Condensation Particle Counter Research Articles

Measurements of Total Aerosol Concentration in the Stratosphere: A New Balloon‐Borne Instrument and a Report on the Existing Measurement Record

AbstractThe Stratospheric Total Aerosol Counter (STAC) is a lightweight balloon‐borne instrument that utilizes condensational growth techniques to measure the total aerosol concentration. STAC is a miniaturized version of the legacy Wyoming condensation particle counter that operated from 1974 through 2020 in the middle latitudes and polar regions, with a few measurements in the tropics. Here we provide a description of the STAC instrument and the total aerosol measurement record, demonstrating that typical total aerosol profiles exhibit a peak in number mixing ratio, with values between 800 and 2,000 particles per mg of air (mg−1), just below the lapse rate tropopause (LRT). In the tropics and middle latitudes, mixing ratios decrease above the LRT likely due to coagulation and scavenging that results in a transfer of mass to the fewer but larger aerosol particles of the Junge layer. Exceptions to this occur in the spring time in the middle latitudes where a new particle layer between 20 and 25 km is frequently observed. In the poles, total aerosol profiles exhibit two distinct features: new particle formation in austral spring, and an increasing mixing ratio above 17 km likely due to the presence of meteoric smoke that has been concentrated within the polar vortex. High observed stratospheric particle mixing ratios, in excess of 2,000 mg−1, are observed in the polar new particle layer and at the top of polar profiles.

The investigation of traceable preparation technique of submicron particle number concentration standards in liquids

The concentration of particles at the nano- and submicron-meter scale in liquid is crucial in multiple fields including the biomedical and semiconductor industry. However, there is still a lack of metrological standards or Certified Reference Materials (CRMs) for liquid-borne particle number concentration (PNC) which could be traceable to the International System of Units (SI). To address this issue, a quantitative and value-traceable preparation technique for liquid-borne particle number concentration CRMs (PNC-CRMs) in a submicron-meter scale based on controllable aerosol generation and collection was developed in this study. In this technique, by using commercial differential electrostatic mobility analyzer (DMA) and calibrated condensation particle counter (CPC), monodisperse aerosol particle with known concentration was initially generated. Then for quantitatively transforming the aerosol particles to the liquid, an aerosol particle collection system was designed and developed by hydrodynamic (CFD) simulations and experiment conducting, and crucial parameters of the collection system, e.g. the nozzle diameter of the aerosol particle outlet, the distance from the nozzle to the liquid surface, and the state of the liquid interface, were investigated and optimized. Under the optimized collected parameters, the collection efficiency for aerosol particles of the newly-developed system could reach over 90%. Because the PNC in aerosol is SI-traceable, combined with the obtained collection efficiency and collection time, the PNC in the collection liquid with could be obtained finally and trace to SI unit. Using this technique, two kinds of PNC-CRMs with nominal sizes of 100 and 500 nm were developed successfully, where, certified values were (7–9) × 106 particles/mL and 1.7 × 106 particles/mL, and standard uncertainties are 4.2%.

Unlocking the nanoparticle emission potential: a study of varied filaments in 3D printing.

This study investigates nanoparticle emission during 3D printing processes, assessing various filament materials' impact on air quality. Commonly used 3D printers, including both filament and resin-based types, were examined. The study's scope encompasses diverse filament materials like ABS (acrylonitrile butadiene styrene), PLA (polylactic acid), PETG (polyethylene terephthalate glycol), ASA (acrylonitrile styrene acrylate), TPU (thermoplastic polyurethane), PP (polypropylene), nylon, and wood-based variants, alongside three types of resins. The research delves into the relationship between the type of material and nanoparticle emissions, emphasizing temperature's pivotal role. Measurement instruments were employed for nanoparticle quantification, including an engine exhaust particle sizer spectrometer, condensation particle counter, and nanozen dust counters. Notably, results reveal substantial variations in nanoparticle emissions among different filament materials, with ASA, TPU, PP, and ABS showing considerably elevated emission levels and characteristic particle size distribution patterns. The findings prompt practical recommendations for reducing nanoparticle exposure, emphasizing printer confinement, material selection, and adequate ventilation. This study offers insights into potential health risks associated with 3D printing emissions and provides a basis for adopting preventive measures.

