Introduction Globally, oral cancer is the 15th deadliest cancer among humans. Diverse health education interventions have played a very significant role in the prevention of oral cancer. Of these interventions, digital interventions, especially mhealth-driven interventions, have been largely underutilized. So far, only two known educative mobile health applications (MHAs) for oral cancer exits; unfortunately, these two applications are not comprehensive and not inclusive for diverse populations. There is a need for a comprehensive and more inclusive MHA that can be used to educate the public about oral cancer. Objectives To co-develop, co-create, and test a comprehensive and inclusive MHA that can be used to educate the public about oral cancer. Methods The proposed study will be conducted and reported using the PRODUCES (PRoblem, Objective, Design, (end-) Users, Co-creators, Evaluation, Scalability) framework—this framework provides a novel approach which can be used to develop mhealth interventions through participatory action research methodologies. This study will have three parts. The first part will co-develop an eight-sectioned lay educational content on oral cancer through three-round Delphi consultations with thirty subject matter experts in the field of oral cancer and public health. Using the co-developed educational content, the second part of this study will co-create an educative MHA prototype on oral cancer through three-round Delphi consultations with twenty digital communication experts and persons at risk of oral cancer. Lastly, the third part will, through a three-arm, parallel, open-label randomized control trial, test and compare, among seventy-five young adults, the effectiveness, usability, uptake, and acceptability of the co-created MHA prototype on oral cancer against a web-based educational resource on oral cancer. Conclusion The outcomes of this study will co-produce and test an inclusive and comprehensive MHA prototype that can be used to educate diverse populations across the world about oral cancer.
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