Burning Surface Research Articles

Is the Preoperative Wound Culture Necessary Before Skin Grafting Minor Burns? A Pilot Study in a Low Resource Setting Burn Service.

The most common cited cause of split-thickness skin graft failure is infection and due to the association between bacterial findings in wound beds an attempt to decrease the bacterial burden before skin-grafting evolved. Thus, preoperative microbiology swabs of the wound bed became routine at some institutions prior to grafting. This is not standard practice in the Pietermaritzburg Burn Service. Emphasis is instead placed on a strict protocol of intraoperative wound bed preparation to promote adequate graft take. This pilot study aims to evaluate whether preoperative wound swabs are appropriate. We performed a prospective observational study to determine if positive wound cultures were associated with graft failure. All patients with a burn surface area of less than 10%, where delayed grafting (later than 28 days from the time of burn injury) was performed, from March to December 2021 were analyzed. Patient demographics, days from burn to graft, %TBSA burn, %TBSA grafted, whether sharp debridement prior to grafting in the same procedure was performed or not, use of topical gentamicin intraoperatively, graft outcome (% graft loss), need for regraft, and organism grown were recorded into an excel spreadsheet for analysis. The sample included 52 patients. Of these, 17 (31.5%) were female. The median %TBSA grafted was 8% (IQR 4%-13%) and similar in both groups. The median days from burn to grafting were 35 days. Thirty-nine patients (75%) had graft Take and 13 (25%) had graft Failure. In the failed group, the median % graft failure was 50% (30%-70%). Of the group with successful graft take, 90% were noted to have had a positive wound culture prior to grafting. A positive wound culture was not found to be a risk factor for graft failure (P = .993). Despite the positive wound cultures graft take was more than 90% in 75% of grafts performed and only 2/52 patients required supplementary grafting. We believe that this demonstrates that our local protocol is reasonable in this setting and that waiting for negative wound swabs prior to grafting should not be a reason to delay grafting.

Amniotic membrane transplantation for ocular surface burns

Amniotic membrane transplantation for ocular surface burns

Experimental study on flow characteristics and burning behavior for fire of flammable gases leakage underwater

The occurrence of subsea pipeline leakage incidents has gradually increased with the rapid development of the offshore oil and gas industry. Research on the fire dynamics of flammable gases leakage underwater is very limited, particularly in understanding the coupling mechanism of flow and combustion on the water surface. This paper presents a systematical investigation on flow characteristics and burning behavior for fire of flammable gases leakage underwater. A series of laboratory-scale fire behavior experiments were conducted through a self-designed experimental platform, consisting of the leakage control module, water tank and measurement apparatus. It was revealed that the leakage flow rate and water depth would influence the flow characteristics and burning behavior significantly. Two different burning conditions were found for the flame burning above the water surface (FBWS), i.e., the stable and self-extinguishing (unstable) burning states. The dimensionless analysis is conducted for the burning conditions, where the critical criterion is developed to distinguish the stable and unstable burning states. The base diameter of stable FBWS is almost 1.6 times of the diameter of bubble plume on the water surface. The flame pulsation frequency and dimensionless flame height (the ratio of height to base diameter of flame) of the stable FBWS are different from thoes of liquid pool fires and gas diffusion fires. Consequently, a correlation between the Strouhal number and the Froude number is correlated. Finally, the correlation between the dimensionless flame height and the dimensionless heat release rate is proposed for the stable FBWS.

Diagnostic and Prognostic Value of Thrombocytopenia in Severe Burn Injuries.

Burn injuries are the most severe type of trauma, with complex biological consequences associated with high rates of morbidity and mortality. Prompt recognition and management of burn-related complications are imperative for improving the vital and functional prognosis of the patient. Changes in biological parameters can be essential determinants in the prognosis of the burned patient. Thrombocytopenia in critically ill patients is linked to an elevated risk of mortality. We sought to investigate the significance of thrombocytopenia in severely burned patients while considering the limited available data in the literature. A two-year retrospective study was conducted on 90 patients with severe burns admitted to our Burn Centre. Demographic data, burn lesion characteristics, and daily total blood counts, including platelet assessment, complications, and mortality, were recorded and analyzed. Patients with extensive burns in our study had a poor prognosis based on their Abbreviated Burn Severity Index score (ABSI), age, percentage of total body surface area (TBSA) burned, presence of third-degree burns, and inhalation injuries. Regardless of the moment, patients with thrombocytopenia in our study died significantly more frequently. Compared with the survivors, the platelet count was significantly lower at any given time in the non-survivors group. Significant statistical associations between thrombocytopenia and ABSI score, burn surface area, presence of third-degree burns, and inhalation injuries were identified at different timeframes post-burn injury. Sepsis was encountered in one-third of the patients. Thrombocytopenia was more frequent in patients with sepsis who did not survive compared to survivors and did not normalize until the time of death. Thrombocytopenia represents an early indicator of severe complications and outcome predictor in severely burned patients. It is correlated with recognized negative prognostic factors and also with sepsis occurrence. Future research efforts should focus on refining early detection parameters and interventions to improve the prognosis of burn patients.

