Commercialization Activities Research Articles

Durability Properties of Ambient Cured Geopolymer Mortar Made from Rice Husk Ash–Based Alkali Activator: A Comparative Study with Conventional Alkali Activator

Abstract Geopolymers/alkali-activated materials (AAMs) are widely regarded as ecofriendly and durable alternatives to portland-based cement concrete. However, commercial alkali activators, especially the sodium silicate used to manufacture geopolymers/AAMs, are associated with a significant amount of carbon emission during their production. In this study, the feasibility of using rice husk ash (RHA) as a source for an alternative sustainable alkali activator has been explored at ambient temperature curing, and the durability properties of the geopolymer mortars (GPM) has been investigated. Three different concentrations of sodium hydroxide (SH), i.e., 20, 24, and 27 wt. % solutions, have been taken for the synthesis of RHA alkali activator used in synthesis of GPM, and another GPM with conventional alkali activator has also been synthesized for comparative study. Durability studies such as water absorption, sorptivity, sulfate resistance, and acid resistance were evaluated extensively in terms of change in weight and compressive strength. The experimental results revealed that the GPM made with 24 wt. % SH-RHA–based activator solution (R24) has optimal performance considering all the durability parameters and has a close correlation to the results obtained for the control GPM made with conventional alkali activator (C24). The microstructural studies further revealed that the gel structure of the R24 is compact and homogeneous, similar to that of C24; however, the former has a N-A-S-H–dominated gel matrix and the latter consists of N-(C)-A-S-H–type gels.

Process optimisation and kinetic study for esterification of levulinic acid and n‐butanol using sulfonated titania–zirconia heterogeneous catalyst

AbstractBackgroundButyl levulinate (BL) was produced by the esterification of levulinic acid (LA) and n‐butanol (BOH) using a sulfonated nanocomposite of titania–zirconia as catalyst. A full factorial design was employed for studying the effects of reaction time, mole ratio and catalyst loading on LA conversion.ResultsThe synthesised catalyst was subjected to various characterisation techniques such as X‐ray diffraction, Fourier transform infrared spectroscopy, Brunauer–Emmett–Teller measurements, thermogravimetric analysis, temperature‐programmed desorption and scanning electron microscopy–energy dispersive X‐ray analysis indicating the presence of a nanocrystalline structure with good surface area and good stability at the operating temperature. The experimental data were analysed using the response surface method, and a complete quadratic regression model was built. The LA conversion was 85.37% for the optimised reaction conditions of 1:7 mole ratio, a catalyst loading of 1 wt% and a reaction time of 5 h at 110 °C. Based on the Langmuir–Hinshelwood–Hougen–Watson model, a kinetic model was developed. The activation energy was found to be 20.4 ± 0.8 kJ mol−1 from an Arrhenius plot. Reusability and leaching results are also reported.ConclusionThe catalyst exhibited good reusability and stability. Sulfonated TiO2–ZrO2 used to catalyse the reaction between LA and BOH to produce BL has proved to be a good candidate as a green catalyst. The results presented play an important part in directing subsequent research and commercialisation activities aimed at valorising LA to fuel additive. © 2023 Society of Chemical Industry (SCI).

