Commercialization Activities Research Articles

A critical review of activated carbon for CDI electrodes, emphasizing its biomass and commercial sources, activation methods, performance analysis, and future advancements

A critical review of activated carbon for CDI electrodes, emphasizing its biomass and commercial sources, activation methods, performance analysis, and future advancements

The Past, Present, and Future of Plant Activators Targeting the Salicylic Acid Signaling Pathway.

Plant activators have emerged as promising alternatives to conventional crop protection chemicals for managing crop diseases due to their unique mode of action. By priming the plant's innate immune system, these compounds can induce disease resistance against a broad spectrum of pathogens without directly inhibiting their proliferation. Key advantages of plant activators include prolonged defense activity, lower effective dosages, and negligible risk of pathogen resistance development. Among the various defensive pathways targeted, the salicylic acid (SA) signaling cascade has been extensively explored, leading to the successful development of commercial activators of systemic acquired resistance, such as benzothiadiazole, for widespread application in crop protection. While the action sites of many SA-targeting activators have been preliminarily mapped to different steps along the pathway, a comprehensive understanding of their precise mechanisms remains elusive. This review provides a historical perspective on plant activator development and outlines diverse screening strategies employed, from whole-plant bioassays to molecular and transgenic approaches. We elaborate on the various components, biological significance, and regulatory circuits governing the SA pathway while critically examining the structural features, bioactivities, and proposed modes of action of classical activators such as benzothiadiazole derivatives, salicylic acid analogs, and other small molecules. Insights from field trials assessing the practical applicability of such activators are also discussed. Furthermore, we highlight the current status, challenges, and future prospects in the realm of SA-targeting activator development globally, with a focus on recent endeavors in China. Collectively, this comprehensive review aims to describe existing knowledge and provide a roadmap for future research toward developing more potent plant activators that enhance crop health.

Differences in human and commercial hybrid pig platelet activation induced by borosilicate glass beads in a modified chandler loop-system.

The pig (Sus scrofa) is the most widely used large animal model in Europe, with cardiovascular research being one of the main areas of application. Adequate refinement of interventional studies in this field, meeting the requirements of Russell and Burch's 3 R concept, can only be performed if blood-contacting medical devices are hemocompatible. Because most medical devices for cardiovascular interventional procedures are developed for humans, they are tested only for compatibility with human blood. The aim of this study was therefore to determine whether there are differences in behavior of human and porcine platelets from commercial hybrid pigs when they come into contact with borosilicate glass, which was used as an exemplary thrombogenic material. For this purpose, changes in platelet count, platelet volume and platelet expression of the activation markers CD61, CD62P and CD63 were measured using a modified chandler loop-system simulating the fluidic effects of the bloodflow. Commercial hybrid pig and human platelets showed significant adhesions to borosilicate glass but the commercial hybrid pigs platelets showed a significantly higher tendency to adhere to borosilicate glass. In contrast to human platelets the platelets of commercial hybrid pigs showed significant activation after 4 to 8 minutes exposure to borosilicate glass and there were differences among the ratios of surface and activation markers in between the platelets of both species.

Challenges and Barriers to Commercialization of Health Sciences Research Results: A Qualitative Study

Background: In today's world, due to intense competition and the rapid pace of production, exploiting knowledge and converting it into economic returns has become a critical management issue for academics and capital owners. Commercialization activities can impact the educational and research programs of universities, potentially leading to resistance against them. Objectives: The current study was conducted to identify the challenges of the commercialization process in health science research. Methods: This qualitative study was conducted between June and December 2022 in Tehran province, Iran. Data were collected using semi-structured interviews with 22 key individuals, including university management and technology experts, as well as CEOs and experts from knowledge-based companies, selected through purposive sampling. The interview guide was designed based on four in-depth interviews, theoretical foundations, and comparative study findings. The obtained data were analyzed using the conventional content analysis method in MAXQDA 10 software. Results: The challenges of the commercialization process for health sciences research results were categorized into six main themes and 16 sub-themes. The main themes identified in this study were rules and regulations, societal culture, university management and infrastructure, human resources, financial systems, and organizational cooperation with industry. Conclusions: Policymakers, especially senior health managers, can create a suitable platform for the optimal use of resources and the expansion of targeted relationships between universities and industries by incorporating economic insight into academic services. By compiling relevant laws and guidelines, optimizing resource management, achieving financial independence for universities, and increasing the productivity of health research, the high costs associated with the commercialization of academic research projects can be reduced.

