Standard Compression Research Articles

Mechanical behavior of iron ore tailings under standard compression and extension triaxial stress paths

The disposal of mining tailings has increasingly focused on the use of dry stacks. These structures offer more security since they use filtered and compacted material. Because of the construction method and the heights achieved, the material that compounds the structure can be subjected to different stress paths along the failure plane. The theoretical framework considered in the design of these structures generally is the critical state soil mechanics (CSSM). However, the data in the literature concerning the uniqueness of critical state line (CSL) is still controversial as the soil is subjected to different stress paths. With respect to tailings, this question is even more restricted. This paper studies two tailings with different gradings due to the beneficial processes over extension and compression paths. A series of drained and undrained triaxial tests was conducted over a range of initial densities and stress levels. In the q-p' plane, different critical stress ratio (M) values were obtained for compression and extension stress paths. However, the critical state friction angle is very similar with a slightly higher critical state friction angle for extension tests. Curved stress path dependent CSLs were obtained in the ν-lnp' plane with the extension tests below the CSL defined in compression. Regarding the fines content, the studied tailings presented very similar M and critical state friction angle values. However, the fines content affects the volumetric behavior of the studied tailings and the CSLs on the ν-ln p' plane shift downwards with the increasing fines content for compression and extension tests. In relation to dilatancy analysis, the fines content did not present an evident influence on the dilatancy of the materials. However, different values of mean stress ratio N were obtained between compression and extension tests and can corroborate the existence of non-unique CSLs for these materials.

Self-Asymmetric Invertible Network for Compression-Aware Image Rescaling

High-resolution (HR) images are usually downscaled to low-resolution (LR) ones for better display and afterward upscaled back to the original size to recover details. Recent work in image rescaling formulates downscaling and upscaling as a unified task and learns a bijective mapping between HR and LR via invertible networks. However, in real-world applications (e.g., social media), most images are compressed for transmission. Lossy compression will lead to irreversible information loss on LR images, hence damaging the inverse upscaling procedure and degrading the reconstruction accuracy. In this paper, we propose the Self-Asymmetric Invertible Network (SAIN) for compression-aware image rescaling. To tackle the distribution shift, we first develop an end-to-end asymmetric framework with two separate bijective mappings for high-quality and compressed LR images, respectively. Then, based on empirical analysis of this framework, we model the distribution of the lost information (including downscaling and compression) using isotropic Gaussian mixtures and propose the Enhanced Invertible Block to derive high-quality/compressed LR images in one forward pass. Besides, we design a set of losses to regularize the learned LR images and enhance the invertibility. Extensive experiments demonstrate the consistent improvements of SAIN across various image rescaling datasets in terms of both quantitative and qualitative evaluation under standard image compression formats (i.e., JPEG and WebP). Code is available at https://github.com/yang-jin-hai/SAIN.

Benchmarking Lossless Still Image Codecs: Perspectives on Selected Compression Standards From 1992 through 2022

Benchmarking Lossless Still Image Codecs: Perspectives on Selected Compression Standards From 1992 through 2022

Computer Network Redundancy Reduction Using Video Compression

Due to the strong correlation between symmetric frames, video signals have a high degree of temporal redundancy. Motion estimation techniques are computationally expensive and time-consuming processes used in symmetric video compression to reduce temporal redundancy. The block-matching technique is, on the other hand, the most popular and efficient of the different motion estimation and compensation techniques. Motion compensation based on the block-matching technique generally uses the minimization of either the mean square error (MSE) or mean absolute difference (MAD) in order to find the appropriate motion vector. This paper proposes to remove the highly temporally redundant information contained in each block of the video signal using the removing temporal redundancy (RTR) technique in order to improve the data rate and efficiency of the video signal. A comparison between the PSNR values of this technique and those of the JPEG video compression standard is made. As a result of its moderate memory and computation requirements, the algorithm was found to be suitable for mobile networks and embedded devices. Based on a detailed set of testing scenarios and the obtained results, it is evident that the RTR compression technique allowed a compression ratio of 22.71 and 95% loss in bit rate reduction while maintaining sufficient intact signal quality with minimized information loss.

