Silver Content Research Articles

Highly efficient removal of radioactive iodine anions by nano silver modified activated carbon fiber

Radioactive iodine anion wastewater is generated during the operation of nuclear facilities. Efficiently adsorbing and removing radioactive iodine is crucial for the sustainable development of nuclear energy. A potential adsorbent, nano silver-loaded activated carbon fiber (Ag@ACF), was prepared through hydrothermal synthesis and high-temperature vacuum reduction for the efficient removal of iodide anions. The as-prepared Ag@ACF composite has been comprehensively characterized, with silver nanoparticles uniformly distributed on the surface and pore walls of the Ag@ACF, enhancing the adsorption sites for iodine anions. The adsorption performance of Ag@ACF towards iodine anions was evaluated through column and batch experiments, varying silver concentration, adsorbent dosage, pH, contact time, and competing anions. Ag@ACF demonstrated high water stability and a low desorption rate of iodine anions. At a pH of 2, Ag@ACF exhibited a maximum adsorption capacity for iodine anions of 372 mg/g, surpassing most other adsorbents and showing promise for engineering applications. Adsorption kinetics and isotherm analysis indicated that the adsorption process of Ag@ACF primarily involved monolayer homogeneous chemisorption, resulting in the formation of stable AgI. These results suggest that Ag@ACF could serve as a potential adsorbent for removing iodine from radioactive wastewater.

The Effect of Nanosilver-Based Preparation Added to Litter on Silver and Antagonistic Elements Content in Broiler Tissues and Organs

Nanosilver has a wide range of applications in many industries, including animal production. Its beneficial effects resulting from, among others, antibacterial properties are known; however, some concerns remain related to safety of its use and possible accumulation in the environment and all its components. This study aimed to analyze the content of silver and antagonistic elements (copper, selenium, zinc) in breast and thigh muscles, abdomen skin, liver, lung and blood serum of broilers exposed to a nanosilver-based preparation added to litter. Ross 308 broilers were divided into three groups: control and two experimental (84 birds in each) differing by the amount of preparation addition. The study lasted 24 days, after which the birds were slaughtered and the mentioned samples were collected for laboratory analyses using atomic absorption spectroscopy. An application of preparation based on nanosilver caused an increase in Ag content in chickens’ liver, lung and abdomen skin. Cu content decreased in all experimental groups, except for abdomen skin, while Zn content increased in most cases compared to the control. No clear decrease of the increasing tendency was found for Se. It did not demonstrate an antagonism with respect to the content of Cu, Se and Zn in examined samples.

Making money out of making money in ancient Athens

AbstractThe observed weights of ancient coins are usually less than the nominal “ideal” weights of the coin standards to which they belong because state authorities took a fee—“seigniorage”—for minting coins to cover costs and to make a profit. The basis for calculating the amount taken by the state and the way it administered manufacture are not well understood. Here we analyze the weights of 1344 of the earliest coins of Athens (c. 550–479 bce). We reveal a parabolic relationship between the cost of the silver and the weights of the coins whereby a progressively higher proportion was taken as the denomination decreased, meaning that the smaller the coin, the larger was the proportion of silver taken from it. There was tight control of the minting process and mathematical sophistication in precisely adjusting the silver content from the first introduction of coinage. It also made minting a profitable business. Changes in minting practice can be detected with the introduction of the Athenian “owl” coins, when the percentage of silver taken by the state increased and the spread of weights widened to include coins weighing more than the nominal weight. The latter indicates a significant shift toward monetization of the economy.

Silver nanoparticles as a new sintering additive for the fabrication of YAG:Ce optical luminescent ceramics

AbstractIn this study, silver nanoparticles (NPs) were considered for the first time as a sintering additive in the manufacture of YAG:Ce luminescent ceramics. The influence of the addition of silver NPs on the sintering kinetics of ceramics was investigated. It was found that the addition of Ag NPs in the concentration range of 0.027–0.44 wt% does not result in the formation of secondary phases in YAG:Ce ceramics. It was demonstrated that the light transmission of ceramics is dependent on the concentration of Ag NPs. The use of NPs additive has made it possible to increase the light transmission of ceramics compared with the reference sample without sintering additives. The combination of two sintering additives, TEOS and silver NPs, enables the achievement of enhanced optical transparency in ceramics compared to the individual application of sintering additives. At an optimal silver concentration of 0.11 wt%, in combination with 0.5 wt% TEOS, a ceramic light transmission value of 77% was attained. The study has identified a correlation between the luminescence intensity of YAG:Ce ceramics and the concentration of silver NPs. It was observed that the utilization of low concentrations of the Ag additive had negligible impact on the luminescence properties, whereas the introduction of high concentrations of Ag NPs led to a deterioration in the luminescence and optical transparency of the ceramic.