Absolute protein quantification based on calibrated particle counting using electrospray-differential mobility analysis

The traceability of in vitro diagnostics or drug products is based on the accurate quantification of proteins. In this study, we developed an absolute quantification approach for proteins. This method is based on calibrated particle counting using electrospray-differential mobility analysis (ES-DMA) coupled with a condensation particle counter (CPC). The absolute concentration of proteins was quantified with the observed protein particle number measured with ES-DMA-CPC, and the detection efficiency was determined by calibrators. The measurement performance and quantitative level were verified using two certificated reference materials, BSA and NIMCmAb. The linear regression fit for the detection efficiency values of three reference materials and one highly purified protein (myoglobin, BSA, NIMCmAb and fibrinogen) indicated that the detection efficiency and the particle size distribution of these proteins exhibited a linear relationship. Moreover, to explore the suitability of the detection efficiency-particle size curve for protein quantification, the concentrations of three typical proteinaceous particles, including two high molecular weight proteins (NIST reference material 8671 and D-dimer) and one protein complex (glutathione S-transferase dimer), were determined. This work suggests that this calibrated particle counting method is an efficient approach for nondestructive, rapid and accurate quantification of proteins, especially for measuring proteinaceous particles with tremendous size and without reference standards.

Investigation into Detection Efficiency Deviations in Aviation Soot and Calibration Particles Based on Condensation Particle Counting

Aviation soot constitutes a significant threat to human well-being, underscoring the critical importance of accurate measurements. The condensation particle counter (CPC) is the primary instrument for quantifying aviation soot, with detection efficiency being a crucial parameter. The properties of small particles and the symmetry of their growth pathways are closely related to the detection efficiency of the CPC. In laboratory environments, sodium chloride is conventionally utilized to calibrate the CPC’s detection efficiency. However, aviation soot exhibits distinctive morphological characteristics compared to the calibration particles, leading to detection efficiencies obtained from calibration particles that may not be applicable to aviation soot. To address this issue, a quantitative study was performed to explore the detection efficiency deviations between aviation soot and calibration particles. The experiment initially utilized a differential mobility analyzer to size select the two types of polydisperse particles into monodisperse particles. Subsequently, measurements of the separated particles were performed using the TSI Corporation’s aerosol electrometer and a rigorously validated CPC (BH-CPC). These allowed for determining the detection efficiency deviation in the BH-CPC for the two types of particles at different particle sizes. Furthermore, the influence of the operating temperature of the BH-CPC on this detection efficiency deviation was investigated. The experimental results indicate a significant detection efficiency deviation between aviation soot and sodium chloride. In the range of 10–40 nm, the absolute detection efficiency deviation can reach a maximum of 0.15, and the relative deviation can reach a maximum of 0.75. And this detection efficiency deviation can be reduced by establishing a relevant relationship between the detection efficiency of the operating temperature and the calibration temperature. Compared to the saturated segment calibration temperature of 50 °C, the aviation soot detection efficiency is closer to the sodium chloride detection efficiency at the calibration temperature of 50 °C when the saturated segment operates at a temperature of 45 °C. These studies provide crucial theoretical guidance for enhancing the precision of aviation soot emission detection and establish a foundation for future research in monitoring and controlling soot emissions within the aviation sector.

Influence of a large commercial airport on the ultrafine particle number concentration in a distant residential area under different wind conditions and the impact of the COVID-19 pandemic

Exposure to ultrafine particles has a significant influence on human health. In regions with large commercial airports, air traffic and ground operations can represent a potential particle source. The particle number concentration was measured in a low-traffic residential area about 7 km from Frankfurt Airport with a Condensation Particle Counter in a long-term study. In addition, the particle number size distribution was determined using a Fast Mobility Particle Sizer.The particle number concentrations showed high variations over the entire measuring period and even within a single day. A maximum 24 h-mean of 24,120 cm−3 was detected. Very high particle number concentrations were in particular measured when the wind came from the direction of the airport. In this case, the particle number size distribution showed a maximum in the particle size range between 5 and 15 nm. Particles produced by combustion in jet engines typically have this size range and a high potential to be deposited in the alveoli. During a period with high air traffic volume, significantly higher particle number concentrations could be measured than during a period with low air traffic volume, as in the COVID-19 pandemic.A large commercial airport thus has the potential to lead to a high particle number concentration even in a distant residential area. Due to the high particle number concentrations, the critical particle size, and strong concentration fluctuations, long-term measurements are essential for a realistic exposure analysis.