The compound YK 3-237 promotes pig sperm capacitation-related events

Before fertilization of the oocyte, the spermatozoa must undergo through a series of biochemical changes in the female reproductive tract named sperm capacitation. Spermatozoa regulates its functions by post-translational modifications, being historically the most studied protein phosphorylation. In addition to phosphorylation, recently, protein acetylation has been described as an important molecular mechanism with regulatory roles in several reproductive processes. However, its role on the mammal’s sperm capacitation process remains unraveled. Sirtuins are a deacetylase protein family with 7 members that regulate protein acetylation. Here, we investigated the possible role of SIRT1 on pig sperm capacitation-related events by using YK 3-237, a commercial SIRT1 activator drug. SIRT1 is localized in the midpiece of pig spermatozoa. Protein tyrosine phosphorylation (focused at p32) is an event associated to pig sperm capacitation that increases when spermatozoa are in vitro capacitated in presence of YK 3-237. Eventually, YK 3-237 induces acrosome reaction in capacitated spermatozoa: YK 3-237 treatment tripled (3.40 ± 0.40 fold increase) the percentage of acrosome-reacted spermatozoa compared to the control. In addition, YK 3-237 induces sperm intracellular pH alkalinization and raises the intracellular calcium levels through a CatSper independent mechanism. YK 3-237 was not able to bypass sAC inhibition by LRE1. In summary, YK 3-237 promotes pig sperm capacitation by a mechanism upstream of sAC activation and independent of CatSper calcium channel.

Mechanical properties of alkali-activated slag based SIFCON incorporating waste steel fibers and waste glass

This experimental study focuses on sustainable slurry infiltrated fiber concretes (SIFCONs) by utilizing alkali-activated ground granulated blast furnace slag (GGBS) and waste fibers. The waste fibers were high-strength steel fibers recovered from scrap tires. Additionally, waste glass was employed as a substitute for commercial sodium silicate activator, contributing to the reutilization of a waste material. Such an approach stands out for its use of various waste materials to achieve a high-performance concrete primarily composed of recycled materials. Literature survey indicate that there are no studies available on concrete primarily composed of waste or recycled materials. In this study, the molarities of the activators were selected as 8 M and 14 M based on a prior research. Due to the fiber geometry and the associated bulking effect, a maximum waste fiber content of 5 % was adopted, with increments of 1 %. Load–deflection curves of the specimens were obtained in the bending test. Various mechanical properties, including compressive strength, splitting tensile strength, flexural strength, and fracture energy, were determined for the mixtures. The mechanical properties of the alkali-activated mixtures were improved compared to those of the reference concretes. Based on the mixture proportions and materials employed, alkali-activated mixtures in the study achieved compressive strengths exceeding 120 MPa and flexural strengths approaching 30 MPa. Furthermore, significant enhancements in fracture energies were observed. The strengths of the mixtures with waste glass, however, were lower compared to the other mixtures. Nonetheless, in summary, the study shows the promising potential of waste steel fibers and waste glass for the production of alkali-activated slag SIFCON. This approach not only enhances cost-effectiveness, sustainability, and mechanical properties but also reflects a significant step towards achieving a concrete composition that relies solely on waste materials.

Public value mapping to assess and guide governmental investments in energy and environmental justice: Studying the United States Department of Energy

If the U.S. federal government is going to successfully advance the causes of energy and environmental justice (EEJ) as recent policy has pushed for, how might federal programs and investments be assessed through the lens of these values beyond standard econometric ones? Federal agencies like the U.S. Department of Energy (DOE) play a significant role in setting long-term strategies and investments for energy technologies, but they generally use technocentric approaches and metrics, such as reductions in levelized cost of energy, to evaluate success. Understanding strategies and investments across a portfolio through the lens of EEJ requires novel approaches. We deploy a first-of-its-kind public value mapping focused how past programs in the DOE Water Power Technologies Office (WPTO) align with EEJ. By analyzing several thousand pages of congressional statutes, documented administration policies and executive orders, agency and office reports and publications, and semi-structured interviews of DOE staff and project collaborators, we focus on evaluating research, development, deployment, and commercialization activities promoting legacy (hydropower) and emerging (marine hydrokinetic) renewable energy technologies through the lens of EEJ. Our results provide a baseline according to which future programmatic efforts promoting EEJ in WPTO, DOE as a whole, and beyond can be compared. Our work provides a foundation for tools and processes that can be embedded into day-to-day staff actions that can guide federal investments related to EEJ and push for a more just and sustainable future.

