Complex Bridge Research Articles

CARC21: Outcomes in Transplant Recipients Bridged with Impella Support: A GUARDIAN-Heart Subgroup Analysis

Background: The 2018 UNOS allocation changes prioritized recipients bridged with temporary MCS, which has recently increased in use. Also in 2018, the SherpaPak Cardiac Transport System (CTS) was introduced, which maintains donor heart temperatures continuously between 4°C - 8°C, potentially minimizing freezing-related myocardial injury. A subgroup analysis of the GUARDIAN Heart Registry examined outcomes in transplant recipients bridged using Impella. Methods: The GUARDIAN registry is an international, multicenter registry assessing outcomes after heart transplant comparing CTS preservation and traditional ice-cold (ICE) donor heart storage. Retrospective review of clinical outcomes in recipients bridged with an Impella were examined using summary statistics. Further analysis with ongoing enrollment will be available for presentation. Results: A total of 47 recipients with an Impella device received donor hearts preserved using either CTS (n=33) vs ICE (n=14). The two groups had similar baseline characteristics except the CTS cohort had significantly longer average ischemic time (175.3 vs and 223.9 minutes, p value = 0.02, ICE vs CTS,) and greater procurement distance travelled (170.2 vs 447.5 miles, p value < 0.001, ICE vs CTS). Post-transplant rates of severe PGD were low (14.3% vs 3.0%, p value = 0.15, ICE vs CTS, respectively). Survival was excellent with 100% 30-day survival in both cohorts. Conclusions: Despite significantly longer ischemic times by 48.6 minutes and over 2.5x farther organ procurement distance travelled, the use of the CTS was associated with excellent post-transplant outcomes in patients bridged using an Impella device. Considering ischemic time is a known risk factor for post-transplant PGD, these data support continued study of CTS use to optimize outcomes, in particular in an era of increasing distance travelled for organ procurement and complex bridging strategies.

A Highly Sensitive Luminescent Upconversion Nanosensor for Turn-On Detection of As3.

A luminescent nanoprobe (NP), MnO2-modified Er3+/Yb3+-codoped Ag2MoO4 upconversion nanoparticles (UCNPs; cod-AMO-3/MnO2), was constructed for rapid, sensitive, and selective "turn-on" detection of trace As3+. Herein, two kinds of luminescent NPs were developed based on luminescence resonance energy transfer (LRET) between cod-AMO-3 as the energy donor and MnO2 as the energy acceptor. By using MnO2 as the matrix in cod-AMO-3/MnO2 fluorometric assay, the upconversion luminescence (UCL) intensity (IUCL) of the cod-AMO-3 probe was quenched significantly through LRET, illustrating MnO2 as an efficient quencher for UCL. With the addition of As3+, a stable bidentate binuclear (BB) corner-sharing bridged complex (As5+-MnO2) was probably formed, which alters the surface of the upconversion NP, leading to gradual separation between UCNPs and MnO2 and subsequent recovery of IUCL. Interestingly, it possessed superior sensitivity, reaction kinetics, and also high selectivity toward As3+ in aqueous solution. Our optimized cod-AMO-3/MnO2 nanocomposite (NComp) demonstrated a linear range of 0-150 ppb and an ultrasensitive detection limit of 0.028 ppb for As3+, which is extremely below the regulatory level, signifying the promising practical usage of this system. To the best of our knowledge, such a surface-modified Ln3+-codoped Ag-based nanosensor being applied for As3+ detection probably has not been reported yet, and it is rather unexplored. In a nutshell, the ability to monitor the As3+ concentration may enable the rational design of a convenient platform for a diverse range of environmental monitoring applications.