Solid Particle Number (SPN) Portable Emission Measurement Systems (PEMS) for Heavy-Duty Applications

A heavy-duty engine is homologated in a test cell. However, starting with Euro VI regulation, the in-service conformity is controlled with the engine installed in the vehicle using portable emission measurement systems (PEMS). In Europe, the application of solid particle number (SPN) PEMS started in 2021 for compression ignition (diesel) vehicles and in 2023 for positive ignition vehicles, thus including those operating with compressed natural gas (CNG). Even though today only particles with sizes > 23 nm are regulated, the Euro 7 proposal includes particles > 10 nm. There are not many studies on the accuracy of the SPN PEMS, especially for heavy-duty applications. In this study, PEMS measuring > 23 and >10 nm from two instrument manufacturers were compared with laboratory-grade instruments. The particle detector of one PEMS was a condensation particle counter (CPC), and of the other a the diffusion charger (DC). The results showed the robustness and good accuracy (40% or 1 × 1011 #/kWh) of the PEMS for ambient temperatures from −7 °C to 35 °C, active regeneration events, different fuels (Diesel B7, HVO, and CNG), different test cycles, cold start or hot engine operations, and high exhaust gas humidity content. Nevertheless, for the DC-based PEMS, sensitivity to pre-charged urea particles was identified, and for the CPC-based PEMS, sensitivity to pressure changes with one vehicle was nnoticed. Nevertheless, the results of this study confirm that the PEMS are accurate enough to measure even the stricter Euro 7 limits.

In-vehicle ultrafine and fine particulate matter exposures during commuting in a South Asian megacity: Dhaka, Bangladesh

We measured ultrafine particle number concentration (PNC) and fine particulate matter mass concentration (PM2.5) levels in public buses and private cars under three conditions: windows open, windows closed with air recirculation off, and windows closed with air recirculation on in Dhaka, Bangladesh—an extremely polluted megacity in South Asia. We collected measurements on ∼10 repeated round trips on unique days for each selected transportation mode, covering various routes that spanned multiple arterial roads over several months (January to March 2020 and November to December 2020) and different times of the day to account for the variability in traffic and meteorological conditions. We used a condensation particle counter (CPC) to measure PNC and a PurpleAir sensor to measure PM2.5 mass concentrations. We applied corrections to the raw data and analyzed quality-assured data to investigate exposure differences across modes, pollutants, locations, and times. Public buses and private cars with open windows had mean PNC levels of 112,000 # cm−3 and 117,000 # cm−3, approximately 5–6 times higher than the mean urban background level of around 20,000 # cm−3. PM2.5 levels in these vehicles were approximately ∼100 μg m−3, about 20% higher than the urban background PM2.5 level of 85 μg m−3. With closed windows and air recirculation off, concentrations were 15% lower for PNC and 10% lower for PM2.5. Under closing windows and keeping air recirculation on, mean PNC and PM2.5 levels were 60,000 # cm−3 and 70 μg m−3, respectively, representing a 50% reduction for PNC and a 30% reduction for PM2.5 compared to open windows. Our findings suggest that commuters in public buses and private cars with open windows have higher and similar exposure levels, whereas those commute in private cars with closed windows and air recirculation on have lower exposure levels.

Integrated microfluidic-based ultrafine water condensation particle counter (UWCPC) for monitoring of airborne nanoparticle generation and growth mechanisms

This study reports a newly developed condensation particle counter for nanoparticle source tracking, growth mechanism analysis, and wide area nanoparticle monitoring.

Calibration and Experimental Study of a Self-Developed Particle-Number Measurement Instrument

To accurately evaluate the size and distribution characteristics of the emission particles exhausted from in-use motor vehicle engines, we independently developed a condensation particle counter (CPC) known as BHCPC. It was calibrated by conducting the calibration procedures stated in the International Standard ISO 27981. After calibration, we conducted on-site measurements and offline sampling analysis of soot particles exhausted from different engines at a motor vehicle inspection center. The calibration results show that the detection efficiency is 90% when the particle diameter is 20.6 nm and the startup response time of the instrument is 3.53 s. The experiment results show that the self-developed BHCPC demonstrates good consistency in measuring particle-number concentration (PNC) in motor vehicle exhaust, with significant count fluctuations only occurring when PNC is higher than 25,000 P/cc. Under idle conditions, motor vehicles compliant with China VI emission regulations exhibit markedly lower exhaust emission PNC compared to those adhering to China IV emission regulations. Moreover, the results obtained from the offline electron microscope analysis show that fuel content in particle samples significantly decreases as engine speed increases, and a similar variation was also found in particle size. The micro-characteristics of the particle can give potential support to the combustion diagnostics.