TINJAUAN TERHADAP FAKTOR DEMOGRAFI DALAM PENGKOMERSIALAN PENYELIDIKAN DI UNIVERSITI

Commercialization of research is receiving increasing attention across various research fields in universities. The aim of this study is to identify the differences in demographic factors (gender, age, position, type of university, research experience, knowledge of commercialization, and research field) in research commercialization activities among lecturers in public universities in Malaysia. A cross-sectional descriptive research design was used, and a sample size of 155 lecturers was selected through simple random sampling from 20 public universities in Malaysia. Primary data was collected through a questionnaire in the form of a Google Form distributed via email. Subsequently, the collected data was analyzed using Statistical Packages for Social Sciences (SPSS) version 26.0. The results of the t-Test and ANOVA analyses indicated that there were no significant differences in research commercialization activities based on demographic factors, including gender, age, position, type of university, research experience, knowledge of commercialization, and research field. This demonstrates that academic researchers should not perceive demographic factors as barriers to their research commercialization activities. Therefore, the findings of this study are expected to benefit those involved in formulating various strategies and decision-making processes, with the aim of stimulating greater efforts in the commercialization of research results, especially at the university level.

Progress of Solid Oxide Electrolysis and Fuel Cells for Hydrogen Generation, Power Generation, Grid Stabilization, and Power-to-X Applications

Over the past 25+ years, Nexceris has been developing solid oxide cell (SOC) technology for power generation, energy storage and hydrogen production applications. Nexceris is vertically integrated SOC technology provider that develops and manufactures solid oxide electrode materials, interconnect coatings, planar electrolyte supported cells, and solid oxide stacks. Nexceris stacks are designed for low-cost manufacture and pressurized operation, and stacks have large repeat unit area for efficient packaging into megawatt-scale systems. Nexceris’ stacks are being tested in fuel cell, electrolysis, and reversible modes, with a focus on optimizing performance, efficiency, and durability. Current work at Nexceris includes long-term electrolysis stack durability testing, breadboard system testing of reversible SOC stacks, third-party stack validation testing, and SOC system design and demonstration testing. Nexceris also is exploring solid oxide co-electrolysis for converting steam and CO2 to syngas and the conversion of this syngas to fuels and chemicals. This presentation will provide an update on Nexceris’ solid oxide cell technology development and commercialization activities.

(Invited) Green Hydrogen R&D in South Africa

For decades, proton-exchange membrane (PEM) water electrolysis (WE) has been used mainly for oxygen generation in anaerobic environments. Over the past two decades, however, it has been increasingly used for hydrogen generation in the industrial sector at various and increasing scale. The PEMWE technology is also considered as a key one in the frame of the ongoing energy transition if the process of hydrogen generation by means of WE is linked to renewable energy sources, such as wind, solar, etc.Among other existing water electrolysis technologies, such as alkaline, solid oxide, the technology based on proton-exchange membranes has received a great deal of interest in South Africa. One of the reasons is endowment of South Africa with its PGM resources, such as platinum (Pt) and iridium (Ir) that are used in PEM water electrolysis (WE) catalytic components. As it is known, PEMWE technology is very well suited to accommodate intermittency of energy supply associated with renewables. PEMWE technology can also deliver relatively high-pressure hydrogen gas of high purity. South Africa has also superior endowment of both onshore wind and solar. It is known thar renewable energy (RE) is one of the largest operational cost components in the production of green hydrogen. Other factors contributing to the interest in green hydrogen water electrolysis technology in South Africa that are not obvious, but important, include large tracts of sparsely populated land with little alternative use, which can be dedicated for RE production. South Africa also has a suitable geographical position with deep water ports for the potential export of large quantity of hydrogen and its derivatives such as ammonia.Approximately 15 years ago South African Government approved national program HySA: Hydrogen South Africa that resulted in developing expertise and capacity to conduct research, development, and earlier commercial activities around green hydrogen production by means of water electrolysis. These activities include development of local IP at the components, stack and system levels. Recently, a number of “catalytic” projects have been identified in order to increase a demand in green hydrogen and stimulate investments.Recently, an international R&D project between South Africa and Japan was launched to develop further expertise in both green hydrogen and ammonia technologies [1]. Most recently, large companies, such as SASOL, made commitments to lead green hydrogen production at a large scale for the variety of applications, aiming at decarbonisation of mining and petrochemical sectors [2]. On the Governmental level, South Africa recently has approved its national hydrogen road map [3].This talk will provide a comprehensive update on the research, technology, and commercialisation activities in South Africa in the area of green hydrogen production.