Betweenness Centrality-Based seismic risk management for bridge transportation networks

Although bridges are integral parts of transportation networks, they are vulnerable to natural hazards. The damage incurred during these natural hazards events leads to network disruptions and hinders post-event recovery. Therefore, improving the seismic performance of transportation networks is critical. This paper proposes an origin–destination pair betweenness centrality (BC)-based methodology to rank bridges according to their importance in a complex bridge network. The proposed methodology is an easy-to-use approach that considers user equilibrium and topology and significantly shorten the computational time. In addition, this study proposes two strategies including the retrofit of bridges and construction of new bridges based on the BC importance of bridges to mitigate the seismic risk of bride networks. A well-studied bridge network in California was used to demonstrate the application and the effect of different strategies was compared in this study. Bridges located at the shortest path significantly affect the seismic performance of bridge networks, indicating there is no need to rehabilitate or replace all bridges under budget constraints. Also, constructing five new bridges based on BC importance improved seismic performance of the bridge network much more than retrofitting 21 bridges. Moreover, the proposed methodology presents a significant reduction in computational time (only 1/30 compared with an existing study) in resolving the importance of bridges in a network and can be applied to provide useful information for disaster management teams to mitigate the seismic risk of bridge networks.

New Method for Fine Calculation of Bridge Temperature Field Based on BIM Solar Radiation Analysis

Fine calculation of bridge temperature fields is significant for accurately evaluating thermal actions in bridge structures. Determining thermal loads on bridge surfaces caused by solar radiation is the most challenging part of the numerical thermal analysis because the sunlit and shaded areas on bridge surfaces change continuously with the sun’s rotation. Existing methods have low accuracy in determining thermal loads and cannot be applied to complex bridges. This study presents a new method for calculating temperature fields based on the advantages of building information modeling (BIM) technology in solar radiation analysis (SRA) and information sharing. This method starts with obtaining an accurate hourly insolation distribution on bridge surfaces through SRA implemented in a BIM system. Then, a Python script seamlessly maps the insolation information to finite element surfaces as thermal loads. This paper details the new method’s implementation steps and technical details, and a practical application on a concrete box girder demonstrates its applicability and effectiveness. Compared with previous methods, the proposed method has significant advantages, such as a more accurate calculation for solar radiation, a lower technical threshold, a higher degree of automation, less computational time, and easier finite element modeling.

Influence of Pile-Cap Elevation and Skewness on Clear Water Scour at Complex Bridge Piers

Influence of Pile-Cap Elevation and Skewness on Clear Water Scour at Complex Bridge Piers

Oxidized Bridged Carbenoids as Viable Intermediates in a Fe(III) Catalyzed C-H Insertion Reaction.

Fe catalyzed carbene insertion reactions present an efficient route for direct C-H functionalization. The use of Fe(III) in place of the widely used Fe(II) presents several benefits. However, the mechanistic understanding of Fe(III) severely lags behind Fe(II) complexes. One of the major unsolved issues relates to the formation of bridged versus terminal metallocarbenes. Even though the oxidized bridged carbenoid complexes have been isolated and found to be thermodynamically more stable, they are generally considered a dead end for the catalytic cycle. In the current report, the formation and the subsequent reactions of the bridged carbenoid complexes for an Fe(TPP)Cl catalyzed C(sp2 )-H insertion are investigated. Using DFT calculations, it is observed that both mono and bis oxidized bridged carbenoid complexes can participate in the catalytic cycle. Importantly, for the first time, a mechanistic pathway showing that these bridged species are not a dead end in Fe catalysis is presented. Their existence in other reactions might be more prevalent than what is currently believed. The current study will have important implications in utilizing Fe(III) complexes for other insertion reactions, especially for heme containing enzymes which necessarily need to be carried out under anaerobic/reducing conditions.

Detrital zircon geochronology of quartzites from the Central Zone of the Limpopo Complex in southern Africa: Implications for different models and the timing of Zimbabwe Craton–Kaapvaal Craton amalgamation