Technical note: The Graetz problem at small Peclet number and its application to sizing condensation particle counters

We extend to small Peclet number Pe the familiar high-Pe solution to the Graetz problem of heat/mass transfer in a tube with parabolic flow with a wall temperature discontinuity at an axial position z = 0. Retaining diffusion in the axial direction results only in slight shifts in the eigenfunctions describing the problem. This enables the characterization of the saturation field S by separation of variables, which we implement for Pe = 0, 0.1, 0.25. Calculations based on discretization of the transport partial differential equations are also used to analyze the problem at Pe up to 5. As Pe tends to 0, the heat and mass transfer problems are both described by the same dimensionless function θ(z,r) of the axial and radial coordinates z and r. S then depends on the single quantity θ, and its maximum value Smax is exactly the same along all streamlines. This would result in sharp activation curves in a hypothetical low-Pe condensation particle counter, similarly as in the special circumstance when the ratio Le between heat and mass diffusivities is unity. Calculations are run to determine how the radial uniformity of Smax is degraded at increasing Pe. When accounting for axial diffusion, Smax at the wall is independent of Pe or Le. The commonly considered high Pe limit fails to satisfy this requirement, and therefore predicts an incorrect Smax at distances from the wall discontinuity small compared to Pe−1/2.

Design of a sheathed water condensation particle counter with variable saturation ratio

We consider a particle condensation device where a cold aerosol enters at one open end of a tube. The wall of the tube is porous beyond a certain section. A stream of cold air is injected radially and symmetrically through an initial focusing region of the porous wall, and a stream of warm humid air with a saturation ratio S is injected in a condensation region further downstream. The configuration offers several advantages over existing water condensation particle counters (WCPCs). First, S may be varied by mixing a dry gas stream with a humid stream prior to their passage through the porous tube wall. Second, radial entry of the humidified flow accelerates the penetration of the vapor into the core of the tube, such that the maximal saturation ratio is reached within axial distances comparable with the tube radius. Third, the aerosol is partially confined within the tube core by the radially entering dry and humid gases. The particles then sample the relatively uniform saturation field near the tube axis, resulting in sharp responses of the activation probability versus particle diameter. Calculations with various combinations of axial and radial Reynolds numbers are carried out in search of conditions resulting in the smallest possible variation of the maximal supersaturation reached along the various flow streamlines.

Numerical simulation on the effects of flow parameters on the detection performance of a self-developed condensation particle counter

Numerical simulation on the effects of flow parameters on the detection performance of a self-developed condensation particle counter

Development of an optical particle number sensor based on continuous wave laser-induced incandescence

In this work, the development of a new particle counting sensor based on continuous-wave laser-induced incandescence is described. We demonstrate the sensor, which makes use of a focussed laser beam emitted by a compact laser diode, as an alternative device to established laboratory techniques to count soot particles. Simulations help understanding the cause–effect relationships based on known theory with the implementation of specific laser beam characteristics that influence the absorption process. The main goal of this work was to demonstrate the sensor’s ability to determine the soot particle number concentration of a test aerosol. This has been confirmed through a comparison with established laboratory instruments, like scanning mobility particle sizer or condensation particle counter. The observed size dependency of the laser induced incandescence sensor’s detection efficiency was successfully corrected with prior knowledge of the investigated particle size distribution. Furthermore, the sensor’s detection limit with respect to the particle diameter was determined to be well below 100 nm with a dependency on the applied laser power.