What limits the innovation efficiency in China's ICT industry? A two-stage dynamic network slacks-based measure approach

ABSTRACT Based on the innovation value chain theory, the innovation process of the information and communication technology (ICT) firms is not only decomposed into R&D and commercialisation activities, but also its dynamic characteristics should be included in the evaluation system. To seek the underlying reasons for the inefficiency, a two-stage dynamic network DEA model within the SBM structure has been applied to assess the innovation efficiency along with the R&D capability and commercialisation performance. The results show that the innovation efficiency of the Chinese ICT industry shows a continuous decline due to the constraints of firms’ R&D capabilities. Similarly, the heterogeneity exists within the ICT industry; The four sub-industries has its own strengths, but they also exhibit high market efficiency and low R&D efficiency. Private companies show a higher level of R&D and commercialisation than SOEs in both stages.

PENGATURAN PERTANGGUNGJAWABAN SWASTA DALAM KECELAKAAN BENDA ANGKASA

Responsibility in space law is regulated in the 1967 Outer Space Treaty and the 1972 Liability Convention. These rules generally regulate the role and form of state responsibility in space activities that cause accidents. The current development of the legal space has begun to involve the private sector as the organizer of space activities, but so far regulations at the international and national levels have not regulated the roles and responsibilities of the private sector. To answer this problem, normative juridical research methods are used, namely legal research which bases the research results on secondary data, namely primary, secondary, and tertiary legal materials relating to personal responsibility in artificial space object accidents. From the research conducted, it can be concluded that the regulation of responsibility for space accidents that cause losses are borne by the state because the celestial bodies are registered in the name of the state, but in terms of payment of compensation incurred, it is borne by the state. space operator. The existing laws and regulations in Indonesia do not yet regulate the accountability mechanism for the private sector, because the Space Law only states that the private sector can play a role in space commercialization activities.

Fuelwood Value Chain in Northern Nigeria: Economic, Environment, and Social Sustainability Concerns

The increased fuelwood demand and commercialization activities in Nigeria over the years have incurred various sustainability issues and concerns along the fuelwood value chain. This study employed value chain analysis to examine the sustainability of the fuelwood value chain in Yobe, Nigeria, in relation to economic, environmental, and social aspects. From the analysis, it was found that fuelwood business activities were conducted by registered licensed actors (formally) and informally by non-licensed actors who do not register with the government agency that controls forest-related activities. Profit was not equally distributed along the value chain, whereby 65% of the total profits were reaped by the transporters. Natural forests were the main source of fuelwood, with 18 tree species being preferred and commonly traded by both formal and informal chain actors. Women’s participation in the formal fuelwood value chain was limited and mainly concentrated in the informal chain. The findings of this study can inform policymakers to enhance the sustainability of fuelwood production and trade along the value chain, especially in terms of profit sharing, exploitation of forest resources, and gender equality.