On-Demand Production of Two Commercial Plant Activators, Tiadinil and Methiadinil, under an Integrated Continuous Flow System

On-Demand Production of Two Commercial Plant Activators, Tiadinil and Methiadinil, under an Integrated Continuous Flow System

Insulin-Mimetic Activity of Herbal Extracts Identified with Large-Scale Total Internal Reflection Fluorescence Microscopy.

Diabetes mellitus is a spreading global pandemic. Type 2 diabetes mellitus (T2DM) is the predominant form of diabetes, in which a reduction in blood glucose uptake is caused by impaired glucose transporter 4 (GLUT4) translocation to the plasma membrane in adipose and muscle cells. Antihyperglycemic drugs play a pivotal role in ameliorating diabetes symptoms but often are associated with side effects. Hence, novel antidiabetic compounds and nutraceutical candidates are urgently needed. Phytogenic therapy can support the prevention and amelioration of impaired glucose homeostasis. Using total internal reflection fluorescence microscopy (TIRFM), 772 plant extracts of an open-access plant extract library were screened for their GLUT4 translocation activation potential, resulting in 9% positive hits. Based on commercial interest and TIRFM assay-based GLUT4 translocation activation, some of these extracts were selected, and their blood glucose-reducing effects in ovo were investigated using a modified hen's egg test (Gluc-HET). To identify the active plant part, some of the available candidate plants were prepared in-house from blossoms, leaves, stems, or roots and tested. Acacia catechu (catechu), Pulmonaria officinalis (lungwort), Mentha spicata (spearmint), and Saponaria officinalis (common soapwort) revealed their potentials as antidiabetic nutraceuticals, with common soapwort containing GLUT4 translocation-activating saponarin.

Solar-driven high-performance biomass porous carbon for efficient CO2 capture

Temperature swing adsorption (TSA) based on solid adsorbents is an efficient CO2 capture technology, but the temperature swing process is energy-intensive. Utilizing solar energy to regenerate adsorbents during the CO2 swing adsorption process can decrease energy consumption. This work reports a novel high-performance biomass porous carbon for efficient CO2 capture and separation in the solar-driven TSA process. Inspired by the distinctive internal expansion structure of succulents, the adsorbent is synthesized using succulents as precursors with a large specific surface area (1715 m2/g) and high solar absorbance (90.38 %), resulting in high CO2 adsorption capacity and solar thermal conversion capacity. It achieves a remarkable working capacity of 30.94 mg/g at a low desorption temperature (60 °C) in the solar-driven TSA process with a light intensity of 600 W/m2, 80.7 % higher than commercial activation carbon. The proposed biomass porous carbon derived from succulent plants has substantial potential for application in the solar-driven TSA process.

Compressive Strength and Microstructure of Carbide Slag and Alkali-Activated Blast Furnace Slag Pastes in China

The alkali-activated blast furnace slag is attracting significant attention in replacing Portland cement due to several characteristics similar to cement hydration. However, there are a few practical problems with commercial alkali activators, such as the fast setting time, relatively high costs, and significant CO2 emissions during preparation. Thus, discovering industrial residues possessing inherent alkalinity are urgent. This study proposes the use of carbide slag at levels of 0%, 5%, 10%, 15%, 20%, and 30% and alkali at levels of 1%, 2%, 3%, 4%, 5%, 6%, 8%, and 10% activated blast furnace slag. The compressive strength and microstructure of carbide slag and alkali-activated blast furnace slag (CAB) pastes were examined using X-ray diffraction analysis (XRD), Differential Scanning Calorimetry/Thermogravimetric Analysis (DSC/TG), Fourier transform infrared spectroscopy (FTIR) and Scanning electron microscopy (SEM). The results revealed that the addition of carbide slag produced more hydrotalcite-like phase as well as decreased the content of ettringite (AFt) and the calcium–silicate–hydrate (C-S-H) gel, which decreased the compressive strength of the CAB pastes. At the age of 28 days, when the dosage was 5%, 10%, 15%, 20%, and 30%, the compressive strength of CAB mixes decreased by 2.1%, 7.1%, 9.2%, 9.8%, and 28.1%, respectively. The addition of NaOH promoted the formation of AFt, and there was an optimum level of NaOH corresponding to the high compressive strength of paste. At the age of 3 days and 7 days, the compressive strength reached its maximum at the dosage of 6% NaOH, which was 24.8 MPa and 36.3 MPa, respectively. However, at the ages of 14 days and 28 days, the compressive strength increased as the dosage of NaOH increased to 5%, which was 43.3 MPa and 44.5 MPa, respectively. The water curing could both enhance the early and later strength, the compressive strength of 23.3 MPa was gained at 3 days, and this increased by 16.3%, 24.0% and 36.9% at 7 days, 14 days and 28 days, respectively. Therefore, water curing was suitable for the strength development of CAB pastes.