Sulfuric Acid Nucleation Potential Model Applied to Complex Reacting Systems in the Atmosphere

AbstractAtmospheric aerosol particles impact Earth's radiation balance by acting as seeds for cloud droplet formation. Over half of global cloud seed particles are formed by nucleation, a process where gas‐phase compounds react to form stable particles. Reactions of sulfuric acid (SA) with a wide variety of atmospheric compounds have been previously shown to drive nucleation in the lower troposphere. However, global climate models poorly predict particle nucleation rates since current nucleation models do not describe nucleation for systems containing tens to hundreds of precursor compounds. The nucleation potential model (NPM) was recently developed to model SA nucleation of complex mixtures by measuring an effective base concentration using a 1‐nm condensation particle counter. This technique for estimating particle nucleation rates can be deployed at a much higher spatial and temporal resolution than current methods which require detailed knowledge of all nucleation reactions and measurements, typically using a mass spectrometer, of all nucleation precursor gases. This work expands NPM by showing that this model can capture enhancement and suppression of SA nucleation rates within a complex mixture of organic and inorganic acids, ambient air, and across a range of atmospherically relevant relative humidities. In addition, an expression for calculating atmospheric nucleation rates was also derived from the NPM. Ultimately, NPM provides a simple way to measure and model the extent compounds in a complex mixture enhance SA nucleation rates using a condensation particle counter.

Pressure-dependent performance of two CEN-specified condensation particle counters

Abstract. One of the most important parameters to quantify an aerosol is the particle number concentration. Condensation particle counters (CPCs) are commonly used to measure the aerosol number concentration in the nanometer size range. To compare the data from different measurement stations and campaigns, it is important to harmonize the instrument specifications, which is why the CEN/TS 16976:2016 technical specification was introduced for CPCs. Therein, the parameters of the CEN CPC are specified for standard pressure and temperature. However, CEN CPCs are used in various surroundings, on high mountains or on airplanes, where they are exposed to low-pressure conditions. Here, we present the pressure-dependent performance (including the concentration linearity and counting efficiency) of two different models of CEN CPCs, the Grimm 5410 CEN and the TSI 3772 CEN. We found that their performance at 1000 and 750 hPa was in accordance with the CEN technical specifications. Below 500 hPa, the performance decreased for both CPC models, but the decrease was different for the two models. To gain insight into the performance of the two CPC models, we performed a simulation study. This study included simulations of the saturation profiles and calculations of internal particle losses within the CPCs. The simulations reproduced the overall performance decrease with decreasing pressure and reveal that the internal structure of the CPC has a significant influence on the performance. We anticipate our publication to provide a deeper understanding of the counting efficiency of CPCs and their pressure dependence. Our findings might be a starting point for new standards that include the pressure-dependent performance, or they could help in designing new CPCs.

Experimental investigation of performance and soot emissions of oxygenated fuel blends in a small aero engine

Recent studies show that mixing jet fuel with oxygenated fuels has an impact on exhaust gas soot formation. Soot particles are an environmental hazard with an impact on air quality around airports, and possibly influencing ice crystal nucleation, leading to contrail and ice cloud (cirrus) formation. These ice clouds significantly warm up the atmosphere by reflecting heat radiation back to Earth and, at the same time, being transparent to incoming sunlight. Many investigations concentrate on reducing aviation’s CO2 footprint, but only a few account for reducing soot emissions in aero engines. This study examines the potential of blending Jet A-1 with oxygenated fuels to decrease soot particle formation in aero engines. For this, blends with 5 vol% and 20 vol% of ethanol, and 5 vol% of a polyoxymethylene dimethyl ether 3–5 mix (OME3-5 mix) are investigated in an Allison 250-C20B turboshaft engine with the help of a condensation particle counter (CPC). The results show tendencies in soot particle reduction, which, in most cases, is larger than the volumetric percentage of the oxygenated fuel within the blend.

Characterization of size-resolved effective density of atmospheric particles in an urban atmosphere in Southern China

Effective density (ρeff) is one of the most important physical properties of atmospheric particles, providing important references in exploring the emissions and aging processes of fresh particles. In this study, a combined system of differential mobility analyzer, centrifugal particle mass analyzer, and condensation particle counter was used to periodically measure the ρeff of atmospheric particles in Shenzhen from Oct. 2021 to Jan. 2022. Results showed that the ρeff of particles with various size presented a bimodal distribution, which could be divided into main density (ρm, main peak, corresponding to relatively dense particles after aging) and sub density (ρs, sub peak, corresponding to fresh particles). The occurrence frequencies of ρs of particles with diameters of 50 and 80 nm were less than 20%, but were as high as about 40% of that with diameters from 120 to 350 nm. The ρm showed increasing trend with the size of particles, while ρs decreased as the increasing of the size of particles. The ρeff on pollution day varied significantly with chemical compositions. The increasing of the proportion of sulfate could promote the increasing of ρeff, while black carbon and organic matter caused opposite effects, which may be related to various factors, including the difference of the material density and morphology of various chemical components. The ρeff of 50, 80 and 120 nm particles decreased considerably during the new particle formation event, indicating that organic condensation was an important contributor to new particle growth.

