With the development of the hospital information construction, there are the continued implementations of virtualization technology in a variety of business applications, which can integrate and deploy these resources, and improve equipment utilization. In this paper, we analyze the problems existed in traditional hospital data center architecture, proposes the construction of new hospital data center using virtualization technology from the aspects of virtualization framework, server resources integration, network configuration optimization, etc. Server virtualization integration could save resources, improve server utilization ratio, simplify the hardware maintenance and upgrades, reduce operating costs and improve maintenance efficiency. We have introduced the experiences of Virtual Technology using in the hospital data center storage, the core server, integration system, network application and remote access applications, server and database platform as well as the application effects, which make a useful exploration for the building and the development of digital hospital.