Synthesis of solid sodium silicate from waste glass and utilization on one-part alkali-activated materials based on spent oil filtering earth.

Alkali activated materials (AAMs) commonly known as geopolymers are considered ecofriendly substitutes for Portland cement. However, these materials still have a significant environmental impact, owing mainly to the use of activators based on commercial chemical products. In this sense, this research focuses on the production and use of waste glass-derived activators AAMs as an alternative to commercial activators. Using a thermochemical synthesis method, activator compositions were systematically designed to achieve predefined activator modulus (Ms = SiO2/Na2O = 0.5; 1.0 and 1.5). These alternative activators were studied by XRD, FTIR and SEM techniques. Additionally, one-part AAMs were manufactured using spent oil filtration earth (SOFE) as precursor and activator with optimum modulus Ms = 1.0. The influence of the Na2O dosage was studied (10; 20 and 30g of Na2O per every 100g of SOFE) as well as the influence of the activator modulus maintaining the optimum dosage of 20g Na2O per 100g of SOFE. As a control, two-part AAMs were also synthetized with the optimum dosage and modulus employing commercial activators (NaOH + Na2SiO3 solution). Results indicate that the modulus of the alternative activator and especially the Na2O dosage have a significant influence on the technological properties of AAMs based in SOFE, with an optimum compressive strength (35.8MPa) for the addition of 20g of Na2O per every 100g of SOFE using activator with modulus Ms = 1.0. This research embodies a sustainable approach to AAM production and suggests waste glass as a valuable raw material for sodium silicate synthesis intended for the one-part activation of spent filtering earth from the agri-food industry, aligning with the principles of circular economy and sustainable development goals.

Sustainable alternative activators from the textile mercerizing water for the durable and cost-effective flyash-GGBS based geopolymer concrete

By considering the current global challenges such as greenhouse gas emission and waste disposal management, the exploration of geopolymer concrete is highly focused now-a-days. On the other hand, the use of costlier commercial activators acted as the major drawback for the practical existence. Although the recent geopolymer researchers suggested the use of alternative activators from various resources such as palm oil ash, olive ash etc, the application of which are not appreciably promoted due to the complex derivation process. To overcome these effects, in this paper, first time, an attempt is initiated to develop a cost-effective geopolymer concrete by using textile mercerizing water as an alternate activator system. The viability of using mercerizing water instead of commercial sodium hydroxide activator was studied initially. By conducting the pH electrode test and Infrared Analysis, the alkalinity and the presence of sodium metal cations responsible for the reaction kinematics were confirmed. Also, the molar concentration of sodium cations in the mercerizing water was quantified using chemical titration analysis. The feasibility of using mercerizing water in the preparation of geopolymer was assessed using workability, mechanical strength and sustainability. From the results, it was inferred that the developed geopolymer concrete with 100 % textile mercerizing water exhibited the maximum strength of 46.9 MPa, 5.16 MPa and 5.81 MPa respectively under compression, tension and flexure which are almost equivalent and slightly better than the control geopolymer concrete. Also, the developed geopolymer concrete using 100 % textile mercerizing water and the combined flyash-GGBS binder system showcases the highest post-fire residual strength and 48 % reduced water absorption. The cost of construction of geopolymer concrete was significantly reduced by 58.43 % and showed 10.28 % reduced carbon footprint due to the complete replacement of sodium hydroxide solution using textile mercerizing water. The findings of this research work will lead to the development of equivalent molar sustainable activator from the textile mercerizing water and the exploration of eco-friendly and durable geopolymer concrete in an affordable price.