Numerical investigation and experimental validation of aluminized propellant combustion under high pressures: Critical effects of heat feedback

Aluminum is a common metal fuel in propellants, but its effects on the burning rate and the underlying mechanism are still unclear. Numerical calculations and temperature measurement experiments were carried out within the pressure range of 0.1–9 MPa, and the effects of the pressure and the ammonium perchlorate (AP) particle size on the combustion characteristics of aluminized propellants were studied. First, based on a two-dimensional micro-scale combustion model of an AP/hydroxyl‑terminated polybutadiene (HTPB) propellant, by considering the “heat sink” effect of aluminum on the burning surface and the chemical reaction of aluminum in the gas phase, a numerical calculation model of heat flux coupled with the steady-state combustion of an aluminized propellant was established. The flame structure of an aluminized propellant obtained by this model conformed to the multi-flame structure and could correctly reflect the influence of the AP particle size and pressure on the burning rate and other combustion characteristics. Subsequently, the influence of radiation heat feedback was further introduced into the model, which greatly improved its accuracy in predicting the burning rate at low pressures of 1–3 MPa. More importantly, the temperature distributions of the propellants were measured using embedded tungsten–rhenium thermocouples, and the flame temperature was obtained by further processing the temperature measurement data according to the thermocouple response characteristics. The temperature measurement results showed that with the increase in the pressure and the decrease in the size of the AP particles, the temperature gradient increased significantly, the flame temperature increased slightly, and the burning rate of the propellant increased. By analyzing how the temperature gradient and the burning rate changed with pressure, it was found that the conduction heat feedback was important to determine the burning rate.

Determination of droplet size from wide-angle light scattering image data using convolutional neural networks

Wide-angle light scattering (WALS) offers the possibility of a highly temporally and spatially resolved measurement of droplets in spray-based methods for nanoparticle synthesis. The size of these droplets is a critical variable affecting the final properties of synthesized materials such as hetero-aggregates. However, conventional methods for determining droplet sizes from WALS image data are labor-intensive and may introduce biases, particularly when applied to complex systems like spray flame synthesis. To address these challenges, we introduce a fully automatic machine learning-based approach that employs convolutional neural networks (CNNs) in order to streamline the droplet sizing process. This CNN-based methodology offers further advantages: it requires few manual labels and can utilize transfer learning, making it a promising alternative to conventional methods, specifically with respect to efficiency. To evaluate the performance of our machine learning models, we consider WALS data from an ethanol spray flame process at various heights above burner surface, where the models are trained and cross-validated on a large dataset comprising nearly 35000 WALS images.

Clinical Efficacy of Autologous Simple Limbal Epithelial Transplantation for Stem Cell Deficiency in Ocular Surface Burn

Clinical Efficacy of Autologous Simple Limbal Epithelial Transplantation for Stem Cell Deficiency in Ocular Surface Burn

Regression transients modeling of solid rocket motor burning surfaces with physics-guided neural network

Monitoring the burning surface regression in ground static ignition tests is crucial for predicting the internal ballistic performance of solid rocket motors (SRMs). A previously proposed ultra-sparse computed tomography imaging method provides a possibility for real-time monitoring. However, sample shortages of SRMs highlights the need for monitoring accuracy, especially given the high cost associated with the design and development of SRM systems. Therefore, constructing datasets via regression simulations to compensate for SRM sample shortages is critical. To address this issue, we recommend adopting the level-set method to dynamically track the burning surface by solving partial differential equations (PDEs). The computational cost of numerical solution is prohibitive for scientific applications involving large-scale spatiotemporal domains. The physics-informed neural network (PINN) and neural operator have been used to accelerate the solution of PDE, showing satisfactory prediction performance and high computational efficiency. We designed a physics-guided network, named LS-PhyNet, that couples the potential physical mechanisms of burning surface regression into the deep learning framework. The proposed method is capable of encoding well-established traditional numerical discretization methods into the network architecture to leverage prior knowledge of underlying physics, thus providing the model with enhanced expressive power and interpretability. Experimental results prove that LS-PhyNet can better reproduce the burning surfaces obtained by numerical solution with only small data regimes, providing a new paradigm for real-time monitoring of burning surface regression transients during static ignition tests.