U–Pb geochronological analyses have been conducted on 765 detrital zircon grains from 11 quartzite samples in the Central Zone of the Limpopo Complex, southern Africa, for constraining the depositional age and provenance of the protolith quartz-sandstone and evaluating the effect of high-grade metamorphism on zircon age data in polymetamorphic terranes. The age data have also been used to evaluate two contrasting tectonic models for the evolution of the complex; collision of the Zimbabwe and Kaapvaal Cratons and diapir-driven intracratonic orogeny, both during the Neoarchean. Magmatic cores of the zircons from the Beit Bridge, Phikwe, and Motloutse Complexes in the Central Zone show a wide age range from 3828 Ma to 1995 Ma. Ages from the Beit Bridge Complex in Zimbabwe (ca. 3.6–3.1 Ga) and South Africa (ca. 3.5–2.4 Ga) are dominantly Paleoarchean to Neoarchean with minor Paleoproterozoic ages. Similar Eoarchean to Neoarchean ages were also obtained from the Phikwe Complex (ca. 3.8–2.6 Ga), whereas ages from the Motloutse Complex are slightly younger (early Mesoarchean to Paleoproterozoic; ca. 3.0–2.4 Ga). Although the age patterns from the three complexes are different, the distribution patterns of discordant and concordant data suggest Eoarchean to Mesoarchean (ca. 3.8–3.1 Ga) ages for magmatic cores of detrital zircon grains. Homogeneous zircon rims around magmatic cores gave metamorphic ages of ca. 2.61 Ga and ca. 2.27–2.02 Ga, probably formed by Neoarchean and Paleoproterozoic high-grade metamorphisms. Similar Neoarchean (ca. 2.7–2.6 Ga) and Paleoproterozoic concordant ages obtained from magmatic zircon cores are interpreted as reset ages due to Pb loss during the metamorphic events. The smaller peak of the Paleoproterozoic age population compared to that of the Neoarchean age data suggests the dominant high-grade metamorphism of the Central Zone took place at ca. 2.7–2.6 Ga, either by collision of the Zimbabwe and Kaapvaal Cratons or by diapir-driven intracratonic orogeny. Therefore, cratonization of the Azanian (Kalahari) Craton probably occurred before ca. 2.6 Ga. Based on the age patterns, the depositional age of the protolith quartz-rich sandstone is constrained as 3.1–2.7 Ga. The provenance of the Paleoarchean to Mesoarchean (3.6–3.1 Ga) detrital zircons has been inferred as orthogneisses and granitoids of the southern Zimbabwe Craton (e.g., Tokwe Segment). The oldest Eoarchean detrital zircon (3828 Ma) obtained from the Phikwe Complex suggests the presence of unknown older crust in this provenance.

Investigations of Ratio-Based Integrated Influence Lines as Features for Bridge-Damage Detection

Prestressed concrete bridges built between 1960 and 1990 no longer meet today’s requirements due to loads and increasing mileage of higher loads that have increased since the bridges were designed. Prestressed concrete bridges are representative of Germany’s existing bridges. In order to deal with the large number of ageing bridges, recalculations and measurements for control as well as bridge monitoring are an important means of support. For both, it is important to find features that are damage-sensitive as well as robust against measurement noise, vehicle parameters (dynamics, geometry, weight, etc.) and environmental influences (temperature, wind, etc.). In this paper, we present features for damage detection based on the influence line, which are investigated with respect to the above requirements by using the analytical solution of the Euler–Bernoulli beam and more complex numerical bridge simulations. In this context, we restrict ourselves to the damage caused by bending stress. The features are calculated on the basis of single vehicle crossings over the bridge for the strain in the longitudinal direction as well as for the deflection of the bridge at different sensor positions. The ratio-based features are compared with raw data and natural frequencies in a classification. Additionally, the sensor positioning is considered. The investigations shows that the ratio-based integrated influence lines are equivalent to or better than the modal parameters, especially when noise and temperature changes are taken into account.

Parameters Design of Transverse Seismic Dampers for Complex Bridge Types—an Example of a Double-width Double-tower Cable-stayed Bridge

Large and complex bridges usually have significant nonlinear effects. In the design of seismic and other dynamic characteristics, it is usually impossible to obtain results from simple force calculations. In this paper, taking the mechanical parameters of the complex structure of double wide double tower cable-stayed bridge as an example, a shear damper in seismic field is designed. The experimental results show that: (1) The shear type mild steel damper can improve the lateral seismic performance of cable-stayed bridges. (2) Because the double span cable-stayed bridge is connected by dampers between towers, the mechanical parameters of dampers will affect the natural structure of the bridge, and there is no obvious linear relationship between the yield force of the damper and the bending moment at the bottom of the tower.

