Magnetic Composite Nanoparticles Research Articles

Strategic role of casein coated iron oxide nano-particles for delivering nano nutrients for enhance soil quality and their potential

Nanotechnology has many uses and advantages, and it's being used more and more. In agricultural research, it can help with detecting pollutants, fighting plant diseases, delivering pesticides and fertilizers more precisely, transporting genetic material, protecting soil, and making soil stick together better. Since we're facing issues like lower crop productivity, lack of nutrients, and climate change, nanotechnology offers interesting ways to improve farming. It can help manage plant diseases better, make sure plants get the right nutrients, help them grow well, and release pesticides and nutrients in a controlled way.For plants to grow, they require iron, which is essential to chlorophyll synthesis and other enzymatic and metabolic activities. In the current investigation, casein-coated magnetic carriers were produced to provide nutrients to plants and crops. Iron oxide-loaded casein Nano-carriers with a core–shell nanostructure were found to have agricultural benefits. The composition, shape, and structure of magnetic nanoparticles were identified using FTIR, SEM, Raman, XPS, Zeta potential and PXRD. The prepared particles can be used for regulated and targeted nutrition administration. Iron oxide loaded casein nanoparticles will become increasingly important in creating matrices for the regulated release of bioactive substances.

Emergence of magnetic nanoparticles in photothermal and ferroptotic therapies.

With their distinctive physicochemical features, nanoparticles have gained recognition as effective multifunctional tools for biomedical applications, with designs and compositions tailored for specific uses. Notably, magnetic nanoparticles stand out as first-in-class examples of multiple modalities provided by the iron-based composition. They have long been exploited as contrast agents for magnetic resonance imaging (MRI) or as anti-cancer agents generating therapeutic hyperthermia through high-frequency magnetic field application, known as magnetic hyperthermia (MHT). This review focuses on two more recent applications in oncology using iron-based nanomaterials: photothermal therapy (PTT) and ferroptosis. In PTT, the iron oxide core responds to a near-infrared (NIR) excitation and generates heat in its surrounding area, rivaling the efficiency of plasmonic gold-standard nanoparticles. This opens up the possibility of a dual MHT + PTT approach using a single nanomaterial. Moreover, the iron composition of magnetic nanoparticles can be harnessed as a chemotherapeutic asset. Degradation in the intracellular environment triggers the release of iron ions, which can stimulate the production of reactive oxygen species (ROS) and induce cancer cell death through ferroptosis. Consequently, this review emphasizes these emerging physical and chemical approaches for anti-cancer therapy facilitated by magnetic nanoparticles, combining all-in-one functionalities.

Fe3O4 Coated SiO2 Magnetic Nanoparticles for Enhanced Antibacterial Activity and Electrochemical Sensing

Multifunctional magnetic composite nanoparticles (NPs) with antibiotics have demonstrated symbiotic effects because of their promising antimicrobial properties. The antimicrobial agent reduces side effects and dosage, and increases drug delivery efficiency. In this study, SiO2 coated over Fe3O4 magnetic nanoparticles (MNPs) were prepared by a solvothermal method. The MNPs were characterized by using X-ray diffraction (XRD), transmission electron microscopy (TEM), ultraviolet-visible spectroscopy (UV-vis), and Fourier transform infrared spectroscopy (FTIR). The antimicrobial tests were carried out using the disk diffusion method. The electrochemical sensing was investigated by cyclic voltammetry with varying As(III) concentrations from 1–10 ppb. The microstructural results showed the formation of spherical-shaped Fe3O4@SiO2 MNPs with 15–30 nm diameters. UV-vis results showed that Fe3O4 NPs promote visible light absorption of Fe3O4@SiO2 MNPs because of well-structured and unvarying shell thickness which is beneficial for the absorption of organic dyes. With an increase in the concentration of As(III), there was a shift in potential and an increase in oxidation peak current, showing the electrocatalytic capacity of the modified electrode. The SiO2 deposited on Fe3O4 displayed an admirable microbial operation. These Fe3O4@SiO2 MNPs are easily absorbed by cells and have the potential to influence bacterial cells both within and outside of the cell membrane, making them an intriguing candidate for use in a variety of biological applications in the future.