The Utilisation of INR to identify coagulopathy in burn patients.

Studies conflict on the significance of burn-induced coagulopathy. We posit that burn-induced coagulopathy is associated with injury severity in burns. Our purpose was to characterize coagulopathy profiles in burns and determine relationships between % total burn surface area (TBSA) burned and coagulopathy using the International Normalized Ratio (INR). Burned patients with INR values were identified in the TriNetX database and analyzed by %TBSA burned. Patients with history of transfusions, chronic hepatic failure, and those on anticoagulant medications were excluded. Interquartile ranges for INR in the burned study population were 1.2 (1.0-1.4). An INR of ≥ 1.5 was used to represent those with burn-induced coagulopathy as it fell outside the 3rd quartile. The population was stratified into subgroups using INR levels <1.5 or ≥1.5 on the day of injury. Data are average ± SD analyzed using chi-square; p < .05 was considered significant. There were 7,364 burned patients identified with INR <1.5, and 635 had INR ≥1.5. Comparing TBSA burned groups, burn-induced coagulopathy significantly increased in those with ≥20% TBSA; p = .048 at 20-29% TBSA, p = .0005 at 30-39% TBSA, and p < .0001 for 40% TBSA and above. Age played a significant factor with average age for those with burn-induced coagulopathy 59 ± 21.5 years and 46 ± 21.8 for those without (p < .0001). After matching for age, TBSA, and demographics, the risk of 28 day-mortality was higher in those with burn-induced coagulopathy compared to those without (risk difference 20.9%, p < .0001) and the odd ratio with 95% CI is 4.45 (3.399-5.825). Investigation of conditions associated with burn-induced coagulopathy showed the effect of heart diseases to be significant; 53% of patients with burn-induced coagulopathy had hypertension (p < .0001). Burn-induced coagulopathy increases with %TBSA burned. The information gained firmly reflects a link between %TBSA and burn-induced coagulopathy, which could be useful in prognosis and treatment decisions.

Determination of energy requirements after minor burns using indirect calorimetry: A descriptive cohort study.

Minor burns could be associated with moderate hypermetabolism. In this study, the primary outcome was measured energy expenditure (mEE) determined by indirect calorimetry in patients with minor burns. We also compared mEE with predictive values and actual energy intakes. Adults with minor burns exclusively treated on an outpatient basis were included. During the week following injury, a dietitian performed indirect calorimetry (Q-NRG in canopy mode), calculated the estimated energy expenditure (eEE) based on the Harris-Benedict (HB) and Henry formulas, and evaluated daily energy intakes using a food anamnesis. Forty-nine patients (59.2% male; median age: 35 [interquartile range: 29-46.5] years; body mass index [BMI]: 26.2 [22.3-29.6] kg/m2; burn surface area [BSA]: 1.5% [1%-2%]) were included 4 (2-6) days after injury. The mEE was 1863 (1568-2199) kcal or 25 (22.4-28.5) kcal/kg and 1838 (1686-2026) kcal or 26.1 (23.7-27.7) kcal/kg in patients who were respectively fasting for >10 h or not (P = 0.991 or P = 0.805). The total mEE was 104% (95%-116%) and 108% (99%-122%) of the total eEE using the HB and Henry formulas, respectively, with diet-induced thermogenesis and physical activity level. Hypermetabolism (ie, oxygen consumption at rest ≥3.5 ml/kg/min) was observed in 21/49 (42.9%) patients. Energy intakes corresponded to 71% (60%-86%) of the total mEE. Performing indirect calorimetry in adults with minor burns revealed that ≥40% of the tested adults presented a hypermetabolism and that their mEE was not covered by their energy intakes.

Final assessment of multifactor experiments of heat transfer in the underwater wet welding

The multifactorial nature and interconnection of phenomena occurring during welding, especially under water, are important for deepening knowledge in this area. An analysis of the research carried out and the solutions obtained in the field of underwater wet welding of low-carbon steels shows that in this area, adequate assessments of the effectiveness of various types of welding with comprehensive consideration of the interaction of various physical phenomena, significantly different in nature from each other, have not been obtained. Integrated approaches to the assessment and analysis of heat transfer coefficients from the side of the arc combustion surface and from the opposite side are proposed. For the first time, the potential values were calculated as a change in the values of heat transfer indicators for various welding conditions based on verified experimental data. The ultimate goal of the work is to calculate the cooling rates of the metal of the welded joint, which will subsequently make it possible to predict the mechanical properties of the weld metal and the likelihood of the formation of hardening structures.