Aerosol Inhalation Delivery of Ag Nanoparticles in Mice: Pharmacokinetics and Antibacterial Action.

The aerosol inhalation delivery of composite particles consisting of Ag nanoparticles enveloped by polyvinylpyrrolidone was investigated in experiments with mice. An ultrasonic nebulizing system was created for the generation of aerosols with a mean diameter and mass concentration of 700 ± 50 nm and 65 ± 5 mg/m3, respectively. The mass fraction of Ag in the composite particles was α = 0.061. The aerosol delivery was performed in a whole-body chamber with an exposition time of 20 min. Pharmacokinetic measurements were taken and the silver concentrations in the blood and lungs of the mice were measured as a function of time after exposition by means of electrothermal (graphite furnace) atomic absorption spectrometry. The inhalation dose and other pharmacokinetic parameters were determined. The antibacterial effect of aerosolized silver was assessed for mice infected with Klebsiella pneumoniae 82 and Staphylococcus aureus ATCC 25953. The survival rate of the infected mice after the aerosol exposure demonstrated the high antibacterial efficiency of Ag nanoparticles after inhalation delivery.

Clove bud extract mediated green synthesis of bimetallic Ag–Fe nanoparticles: Antimicrobial, antioxidant and dye adsorption behavior and mechanistic insights of metal ion reduction

Metal nanoparticle synthesis by metal ion reduction from plant extract has paid immense attention to researchers owing to its low cost, easy synthesis and eco-friendly nature compared to other biological methods. Compared to monometallic nanoparticles, syntheses of bimetallic nanoparticles have great importance due to the possibility of better performance of bimetallic nanoparticles compared to their monometallic counterpart. To explore this possibility, we synthesized bimetallic Ag–Fe nanoparticles of different compositions using aqueous phase co-reduction of Ag+ and Fe3+ metal ions in different ratios by clove (Syzygium aromaticum) flower bud extract. Prepared nanoparticles were characterized by Ultraviolet–visible spectroscopy, powder X-ray diffraction and Scanning Electron Microscopic studies, etc. All bimetallic nanoparticles exhibited multifaceted applications as antimicrobial agents, antioxidants and dye adsorbents. Among the different nanoparticles, bimetallic nanoparticles having Ag–Fe ratio 80:20 exhibit better performance for antimicrobial and dye adsorption activity than mono as well as other bimetallic nanoparticles. As depicted by the powder X-ray diffraction study, the synergy between metals is attributed to the prevention of oxidation of silver to silver oxide in the presence of iron. However, antioxidant activity is directly related to silver content as both silver and silver oxide exhibit almost similar antioxidant properties. The synergy between the metals in bimetallic nanoparticles provided the opportunity to enhance the activity of nanomaterials for various applications along with lowering the cost. Besides the synthesis and activity study of bimetallic nanoparticles, we tried to provide theoretical evidence for the mechanism of metal ion reduction by Eugenol (a major phytochemical present in the clove extract). Structural optimization and thermodynamic parameter calculation using DFT methods suggest that eugenol is preferred to oxidize itself and theoretically calculated reduction potential is ∼ -3.40V at 300K in the gaseous phase.

Degradation of Paracetamol in Distilled and Drinking Water via Ag/ZnO Photocatalysis under UV and Natural Sunlight