Evaluation of stress path and load rate effects on rock strength using compression testing data for Stanstead Granite

Compression testing schemes that induce failure in rock specimens primarily through a reduction in confining stress have become increasingly common in recent years. Despite this, the interpretation of the results from such studies are fraught with complications due to the large number of factors that can influence the outcome of such tests relative to standard compression tests that follow a loading path. Among these, unloading rate is especially significant, as it has the potential to both influence peak strength and total test time (i.e. time-dependent effects). In this study, we present a framework to convert unloading rates into equivalent loading rates to facilitate comparison with standard compression test results as well as comparisons across rock types. We then present the results of a suite of 39 compression tests, including strain-controlled standard UCS and triaxial tests, constant deviatoric stress unloading triaxial tests, diagonal stress path unloading triaxial tests, and load-controlled standard triaxial tests. Based on comparison of load-controlled and strain-controlled standard compression tests, it is concluded that strain-controlled tests produce appreciably lower peak strength values, even if relevant ISRM Suggested Methods and ASTM Standards are followed in both cases. Additionally, the different control modes produce different volumetric strain responses up to the point of peak strength. A detailed comparison of load-controlled test results from standard triaxial tests and unloading triaxial tests with failure points at σ3 ≈ 1 MPa reveals that diagonal stress path unloading tests produce comparable peak strength values to standard load-controlled tests. Although the observed trend in the constant deviatoric stress unloading triaxial test data corresponds to lower peak strength values than those obtained using standard load-controlled tests, we attribute this discrepancy to time-dependent damage effects and/or minor damage accumulation during the initial loading phase of the tests rather than to the difference in stress paths.

A Secret JPEG Image Sharing Method Over GF(2 M ) Galois Fields

With the rise of exchanges over the cloud and social networks, JPEG images have taken an important place in world image transmission and storage. In order to avoid security breaches and combat threats on the Internet, numerous JPEG image security methods have been proposed in both the academic and industrial communities. Encryption methods have been specifically designed to make JPEG images visually secure using so called crypto-compression methods. The drawback of crypto-compression is that it depends on only one secret key. Indeed, if this key is lost, so is the totality of the content of the secret original image. In this paper, we propose a secret JPEG image sharing approach. Shamir’s secret sharing scheme over Galois fields is used during the JPEG Huffman coding step, ensuring the visual security of the secret image in the compressed domain, while solving the issue of secret key loss. In addition, we also describe an eco-friendly scenario, dealing with a public shared JPEG image. In this scenario, we can obtain compressed shares because there is no need to duplicate the redundant information. According to our obtained results, our approach is fully format compliant and size preserving when compared to a standard JPEG compression of a secret original image, while ensuring the visual security of the content of the secret original image.

Performance analysis of wireless transmission of compressed images using DCT‐OFDMA system with different compression schemes

AbstractTransmitting images over an Orthogonal Frequency Division Multiplexing Access (OFDMA) system poses a significant challenge. The process entails sending a substantial amount of data, which consumes a significant amount of bandwidth. Consequently, compressing the transmitted image becomes essential to reduce the required bandwidth. The aim of this paper is to examine and analyse the wireless transmission of a compressed image via Discrete Cosine Transform (DCT‐OFDMA). A comparison is made with Discrete Fourier Transform (DFT‐OFDMA), across various subcarrier mapping schemes (localized and inter‐leaved), and different modulation schemes (16 Quadrature Amplitude Modulation (16QAM) and Quadrature Phase Shift Keying (QPSK)) using vehicular A, Stanford University Interim (SUI3), and uniform channel models. To evaluate the performance of the system, the minimum Signal‐to‐Noise Ratio (SNR) necessary to recover the transmitted compressed image is calculated. This work considers nine standard compression techniques. The results are carried out using the MATLAB simulator. According to the simulation results, the minimum SNR required to recover the transmitted compressed image was found to be 19 dB. This result was achieved when using Discrete Cosine Transform‐Loaclized‐Orthogonal Frequency Division Multiplexing Access (DCT‐LOFDMA) with QPSK modulation and set partitioning in hierarchical trees (SPIHT) compression method over the SUI3 channel model. Moreover, it was observed that the DCT‐LOFDMA and DFT‐IOFDMA systems attained equal SNR while utilizing the SPIHT_3D compression technique and QPSK modulation on the SUI3 channel model. Overall, the results suggest that the performance of DCT‐based localized OFDMA is somewhat superior to DFT‐based localized OFDMA, particularly when utilizing the SUI3 channel model and the QPSK modulation scheme. Therefore, it is feasible to transmit and receive a compressed image effectively over an OFDMA system with DCT.

