Compliance Of Pregnant Women Research Articles

Determinan Kepatuhan Ibu Hamil dalam Mengkonsumsi Obat selama Kehamilan

The use of drugs during pregnancy aims to improve the health of the mother and fetus. The provision must be adjusted to the needs of the mother and must be under the supervision of health workers. Maternal compliance in taking drugs during pregnancy is influenced by several factors, such as knowledge, attitudes, explanations of how to use drugs from health workers, perceptions and experiences and others. The purpose of the study was to identify the determinants of compliance of pregnant women in consuming drugs during pregnancy. The research sample was 54 respondents who were pregnant women from March to May 2021. The results showed that 29 respondents (53.7%) were obedient in taking drugs during pregnancy, based on the explanation of the majority of health workers, namely 34 people (79.1%), The majority of knowledge is good, namely 35 people (72.9%). Based on the attitude of the majority positive, namely 44 people (68.8%), based on anxiety about drug side effects the majority were 33 people (68.8%), based on the frequency of routine ANC visits (≥4x) namely 32 people (59.2% ). It is hoped that pregnant women can pay attention to the rules and procedures for taking drugs during this pregnancy.

Mother’s Perception of Anemia and Compliance of Iron Tablet Consumption during Pregnancy

Backgound: Anemia cases are still the main problem found in pregnant women in East Nusa Tenggara Province, Indonesia, especially East Sumba Regency. Anemia is very common in pregnant women and iron deficiency is the main cause. Indonesia has a policy to provide iron supplements to pregnant women. Non-compliance of iron (Fe) tablets is one of the important challenge factors in fighting anemia. Objective: The research objective was to determine the relationship between perceptions and compliance of pregnant women on consuming iron tablets. Methods: This study involved 102 women, namely 34 pregnant women, 34 postpartum mothers and 34 breastfeeding mothers. After obtaining approval from the research ethics commission, data were collected by personal interview. Data were analyzed using the Spearman correlation statistical test. Results: A good perception of 77.5%, moderate 18.6% and less, 5.9%. It was found that the compliance of taking iron tablets was in the good category of 2.9%, sufficient 27.5% and less 69.6%. The results of the Spearman correlation test show a correlation coefficient of 0.164 and a significant 0.100 which means that there is a weak correlation and there is no relationship between perception and compliance of taking iron tablets. Conclusion: The perception of pregnant women about iron is mostly good and the compliance of pregnant women's in taking iron tablets is mostly sufficient. There was no relationship between perception and compliance of taking iron tablets in pregnant women.

Sosialisasi Penggunaan Aplikasi (Sumiferos) Pencegahan Anemia dengan Kepatuhan Ibu Hamil Mengkonsumsi Tablet Besi

The high incidence of anemia in pregnant women is necessary to supervise pregnant women in order to consume Fe tablets regularly. Because in this way, it can ensure the compliance of pregnant women to consume Fe tablets according to the predetermined dose and schedule (Ministry of Health, Republic of Indonesia, 2017). By developing a website-based application model that can be used as communication advice anytime and anywhere to monitor pregnant women to consume Fe tablets regularly. The purpose of this activity is to improve understanding of the use of the Sumiferos application. This community service activity uses the extension method with lectures, demonstrations, and question and answer methods. The results obtained from this activity are that pregnant women can use the Sumiferos application properly. The results of this community service are very important because the officers will monitor them through the Sumiferos application. The conclusion of this community service is that pregnant women are able to use the Sumiferos application properly and the compliance of pregnant women in consuming iron tanlets has increased

Organoleptic Quality Formulation of Soybean Sprouts Milk (Glycine max) and Jawawut (Setaria italica) as a Pregnant Women’s Supplementary Feeding Drink