The present study demonstrates the synthesis and application of Ag/ZnO powder films (thickness of 4 μm) as photocatalysts for natural sunlight and ultraviolet (UV, 315–400 nm) irradiation. The synthesis procedure is simple and eco-friendly, based on the photo-fixation of silver ions onto commercial ZnO powder via UV illumination for the first time. The photocatalytic efficiency of the newly developed films is evaluated through degradation of paracetamol in distilled and drinking water. Our experimental evidences show that the Ag/ZnO nanostructure films are more active than pristine ZnO films in the photodegradation process. Namely, the photocatalytic efficiency of the films modified with 10−2 M concentration of silver ions achieve the highest degradation (D) percentages for paracetamol in both types of water (Ddistilled = 80.97%, Ddrinking = 82.5%) under natural sunlight. Under UV exposure, the degradation percentages are slightly lower but still higher than those achieved by pure ZnO films (Ddistilled = 53.13%, Ddrinking = 61.87%). It is found that the photocatalytic activity grows in direct proportion to the concentration of Ag+ ions: ZnO < Ag 10−4/ZnO < Ag 10−3/ZnO < Ag 10−2/ZnO. Scanning electron microscopy, X-ray diffraction, X-ray photoelectron spectroscopy, UV–vis diffuse reflectance and photoluminescence spectroscopy are used to characterize the as-prepared ZnO and Ag/ZnO nanostructures. The improved photocatalytic performance of the Ag/ZnO films is mostly attributed to the combination of excited electron transfer from ZnO to Ag and the inhibition of photogenerated electron–hole pair recombination. Furthermore, Ag/ZnO nanostructure films can retain their photocatalytic activity after three cycles of use, highlighting their potential practical application for the treatment of pharmaceutical wastewater in real-world scenarios where natural sunlight is often more readily available than artificial UV light.

All wet preparation of Ag-As33S67 thin films by silver ions photodiffusion from silver nitrate solution

Amorphous As33S67 thin films were prepared by spin-coating method from n-butylamine based glass solution as well as by thermal evaporation. Thin films were doped by silver ions from a solution of silver nitrate in dimethylsulfoxide. The influence of illumination on the photodoping kinetics was studied in dependence on the deposition technique and thermal pre-history of solution processed As33S67 thin films. Doped thin films maintained good optical quality, decreased optical bandgap and increased refractive index were observed with increasing silver content. Highly doped thin films remained amorphous. A hypothesis explaining observed significant differences in doping mechanisms between solution processed and thermally evaporated samples was proposed based on structural differences and organic residua content. Described procedure simplifies the silver doping technique and our findings proved, that it is suitable for all wet processes, thus excluding the necessity for vacuum deposition of solid silver film.

FUNCTIONAL MATERIALS FROM PAPER WASTES. V. SYNTHESIS AND CHARACTERIZATION OF HYBRID NANOCOMPOSITES OF POWDER CELLULOSES ISOLATED FROM WASTE PAPER AND SILVER NANOPARTICLES

Hybrid nanocomposites of powder celluloses (PCs) isolated from newsprint and cardboard waste containing silver nanoparticles (NPs) were synthesized using the diffusion-reduction method. The reduction of silver from solutions of its salt was carried out under heterogeneous conditions using trisodium citrate as a reducer. Molar ratio (MR) of PC/silver varied from 20 to 40. The mechanism of silver NPs formation and stabilization in the reduction process was considered. The hybrid nanocomposites were studied by IR-Fourier spectroscopy, high-resolution 13С NMR spectroscopy in a solid phase, wide-angle X-ray scattering, scanning electron microscopy (SEM), and energy-dispersive X-ray microanalysis (EDRA). It was shown that the silver particles had spherical shape and their size on the surface of the PC was mostly less than 100 nm. The silver content in the nanocomposites ranged from 1.2 to 7.3 wt.%. The preparation of NPs did not change in the structural modification of cellulose I after the reaction. During the modification of PCs with silver nanoparticles, the cellulose matrix was involved in a redox process, which was accompanied by the formation of new intermolecular bonds between the NPs and the matrix.

Ampacet launches ProVital™+ GermsClean, medical-grade antimicrobial masterbatch

Ampacet ProVital+ Germsclean is an additive developed to protect plastic components in healthcare facilities from the proliferation of microorganisms. It is claimed to offer excellent performance and protection from a wide spectrum of pathogens, with a lower addition rate than traditional competitive solutions and with a very low silver content, limiting discoloration.

A programmed surface on dental implants sequentially initiates bacteriostasis and osseointegration.