A Review of Recent Advances in Alkali-activated Materials from Silica-rich Wastes Derived Sodium Silicate Activators

Sodium silicate activators derived from silica-rich wastes have attracted increasing attention owing to their promotion on the sustainable production and development of alkali-activated materials (AAM). This paper presents the research progress on the feasibility of using silica-rich wastes-derived sodium silicate activator as an alternative to commercial sodium silicate activator in AAM. The basic factors affecting the quality of silica-rich wastes-derived sodium silicate activator are reviewed. The structure features between commercial sodium silicate and derivative sodium silicate are addressed and compared. Influences of the two different sodium silicates on flowability, mechanical properties, microstructure and durability are summarized and discussed. Previous studies reveal that utilizations of amorphously rich SiO2 containing materials, together with proper preparation technology, enable to produce highly reactive sodium silicate activators and as a consequence to obtain materials with comparable or even better performances as compared to the commercially available sodium silicate-AAM. Recommendations for future investigation are provided eventually.

Modulating the proliferative and cytotoxic properties of patient-derived TIL by a synthetic immune niche of immobilized CCL21 and ICAM1.

A major challenge in developing an effective adoptive cancer immunotherapy is the ex-vivo generation of tumor-reactive cells in sufficient numbers and with enhanced cytotoxic potential. It was recently demonstrated that culturing of activated murine CD8+ T-cells on a "Synthetic Immune Niche" (SIN), consisting of immobilized CCL21 and ICAM-1, enhances T-cell expansion, increases their cytotoxicity against cultured cancer cells and suppresses tumor growth in vivo. In the study reported here, we have tested the effect of the CCL21+ICAM1 SIN, on the expansion and cytotoxic phenotype of Tumor Infiltrating Lymphocytes (TIL) from melanoma patients, following activation with immobilized anti-CD3/CD28 stimulation, or commercial activation beads. The majority of TIL tested, displayed higher expansion when cultured on the coated SIN compared to cells incubated on uncoated substrate and a lower frequency of TIM-3+CD8+ cells after stimulation with anti-CD3/CD28 beads. Comparable enhancement of TIL proliferation was obtained by the CCL21+ICAM1 SIN, in a clinical setting that included a 14-day rapid expansion procedure (REP). Co-incubation of post-REP TIL with matching target cancerous cells demonstrated increased IFNγ secretion beyond baseline in most of the TIL cultures, as well as a significant increase in granzyme B levels following activation on SIN. The SIN did not significantly alter the relative frequency of CD8/CD4 populations, as well as the expression of CD28, CD25, several exhaustion markers and the differentiation status of the expanded cells. These results demonstrate the potential capacity of the CCL21+ICAM1 SIN to reinforce TIL-based immunotherapy for cancer patients.

Progress and development of syngas fermentation processes toward commercial bioethanol production

AbstractSyngas is created through the thermochemical conversion of biomass using gasification or pyrolysis and from CO‐rich off‐gases obtained from industries such as steel mills. The Wood–Ljungdahl metabolic pathway, or one of its variations, is used by acetogenic bacteria to convert syngas components (CO, H2, and CO2) to alcohols and other compounds. Many factors affect how well syngas is fermented, including the bacteria species used, syngas composition, medium components, bioreactor type, operational parameters used and the gas–liquid mass transfer rate. These parameters impact carbon and electron flow in the bacteria, influencing the distribution, concentration and metabolic end‐product yield, which determines process feasibility. This article focuses on gas composition, microorganisms, gas–liquid mass transfer fermentation strategies, medium design and commercialization activities to develop the syngas fermentation processes. © 2023 Society of Industrial Chemistry and John Wiley & Sons Ltd.

Preparation and curing method of red mud-calcium carbide slag synergistically activated fly ash-ground granulated blast furnace slag based eco-friendly geopolymer