Study of the generalized curves of the static and cyclic deformation, damage and fracture

Individual deformation diagrams of all materials on metal, non-metal, or composite base under static and cyclic load link stresses and strains. These diagrams are obtained in standard tensile, compression, torsion or bending tests of laboratory samples with the registration of forces and deformations of their working parts upon loading. The diagram for a single static deformation in the stress-strain coordinates in this case covers both the region of elastic deformations and the region of elastic-plastic deformation, when deformations are localized in the neck of the loaded sample up to the moment of its destruction at a critical stress level. It is shown that linear, fractional-linear and power approximation of the obtained deformation curve are widely used in the description of the obtained deformation diagrams. Direct experiments, the theory of dislocations and the statistical theory of strength confirm the priority of power approximation of considered diagrams. At the same time for all construction materials the generalized deformation diagram in relative coordinates is described by a single power equation with the individual hardening parameter which is determined experimentally or theoretically using the dependences linking data on the module of elasticity, yield stresses, strength, and ultimate plasticity of the material. Diagrams of a cyclic elastoplastic deformation in the form of loops of plastic hysteresis are recorded by analogy with static tension diagrams with «stress – strain» axes of in conditional and true relative values. The generalized deformation diagrams for a single static and cyclic loading form a scientific basis for construction of the generalized fatigue curve on the basis of deformation fracture criterion for a wide range of cycles to failure. An effective solution to the problems of strength and service life for the most complex engineering objects such as nuclear reactors, aircraft, rocket and space systems can be achieved through introduction of generalized deformation and fracture diagrams into consideration and corresponding calculations. Their significance will especially increase in the design and implementation of new unique science-intensive facilities.

Volumetricand ultrasonic properties of thiamine hydrochloride drug in aqueous solutions of choline-based deep eutectic solvents at different temperatures

Important efforts have been made over the past years to improve the drug acts, which leads to the discovery of novel drug preparations and delivery systems. The optimal design of such processes requires a molecular-level understanding of the interactions between drug molecules and biological membranes. The thermodynamic investigation provides deep and complete knowledge of interactions and the choice of appropriate and suitable production compounds in pharmaceutical fields. Particularly, the analysis of drugs + co-solvents in aqueous media is the central issue in many types of research because they exert their impact by interacting with biological membranes. This work is aimed to measure the density and speed of sound for the thiamine hydrochloride in water + deep eutectic solvents (DESs) mixtures (choline chloride/urea, choline chloride/ethylene glycol and choline chloride/glycerol) at temperature range (293.15–308.15) K. By correlation of the evaluated parameters in some standard relations, the partial molar parameters i.e. apparent molar volumes, Vφ,m, and apparent molar isentropic compression, κs,φ,m, are calculated. In addition, apparent molar isobaric expansion, Eφ,m0, and Hepler’s constant are computed from the density and speed of sound data. For fitting the experimental Vφ,m and κs,φ,m the Redlich-Meyer equation was employed that the important quantities; standard partial molar volume, Vm0, and partial molar isentropic compression, κs,m0, were obtained. The thermodynamic analysis of the studied system also plays a crucial role in the pharmaceutical industry.

Evaluation of cancer drug infusion devices prior to the implementation of a compounding robot.

Compounding robots are increasingly being implemented in hospital pharmacies. In our hospital, the recent acquisition of a robot (RIVATM, ARxIUM) for intravenous cancer drug compounding obliged us to replace the previously used infusion devices. The objective of the present study was to assess and qualify the new intravenous sets prior to their use in our hospital and prior to the implementation of the compounding robot. The ChemoLockTM (ICU Medical) was compared with the devices used previously for compounding (BD PhaSealTM, Becton-Dickinson) and infusion (Connect-ZTM, Codan Medical). The connection/disconnection of infusion devices to/from 50 mL infusion bags was tested with a dynamometer (Multitest-i, Mecmesin). Leakage contamination was visualized by a methylene blue assay and was quantified in simulated pump infusions with 20 mg/mL quinine sulfate (N = 36/group); after the analytical assay had been validated, quinine was detected by UV-spectrophotometry at 280 and 330 nm. Groups were compared using chi-squared or Mann-Whitney U tests. The connection/disconnection test showed that although all the devices complied with the current standard, there was a statistically significant difference in the mean ± standard deviation compression force (51.5 ± 11.6 for the Connect-ZTM vs. 60.3 ± 11.7 for the ChemoLockTM; p = 0.0005). Leaks were detected in 32 (29.1%) of the 110 tests of the ChemoLockTM. The contamination rates were also significantly different: 13.9% for the BD PhaSealTM versus 75.0% for the ChemoLockTM; p < 0.0001). Our results showed that the new infusion device complied with current standards. However, the presence of contamination emphasizes the need for operators to use the recommended personal protective equipment. Further studies of contamination with cancer drugs are required.

