Providing access to quality education is one of the Sustainable Development Goals (SDGs) set by the United Nations to be achieved by 2030 (Goal №4: Quality Education – “Ensure inclusive and equitable quality education and promote lifelong learning opportunities for all”). The unique aspect of higher medical education is that its quality also supports the fulfillment of another SDG (Goal №3: Good Health and Well-being). Higher medical education is dynamic, with a growing global trend toward increasing the emphasis on scientific knowledge within educational programs. In leading countries, courses are being developed that actively incorporate the study of research methods in medicine. The introduction of new educational components aimed at developing scientific competencies in medical students represents a promising approach to improving the quality of education. The aim of this study was to analyze and characterize the structure of the second module in the course “Individual Scientific Work” within the educational and professional program “Medicine”. In preparing the manuscript, the authors employed the following general scientific theoretical research methods: analysis, synthesis, concept comparison, abstraction, and generalization. The primary goal of studying Module №2, “Methods of Researching Pathological Changes in Organs and Systems”, as part of the “Individual Scientific Work” in the educational and professional program “Medicine”, is to develop students’ skills in the methodology of conducting medical research. The thematic plan for Module №2 includes the following topics: Methods of registering functional changes in organs and systems; Methods of researching metabolic disorders; Methods of studying the development of oxidative stress in various organs and systems; Study of changes in the production and signaling of gas transmitters, including nitric oxide, hydrogen sulfide, and carbon monoxide. In conclusion, it should be noted that the structure and content of the second module of the course “Individual Scientific Work” in the context of professional program “Medicine”, developed by the Department of Pathophysiology at Poltava State Medical University, align with the requirements of modern higher medical education.