Waste-Based Ceramsite for the Efficient Removal of Ciprofloxacin in Aqueous Solutions

Ciprofloxacin (CIP), a compound with bioaccumulation toxicity and antibiotic resistance, is frequently detected in water at alarming concentrations, which is becoming an increasing concern. In this study, a low-cost ceramsite was developed from industrial solid wastes through sintering to remove CIP from wastewater. The effects of adsorbent dosage, initial pH, contact time, initial CIP concentration, and temperature were explored. More than 99% of CIP (20-60 mg/L) was removed at around pH 2-4 by the ceramsite. The kinetic data fitted well with the pseudo-second-order model, revealing that chemisorption was the main rate-determining step. The isotherm data was better described by the Freundlich model, suggesting that CIP was removed by the formation of multiple layers on the heterogeneous surface. Moreover, the removal efficiency was practically higher than 95% during five regeneration cycles, when different regeneration methods were used, including calcination, HCl, and NaOH washing, indicating that the ceramsite exhibited outstanding reusability in removing CIP. The primary mechanism of CIP removal by the ceramsite was found to be the synergism of adsorption and flocculation, both of which depended on the release of Ca2+ from the ceramsite. In addition, strong Ca-CIP complexes could be formed through surface complexation and metal cation bridging between Ca2+ and different functional groups in CIP.

Reliability analysis of complex structures based on Bayesian inference

This paper outlines a logical process based on Bayesian inference to exploit monitoring observations to improve the accuracy in the reliability estimates of civil structures that are retrofitted during their service lives. The proposed approach is particularly effective for complex structures, whose response prediction is affected by structural parameters with significant uncertainty; typical examples are prestressed concrete bridges, heavily influenced by the inherent uncertainties of the material’s creep and shrinkage. The methodology is applied to a real-life complex bridge in Italy, as opposed to academic problems and laboratory tests; the structural model developed for this study includes the original creep law of the Model B3 proposed by Bazant rather than linear approximation or response surfaces. The Bayesian inference is performed using a Markov Chain Monte Carlo (MCMC) method, while the reliability assessment utilises importance sampling (IS) for computational efficiency. The results show the extent to which structural health monitoring (SHM) and Bayesian inference reduce the uncertainty in structural parameters and the prediction of the structural demand. At the same time, they increase structural reliability. Particular attention is given to computational effort, structural modelling and algorithm optimisation.

The Complex Bridge between Aquatic and Terrestrial Life: Skin Changes during Development of Amphibians.

Amphibian skin is a particularly complex organ that is primarily responsible for respiration, osmoregulation, thermoregulation, defense, water absorption, and communication. The skin, as well as many other organs in the amphibian body, has undergone the most extensive rearrangement in the adaptation from water to land. Structural and physiological features of skin in amphibians are presented within this review. We aim to procure extensive and updated information on the evolutionary history of amphibians and their transition from water to land-that is, the changes seen in their skin from the larval stages to adulthood from the points of morphology, physiology, and immunology.

Investigation on Effect of Reflective Coating on Temperature Field of CRTS Ⅱ Slab Ballastless Track under Sunlight

The internal temperature variation of ballastless track is very complicated under the effect of a sunlit environment, and there are serious transverse and vertical temperature gradients, which will cause cracking and deformation of the structure. In this paper, an ANSYS temperature effect analysis model for ballastless track, considering box girder structure, is established based on the environmental information of the bridge and the characteristics of the structural system. The model considers the influence of solar radiation intensity, wind speed, air temperature, geographical location, bridge orientation, material parameters, and other factors on the boundary conditions, and can meet the needs of the daylight temperature response analysis and calculation of any complex bridge structure. On this basis, the effect and applicability of a solar reflective coating on ballastless track cooling are studied. The results showed that the calculated results of the finite element model agree well with the measured results. Under the high-temperature conditions in summer, sunlight and ambient temperature mainly have significant effects on the temperature and temperature gradient of the track slab, and the maximum vertical temperature gradient reaches 74.48 °C/m. The reflective coating can significantly reduce the track slab’s temperature and vertical temperature gradient, with a maximum temperature gradient reduction of 34%. The transverse temperature gradient of the track slab can be reduced by up to 54% by further application of the side reflective coating. This study can promote the application of reflective coatings on high-speed railway track structures.