ABSTRACT Background: Riskesdas data in 2018, the prevalence of pregnant women KEK in Indonesia is 17.3%. Meanwhile, the prevalence of anemia pregnant women in Indonesia has increased compared to 2013, which was 37.1% and in 2018 it was 48.9%. Efforts to overcome the impact of malnutrition in pregnant women can be through interventions by supplementary feeding to pregnant women. Supplementary feeding is already included in the intervention program that has been established by the Indonesian Ministry of Health for pregnant women KEK in the form of biscuits. Based on the evaluation of the Ministry of Health 2017, the implementation of the supplementary feeding has experienced problems with the compliance of pregnant women with supplementary feeding consumption, namely that most pregnant women cannot finish all the supplementary feeding biscuits received. For this reason, an alternative supplementary feeding is used to overcome this problem in the form of vegetable milk drinks from soybean sprouts and millet seeds which are local food ingredients. Objective: This study aims to analyze the effect of millet formulation on soybean sprouts milk as PMT for pregnant women on the organoleptic quality of color, flavour, and taste . Methods: This study used a completely randomized design (CRD) consisting of 4 levels of treatment, namely P1 (100: 0), P2 (60:40), P3 (50:50), P4 (40:60) observations were made on the organoleptic quality of the color, flavour, and taste. Results: The results showed that the organoleptic quality (color, flavour, taste) - on average, respondents like it. Kruskal Wallis statistical test showed a significant effect on color, flavour and taste . The best treatment was P2 (60:40) and the fulfillment of RDA for pregnant women in the first trimester was 87.8% energy, 121.6% protein, 97.9% carbohydrates, 66.4% fat and 49.2% iron.

Level of education, knowledge of pregnant women regarding iron tablets to compliance with their consumption.

Anemia during pregnancy is one of the problems that can increase maternal and infant morbidity and mortality. The need for iron during pregnancy through daily food is still very little. In this case, the government prevents iron deficiency during pregnancy by providing free iron supplements to all pregnant women, but the benefits of giving iron tablets during pregnancy are often hampered by the compliance of pregnant women in consuming iron tablets. Compliance is a behavior that can be influenced by factors from within the individual, namely education and knowledge. This study aims to determine the relationship between the level of education and knowledge of pregnant women with iron tablets with adherence to consuming iron tablets in the working area of ??Menganti Public Health Center Gresik. The design used in this study was cross sectional and included 60 pregnant women who consumed >90% iron tablets given by the government. The data analysis used was univariate analysis and multivariate analysis using binary logistic regression test, which showed that the level of education and knowledge about iron tablets pregnant women had a significant relationship with adherence to consuming iron tablets (<0.05).

Pandemic Impact of Covid 19 on Compliance of Mother for Pregnancy Reviews

Maternal and neonatal services have not escaped the impact of the Covid 19 pandemic. It can indirectly increase the return of mortality and morbidity to both mother and baby. This study aims to assess the impact of the Covid 19 pandemic on the compliance of pregnant women to revisit antenatal care. The sampling technique used in this study was stratified random sampling, using the Lemeshow formula with a sample count of 126 people with the inclusion criteria set by the researcher. The design of this study was analytic observational. Data collection was carried out through observation questionnaire sheets that were collected offline and online (Google Form). The test used in this study was Mann Whitney. The results of the analysis show that the significance value is 0.003 at the 2nd-trimester pregnancy visit and 0.001 at the 3rd-trimester pregnancy visit, therefore, statistically p <0.05 there is a relationship between the impact of the pandemic and the 2nd and 3rd-trimester pregnancy visits. Mann Whitney with a higher ranking ratio (mean) between the affected groups (66.92) and those not affected (41.59). Thus, s who were affected by the pandemic were economically more likely to not attend pregnancy visits compared to those who were not economically affected by the pandemic. The results of the study show that there is a relationship between the impact of the COVID-19 pandemic and the unity of mothers carrying out pregnancy visits during the pandemic, this is due to government policies to limit and also anxiety of pregnant women.

Attitude, Practices, and Compliance on Prenatal Visit Among Pregnant Women In Rural Health Center

This study aimed to determine the attitude, practices, and compliance of pregnant women on a prenatal visit among rural health centers. The study used the descriptive-correlational research design and gathered data using a quantitative approach through a survey questionnaire. Descriptive statistics, Pearson r moment correlation coefficient analysis, and regression analysis used to organize study results. It was found that pregnant women were pregnant at age 25 years old and below, more than half of them were married, and almost half are single mothers. One-third of the participants have earned a college degree, are permanent/regular employees, with a monthly income of Php 10,000 and below. Almost all of them are Phil-health members. Pregnant women have high regard to prenatal care, highly practiced and observed monitoring and compliance of essential prenatal care during prenatal visits. In the end, pregnant women fully complied with the essential prenatal care services. The better the practices of women received during the prenatal visit, the better is their level of compliance with prenatal visits. Therefore, pregnant women are compliant with prenatal visits, and the increasing number of their pregnancies also created a positive attitude and their high practices for prenatal visits. Keywords: Pregnant women, attitude, practices, compliance, a prenatal visit

