Purpose: An individual’s confidence in the weight bearing role of the knee may be fundamental in guiding their decisions about physical activity (PA) participation. In people with knee osteoarthritis (OA), low knee confidence has been associated with fear of movement, increased pain, and decreased strength. Little is known about knee confidence and the long-term influence it may have on the behaviours of young adults with a history of knee joint injury that are at high risk of post-traumatic osteoarthritis (PTOA). In addition, the association between knee confidence and other modifiable risk factors for OA such as body composition and PA participation have not been examined in this population. The aim of this investigation was to examine knee confidence in youth and young adults who have sustained a sport-related intra-articular knee injury in their youth compared to age, sex, and sport-matched uninjured controls, adjusting for body composition and PA participation. Methods: This historical cohort study included 200 youth and young adults (15–26 years; 55% female), 100 who sustained a sport-related intra-articular knee injury 3–10 years previously [median injury age (range); 16 (9–18) years] and 100 uninjured controls matched on age, sex and sport history. Knee confidence was based on a question from the Quality of Life subscale within the Knee Osteoarthritis and Outcome Score questionnaire (KOOS): “How much are you troubled by lack of confidence in your knee?” It was measured on a 5-point likert scale (not at all, mildly, moderately, severely, or extremely) then dichotomized into ‘not at all’ or ‘bothered to some degree’ for the main analysis. Body composition was assessed by fat mass index (total fat relative to height2; FMI; kg/m2) and measured using dual-energy x-ray absorptiometry. PA participation was obtained via the modified Godin-Shepard Leisure Time Questionnaire (total minutes/week). Study groups were compared using descriptive statistics (mean within-pair difference; 95% confidence interval [95%CI]). In the final model, multivariable conditional logistic regression (odds ratio; 95% CI) was used to examine the association between injury group and knee confidence adjusting for FMI (kg/m2) and PA participation (min). Results: Among the injured participants, 49% (95%CI; 39, 59) were bothered to some degree by lack of knee confidence (37%=mildly, 7%=moderately, 4%=severely, and 1%=extremely), compared to 12% (95%CI; 5.5, 18.5) of controls (11%=mildly, 1% moderately.) Injured participants had higher FMI compared to controls [mean within pair difference=1.05 kg/m2 (95% CI; 0.53, 1.57)], however the duration of total PA/week did not differ between study groups [mean within pair difference = −6.4 min (95% CI; −28.9, 16.2)]. The univariate analysis revealed injured participants were 5.0 times more likely to be bothered by knee confidence than controls [OR= 5.0 (95%CI=2.4, 10.2)]. In the final multivariable model, the odds of low knee confidence in the injured participants was 7.5-fold that in the uninjured controls [OR=7.5 (95%CI=2.7, 21.1)], where as no association was found between knee confidence and FMI (OR=0.98 (95%CI=0.70, 1.36)] or total PA week [OR=1.0 (95%CI=1.0, 1.0)]. Conclusions: Knee confidence may be important when evaluating PTOA risk. A greater appreciation of psychological factors, including knee confidence, will inform the development of secondary prevention strategies for PTOA. Injured participants had a higher FMI than uninjured controls suggesting this could be another modifiable risk factor for further consideration. It is recommended that additional research evaluating the association of knee confidence and objectively measured PA and other clinical outcomes will inform a more comprehensive understanding of risk factors for PTOA.
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