Poor performance of construction projects is a re-occurring problem in Nigeria. Production flow waste (ranging from waiting time, material handling and over- production, among others) may be partly responsible for this problem. Meanwhile, very little is known about the role of the Last Planner System (LPS) in minimising production flow waste in Nigeria. The current study examines the manifestation of production flow wastes on Nigerian construction sites, identifies current construction practices that bear resemblance to the LPS, and finally, examines the prospects of the LPS concepts in minimising production flow waste in the corresponding construction projects. A mixed research design that uses a quantitative cross-sectional survey and qualitative-exploratory approach was used in collecting data from construction professionals based in Nigeria. Fifty-one survey responses were received and 10 interviews were conducted. The study reveals various incidences and contributory factors to production flow waste, with the long approval process being the most prevalent. It also identifies current practices that are similar to the LPS practices. The prospect of the LPS in production flow waste management for improved productivity is also explored. The study concludes that the LPS concept has the potential for minimising production flow waste in the construction process and improving productivity in the Nigeria construction industry.