Sulfadiazine plasma concentrations in women with pregnancy-acquired compared to ocular toxoplasmosis under pyrimethamine and sulfadiazine therapy: a case\u2013control study

BackgroundDosing recommendations for the treatment of pregnancy-acquired toxoplasmosis are empirical and widely based on experimental data. There are no pharmacological data on pregnant women with acute Toxoplasma gondii infection under treatment with pyrimethamine (PY) and sulfadiazine (SA) and our study intends to tighten this gap.MethodsIn this retrospective case–control study, we included 89 pregnant women with primary Toxoplasma infection (PT) treated with PY (50 mg first dose, then 25 mg/day), SA (50 mg/kg of body weight/day), and folinic acid (10–15 mg per week). These were compared to a group of 17 women with acute ocular toxoplasmosis (OT) treated with an initial PY dose of 75 mg, thereafter 25 mg twice a day but on the same SA and folinic acid regimen. The exact interval between drug intake and blood sampling and co-medication had not been recorded. Plasma levels of PY and SA were determined 14 ± 4 days after treatment initiation using liquid chromatography–mass spectrometry and compared using the Mann–Whitney U test at a p < 0.05 level.ResultsIn 23 PT patients (26%), SA levels were below 20 mg/l. Fifteen of these 23 patients (17% of all patients) in parallel presented with PY levels below 700 µg/l. Both drug concentrations differed remarkably between individuals and groups (PY: PT median 810 µg/l, 95% CI for the median [745; 917] vs. OT 1230 µg/l [780; 1890], p = 0.006; SA: PT 46.2 mg/l [39.9; 54.4] vs. OT 70.4 mg/l [52.4; 89], p = 0.015) despite an identical SA dosing scheme.ConclusionsSA plasma concentrations were found in the median 34% lower in pregnant women with PT compared to OT patients and fell below a lower reference value of 50 mg/l in a substantial portion of PT patients. The interindividual variability of plasma concentrations in combination with systematically lower drug levels and possibly a lower compliance in pregnant women may thus account for a still not yet supportable transmission risk. Systematic drug-level testing in PT under PY/SA treatment deserves to be considered.

PENGARUH KEPATUHAN IBU HAMIL TERHADAP KEBERHASILAN PENANGANAN PREEKLAMPSIA DI RUMAH SAKIT SANTA ELISABETH BATAM TAHUN 2014

Preeclampsia and eclampsia is a pregnancy complication caused directly by pregnancy itself. Successful handling of preeclampsia is determined by the compliance of pregnant women in antenatal care. Pregnant women who do not checkups cause no detection of high risk factors experienced during pregnancy. This is because women do not obey the doctor's orders to carry out checks ANC, diet and adequate rest.This study aims to identify and analyze the effect of maternal adherence (Antenatal Care, diet and rest) to the successful treatment of preeclampsia in Batam Elisabeth Hospital in 2014. The method used is explanatory survey with cross sectional design. The study population is the entire third trimester pregnant women. The research sample that is the entire third trimester pregnant women who checkups at Saint Elisabeth Hospital Batam as many as 47 people. Data were analyzed by multiple logistic regression.The results showed that there was influence compliance in the rest of the successful handling of preeclampsia (p = 0.002), whereas compliance in Antenatal care (p = 0.076) and compliance in the diet (p = 0.631) did not affect the success of treatment of preeclampsia.It is advisable for pregnant women to reduce the routine activities and undertake light activity in an effort to prevent preeclampsia, and it is expected that health professionals, in order to provide counseling for pregnant women who perform health checks, on the benefits of antenatal care, follow the diet and rest in improving maternal health during pregnancy.

The Effect Of Fe Tablet Consumption On Hemoglobin (Hb) Increase In Pregnant Women: A Systematic Literature Review

Anemia is still a problem in developing countries. The World Health Organization states that there are still more than 50 percent of women in the world suffering from anemia. anemia can cause life-threatening bleeding, miscarriage, low birth weight and premature birth. WHO defines anemia as a condition where the hemoglobin level is less than 11 mg / dL in the first and last trimester or 10.5 mg / dL in the second trimester or the hematocrit level is less than 37 percent. The study aim to determine the effect of Fe tablets consumption on hemoglobin (Hb) level increase in pregnant women and to find out the factors related to the compliance of pregnant women taking Fe tablets. This Systematic Literature Publication and Science uses databases with the period 2008-2018. The selection of articles was based on the inclusion and exclusion criteria. The Appraisal study employed The Joanna Briggs Institute Critical Appraisal Tools. Taking Fe tablets is very influential in increasing levels of Hb in pregnant women who suffer from anemia. Effective iron supplements to reduce anemia in pregnancy. Support from family and closest people has an important role in increasing adherence to taking Fe tablets.

