Computer Assisted Instruction (CAI) is considered as an effective teaching-learning strategy for the effective plan, written and programmed in the computer that can be run in a several computer units and allows every student computer terminal. The instruction are programmed with the implementation of a computer disc (CD) played in audio, video, gaming, drag & drop, and simulation activity of students in their own pace. In the contemporary world the CAI is not underestimated with the instructional computer value. In human body disability is observed as the difficulty of the human body function. In Learning Disability (LD) is heterogeneous disorder groups with significant difficulties in acquisition for listening, speaking, reading, writing and reasoning. This research examined the contribution of CAI on the LD students. The analysis is based on the data collected from the LD diagnosed school students. The data were collected from the Special school in Riyadh in Saudi Arabia with the data collected from 245 sample students. The experimental analysis is conducted for the experimental and control group. The analysis is conducted based on the consideration of three variable such as hand-eye co-ordination, attention and academic performance. The analysis of data expressed that through CAI model the LD student eye-hand co-ordination, attention and academic performance is improved.