An Introduction to Point Cloud Compression Standards

The prevalent point cloud compression (PCC) standards of today are utilized to encode various types of point cloud data, allowing for reasonable bandwidth and storage usage. With increasing demand for high-fidelity three-dimensional (3D) models for a large variety of applications, including immersive visual communication, Augmented reality (AR) and Virtual Reality (VR), navigation, autonomous driving, and smart city, point clouds are seeing increasing usage and development to meet the increasing demands. However, with the advancements in 3D modelling and sensing, the amount of data required to accurately depict such representations and models is likewise ballooning to increasingly large proportions, leading to the development and standardization of the point cloud compression standards. In this article, we provide an overview of some topical and popular MPEG point cloud compression (PCC) standards. We discuss the development and applications of the Geometry-based PCC (G-PCC) and Video-based PCC (V-PCC) standards as they escalate in importance in an era of virtual reality and machine learning. Finally, we conclude our article describing the future research directions and applications of the PCC standards of today.

Komparasi Kinerja AC Kendaraan dengan Menggunakan Refrigeran R-134a, dan R-290

The development of vapor compression refrigeration systems currently depends on the issue of environmental problems related to ozone layer depletion (ODP) and global warming potential (GWP). In addition to environmental issues, low energy use is also in the spotlight of researchers. To solve the problem of refrigeration development, natural refrigeration, especially hydrocarbons, is the focus of attention. Hydrocarbons are refrigerants that have excellent properties to be natural refrigerants. This study aims to compare the performance of refrigerant R-134a with R-290. The research used a standard vapor compression refrigeration system with a TEV-type expansion valve. The system performance is seen through compression, refrigeration effect, and COP with variations in compressor rotational speed of 1000 rpm, 1500 rpm, and 2000 rpm. The results showed that the compression work, refrigeration effect, and coefficient of performance (COP) of R-290 had a more excellent value. R-290 produces the highest compression work at a 2000 rpm compressor speed of 33.34 kJ/kg for the refrigeration effect at 1000 rpm of 353.33 kJ/kg and COP at 1500 rpm 12.32.

The Effect of Standard Compression Adjuvant with a Tailored Exercise Training Program on Health-Related Quality of Life Outcomes in Treating Adults with Venous Leg Ulcer: A Randomized Controlled Trial.

Exercise training adjuvant to standard compression is considered to improve calf muscle pump dysfunction in venous leg ulcer (VLU) and subsequent healing. The objectives of this trial were to assess the effectiveness of a tailored exercise training intervention in addition to standard compression therapy on health-related quality of life and anticipating wound healing. Twenty-four VLU participants were recruited and randomly divided into 2 groups. The control group was prescribed conventional compression, and the intervention group received compression plus progressive tailored exercise training. The 14-item chronic venous disease quality of life questionnaire (CIVIQ-14) was used to assess improvement after treatment over time (0, 6, and 12 weeks). Intervention and control groups achieved wound closure for 11 (92%) and 7 (58%) patients. After adjusting for age, sex, and wound size at baseline, the exercise intervention group had 2 times the probability of complete wound healing in 12 weeks than those in the control group (risk ratio = 1.98, 95% CI= 1.01-3.72, P = .047). The primary outcome was the difference in CIVIQ-14 score in 3 dimensions and global index score per visit. The outcomes were evaluated by independent assessors. Demographic, comorbidities, and wound assessments were collected on enrollment. The overall adherence to exercise protocol was 71%. After adjusting age, sex, size of VLU, and CIVIQ score at baseline, the participants in the intervention group had the average global index scores and psychological scores increase at week 12 than those in the control group (21.2; 95% CI= 7.1-35.2, P = .005, and 13.5; 95% CI = 2.9-24.2, P = .044, respectively). Both groups showed similar improvement in the mean change in physical and pain scores within-group over time. Patients with combined conventional compression therapy with exercise training appeared to have a higher quality of life score in psychological and global scores than those with compression therapy alone.