Traceable methods for calibrating condensation particle counters at concentrations down to 1 cm−3

The concentration of nanometer-sized particles is frequently measured in terms of particle number concentration using well-established measuring instruments, such as condensation particle counters (CPCs). Traceability for these measurements can be achieved by means of calibration against a reference aerosol electrometer starting at concentrations >1000 cm−3. Here, two independent methods for extending traceability down to 1 cm−3 are described. The first method relies on a custom-made, reference optical particle counter while the second method combines electrometer measurements with a series of dilution steps. An inter-comparison of the two methods was carried out using polystyrene spheres with a nominal diameter of 100 nm in the concentration range 1 cm−3–100 cm−3. A CPC Model 3752 (TSI Inc, USA) was used as transfer standard. The obtained results showed a deviation of 1%–4% between the two methods, which was in agreement with the stated uncertainties.

Condensation particle counters: Exploring the limits of miniaturisation

The measurement of airborne particles continues to attract increased interest for the detection and characterisation of air pollution, emissions, fire detection, occupational and climate impacts. Concerted efforts have reduced the size and cost of optical counters that have enabled widespread sensor deployment. Currently the World Health Organisation (WHO) enforces particle regulations that are mass-based which has resulted in an influx of low-cost portable optical particle counters (OPCs) calibrated to mass standards and widely utilised for research and personal monitoring. However, OPCs are incapable of measuring particles with diameters dp≲ 300 nm which misses ultrafine particles (≤ 100 nm) that often represent the majority of particles by number concentration. Condensation particle counters (CPCs) capable of measuring ultrafine particle number concentration with high instrument sensitivity, accuracy and precision have recently been targeted for miniaturisation.Herein, we explore the limitations of the miniaturisation of a CPC growth chamber (CPC-GC). Results presented in this work use water, but equivalent expressions can be obtained for other working fluids or design criteria using the same methods. Scaling analysis considers phenomenological constraints of supersaturation, heat transfer, particle penetration and droplet growth to establish limits during miniaturisation.The results showed that optimal thermal and saturation conditions are similar where the optimum device aspect ratio is L∗≥Lmin,s∗= 1.68 Re + 7.98 and L∗≥Lmin,th∗= 1.78 Re + 8.02 respectively. L∗ is the non-dimensional aspect ratio and Lmin∗ is the minimum non-dimensional device length required as a function of the flow Reynolds number Re. Higher Reynolds numbers lead to a convection-dominated regime, where the saturation and temperature profiles take a parabolic shape. As the Reynolds number approaches unity, the reduced mass and thermal Péclet numbers result in vapour and heat diffusing upstream of the condenser, creating ellipsoidal saturation and temperature profiles. To achieve a satisfactory performance, the heat and mass transport within the CPC-GC must be convection-dominated, leading to a minimum value of Re ≳2. Desired penetration P≥0.9 for particles with an initial diameter dpinit=10nm is achieved by designs with an aspect ratio, L∗≤Lmax,p∗= 2.5 Re. Together, these constraints define an allowable range of aspect ratios for a CPC-GC as a function of the Reynolds number.The final size of the grown droplets can be controlled by varying the interaction residence time τint, defined as the time a particle spends in the supersaturation profile. Having defined a target final droplet size for optical detection, and hence having fixed τint, the aspect ratio necessary to achieve the desired growth is a function of the Reynolds number and of the dimensional radius of the CPC-GC (Ricpc) according to: Lgrowth∗=γRe/(Ricpc)2 with γ= 2τintν, where ν is the kinematic viscosity of air. Selecting a value of Ricpc such that the line for Lgrowth∗ falls in the centre of the allowable operating region defined above will optimise the dimensional CPC-GC for the selected design criteria.Limits from this model were used to realising a prototype successfully tested experimentally against a reference commercial CPC within a laboratory environment. The outcome of the present work enables designers and researchers with a toolkit to optimise the next generation of high performance miniaturised CPC-GC designs.