The commercial alkali activators could account for more than 50% of the cost for producing geopolymers. Thus, to lower the carbon footprint of geopolymer by avoiding the utilization of energy-intensive commercial alkali activators, a novel eco-friendly geopolymer was synthesized from 100% solid wastes comprising red mud (RM), calcium carbide slag (CS), ground granulated blast furnace slag (GGBS) and fly ash (FA) in this study. Effects of GGBS contents and curing conditions on the compressive strength, fluidity and water requirement for normal consistency were investigated. The hydration products in the binders cured at different conditions were characterized by X-ray diffraction (XRD), thermogravimetric (TG), Fourier transformation infrared spectroscopy (FTIR) and scanning electronic microscopy (SEM). The results showed that GGBS improves the compressive strength as well as the mortar fluidity and reduces the water requirement for normal consistency of the geopolymer. Raising the curing temperature up to 60 °C and prolonging the heat curing duration to 12 h facilitate the dissolution and polymerisation of the FA-GGBS and therefore increase the amount of gel and crystalline products, whereas excessive heat-curing at temperatures higher than 60 °C and durations longer than 12 h causes shrinkage cracks at later age, which was detrimental to the compressive strength. The mineralogical characterization revealed that the amount of gel governs the strength development and heat curing favors the formation of secondary crystalline phase hydrotalcite. The developed binder can be used to produce low-carbon clinker-free concrete blocks to improve the sustainability of concrete industry.

Development of low-carbon alkali-activated materials solely activated by flue gas residues (FGR) waste from incineration plants

Flue gas residues (FGR), a waste from incineration plant was utilized as an alternative alkaline activator to energy intensive and costly commercial activators. Fly ash (FA) and slag were used as precursors materials along with the FGR to produce low-carbon and cost-effective alkali-activated materials (AAMs). Reaction products and micromechanical properties were investigated by advanced microstructure analysis techniques. Results from the infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), scanning electron microscopy (SEM) and nanoindentation indicated that reaction products were comprised of N-A-S-H gel as a major reaction product along with the hybrid gel (C–N-A-S-H) and C-A-S-H gel. SEM-EDS and nanoindentation results showed that the formation of C-A-S-H gel was directly related to the content of FGR. The increase in volume of Ca-based reaction products (C–N-A-S-H and C-A-S-H) was associated with the activation of slag in presence of Na2SO4. Besides N-A-S-H gel, some new reaction products (zeolite, apatite and berlinite) were also observed from XRD analysis of pastes. The compressive strength of AAMs was in the range of 33.5–39.6 MPa and was in line with microstructure analysis results. Leaching concentrations of Ag, Ba, Cd, Cu and Zn heavy metals in FGR were 0.10, 0.40, 0.63, 0.26 and 1.65 mg/L respectively and below the regulatory limits and it was classified as a non-hazardous material.

Recycling of red mud and flue gas residues in geopolymer aggregates (GPA) for sustainable concrete

This study proposed simultaneous utilization of red mud (RM) and flue gas residues (FGR) as a partial replacement of traditional precursors and energy-intensive activators. Reaction mechanisms of geopolymer pastes were investigated through isothermal calorimetry, X-ray diffraction, thermogravimetry and infrared spectroscopy, by varying the dosage of RM (40%) and FGR (24%, 32%). Results showed that use of RM and FGR as a replacement of FA and commercial activator had a limited influence on the compressive strength. RM and FGR participated in reaction at a slower rate. After optimization, heat-cured FGR0.32 mix was selected to manufacture geopolymer aggregates (GPA). Engineering properties, cost analysis and environmental impact of GPA were evaluated. Natural aggregates (NA) were replaced by GPA at replacement levels of 25%, 50%, 75% and 100% by volume to prepare concrete. GPA concrete with 25% and 100% replacement level could achieve the 94.6% and 86.6% of NA concrete strength respectively at 28 days age.