Impact on Health-Related quality of life after wearing compression garment or not for six months in women with mild breast cancer-related arm lymphedema. A cross-sectional study

Background Women with mild breast cancer-related arm lymphedema (BCRAL) mostly receive treatment with compression garments and instructions in self-care to prevent the progression of lymphedema. However, wearing a compression garment may be experienced as negative and may affect health-related quality of life (HRQOL) more than the lymphedema itself. The aim of this study was to investigate if there is a difference in lymphedema-specific HRQOL, between women with mild BCRAL wearing compression garments or not for 6 months. Material and methods Participants with mild BCRAL (Lymphedema relative volume <10%) rated their HRQOL by the Lymphedema Quality of Life Inventory (LyQLI), 6 months after diagnosis and being randomized to compression group (CG) or non-compression group (NCG). Both groups received self-care instructions, and the CG was treated with a standard compression garment, compression class 1. Data from 51 women (30 in the CG and 21 in the NCG), were analyzed. Results Both the CG and the NCG experienced a low negative impact on HRQOL in physical, psychosocial, and practical domains (score <1). However, the CG experienced a higher negative impact on median HRQOL in the practical domain compared to the NCG, 0.23/0.08 respectively, (p = 0.026). In the specific items, more participants in the CG reported a negative impact on HRQOL compared to the NCG in employment activities 23%/0%, (p = 0.032), embarrassment by lymphedema/compression garments 33%/5%, (p = 0.017), feeling discomfort/embarrassment while doing sports and hobbies 30%/5%, (p = 0.034) and having to answer questions about the lymphedema 27%/0% (p = 0.015). Conclusion Overall, the lymphedema-specific HRQOL was high after 6 months in women with mild lymphedema, with only a minor difference between the groups. Some women may however perceive practical and emotional issues with the compression garment. These aspects should be considered in patient education and when planning/evaluating treatment. Trial registration: ISRCTN51918431

Maintaining sleep while improving overnight mobility and comfort with a novel lower limb external mechanical compression system

BackgroundVenous thromboembolism is prevalent, associated with a high degree of morbidity and mortality, and largely preventable. External mechanical compression is a standard of care for prevention, but compliance with traditional external mechanical compression devices is low due to patient reported issues with comfort, mobility, usability, noise, and sleep disturbances. The purpose of this study was to compare user-rated comfort, mobility, usability, noise, perceived sleep disturbance, and objective sleep disturbance for a novel external lower limb mechanical compression device as compared to a standard sequential compression device. MethodUsing a 2-day counterbalanced, within-subject repeated-measures design, 16 participants wore two mechanical compression devices, the commonly-used Kendall SCD Express 9525 (SCD) and the novel Recovery Force Movement and Compressions Device (RF-MAC) for 1 night each in their home while sleep was recorded with polysomnography. For each device, participants also completed questionnaires to assess usability, mobility, perceived noise disturbance, and perceived sleep disturbance. ResultsThe novel RF-MAC device was significantly more comfortable and less noisy than the Kendall SCD. There was marginal evidence that participants sleep longer when wearing the RF-MAC compared to the SCD. User-rated usability, perceived sleep disturbance, and other objective sleep disturbance measures did not differ significantly between the two devices. ConclusionPatients and clinicians should consider the impact of external mechanical compression devices on user comfort and sleep to improve patient compliance.

Making of Pressure Springs From Low Carbon Steel St 37 Material as an Alternative to Standard Pressure Springs in Mold Construction Through Solid Carburation Processes

Compression Spring is one of standard components type that are widely used in machinery construction, as well as in mold construction that serves to restore the position of the ejector mould into position. This study aims to find alternative materials for standard compression spring using specimen test of low carbon steel St 37 in the form of a compression spring is made by using coiling process followed to heat treatment processes such as pack carburizing, hardening, quenching and tempering. To ensure the quality process, the tests should be done in the laboratory such us the hardness test, the distribution of hardness, microstructure and deflection of the spring test. The pack carburizing is done at a temperature of 925ºC with a holding time of 2.5 hours, followed by a case hardening process at a temperature of 870ºC with a holding time of 12.5 minute and quenched on medium oil and tempered at a temperature of 350ºC. The results of this research show that the method used to generate the average value of 456.57 HV and have ? – martensite microstructure and also the compression spring deflection average value of 18.625 N/mm on 613.9 N. Those data approaches the compression spring standard value of hardness, microstructure and deflection. Based on the data analysis, low carbon steel St 37 can be used as alternative material for standard compression spring.

