An alternative to fiber reinforced polymer (FRP) materials adhesively bonded to the concrete substrate is the implementation of mechanically fastened FRP (MF-FRP) systems using steel anchors to secure the laminate to the substrate. The benefit of MF-FRP, compared to adhesive bonding for FRP flexural strengthening, is the speed of installation with unskilled labor, minimal or absent surface preparation under any meteorological condition and immediate use of the strengthened structures. Some of the potential shortcomings are: possible concrete damage during anchoring and limited opportunity of installation in the presence of congested internal reinforcement in the members to be strengthened. Laboratory testing and a number of field applications have shown the effectiveness of the MF-FRP method. In this paper, an analytical model is discussed for reinforced concrete (RC) members strengthened with MF-FRP strips. The model accounts for equilibrium, compatibility and constitutive relationships of the constituent materials; in particular, it accounts explicitly for the slip between the substrate surface and the FRP strip due to the behavior of the fasteners. The proposed flexural model, coupled with the computation algorithm, is able to predict the fundamentals of the behavior of RC flexural members strengthened with MF-FRP strips, in terms of both ultimate and serviceability limit states. Comparisons between the analytical predictions and the experimental results have been successfully performed.