IntroductionFracture reduction, implant selection and tuberosity reattachment propose significant challenges in reverse shoulder arthroplasty (RSA) for proximal humerus fractures (PHFs). It is hypothesised that preoperative virtual surgical planning (VSP) can improve implant positioning and tuberosity reattachment, resulting in better functional outcomes, reduced surgery time, and decreased complication risk. Therefore, this study aims to develop, implement, and evaluate a VSP protocol for RSA in complex PHFs. MethodsThe VSP protocol is developed using 3D medical image processing software based on CT scans from four previously treated patients with RSA for complex PHF. Next, the VSP was applied prospectively in a patient with a PHF planned for RSA. Evaluation was done using an expert opinion questionnaire evaluating surgical confidence, a comparison between implant positioning on postoperative radiographs and the VSP, functional outcomes and the Oxford Shoulder Score (OSS). ResultsThe study showed that VSP is a useful preoperative tool to optimize clinical outcome by digital fracture reduction, determination of surgical cuts, calculating implant size and height, and optimising tuberosity shape and reattachment. After two and six months, the patient showed good functional outcomes (OSS: 48/48 points), healing of tuberosities, and had minimal pain complaints. ConclusionVSP for RSA in PHF might create a more thorough preoperative understanding of the fracture pattern and implant and fracture fragment placement. Further investigative study would be required to demonstrate this.