To more clearly present the psychological mechanism and cognitive basis of humorous speech, this study measured college students using various scales, discussed the role of humorous coping in resolving their social anxiety and regulating their mental health, and attempted to construct a cognitive symbol working model from three dimensions: theory of innocence, modern semiotics, and conceptual integration theory. We used the proposed model to present the psychological mechanism and cognitive basis of humorous speech. This study found that humor coping is positively correlated with college students’ social anxiety, which is positively correlated with mental health. Affinity humor style and humor coping can positively predict college students’ communication anxiety, but affinity humor style has better predictive power. This research held that relevance is the general principle of communicative cognition and has become a space of conceptual synthesis network. The combination of conceptual fusion and deviation theory with conventional theory can help us better understand verbal humor and reveal its cognitive basis. There is a close relationship between humorous language and human psychological mechanisms. Finally, there is also a clear relationship between different psychological mechanisms and the structure of humorous language.