Osteogenesis surrounding dental implants is initiated by a series of early physiological events, including the inflammatory response. However, the persistence of an anti-infection surface often results in compromised histocompatibility and osseointegration. Here, we presented a programmed surface containing both silver nanoparticles (AgNPs) and silver ions (Ag+) with a heterogeneous structure and time-dependent functionalities. The AgNPs were located at the surface of the heparin-chitosan polyelectrolyte coating (PEM), whereas Ag+ was distributed at both the surface and inside of the coating under optimized conditions (pH=4). The optimized coating (Ag-4) exhibited potent bactericidal activity at the early stage (12 and 24h after inoculation) and a sustained antibacterial efficacy in the subsequent stage (one or two weeks), as it gradually depleted. Furthermore, compared to coatings with sustained high silver concentrations in bacteria-cell coculture experiments, the degradable Ag-4 coating demonstrated improved cytocompatibility, better cell viability, and morphology over time. At a later stage (within one month), the in vivo test revealed that Ag-4-coated titanium had superior histocompatibility and osteogenesis outcomes compared to bare titanium in a bacteria-exposed environment. The programmed surface of dental implants presented in this study offers innovative ideas for sequential antibacterial effects and osseointegration.

Impact of Ag concentration in As-S-Se chalcogenide on physical, topological and resistive switching properties

Physical properties of quaternary chalcogenide Agx(As40S30Se30)100-x, glasses were analyzed. Synthesis of the studied samples x = 6 - 9 at.% Ag was performed by melt quenching in cascade regime of heating. X-ray diffraction analysis verified amorphous character of the synthesized samples. Morphological characterization was carried out using a scanning electron microscopy, and energy-dispersive X-ray mapping. The obtained results show that the density of the system increases upon silver incorporation in the glassy As40S30Se30 matrix, which is manifested through decrease of free volume percentage. Assessment of various physical and topological properties of prepared series of chalcogenide materials was done using theoretical models available in the literature. Specifically, compactness, average coordination number, constraint parameters, cross-linking density, floppy modes, number of lone–pair electrons are analyzed with addition of Ag atoms in the As40S30Se30 matrix. Average single bond energy and the mean bond energy were also discussed. The chemical bond approach model was used to study the cohesive energy of the studied Ag-containing As-S-Se samples. It is found that all studied parameters are dependent upon silver concentrations. Finally, the room-temperature memristive characteristics and compositional dependence on resistive switching properties in a wide range of Ag concentrations were examined in this paper.

Pectin encapsulated novel nanocomposite augments wound healing in Sprague Dawley rats

The complexity of the tissue remodeling process makes the treatment options for wound healing inadequate. Herein, the potential wound-healing activity of a novel nanocomposite with pectin and keratin incorporating silver nanoparticles and ferulic acid has been evaluated. Silver concentration, secondary structural stability of keratin, and the presence of ferulic acid and nano silver as a complex molecule within the nanocomposite were confirmed by XPS, CD spectroscopy, and ESI-MS analysis, respectively. The effects of the nanocomposite (NC) on cell migration and the role of apoptosis in wound healing were studied by scratch assay and (A.O./EtBr) staining, respectively. Subsequently, in vivo studies were carried out in male Sprague Dawley rats. Wound tracings measured exhibited significant wound contraction. Further, the relative gene expression of wound–healing biomarkers MMP2, MMP8, and KGF increased considerably in the 75 mg test group compared to the negative control group indicating a faster epithelialization phase of wound healing. Histopathological observations revealed remarkable skin regeneration in the test group. Altogether, the nanocomposite at 75 mg dose exhibits enhanced cell migration capability, reepithelialization and tissue remodeling activity than the standard, possibly due to the synergistic influence of the natural biomolecules. Therefore it is concluded that the NC exhibits accelerated wound healing with negligible toxicity.

2-Pyridinecarboxaldehyde-Modified Chitosan-Silver Complexes: Optimized Preparation, Characterization, and Antibacterial Activity.

