Although extensive work has been reported that micelles can induce depletion attraction between two solid spheres or a sphere and a plate, the effect of different micelles on the depletion between two soft surfaces has been rarely reported. Optical tweezers were used to measure the forces between two oil-in-water emulsions in solutions of sodium dodecylbenzenesulfonate (SDBS), cetyltrimethylammonium bromide (CTAB), and octylphenol polyoxyethylene ether with ten oxyethylene glycol ether (OP-10) at varying concentrations. When the concentration of surfactant below their critical micelle concentration (cmc), force profiles between two emulsion droplets were purely repulsive. As the concentration of SDBS or CTAB above its cmc, the attraction between like-charged O/W emulsion droplets was dominant. The coalescence of the like-charged O/W emulsion droplets is observed. For nonionic surfactants OP-10, even if the cmc had been reached, the attractive force between O/W emulsion droplets couldn’t be measured. Results shows that attractive forces between two like-charged emulsion droplets of several microns in solution can also be induced by ionic micelles and the depletion was enhanced by counterion osmotic pressure. Our work suggests that the effect of micelle-induced depletion on the force between two solid surfaces can be used to predict forces between several micrometers of emulsion droplets.