The fluctuation of housing prices and its influencing factors are important research topics in economics. Under the current background of rapid globalization and urbanization, understanding the driving factors of housing prices is not only an important contribution to academic research but also has important guiding significance for policymakers and individual home buyers. This paper explores the key factors affecting housing prices, focusing on the impact of variables such as living space, land space, housing landscape, housing conditions, housing quality, and housing construction year on housing prices. This study uses multiple regression analysis to analyze the US housing price data set. The results show that living space, housing landscape, housing quality, and housing construction year have statistically significant effects on housing prices at a significance level of 1%. This study provides an effective reference to real estate developers, policymakers, and individual home buyers, which can help them understand market demand more deeply, make decisions that are more in line with market trends, and promote the dynamic and functional development of the real estate market.