The widespread prevalence of infectious bacteria is one of the greatest threats to public health, and consequently, there is an urgent need for efficient and broad-spectrum antibacterial materials that are antibiotic-free. In this study, 2-pyridinecarboxaldehyde (PCA) was grafted onto chitosan (CS) and the modified CS coordinated with silver ions to prepare PCA-CS-Ag complexes with antibacterial activity. To obtain complexes with a high silver content, the preparation process was optimized using single-factor experiments and response surface methodology. Under the optimal preparation conditions (an additional amount of silver nitrate (58 mg), a solution pH of 3.9, and a reaction temperature of 69 °C), the silver content of the PCA-CS-Ag complex reached 13.27 mg/g. The structure of the PCA-CS-Ag complex was subsequently verified using ultraviolet-visible spectroscopy, Fourier-transform infrared spectroscopy, proton nuclear magnetic resonance spectroscopy, and thermogravimetric analysis. Furthermore, three possible complexation modes of the PCA-CS-Ag complex were proposed using molecular mechanics calculations. The results of the antibacterial assay in vitro showed that the PCA-CS-Ag complex exhibited strong antibacterial activity against both Gram-positive and Gram-negative bacteria, exerting the synergistic antibacterial effect of modified chitosan and silver ions. Therefore, the PCA-CS-Ag complex is expected to be developed as an effective antibacterial material with promising applications in food films, packaging, medical dressings, and other fields.

Silver-substituted hydroxyapatite: Mechanochemical synthesis and thermal stability

Silver-substituted hydroxyapatites have been prepared by the mechanochemical method in a planetary ball mill. In order to prepare a series of samples of the Ca10−xAgx (PO4)6(OH)2−x composition, the concentration of silver was varied in the range x = 0–2. The resultant samples were characterized by means of X-ray diffraction, FTIR spectroscopy, and simultaneous thermal analysis. It was shown that the single-phase substituted hydroxyapatites were achieved with silver concentrations of up to х = 1.5. An increase in the concentration of silver results in an increase in the volume and the unit-cell parameters of crystals. At a concentration x of 2.0, the sample contains an impurity phase of silver phosphate. The thermal stability of the as-synthesized silver-substituted samples was shown to directly depend on the degree of substitution of calcium cations by silver cations. The decomposition temperature decreases as the degree of substitution increases. Upon heating of the substituted samples, silver is gradually released from hydroxyapatite with the formation of a metallic nanosized silver phase, followed by the structural transformation of the hydroxyapatite lattice into silver-substituted tricalcium phosphate at a higher temperature. In this case, the introduction of silver cations results in a decrease in the values of the lattice parameters of tricalcium phosphate, showing a non-linear dependence on the silver concentration.

Analysis of silver nanoparticles by flame atomic absorption spectrometry

AbstractIntending to rate the quality of manufactured silver nanoparticles (AgNPs) products in the context that most of the publications in this field have focused on the residual AgNPs at trace levels, the primary goal of this report is to develop a fast and facile method for the speciation analysis of synthesized AgNPs – Ag(0) and Ag(I), using liquid‐liquid extraction (LLE) combined with flame atomic absorption spectroscopy (FAAS). Ag(I) in a pH 5 buffer solution was selectively extracted into an organic phase by dithizone, re‐extracted into an aqueous phase by HNO3, and then quantified by FAAS. In contrast, AgNPs in the initial aqueous phase were digested with HNO3 and H2O2 and determined by FAAS. The synthesized AgNPs samples were analyzed, with a silver content of 25 – 5000 mgL−1 and 50 ‐ 96% of AgNPs. The mass balance for silver confirmed that the speciation analysis of AgNPs agreed with the total analysis for silver in these samples. The average recovery of the spiked samples reached 98.9 ± 1.5% (P = 0.95). The method's precision was determined via the repeatability and reproducibility of 0.027 and 0.036 mgL−1 (P = 0.95). Both AgNPs and ionic silver were diluted to the same extent and quantified in atomized silver form, leading to a similar limit of detection (LOD) and quantification (LOQ) of 0.058 mgL−1 and 0.19 mgL−1 (P = 0.95), respectively. The proposed procedure was reliable and low‐cost that barely requires too advanced instruments to analyze AgNPs products at high concentration levels.

Silver substituted cobalt zinc ferrites as magnetic antimicrobials

Silver-substituted cobalt zinc ferrite series, CoxAg0.5-xZn0.5Fe2O4 (x = 0.4, 0.3, 0.2, 0.1), is synthesized using the citrate gel method, wherein ferrite formation is achieved at 600 °C. The low-temperature crystallization results in agglomerated and porous ferrites. In this sample preparation methodology, as the silver content in the series increases, metallic silver deposits at the grain boundaries, and vacancies are created at the octahedral sites. With a further increase in silver content, the magnitude of magnetic properties decreases. Antimicrobial activity increases and further decreases with an increase in silver content. The composition Co0.4Ag0.1Zn0.5Fe2O4 exhibits both magnetic and antimicrobial behaviour. These materials can potentially be beneficial in the manufacture of removable antimicrobial agents for water purification and drug delivery systems.