Effectiveness of website application (Sumiferos) for preventing anemia with pregnant women compliance in consuming Fe tablets

Background: The consumption of Fe tablets needs to be the attention of midwives as one of the spearheads in providing antenatal care services. Due to the low level of compliance of pregnant women to consume Fe tablets, it is necessary to provide appropriate counseling as an effort to increase compliance with Fe tablets. Objective: This study aimed to determine the effectiveness of the application model (Sumiferos) for preventing anemia with pregnant women compliance in consuming Fe tablets at Putri Ayu Health Center in Jambi city. Materials and methods: This study used a quasi-experimental research design with a post-test design by involving an intervention group and a control group (post-test), two group designs. With the total of 70 subjects;the intervention group, 35 respondents were given a website application (sumiferos), and a control group 35 respondents were given a leflet. After a month, the number of Fe tablets that have been consumed was monitored. Compliance of pregnant women in consuming Fe tablets required a monitoring or supervisioncarried out by health workers. Therefore, an intervention was given by using a website-based application (sumiferos) for pregnant women as a communication tool that has been created and designed previously by researchers. Results: Posttest statistical analysis showed that pregnant women who were given a website application (sumiferos) in the intervention group showed better compliance than pregnant women in the control group given lefket. Conclusion: Based on the results,a website application (sumiferos) is more effective than leaflets in improving maternal compliance to consume Fe tablets given by health workers.

Smartphone Message to Improve the Drug Compliance in Pregnant Women.

Smartphone Message to Improve the Drug Compliance in Pregnant Women.

Role of pharmacist's counseling on folate compliance

Background: Pregnant women's compliance with a regimen of folate supplementation is an important factor in decreasing incidence of neural tube defects (NTDs). Because effective medication counseling can be used to enhance women's compliance with folate intake, pharmacists can help ensure good pregnancy outcomes by improving women's compliance through such counseling. Objectives: To determine the effect of medication counseling delivered by pharmacists on compliance among pregnant women in Tabuk, Saudi Arabia. Materials and Methods: A cross-sectional analytical study was conducted of 360 pregnant women who attended antenatal care clinics at primary health-care centers in 2018. A well-designed questionnaire was used for data collection. The data were analyzed using descriptive statistics and the Chi-squared test. Results: About half of the study participants began consuming folic acid after becoming pregnant (55.8%) and only 28.6% reported preconceptional intake. The most common reason for noncompliance was forgetfulness (64.40%). Almost two-thirds of women knew the importance of taking folate in pregnancy to prevent NTDs (64.2%). Their main sources of knowledge about folic acid were doctors (35.8%) and pharmacists (25%). A significant association was found between regular folate intake and pharmacist counseling as a source of folate information. Conclusion: Almost half of pregnant women complied with their folate supplementation regimen. However, lower preconceptional intake was observed. Participants' level of awareness of the importance of folic acid supplementation for pregnant women, though adequate, was not sufficient to ensure good pregnancy outcomes. Pharmacists were identified as a valuable source of information about folic acid, with their provision of medication counseling significantly associated with regularity of folate intake.

A compliance of pregnant women to folic acid supplementation in Arkhangelsk Region

A compliance of pregnant women to folic acid supplementation in Arkhangelsk Region