Electric arc synthesis of magnetic Mn-Fe-C nanoparticles

The aim of this research is to investigate the phase transformations and magnetic properties of nanoparticles formed during electric arc sputtering of composite Fe-Mn-C with subsequent annealing of the resulting composite in an oxygen atmosphere. As a result of the study, pure metals, mixed oxides, carbides, and carbon nanocomposites are synthesized. The magnetic susceptibility of Fe-Mn-C composites grows with an annealing temperature increase up to 600°C as compared to the iron-carbon system. The obtained methods and results can serve as a base for new synthesis techniques to obtain composite magnetic nanoparticles with a low carbon content.

Plant mediated magnetic nano composite as promising scavenger's radionuclides for the efficient remediation in aqueous medium

The present investigation demonstrates the environment friendly plant mediated green synthesis of magnetic bio composite nanoparticles by the chemical co-precipitation of magnetite phase from aqueous medium. Water contaminated with uranium is one of the most serious environmental issues. This study aims to overcome this issue by effectively adsorbing uranium from water at a pH range of 7. Several studies have recently been published throughout the world that demonstrates uranium adsorption from water, although they have all been conducted in acidic media with pH less than 6. This work addressed that issue, and maximal adsorption was achieved at pH 7 using a synthetic magnetic bio composites sorbent derived from tree bark (Amla). The magnetic bio composites were characterized by FTIR, XRD, FE-SEM, and EDX. The computations of the XRD data indicated that magnetic bio composites have nano composite with an average diameter of around 12.1 nm. This has an adsorption capacity of 121.95 mg g−1. The correlation regression (r2) coefficients obtained for the various isotherm models indicate that the sorption process conformed to the Langmuir and Temkin models. Thermodynamic studies revealed that the sorption process onto plant mediated magnetic bio material is endothermic and spontaneous, which is significant for reuse and recovery of adsorbed material. A desorption test was also performed to regenerate the material by removing the adsorbed uranium (VI) by HCL with an 84.3% success rate.

The Boundary Between Volume and Surface-Driven Magnetic Properties in Spinel Iron Oxide Nanoparticles

Despite modern preparation techniques offer the opportunity to tailor the composition, size, and shape of magnetic nanoparticles, understanding and hence controlling the magnetic properties of such entities remains a challenging task, due to the complex interplay between the volume-related properties and the phenomena occurring at the particle’s surface. The present work investigates spinel iron oxide nanoparticles as a model system to quantitatively analyze the crossover between the bulk and the surface-dominated magnetic regimes. The magnetic properties of ensembles of nanoparticles with an average size in the range of 5–13 nm are compared. The role of surface anisotropy and the effect of oleic acid, one of the most common and versatile organic coatings, are discussed. The structural and morphological properties are investigated by X-ray diffraction and transmission electron microscopy. The size dependence of the surface contribution to the effective particle anisotropy and the magnetic structure are analyzed by magnetization measurements and in-field Mössbauer spectrometry. The structural data combined with magnetometry and Mössbauer spectrometry analysis are used to shed light on this complex scenario revealing a crossover between volume and surface-driven properties in the range of 5–7 nm.Graphical

Design of functionalized magnetic silica multi-core composite nanoparticles for synergistic magnetic hyperthermia/radiotherapy in cancer cells

Nanomaterials in particular the magnetic nanoparticles (MNPs) offer tremendous potential for cancer treatment due to their unique intrinsic properties. Combining materials with a variety of functional groups, and forming a multifunctional nanosystem to overcome the limitations of monotherapy for cancer treatment has always been a research focus with notable difficulties. Considering the many challenges faced by radiotherapy and hyperthermia, in this study, we designed a rational strategy for magnetic hyperthermia using Fe3O4@SiO2@Sec2@FA nanoparticles as a novel nano-radiosensitizer to simultaneously enhance the therapeutic effects of radiotherapy in the future. Fe3O4@SiO2 core–shell structured nanoparticles were synthesized with an appropriate silica layer thickness to maintain good saturation magnetization. The as-prepared Fe3O4@SiO2@Sec2@FA nanoparticles had the specific absorption rate (SAR)value of 57 W/g, which was below the clinically acceptable alternating magnetic field value of 4.9 × 109 Am−1s−1, indicating good heat generation efficiency (the temperature level ΔT=6–10 °C). Moreover, Folate-modified nanoparticles exhibited approximately 6-fold higher cellular internalization of Hela cells with no obvious cytotoxicity for the Hela and MDA-MB-231 cells, and lower cytotoxicity for the HUVECs in a concentration range of 0–150 µg/mL. In addition, these nanoparticles were modified on the silica surface by L-selenocystine, which could enhance the elimination of tumor cells by producing reactive oxygen species under X-rays, resulting in a novel radiosensitization effect. Therefore, the as-prepared Fe3O4@SiO2@Sec2@FA nanoparticles with good biocompatibility and active targeting would possess synergistic magnetic hyperthermia/radiotherapy effect.