Innovative use of hazelnut shell ash as an alkali activator: A comparative analysis with commercial activators

The selection of alkali activators is crucial in determining the characteristics of alkali-activated materials (AAMs). The activators are typically derived from commercial sources and significantly affect the ecological impact of AAMs across different life cycle categories. Hence, this study investigated the utilization of hazelnut shell ash (HNA) as an alternative activator in the synthesis of AAMs for the first time. HNA is evaluated as a green waste-derived option in place of sodium hydroxide (NaOH) and potassium hydroxide (KOH) in blast furnace slag (BFS) activation. A comparative investigation was conducted on the fresh, mechanical, and microstructural properties of AAMs activated with HNA, NaOH, or KOH. The experimental results showed that the compressive strength of HNA-activated AAM specimens can reach up to 26.8 MPa at 28th days, equivalent to mixtures activated with 2.0 M NaOH and 2.2 M KOH. It was observed that HNA alleviates the early-stage reactions by providing sufficient alkalinity due to its K2O content, contributes to gel formation with its calcium and silicon rich chemical composition, and also improves the compressive strength by acting as micro-aggregate.

Improved macro-microscopic characteristic of gypsum-slag based cementitious materials by incorporating red mud/carbide slag binary alkaline waste-derived activator

The expensive cost and high carbon footprint of commercial alkaline activators hindered the promotion and industrialization of geopolymers. The rising demand for geopolymer as low carbon and excellent building materials will lead to enormous research works towards to low carbon alkaline activator. This study aimed to explore the impact of red mud (RM)/carbide slag (CS) binary alkaline wasted-derived activator (RCA) on the macroscopic and microscopic properties of RCA activated cementitious materials (RCM) prepared with titanium gypsum (TiG) and granulated blast furnace slag (GBFS). It is proposed to adjust the pH value of solid waste powder for calibrating the waste-derived activator, prepare RCM and explore the relationship between its mechanical properties and hydration products. The research showed that the highest flexural and compressive strengths at 28 days occurred with a dosage of 0.8 wt% CS, meeting the strength requirements of 52.5 R Portland cement. It is worth noting that RCM with binary alkaline waste-derived activators with appropriate pH values can exhibit excellent early mechanical properties. Raising the pH of RCA significantly improves the compressive and flexural strength, increasing them to 30.7 MPa and 6.3 MPa at 3 d, and to 60.7 MPa and 10.8 MPa at 28 d. The primary hydration products of RCM include C(N)-A-S-H gels, ettringite, and gypsum crystal phase, which contribute to the development of mechanical strength. Due to the difference in the alkaline environment required for the growth of C(N)-A-S-H gel and ettringite crystal, the increase in RCA pH value has been found to both inhibit the growth of ettringite to a certain extent and promote the precipitation of C(N)-A-S-H gels, improving the chemical structure of the hydration products and the pore distribution characteristics of the RCM. Furthermore, the research has been successfully applied in a pilot test in Jiaozuo, China. RCM introduces a novel concept for the efficient and industrial-scale utilization of solid waste. This study can provide a fundamental academic and industrialized support and a novel concept for the whole solid waste cementitious materials especially from alkaline industrial solid wastes such as RM and CS.

Production of cleaner binders by reusing agricultural by-products: An approach towards zero cement concrete for sustainable future infrastructure

Alkali-activated binders are considered a low carbon alternative for cement. However, it is important to address the carbon dioxide emission and high cost associated with the currently used commercial activators. Hence, recent studies focus on developing sustainable, low-cost alternative activators. Although rice husk ash derived activator is a potential alternative to commercial activators, studies on rice husk ash derived activator is highly limited. Hence, the present study focuses on the performance evaluation of alkali-activated binders using rice husk ash derived activators. The effect of activators is studied for bagasse based binary and ternary alkali-activated binders. Moreover, the influence of rice husk ash derived activators is meticulously compared with commercial sodium silicate derived activators. In addition, the influence of heat and ambient curing was also investigated. Mechanical, durability and microstructural properties of bagasse ash based alkali-activated binders were assessed. Bagasse ash-fly ash based binders activated using rice husk derived activators yielded the maximum compressive strength. However, bagasse ash-slag based binders with commercial sodium silicate activators exhibited higher performance than rice husk ash derived activators. In the case of bagasse ash-slag-fly ash based ternary binders, specimens activated using the rice husk ash derived activator had better performance than specimens activated using the other conventional activators. Even though the addition of 10% bagasse ash increased the performance of fly ash based binders, the incorporation of bagasse ash reduced the performance of slag and ternary alkali-activated binders. The results also showed that the rice husk ash based activator is a feasible alternative for the activation of bagasse based precursors to generate desirable mechanical strengths and durability.