744: Dietary intervention program for women at risk for preeclampsia

Preeclampsia (PE) is a multi-system placental vascular disorder that adversely affects the mother and fetus. In developing countries, 10-20% of maternal mortality is directly related to PE. Low dose aspirin is recommended for PE prevention in high risk women. Calcium supplementation is recommended by the WHO in low intake areas. We conducted an intervention study to evaluate the preventive potential of a complete nutritional program (CNP) for pregnancies with risk factors for PE. A RCT multicenter trial that examined the influence of CNP on women with risk factors for PE, implemented from the 8th gestational week to delivery was conducted during April 2015 - October 2017. Forty-six pregnant women with risk factors for PE were divided to two groups; the intervention group (N=26) received 8 CNP sessions, nutritional supplementation of calcium and vitamin D, and dietary weight control counseling. The control group (N=20) received 5 follow up sessions with no nutritional counseling. The collected data included anthropometric measurements, blood pressure, 24h dietary recall, and neonatal outcomes There was no significant differenced in demographic data between groups at inclusion. For the intervention group calcium, vitamin D and iron consumption were significantly higher during pregnancy (P< 0.05) (Figure 1). Satisfaction from followup was significantly higher in the intervention group. No significant differences between the study groups were observed regarding blood pressure, newborn weight or delivery mode. Two cases of hypertension and one of PE were observed in the control group, compared to none in the intervention group, with no statistical significance due to small group size. Our intervention program showed feasibility, motivation and compliance of pregnant women with risk factors for PE to participate in a nutritional counseling intervention program aimed to improve nutritional status during pregnancy. Further research is needed to investigate the possible clinical influence of targeted nutritional counseling intervention programs on PE incidence and severity.

Brief counseling by pharmacists enhances the knowledge, perceptions, and compliance of first and second-trimester pregnant women consuming ferrous fumarate at Jetis Community Health Center of Yogyakarta

In Indonesia, the prevalence of anemia during pregnancy increased from 37.1% in 2013 to 48.9% in 2018. It plays a significant part in elevated maternal mortality and perinatal rates. This research aimed to determine the influence of a brief counseling intervention by pharmacists based on the ‘5A’ strategy that had been modified to include the knowledge, perceptions, and compliance of pregnant women with the recommended consumption of ferrous fumarate as anemia treatment and prevention. It is a quasi-experimental study with a pretest-posttest control group design. The data were collected prospectively from December 2018 to February 2019. The sample consisted of 26 respondents, divided into a control group and an intervention group. Each group comprised 13 pregnant women in their first and second trimester (ranging from 12 to 27 weeks). The knowledge, perceptions, and compliance in each group were measured on the first day of visit (Day 1; pretest) and Day 31 (posttest) after the intervention. The results showed a significant difference in average scores between the pretest and posttest in the intervention group (p&lt;0.001 for knowledge, perceptions, and compliance parameters) but an insignificant difference in the control group (p=0.185, p=0.366, and p=0.111, respectively). Score difference or improvement was determined from the relative risk (RR) values of the three parameters (4.55, 4.54, and 10.29, respectively, with p&lt;0.50). As a conclusion, a brief counseling intervention based on the modified ‘5A’ strategy can enhance the knowledge, perceptions, and compliance of first and second-trimester pregnant women at Jetis Community Health Center with the proper consumption of Fe fumarate as an iron supplement.

Peran Bidan Dalam Pemberian Suplementasi Tablet Tambah Darah (Ttd) Untuk Pencegahan Anemia Ibu Hamil Di Puskesmas II Kembaran Kabupaten Banyumas

Supplementary iron tablet coverage does not necessarily reflect the success of the program whenviewed from the current high rate of anemia. The low compliance of pregnant women inconsuming iron supplements is one of the causes of the prevalence of anemia is still high. It occursin the working area of ​​ Health Center II Kembaran. Compliance with pregnant women can befurther improved if the midwife is able to provide nutrition counseling, especially about thebenefits of iron tablets and the health of pregnant women. The purpose of this study is to analyzethe extent of the role of midwives in efforts to prevent anemia. The design of this study usesqualitative methods with a case study approach. Determination of informants is done by PurposiveSampling. Data collection is done by in-depth interviews, field observations and document review.The results of this study Midwives have provided health education to pregnant women abouttablets plus blood (TTD or iron tablet) but have not used the media and have given thesesupplements a minimum of 90 tablets but supervision of the compliance of pregnant women hasnot been maximized. So it needs to involve health cadres, families know the closest people topregnant women improve compliance and utilize KIA book mediakeywords:Anemia, the role of midwives

Sequential compression device compliance in pregnant women requiring antepartum admission