Hydroarylation of alkynes via dual ortho-C-H functionalization of diaryl amines on a dicopper(I,I) platform.

A pyridine and morpholine-functionalized dicopper(I,I)-NHC complex (1) features both terminal and bridging coordination modes of NHC within the same molecule, and catalyzes dual ortho-C-H functionalization of diaryl amines for the hydroarylation of alkynes. A bimetallic construct in catalyst 1 allows sequential activation of ortho-C-H bonds of two aryl units to furnish a wide variety of 9,10-dihydroacridine derivatives without the explicit use of a directing group.

ВИВЧЕННЯ НАПРУЖЕНО-ДЕФОРМОВАНОГО СТАНУ ҐРУНТІВ НАВАНТАЖЕНИХ МОСТОІНЖЕНЕРНИХ СПОРУД

The article presents examples of the use of the method of modelling the influence of the ecological and geophysical state of the soil on bridgetype objects using the finite element method. A review of publications on modelling the stress-strain state of complex bridge structures under manmade environmental influences was conducted. Examples of studying the state of loaded soils at the base of bridges built in populated areas are considered. As an example, modeling of the stress-strain state of soils under two complex bridge structures was carried out. Changes in stress-strain of such soils are shown when the loads on bridges increase and when the type of bridge structures changes. The effectiveness of using the finite element method for modelling the processes of studying and changing stresses and deformations in rocks under complex structures and identifying typical manifestations of changes in the stress-strain state, which are important for a quick assessment of the soil condition, has been confirmed.

A novel synergistic covalence and complexation bridging strategy based on multi-functional biomass-derived aldehydes and Al(III) for engineering high-quality eco-leather

To get rid of the chrome pollution faced by the leather industry, we explored a novel engineering high-quality eco-leather technology based on the synergistic interactions between biomass-based aldehydes and Al(III). Firstly, dialdehyde xanthan gum (DXG) was prepared to covalently crosslink with the collagen fibers (CFs) via Schiff-base linkages under alkaline conditions, endowing the leather with a shrinkage temperature (Ts) of 80 °C and opening channels for the subsequent penetration of Al species (AL). Secondly, and for this latter purpose, the DXG-tanned leather was acidified to release part of the DXG from the leather according to the dynamic nature of the Schiff-base. Containing suitable oxygen-containing groups (OGs) with excellent complexation capabilities, the released DXG served as masking agents for AL, facilitating the penetration of AL into the inner CFs network for further complexation crosslinking. Consequently, a denser crosslinking network was constructed in the leather, and the crust leather exhibited higher Ts (82.2 °C), improved mechanical (tensile strength: 13.4 N/mm2, tear strength: 53.3 N/mm) and organoleptic properties than those of the DXG crust or AL crust leathers. This demonstrates that this synergistic covalence and complexation bridging strategy is a sustainable option to substitute highly restricted chrome tanning agent for eco-leather production.

Field-measurement-based local wind field characteristics on bridge deck of truss girder bridges in a deep-cutting gorge bridge site area

Affected by many factors, the local wind environment on the bridge deck is complex and changeable, and it seriously threatens traffic safety. To accurately evaluate the wind field on the bridge deck, this paper develops a system to monitor the actual local wind environment and applies it to field measurement of the wind parameters at different positions of a complex truss girder bridge. The results show that the wind parameters on the bridge deck, including wind speed, gust factor, and turbulence intensity, are different from the bridge site due to the influence of the ancillary facilities. Also, the wind profile of the local wind field on the bridge deck is more in line with the polynomial distribution, which makes the equivalent height of the wind load much higher than the vehicle gravity. It should be noted that the measured power spectrum of the bridge deck is quite different from the wind spectrum applicable to the bridge site area, so it is not appropriate to use the wind spectrum of the bridge site area to carry out the analysis of the windmill bridge, and a more suitable wind spectrum for bridge deck wind field is proposed.