Innovative one-part Alkali activated binder from activator derived from agricultural waste: Synthesis and application for sustainable construction

Commercial powder activators are commonly used to produce one-part alkali-activated binders (AAB) despite their manufacturing method using more energy and generating more CO2 emissions. To address this concern, the study employed a mechanical process to synthesize an agricultural waste-based powder activator, derived from rice husk ash (RHA) and NaOH powder at six different ratios. Paste samples were prepared by blending the derived activator with ground granulated blast furnace slag (GGBFS) precursor in a 1:4 ratio. Fresh properties and compressive strength (range of 33–77 MPa) was evaluated. Besides, microstructural analysis and ecological factors were estimated, including embodied CO2 emissions and energy analysis, and the approach employed in this investigation significantly reduced both embodied CO2 emissions and embodied energy requirements compared to conventional practices. The result indicates that the activator powder synthesized in this study can produce AAB with qualities comparable to Portland cement.

Not seeing the forest for the trees? A systems approach to the entrepreneurial university

The idea and practice of the entrepreneurial university has emerged in response to growing expectations of universities contributing to economic development and has, in turn, been subject to a growing body of research. However, much of the work is focused on individual activities or institutions, typically overemphasising commercialisation activities and certain types of universities. Furthermore, much of this research is de-contextualised and does not consider the systems in which universities operate. As a result, we have a variety of unit theories of constituent parts of the entrepreneurial university without considering the wider (feedback) effects and implications — in other words: we are, in effect, not seeing the forest for the trees. Drawing on in-depth quantitative and qualitative field work and the literature, we develop a programmatic theory of the entrepreneurial university and the institutionalised entrepreneurial activities. Using causal loop diagrams, we capture the systemness and the interdependencies between universities’ entrepreneurial activities and their dynamic capabilities. The model highlights how universities are part of a larger system and how this influences their external engagement activities. The result is a more holistic understanding of entrepreneurial universities that reconciles existing work and guides future research. We discuss practical implications and policy levers derived from this systemic perspective.

Potensi ekstrak maggot lalat tentara hitam Hermetia illucens (Linnaeus) dalam regulasi mekanisme antioksidan selular dan antiradang: Kajian in silico

Potensi larva (maggot) lalat tentara hitam (black soldier fly/BSF, Hermetia illucens (Linnaeus)) sebagai sumber biofarmaka khususnya antioksidan dan atau antiinflamasi belum diteliti lebih lanjut. Penelitian ini bertujuan mengidentifikasi senyawa dalam ekstrak maggot BSF yang berpotensi mengaktifkan mekanisme persinyalan antioksidan. Maggot BSF yang telah diberi pakan limbah pertanian diekstrak dengan metode maserasi menggunakan pelarut air, metanol, dan aseton. Analisis dengan liquid chromatography-mass spectrometry (LC-MS/MS) terdeteksi 40 senyawa kimia, yaitu 15 dari ekstrak air, 13 dari ekstrak metanol, dan 12 dari ekstrak aseton. Sebagian besar (90%) dari senyawa tersebut memiliki skor bioavailabilitas baik (= 0,55 atau lebih) dengan toksisitas relatif rendah (500 mg/Kg<LD50<5000 mg/Kg BB). Penambatan molekuler memprediksi 26 senyawa bioaktif berpotensi mengaktifkan mekanisme antioksidan di dalam sel via faktor transkripsi NRF2, lebih baik daripada aktivator NRF2 komersil. Senyawa terbaik adalah senyawa larut air dengan PubChem CID: 73775828. Senyawa ini mengikat protein Keap-1 (PDB ID: 6FFM) yang menghambat persinyalan NRF2 dengan energi bebas Gibbs (ΔG) = -6,08 Kkal/mol dan konstanta disosiasi (Kd) = 3,58 × 10-5µM. Adapun penghambatan peradangan via NF-kappa B terbaik ditunjukkan oleh senyawa larut air verpacamide A yang mengikat enzim inhibitor NF-kappa B kinase (IKK2) (PDB ID: 4KIK) dengan ΔG = -5,024 kkal/mol; Kd = 0,207 × 103 µM. Potensi ini lebih baik dari yang ditunjukkan oleh aspirin. Dengan demikian, ekstrak maggot BSF merupakan sumber biofarmaka yang berpotensi mengaktifkan persinyalan antioksidan selular dan menghambat terjadinya inflamasi.