Background A quality improvement study done at the Medical College of Wisconsin between 2014 and 2016 demonstrated that, at baseline, sequential compression devices (SCD) were ordered for 46.0% of admitted antepartum women. In response, provider education and a prechecked SCD order in the electronic antepartum admission order set were implemented. Objective To examine the effect of these interventions on SCD compliance during antepartum admissions. Study design This was a prospective observational study of antepartum women admitted for nondelivery indication for more than 24 hours, from June 2017 through March 2018, in a single tertiary center. The study was conducted a year after provider education and implementation of a prechecked order for SCD in the electronic antepartum admission order set. Women with an active venous thromboembolism (VTE) and those already receiving pharmacologic thromboprophylaxis were excluded. The primary outcome was the rate of SCD compliance, assessed both among obstetric providers and patients. SCD compliance for providers was defined as SCD order present in patient’s electronic medical record and documenting the presence of SCD in patient’s room. SCD compliance for patients was defined as documentation that the patient was wearing SCD that were turn on while in bed during morning study rounds. Results During the study period a total of 182 rounding encounters were documented for 76 women. SCD was ordered in 77.6% (59/76) of the admissions. Out of the 59 electronic orders for SCD, 45 orders (h 76.3%) were placed on hospital day 1 (and 42 orders had confirmation of SCD present in the room (71.2%)). SCD were in active use in 45.2% (19/42) of these women. When evaluating the daily course of the hospitalization (n = 182), SCD were ordered in 86.8% (158/182) of the encounters and present in the room in 72.2% (114/158) of the daily encounters. After excluding 10 women who were ambulatory at the time of rounding (n = 104), SCD were observed being used in 31.7% (33/104) of the nonambulatory women encounters with SCD ordered and present in the room. Conclusion A prechecked antepartum order set for SCD increased the rate of provider compliance with SCD. However, this increase did not result in high patient compliance with SCD among antepartum women requiring admission for longer than 24 hours. Condensation A prechecked order for SCD did not lead to high SCD compliance among admitted antepartum women.

Health professionals' experiences and views on obstetric ultrasound in Rwanda: A cross-sectional study.

ObjectivesImplementation of ultrasound in antenatal care (ANC) in low-income countries has been shown to increase pregnant women’s compliance with ANC visits, and facilitate detection of high-risk pregnancies. In Rwanda, as in other low-income countries, access to ultrasound has increased significantly, but lack of training is often a barrier to its use. The aim of this study was to investigate Rwandan health professionals’ experiences and views of obstetric ultrasound in relation to clinical management, resources and skills.MethodsA cross-sectional questionnaire study was undertaken between November 2016 and March 2017, as part of the CROss Country UltraSound Study (CROCUS). Data were collected at 108 health facilities located in both rural and urban areas of Rwanda, including provincial, referral, district and private hospitals as well as health centres. Participants were obstetricians (n = 29), other physicians (n = 222), midwives (n = 269) and nurses (n = 387).ResultsObstetricians/gynecologists/other physicians commonly performed ultrasound examinations but their self-rated skill levels implied insufficient training. Access to ultrasound when needed was reported as common in hospitals, but available to a very limited extent in health centres. The vast majority of participants, independent of health profession, agreed that maternity care would improve if midwives learned to perform basic ultrasound examinations.ConclusionsBarriers to provision of high quality ultrasound services include variable access to ultrasound depending on health facility level and insufficient skills of ultrasound operators. Physicians in general need more training to perform ultrasound examinations. Implementation of a general dating ultrasound examination seems to be a relevant goal as most health professionals agree that pregnant woman would benefit from this service. To further improve maternity care services, the possibility of educating midwives to perform ultrasound examinations should be further explored.

Pregnancy-Related Immune Adaptation Promotes the Emergence of Highly Virulent H1N1 Influenza Virus Strains in Allogenically Pregnant Mice

Pregnant women are at high risk for severe influenza disease outcomes, yet insights into the underlying mechanisms are limited. Here, we present models of H1N1 infection in syngenic and allogenic pregnant mice; infection in the latter mirrors the severe course of 2009 pandemic influenza in pregnant women. We found that the anti-viral immune response in the pregnant host was significantly restricted as compared to the non-pregnant host. This included a reduced type I interferon response as well as impaired migration of CD8+ Tcells into the lung. The multi-faceted failure to mount an anti-viral response in allogenic pregnant mice resulted in a less stringent selective environment that promoted the emergence of 2009 H1N1 virus variants that specifically counteract type I interferon response and mediate increased viral pathogenicity. These insights underscore the importance of influenza vaccination compliance in pregnant women and may open novel therapeutic avenues.