based, translational strategies are needed to optimize exercise training-related adaptations in postmenopausal women. Findings will inform larger randomized clinical trials to determine if pre-exercise consumption of beetroot juice is an efficacious strategy to promote mobility and attenuate CVD disease risk.