Mechanical, Durability, and Microstructure Investigations on High-Strength Concrete Incorporating Nanosilica, Multi-Walled Carbon Nanotubes, and Steel Fibres

In present research, the strength properties, impact resistance, and durability characteristics of high-strength concrete blended with nanosilica (NS) and reinforced with multi-walled carbon nanotubes (MWCNTs) are discussed. The proportion consists of nanosilica added in a constant addition of 1% and MWCNT added in a varied dosage of 0.025%, 0.05%, 0.1%, 0.15%, and 0.2% by weight of the cement. A total of 11 mixes were made including the control mix having no MWCNT. The other 10 mixes were categorized into two classes with one class having steel fibres incorporated as 1% of the total volume of the concrete along with the other ingredients such as 1% NS and different proportions of MWCNT. The other class was made without steel fibres retaining only the NS and different MWCNT proportions. Besides the standard compression and tension tests, to determine the energy absorbing capacity of the mix specimens, impact test was also performed. The strength tests were carried out for 3, 7, and 28-day curing. Also, durability tests were carried out with sorptivity, porosity, and mass loss of the specimens when exposed to aggressive HCL and H2SO4 acid. To validate the experiment results, microstructure studies such as scanning electron microscopy (SEM) were also conducted on the samples. Among all mixes, 28-day compressive strength (CS) of 0.2% MWCNT with 1% NS and 1% steel fibre mix was found to increase by 22% compared to control concrete.

HYBRID SCHEMES BASED ON WAVELET TRANSFORM AND CONVOLUTIONAL AUTO-ENCODER FOR IMAGE COMPRESSION

In recent years, image compression techniques have received a lot of attention from researchers as the number of images at hand keep growing. Digital Wavelet Transform is one of them that has been utilized in a wide range of applications and has shown its efficiency in image compression field. Moreover, used with other various approaches, this compression technique has proven its ability to compress images at high compression ratios while maintaining good visual image quality. Indeed, works presented in this paper deal with mixture between Deep Learning algorithms and Wavelets Transformation approach that we implement in different color spaces. In fact, we investigate RGB and Luminance/Chrominance YCbCr color spaces to develop three image compression models based on Convolutional Auto-Encoder (CAE). In order to evaluate the models’ performances, we used 24 raw images taken from Kodak database and applied the approaches on every one of them and compared achieved experimental results with those obtained using standard compression method. We draw this comparison in terms of performance parameters: Structural Similarity Index Metrix SSIM, Peak Signal to Noise Ratio PSNR and Mean Square Error MSE. Reached results indicates that with proposed schemes we gain significate improvement in distortion metrics over traditional image compression method especially SSIM parameter and we managed to reduce MSE values over than 50%. In addition, proposed schemes output images with high visual quality where details and textures are clear and distinguishable.

PDC: a highly compact file format to store protein 3D coordinates.

Recent improvements in computational and experimental techniques for obtaining protein structures have resulted in an explosion of 3D coordinate data. To cope with the ever-increasing sizes of structure databases, this work proposes the Protein Data Compression (PDC) format, which compresses coordinates and temperature factors of full-atomic and Cα-only protein structures. Without loss of precision, PDC results in 69% to 78% smaller file sizes than Protein Data Bank (PDB) and macromolecular Crystallographic Information File (mmCIF) files with standard GZIP compression. It uses ∼60% less space than existing compression algorithms specific to macromolecular structures. PDC optionally performs lossy compression with minimal sacrifice of precision, which allows reduction of file sizes by another 79%. Conversion between PDC, mmCIF and PDB formats is typically achieved within 0.02 s. The compactness and fast reading/writing speed of PDC make it valuable for storage and analysis of large quantity of tertiary structural data. Database URL https://github.com/kad-ecoli/pdc.

Calibrated behaviors assessment in spinal cord compression injury model in rats

Spinal cord injuries (SCI) are often associated with dire consequences resulting in the serious pathological conditions in SCI patients. These consequences have resulted in an increased interest of basic science researchers and healthcare professionals to investigate effective treatment of SCI. Among these initiatives, animal experimentation models emerged as a successful tool to study the SCI in detail. We created a standardized spinal cord compression injury model for this research and tested its effectiveness in examining the behaviors of rodents with SCI. We used 24 mature Sprague Dawley rats, weighing between 250 and 320g. Two sets, A and B, of rats were created. Under general anesthesia, Rat from group A underwent laminectomy and only had the T6–T8 vertebrae of their spinal arch removed. in contrast to the rats in group B underwent laminectomy as well as compression injuries using an aneurysm clip of 70 gm for 60 seconds. All the rats were observed at day 7, 14 and 28 following the experimentation. Using standardised techniques, the sensory-motor abilities were evaluated.