Comparative Study on LC3-50 with OPC Concrete Using Raw Materials from Pakistan

The cement industry is expanding rapidly around the globe, despite its significant contribution to global carbon dioxide emissions. Likewise, in Pakistan, the cement industry produces million tons of cement and has a history of contributing as high as 10% of the country’s carbon dioxide emissions annually. The most effective technique for reducing carbon dioxide emissions is to use supplementary cementitious materials (SCMs). Limestone Calcined Clay Cement (LC3-50) is a recently developed cement blend comprised of 50% clinker, 30% calcined clay, 15% raw limestone, and 5% gypsum by weight. The focus of this research is to assess the mechanical properties and durability performance of LC3-50 cement composition formulated using raw materials from Pakistan. The comprehensive case study would help advance the research and commercialization activities in the country. In this study, compressive strength, split tensile, flexural, and pull-out tests were performed for evaluating the mechanical properties. For the assessment of durability, water permeability, sorptivity, carbonation, and rapid chloride penetration test (RCPT) tests were performed as per the available standards. It is concluded that the use of LC3-50 instead of ordinary Portland cement (OPC) improved the strength and durability of the end concrete.

Transition Modelling of Land Use Land Cover Dynamics in Bardez Taluka of Goa-India (1991-2021)

In the age of global climate change, land use and land cover mapping help us to understand the vital modifications taking place in our environment. LULC mapping assumes great significance in planning, management of resources and keeping track of various programmes at different levels. The data acquired from the land use and land cover investigations are vital for policy formulation and sustainable development of our towns, cities and villages and also to track the disorganized growth of urban areas. Tourism is a tool for economic development in many developing countries of the world. The unplanned tourism growth has led to many ecological problems. This study makes an earnest effort to examine the LULC change using the transition model in the Bardez taluka, which is a well-known global tourist destination in Goa, India. The study has been investigated by using satellite imageries and GIS technologies have been used to analyse the changes occurring in LULC patterns for the years 1991, 2001 and 2021. The result indicates that the area under the built-up class has increased substantially by 11.12 sq. km. as a result of the rise in commercialization, tourism growth and tourism-related activities. Bardez taluka is known for some of the most breath-taking beaches in the world. During 2019-20, just before Covid-19, about 25, 33,234 domestic and 2, 74,840 foreign tourists visited the enchanting beaches of Bardez taluka. Land use classes such as residential, commercial and services, industrial, transportation and utilities also witnessed the growth in their land use and land cover classes whereas classes like agricultural land, coconut plantation, cashew plantation, barren land, DM and FDM forest land, open scrub and fairly dense scrub witnessed a negative change in their class values.

Stakeholder contributions to commercialization and market creation of a radical innovation: bridging the micro- and macro levels

PurposeSuccessful commercialization is crucial to innovative firms, but further investigation is needed on how diverse stakeholders can contribute to the commercialization of a radical innovation that requires particular market creation support. This paper aims to, therefore, analyze the key stakeholders and their contributive activities in commercialization and market creation, particularly in the case of radical innovations.Design/methodology/approachThis study relies on qualitative research design including interviews with key stakeholders, such as regulators, scientists, experts, licensing partners, core company representatives and extensive secondary data. This single-case study concerns a functional food product, which is a radical innovation requiring the development of a novel product category positioned between the food and medicine categories in global market settings. Since its market launch in 1995, the involvement of multiple stakeholders was needed for its successful commercialization in over 30 countries.FindingsResults uncover the contributions of diverse stakeholders to commercialization and market creation, particularly of radical innovation. Stakeholders performed market creation activities such as regulating the marketing and labeling of food products, conducting safety assessments, revealing and validating the positive health effects of the novelty and raising awareness of healthy living and cardiovascular health. The commercialization activities included distributing the products overseas, applying the ingredient to different food products and making the products available for users.Research limitations/implicationsThis single-case study provides an overview of the positive stakeholder activities with contributions to market creation and commercialization of functional food innovations. Although the user perspective was not included in the empirical part of this study because of our focus on B2B actors, users of the innovation can contribute to R&D activities to a great extent.Originality/valueThe developed framework of stakeholders’ contributive activities in radical innovation commercialization and market creation contributes to literature discussing market creation as well as commercialization within the marketing and innovation management research fields. This work also generates practical advice for managers who commercialize (radical) innovations.