Magnetically recoverable poly (methyl methacrylate-acrylic acid)/iron oxide magnetic composites nanomaterials with hydrophilic wettability for efficient oil-water separation

Due to the environmental and production problems of emulsion, it is important to efficiently separate oil-water emulsion to meet the refinery requirement and clean up oil spills. Synthesis of a universal demulsifier is not an easy task because the physical properties of crude oil vary, which makes its characterization and demulsification procedure difficult. To overcome this problem, hydrophilic and magnetically recoverable poly (methyl methacrylate-acrylic acid)/iron oxide magnetic composite nanoparticles ((P(MMA-AA)/Fe3O4 NPs) were developed as an efficient and economical demulsifier via soap-free emulsion polymerization. To characterize the magnetic composite NPs for their appropriate surface morphology and magnetic domain, TEM, FTIR, VSM, and TGA analyses were carried out. The newly synthesized NPs displayed good hydrophilic properties as they migrated quickly to the aqueous emulsion phase, which was also reassured by their water contact angle of 75°. They exhibit strong magnetic characteristics (20 amu/g) in the oil-water emulsion, makings the hydrophilic wettability capable and attractive to the external magnet. Experimental results revealed that the prepared magnetic composite NPs separated 99% of the water from stable emulsion in 30 min and could be recycled 8 times through magnetic separation. The recycled magnetic composite NPs maintain their hydrophilic wettability and efficiency in separating oil-water emulsion, making them economical and commercially viable. The migration of magnetic composite NPs to the aqueous phase in the stable emulsion with a strong magnetic domain explains the coalescence of emulsified water droplets and their quick separation from the stable emulsions through the external magnet.

Indigenous Sand Drawings as Predictors of the Cell Response to Nanoparticle Therapy

A technique for predicting the response of cells and tissues to a physicochemical stimulus without the use of expensive molecular markers and at time points before any morphological changes can be visibly spotted would be a meaningful addendum to the current set of bioimaging tools. One such method was developed here based on correlating transformed distance matrices of populations of cultured cells and digital checkerboard patterns derived from traditional central African drawings in the sand. Similarity measurements were made at an early time point in the therapy administered to bone cancer cells in the form of composite magnetic nanoparticles. At this early of a time point, the cell viability was mildly reduced, but no gross alterations to the cell morphology or density were visible yet. Similarity score evaluation demonstrated a significantly higher degree of similarity between the patterns derived from the sand drawings and the cells subjected to the treatment than between the former patterns and the untreated cell controls. The treated cells produced more ordered and symmetric patterns than the control ones after the processing of their pairwise distant matrices, explaining their better geometric correlation with the ancestral sand arabesques, which were monolinear and commonly comprised multiple mirror planes and rotational symmetry axes. This has suggested that the course of the therapy could be predicted by a relatively simple comparison between raw optical images of cells and indigenous ideographs using the metrics postulated here. The interdisciplinary method developed in this study may prove applicable for in situ monitoring of the response of cells and tissues to various therapies, allowing for the early indications of adverse effects to be noticed based on the simple optical observations of cells and acted upon before the progression toward nonviable states becomes irreversible. The method elaborated here may also provide an impetus for a broader search for solutions to problems plaguing the modern medicine outside of the scope of its mainstream analytical frameworks and in the ancestral heritage of relatively obscure ethnic traditions.

