For steel-concrete composite bridges, different seismic excitations are selected, and nonlinear time-history analysis method is used to study the influence of near-field seismic impulse effect on seismic response of steel-concrete plate composite beam bridges. The results show that the seismic response of the bridge under impulsive ground motion is obviously greater than that under non-impulsive ground motion, which is very disadvantageous to the seismic resistance of the pier. Under near-field impulsive ground motion, the seismic response of main girder, support and pier is obviously greater than that of non-impulsive ground motion. The displacement of the main girder is magnified by 4.5 times, the bearing response is magnified by 4 times, and the shear force and bending moment of the most disadvantageous section of the pier are magnified by 2.3 times and 4.04 times.