Microscale Corrosion Inhibition Behavior of Four Corrosion Inhibitors (BTA, MBI, MBT, and MBO) on Archeological Silver Artifacts Based on Scanning Electrochemical Cell Microscopy.

The problem of corrosion-induced discoloration and embrittlement in silverware is a significant concern for the long-term preservation of excavated archeological silver artifacts, even after thermal restoration. The key to addressing this issue lies in the meticulous selection and evaluation of corrosion inhibitors that possess targeted corrosion inhibition capabilities. This study focuses on the evaluation of corrosion inhibitors for archeological silver artifacts using scanning electrochemical cell microscopy (SECCM) and X-ray photoelectron spectroscopy (XPS). The researchers aimed to compare the inhibition effects of four corrosion inhibitors [1,2,3-benzotriazole (BTA), 2-mercaptobenzimidazole (MBI), 2-mercaptobenzothiazole (MBT), and 2-mercaptobenzoxazole (MBO)] on a simulated Ag-Cu alloy sample and understand their mechanisms. The results showed that MBT exhibited better corrosion inhibition for microstructural regions with higher silver content due to its ability to form stable chelation structures with Ag(I). MBO exhibited better corrosion inhibition for microstructural regions with higher copper content due to its strong affinity with Cu(I). The targeted corrosion inhibition ability for the β-phase was ranked as MBO > BTA ≈ MBI > MBT, while for the α-phase the ranking was MBT > MBO > MBI > BTA. The study demonstrated the feasibility and capabilities of SECCM in the targeted screening of corrosion inhibitors for different compositions and microstructural regions in archeological metal artifacts. This study highlights the potential of SECCM in corrosion inhibitor research for archeological metal artifacts and wider applications in metal material corrosion protection.

Silver-integrated EDM processing of TiAl6V4 implant material has antibacterial capacity while optimizing osseointegration

Periprosthetic joint infections (PJI) are a common reason for orthopedic revision surgeries. It has been shown that the silver surface modification of a titanium alloy (Ti–6Al–4V) by PMEDM (powder mixed electrical discharge machining) exhibits an antibacterial effect on Staphylococcus spp. adhesion. Whether the thickness of the silver-modified surface influences the adhesion and proliferation of bacteria as well as the ossification processes and in-vivo antibacterial capacity has not been investigated before. Therefore, the aim of this work is to investigate the antibacterial effect as well as the in vitro ossification process depending on the thickness of PMEDM silver modified surfaces.The attachment of S. aureus on the PMEDM modified surfaces was significantly lower than on comparative control samples, independently of the tested surface properties. Bacterial proliferation, however, was not affected by the silver content in the surface layer. We observed a long-term effect of antibacterial capacity in vitro, as well as in vivo. An induction of ROS, as indicator for oxidative stress, was observed in the bacteria, but not in osteoblast-like cells. No influence on the in vitro osteoblast function was observed, whereas osteoclast formation was drastically reduced on the silver surface. No changes in cell death, the metabolic activity and oxidative stress was measured in osteoblasts.We show that already small amounts of silver exhibit a significant antibacterial capacity while not influencing the osteoblast function. Therefore, PMEDM using silver nano-powder admixed to the dielectric represents a promising technology to shape and concurrently modify implant surfaces to reduce infections while at the same time optimizing bone ingrowth of endoprosthesis.

Characterization and Evaluation of Silver Concentrations in Hydroxyapatite Powders.

The goal of this study is to evaluate the influence of the concentration of silver on the structural and antimicrobial in vitro properties of silver-doped hydroxyapatite powders obtained using the precipitation method. Different concentrations of silver were evaluated to assess the antimicrobial properties. X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), Raman spectroscopy, scanning electron microscopy (SEM), and dispersive energy spectroscopy (EDS) were used to characterize the powders. XRD and FTIR showed that the hydroxyapatite structure is not affected by the incorporation of silver; on the other hand, EDS showed the presence of silver in the powders. Antibacterial studies showed the efficiency of hydroxyapatite powders in inhibiting bacterial growth as silver concentration increases. According to the results, silver-doped hydroxyapatite powders are suggested for use in the prevention and treatment of infections in bone and dental tissues.