Buoyant oleophilic magnetic activated carbon nanoparticles for oil spill cleanup

In response to oil spills, it is imperative to develop efficient and eco-friendly sorbent materials. Oil remediation techniques are limited, prompting researchers to look into using nanotechnology for oil cleanup. Therefore, magnetic Fe3O4 composite nanoparticles (MNPs) were synthesized by the chemical co-precipitation method. The MNPs were then coated with activated carbon (AC) layer, followed by soybean oil/stearic acid surface decoration. The morphology and surface properties of the material were characterized using a scanning electron microscope (SEM), Brunauer-Emmett-Teller (BET), and contact angle (CA) analyses. The results showed an excellent amphiphilicity with water CA of 0° and oil CA of nearly 0°. In terms of applicability for oil recovery operations, the fabricated nanocomposite revealed sorption capacities greater than 6.5 g/g for a range of oils. In addition, the sorbent can be reused at least five times with advantageous characteristics for selective oil recovery on surface waters owning to its intense super-paramagnetic properties. Considering our results, we suggest that there is a practical application for magnetic AC nanomaterials in spilled oil response.

Quercetin loading on mesoporous magnetic MnFe2O4@ hydroxyapatite core-shell nanoparticles for treating cancer cells

Despite the availability of various nanostructure for cancer cells therapeutic, caring hydrophobic drugs to the target site is still one of the great challenges in chemotherapy. In this study, quercetin (QC), a poorly water-soluble natural anticancer agent, was used as a model drug to evaluate the efficiency of mesoporous magnetic MnFe2O4 core-shell nanocomposite particles. A simple co-precipitation method was employed to synthesis MnFe2O4 as core of nanostructure. Then, the obtained MnFe2O4 nanoparticles were coated with mesoporous hydroxyapatite (HA) shell as a new perspective for drug loading. The magnetic mesoporous nanostructure had specific surface area and mean pore size of 165.44 m2/g and 11.561 nm, respectively. In QC loading process, the MnFe2O4@HA nanostructure demonstrated loading capacity of 123 µg/mg with pH-depended release manner. In compare with free QC, loaded QC on MnFe2O4 core-shell nanocomposite particles exhibited 55% higher antioxidant activities against free 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals. Moreover, comparative in-vitro anticancer studies on Michigan cancer foundation (MCF)-7 cells, breast cancer cell line, demonstrated more reduction in number of viable cells (35.6%) using loaded QC than that of free QC (50.76%), suggesting improvement in the solubility of QC by loading onto mesoporous magnetic nanocomposite particles compared to free QC.

Optimization of Zn–Mn ferrite nanoparticles for low frequency hyperthermia: Exploiting the potential of superquadratic field dependence of magnetothermal response

Magnetothermal applications of nanoparticles in biomedicine are currently limited by low thermal responses to oscillating magnetic fields on one side and by detrimental physiological effects of electromagnetic radiation on the other side. In this paper, using Zn–Mn ferrite nanoparticles, we demonstrate that an appropriate choice of size and chemical composition of magnetic nanoparticles results in the superquadratic (upto 5th power) dependence of the Specific Absorption Rate (SAR) on a magnetic field (SAR proportional to H5). This gives an opportunity to obtain SAR values above 10 W/g in an oscillating magnetic field, while maintaining the field-frequency product at a level close to the physiological Brezovich's limit ∼ 109A/(m s).

Bimagnetic hard/soft and soft/hard ferrite nanocomposites: Structural, magnetic and hyperthermia properties

Recent studies show that the chemical composition and shape of magnetic nanoparticles (NPs) play an important role in their properties. In particular, the bimagnetic NPs display useful and in many cases, more interesting properties than single-phase NPs. In this work, we prepared Fe 3 O 4 and CoFe 2 O 4 cube-like NPs and bimagnetic hard/soft (CoFe 2 O 4 /Fe 3 O 4 ) and soft/hard (Fe 3 O 4 /CoFe 2 O 4 ) nanocomposites (core/coating) using a facile and eco-friendly co-precipitation method that allows the synthesis of the cube-like NPs at temperatures near room temperature. The phase purity and the crystallinity of the NPs with a spinel structure were confirmed by the X-ray diffraction and infrared spectra techniques. Transmission electron microscopy (TEM) images revealed that the NPs have a cubic-like shape with an average dimension of 20 nm. Energy dispersive X-ray analysis, Mössbauer spectroscopy and SQUID magnetic measurements indicated the co-existence of Fe 3 O 4 and CoFe 2 O 4 phases in nanocomposites. In addition, the hysteresis loops exhibited a single-phase behavior in the nanocomposites that indicates there is a good exchange-coupling interaction between the hard and soft magnetic phases. The CoFe 2 O 4 /Fe 3 O 4 nanocomposites presented a larger saturation magnetization than the CoFe 2 O 4 NPs that is effective for their use in magnetic hyperthermia. Finally, we studied the hyperthermia properties of samples in an alternating magnetic field with a frequency of 276 kHz and field amplitude of 13.9 kA/m. Our results showed that magnetic hyperthermia efficiency simultaneously depends on the composition of samples along with magnetic anisotropy and saturation magnetization.