Strategic Orientation and New Product Development Performance of Academic Spin-Offs: The Importance of Team Cohesion and Team Heterogeneity

Prior studies have highlighted the importance of team heterogeneity and team cohesion in supporting academic spin-offs during their commercialization activities. However, there has been little insight into the role of strategic orientation, namely speed to market and product performance, in moderating the relationship between team characteristics and market performance in the new product development process. From the analysis of 105 academic spin-offs, this article suggests that team heterogeneity is more likely to support a strategic orientation focusing on product performance, whereas team cohesion supports both speed to market and product performance. This article provides both theoretical and practical recommendations for managing academic spin-offs for the development of new products, especially highlighting the importance of building a heterogeneous team while at the same time maintaining cohesion among team members.

Navigating intellectual property (IP): A comparative analysis of Australian universities' IP policies.

The push towards research commercialisation at universities has highlighted the importance of intellectual property (IP) policies in fostering innovation and guiding and managing research commercialisation activities. This paper undertakes a content analysis of intellectual property policies of all (37) Australian public universities, focusing on policy objectives, definition of IP, ownership of IP created by different creators, and distribution of net commercialisation revenues. It is found that all universities assert ownership over staff-created IP, particularly when related to employment or utilisation of university resources. For students, policies tend to balance their rights with university interests, with nuanced approaches for different types of student participation, but the focus of most policies was on postgraduate students engaging in research activities. While some policies had clear arrangements for IP created by visitors and affiliates and Indigenous cultural and intellectual property (ICIP), about a quarter of policies did not specify arrangements for these groups. Revenue sharing arrangements vary but generally award something between a third to a half of net revenue to creators, to both acknowledge their contribution and incentivise further innovation. Policies included a broad spectrum of objectives, from protecting and commercialising IP to fostering innovation and societal benefit, reflecting varying strategies across the higher education sector. Policies could benefit from further clarity in certain areas such as the rights of students or other creator groups. Research is needed to assess the effectiveness of these policies and their influence on innovation and commercialisation activities.

Implikasi Hukum Terhadap Peningkatan Sampah Ruang Angkasa Akibat Aktivitas Komersialisasi Ruang Angkasa

This research aims to analyze the legal implications of the increase in space debris generated through space commercialization activities. This research uses a normative legal method using a qualitative approach to determine the application of law in commercial activities carried out in space. The results of this study, namely: (1) the increase in space junk cases caused by commercial activities in space is increasing until 2022 due to various satellites being launched and causing junk to scatter freely in space. The rules of the Outer Space Treaty 1967 are still unable to guarantee legal certainty so that all parties carrying out commercial activities in space obey them; (2) the calculation of damage caused by commercial activities in space will result in liability that has been regulated in the Space Liability Convention 1972 that there are two legal principles governing the responsibility for compensation carried out by all parties in space, both state and private parties.

Application in Self-Adsorption Pd Nanoparticles with High Adhesion

Electroless plating (ELP) is widely used to metallize non-conductive substrates in printed circuit board industry. Due to the complexity of commercial palladium catalysts activation procedure and the high price of palladium, we synthesized a type of palladium catalyst with polyvinyl alcohol (PVA) as protector, formaldehyde (HCHO) as reducing agent. We used polyethylimine (PEI) to modify the surface of the substrate in advance.In this study, we developed a one-step catalyst by adding PEI into PVA-Pd. In addition to its stability, the catalyst has self-adsorption property. The process can be operated at low concentrations, which can effectively reduce the cost. Because of these characteristics, it can not only control the catalyst better than the commercial palladium catalyst but also simplify the process. The effect of self-adsorption was tested on Rogers RO3003 laminates. RO3003 high frequency laminates are ceramic-filled PTFE composites for use in printed circuit boards in commercial microwave and RF applications. The substrate has excellent characteristics such as stable dielectric constant over various temperatures and frequency and low coefficient of thermal expansion. Due to these properties, RO3003 has a great potential to be applied in 5G generation products. After activating, we used electroless copper plating to metallize the substrate.The study focused on the Cu/Pd ratio of the self-adsorption catalyst PEI+PVA-Pd to quantitatively analyze the adsorption capacity by ICP-OES, and the adhesion was analyzed by T-peel. The results indicates that the process is cost-effective, and the adhesion between substrate and copper foil is also higher. The copper layer by using self-adsorption catalyst will also have a better compactness and the surface will be pinhole-free. Therefore, this process can be successfully applied to electroless copper deposition with self-adsorption catalysts.