Design and performance assessment of a novel self-anchored pedestrian suspension bridge

Conventional suspension bridge systems generally adopt a symmetrical layout, which has limited applicability in asymmetric urban terrain. However, the span capacity of the asymmetric bridge system is not as good as that of the conventional suspension bridge. Therefore, under the constraints of limited space, it is very urgent to design a new asymmetric pedestrian bridge with a strong crossing ability on the complex asymmetric terrain of the city. However, the design faced two challenges. (1) Because of the asymmetry of the structure, the cable balance equation and calculation theory of the new bridge need to be redetermined; (2) Because of the restriction of terrain conditions, it is necessary that optimize the preliminary design of the new bridge to achieve better mechanical properties. To address above problems, a new self-anchored continuous steel box girder composite system is proposed for use in suspension footbridges. This system uses connectors to reliably connect the suspension, main girders, and pylons. The continuous beam structure is used in the side span of the pedestrian bridge and the cable-stayed beam composite system is used in the main span. Therefore, the mechanical behavior of the structure is complex. To investigate the mechanical characteristics of the new structural system based on the preliminary conceptual design, the static and dynamic stability of the proposed structural system is comprehensively analyzed. A new force mode is proposed to improve the mechanical properties of the proposed structural system, and the applicability of the tuned mass damper to the new structural system was verified. Finally, an improved multi-objective genetic algorithm (I-MOGA) algorithm is hired to optimize the layout and mechanical properties of the proposed-composite system. The effectiveness and feasibility of the proposed-composite system bridge is verified to design for urban pedestrian bridges in limited terrain. Moreover, I-MOGA is used to optimize the design of the proposed mixed systems and obtain an improved structural layout for a complex pedestrian bridge in terms of forces, stability, and reliability. This study will provide a reference for the design of urban bridges on asymmetric terrain.

On the application limits and performance of the single-mode spectral analysis for seismic analysis of isolated bridges in Canada

Single-mode spectral analysis (SMSA) is a simple procedure efficiently used to evaluate the seismic demands of base-isolated bridges, particularly suitable for the design of simple bridges or preliminary design of complex bridges. However, bridge design codes, notably the Canadian code CSA-S6:19 (CSA-S6 2019), specify many limitations on the use of the method for final design. This paper evaluates the performance of SMSA and the efficiency of its limits of application as specified in the current codes through the results of a parametric study. The hysteretic properties of seismic isolation systems and the stiffness of bridge substructures are varied. Seismic demands predicted by SMSA and nonlinear time-history analyses (NLTHAs) are then compared, both inside and outside the current specified limit range in CSA-S6:19 (CSA-S6 2019). Results show that the most effective application conditions are those related to the maximum equivalent viscous damping and minimum restoring force. The upper limits of the effective period and the post-elastic period can be ignored. Further, to complement SMSA, a relation is proposed to estimate the expected residual displacement as a function of the restoring force at the design displacement. Regression relations allowing estimating the expected mean and confidence interval of the relative displacement deviation predicted by SMSA from that based on NLTHA are also proposed.

Research on the Reliability of Bridge Structure Construction Process System Based on Copula Theory

Various random factors in the bridge construction process directly affect the safety of the bridge life cycle. The existing theories on the reliability of bridge structure mainly focus on the reliability of components and the reliability of the bridge structure system in the completion and operation stages, while the research on the reliability of the structure system in the construction stage is relatively lacking. Therefore, this paper proposed using the Copula function to calculate the reliability index of the bridge structure construction process system. The basic theory of the Copula function was introduced in detail, and the formula was improved according to the actual situation of bridge construction. Finally, the sensitivity analysis of bridge system reliability was carried out. The research results showed that the method proposed in this paper based on Copula theory to calculate the reliability index of the bridge structure construction process system has strong applicability, simple calculation, and can be used in conjunction with the “interval estimation method”, which is suitable for large and complex bridge structural engineering. At the same time, the conclusion that the influence of failure mode correlation on structural reliability should not be ignored in the actual engineering construction process is confirmed.