Optimization of sonication-assisted synthesis of magnetic Moringa oleifera as an efficient coagulant for palm oil wastewater treatment

Optimization of the sonication-assisted synthesis of magnetic Moringa oleifera (MMO) was carried out, to produce an efficient coagulant for palm oil mill effluent treatment. Response surface methodology (RSM) was used to analyse the effect of magnetic nanoparticles (MNPs) composition, sonication time and sonication temperature on coagulation performances to remove total suspended solid (TSS), colour, chemical oxygen demand (COD) and sludge volume index (SVI)). The RSM analyses indicate 1.0 wt% of MNPs, 2.35 min and 50 °C as the optimal MNPs mass fraction, sonication time and sonication temperature, respectively in order to fabricate an efficient MMO coagulant. The analysis of variance (ANOVA), indicate that mass fraction of MNPs and sonication temperature are the most significant parameters. From the statistical analysis, the sonication time did not exert any influence on the fabrication of MMO as well as its coagulation performance. At the optimum conditions, 83.3%, 28.1%, 85.2% removal of TSS, colour, COD as well as 485 mL/g of SVI were respectively achieved. This paper also present the characterization studies on the synthesized MMO using Fourier transform infrared spectroscopy, X-ray diffractometry, scanning electron microscopy and vibrating sample magnetometer analysis. • Magnetic Moringa Oleifera (MMO) coagulant was synthesized via ultrasonic-assisted technique. • Optimization study on synthesis conditions was carried out by response surface methodology. • Magnetic composition and sonication temperature were the significant synthesis factors. • The developed MMO coagulant exhibited ferromagnetic properties.

Impact of the agarose ferrogel fine structure on magnetic heating efficiency

Magnetic nanoparticles-mediated hyperthermia was widely studied in the last decades as applicable in cancer therapy. The majority of magnetic hyperthermia research was devoted to improvement of heating efficiency by application of various nanomaterials. The influence of biocompatibility, magnetic properties, sizes, composition, and concentration of magnetic nanoparticles (MNPs) on hyperthermia efficiency was extensively studied. Also, the limits preserving biological safety and the chemical stability of MNPs delivered to the tissue were established. However, much less research concerned the impact of the physical interactions between the closest MNPs on the hyperthermia efficiency. Our goal was to demonstrate the relationships between the internal structure of soft tissue containing MNPs, and the thermal effects of an alternating magnetic field. Because agarose-based gel exhibits a tissue-like internal structure, we performed hyperthermia experiments in two types of such gel containing bare and polyethylene glycol-coated Fe3O4 nanoparticles. We described the structural difference and we estimated the ferrogels specific absorption rate coefficients (SAR) from calorimetric experiments. Magnetic measurements showed 11% lower magnetic saturation of PEG-coated MNPs than of the bare MNPs. While the SAR of ferrogel with PEG-coated MNPs was 15% greater than bare MNPs. The structural characteristics calculated from TEM and SEM images were significantly different. Particularly, we observed the nanoparticle agglomeration in the gel with bare MNPs. The bare MNPs uniformly packed and located inside agarose double helices were observed for the first time. The distribution of MNPs and their spatial configuration in gel influenced strongly the strength of bonds blocking the movement of MNPs and determined the ferrogels heating efficiency. As the tissues to which we delivered MNPs were composed of agarose gel-like structures, our results may be useful in further research on hyperthermia in vivo.

Preparation of immobilized lipase on Co2+-chelated carboxymethyl cellulose based MnFe2O4 magnetic nanocomposite particles

Lipase immobilization was performed via physical adsorption on a novel metal-chelating nanostructure consisted of (S)-N-(5-Amino-1-carboxypentyl) iminodiacetic acid (NTA), as a tetra-dentate chelating agent, grafted onto MnFe2O4 nanoparticles coated with carboxymethyl cellulose (CMC) for Co2+-chelated affinity lipase adsorption. The influential immobilization parameters for enzyme adsorption were investigated. The maximum amount of immobilized lipase (8.5 mg/g adsorbent) was obtained at modified conditions with initial enzyme concentration of 2 mg/mL and adsorbent dosage of 1 mg/mL after 90 min incubation at 50 mM buffer citrate at pH 5. The Fourier transform infrared spectroscopy (FTIR), energy dispersive spectroscopy (EDS), and elemental mapping provided evidence of successful immobilization of lipase. The results of kinetic study revealed that the adsorption of lipase followed pseudo second order kinetic model. Investigation on the enzymatic properties demonstrated that the immobilized lipase possesses remarkable thermal stability at 60 °C for 120 min, as the catalytic activity of immobilized lipase was 75% higher than that of free lipase at the same temperature. Beside, the immobilized lipase still retained 70% of its initial activity after 7 successive recycles, suggesting the new designed Co2+-chelated magnetic nanostructure as a great matrix for the non-covalent enzyme immobilization.

A versatile synthetic route towards gelatin-silica hybrids and magnetic composite colloidal nanoparticles

A versatile synthetic route towards gelatin-silica hybrids and magnetic composite colloidal nanoparticles

Graphene oxide wrapped magnetic nanoparticle composites induced by SiO2 coating with excellent regenerability

Graphene oxide wrapped magnetic nanoparticle composites induced by SiO2 coating with excellent regenerability

Superparamagnetic Ag-Fe3O4 composites nanoparticles for magnetic fluid hyperthermia

The increased use of superparamagnetic nanoparticles in medical applications motivates the development of new nanostructured materials and nanocomposites with tailored properties. In magnetic fluid hyperthermia, iron oxide nanoparticles destroy or weaken malignant tumor cells by increasing their temperature above a critical value. Therefore, magnetic nanoparticles with high heating efficiency are required. In this work, Ag-Fe3O4 composite nanoparticles and their corresponding ferrofluids are explored for hyperthermia applications. The iron oxide nanoparticles were first synthesized in an egg-white medium via coprecipitation and hydrothermal methods and then decorated with Ag, using honey as a reducing agent. The obtained nanoparticles were fully characterized and used to prepare water-based ferrofluids. The ferrofluid specific loss power was evaluated in an alternating magnetic field with frequency of 274 kHz and amplitude of 13.9 kA/m, confirming that Ag-Fe3O4 composite magnetic nanoparticles have a high potential for heat generation when compared with Fe3O4 nanoparticles. The observed physical properties and heating power values are discussed based on the synthesis route, particle size distribution, and physical properties.

Magnetic and Plasmonic Composite Nanostructures for Creating Optical Filters at Substance and Material Diagnostics Systems

Introduction. Porous silicon (PS) and materials on its basis are of interest for application in nanoelectronics, targeted drug delivery and advanced gas sensors. In addition, PS-based nanostructures are promising as filters in fibre-optic communication systems, since conventional thin-film deposition filters possess sidebands in their operating range thus requiring high vacuum for nanometer-thick coatings.Aim. To develop optical band-stop filter prototypes based on composite magnetic nanoparticles and the effect of localized surface plasmon resonance (LSPR) in an array of silver nanoparticles located on the PS surface. Materials and methods. The development and synthesis of nanostructures for the creation of filter prototypes. The double differentiation method in conjunction with Mie absorption theory was used for processing and analyzing the prototypes attenuation characteristics.Results. Two prototypes were developed. An analysis of the attenuation characteristics of a prototype based on SiO2 matrix functionalized by FemOn indicated that the parameters of the detected absorption bands depend on the size of FemOn nanoparticles. The attenuation characteristics of the LSPR-based prototype contain two absorption bands. The center wavelength value in the band caused by LSPR in the array of silver nanoparticles, close to spherical, is 367.5 nm. Excitation of LSPR in silver quantum clusters, manifested by the appearance of the corresponding band, occurs at a wavelength of 265.5 nm. The suppression in each of the bands can be controlled by changing the parameters of the PS matrix synthesis.Conclusion. Despite the disadvantages, e.g. a relatively low accuracy in setting the center wavelength, as well as certain difficulties concerned with reducing the unevenness in the absorption band, the obtained prototypes surpass existing analogues and are prospective for the development of compact analysis and diagnostics systems in a wide energy range.