Blast Eye Injury After Mobile Phone Battery Explosion: A Case Report

Introduction : Injuries from mobile phone blasts have been on the rise in recent years. Mobile phone blasts cause serious ocular morbidity. We report a rare case of blast eye injury after mobile phone battery explosion.&#x0D; Case Illustration : A 16 years old woman presented with burning sensation on both the eyes, following a smartphone battery blast. Immediately, after disconnecting the phone from the charger, the battery exploded and the phone blew apart. Her presenting visual acuity was 1/300 and 1.0 in right eye and left eye. Examination revealed broad corneal haziness on right eye, charred lashes, circumciliary congestion, and multiple soot particles embedded over the cornea, conjunctiva, and the lid margins. The eyes were washed with copious ringer lactate and the debris was carefully removed. Topical preservative free lubricants, broad-spectrum antibacterial agent, corticosteroid, and cycloplegic agent were prescribed along with systemic nonsteroidal anti-inflammatory drug. The healing of epithelial defects started on the next day and was complete by the 14th day.&#x0D; Discussion : We describe an ocular blast injury due to mobile phone explosion. The mechanism of injury from battery blast could be a combination of mechanical (battery pieces), thermal, and chemical injuries. The vision can be saved if the ocular surface burns are treated promptly and properly.&#x0D; Conclusion : Mobile blast injury is emerging as a new mode of ocular trauma. Knowing proper management is very important to achieve the best result.

A new fluorocarbon adhesive: Inhibiting agglomeration during combustion of propellant via efficient F–Al2O3 preignition reaction

AbstractInhibiting the agglomeration of molten aluminum particles packed in the binder network is a promising scheme to achieve efficient combustion of solid propellants. In this investigation, the hydroxyl‐terminated structured fluorinated alcohol compound (PFD) was introduced to modify the traditional polyethylene glycol/polytetrahydrofuran block copolymerization (HTPE) binder; that is, a unique fluorinated polyether (FTPE) binder was synthesized by embedding fluorinated organic segments into the HTPE binder via crosslinking curing. The FTPE was applied in aluminum‐based propellants for the first time. Due to the complete release of fluorinated organic active segments in the range of 300°C to 400°C, the burning rate of FTPE‐based propellant increased from 4.07 (0% PFD) to 6.36 mm/s (5% PFD), increased by 56.27% under 1 MPa. The reaction heat of FTPE propellants increased from 5.95 (0% PFD) to 7.18 MJ/kg (5% PFD) under 3.0 MPa, indicating that HTPE binder modified with PFD would be conducive to inhibiting the D90 of condensed combustion products (CCPs) dropped by 81.84% from 75.46 (0% PFD) to 13.71 μm (5% PFD) under 3.0 MPa, in consistent with the significant reduction of aluminum agglomerates observed on the quenched burning surface of the propellants. Those results demonstrated that a novel FTPE binder with PFD can release fluorinated organic active segments, which motivate preignition reaction with the alumina shell in the early stage of aluminum combustion, and then enhance the melting diffusion effect of aluminum to inhibit the agglomeration.

Experimental and numerical study of PMMA combustion in counterflow configuration

PMMA burning in counterflow has been studied experimentally and numerically. Thermal and chemical structure including concentrations of main species, i.e. ММА, O2, N2, CO2, CO and H2O, as well as an integral parameter (mass loss rate of a sample) were measured. The mathematical model is set in a coupled gas–solid formulation to resolve heat and mass transfer between gas-phase flame and thermally degrading solid combustible. Gas-phase combustion was modeled in the open-source Cantera software in a one-dimensional counterflow flame configuration. Governing equations of solid fuel was solved in an in-house code in two-dimensional formulation. Two chemical mechanisms of MMA oxidation (skeletal and detailed) were employed to resolve gas-phase combustion. Two sets of parameters of PMMA pyrolysis reaction were investigated. Gas phase temperature distribution was experimentally shown to be almost uniform in the direction parallel to the sample's burning surface in the area up to 4 mm from the sample's axis. The best agreement for macroscopic parameter, mass loss rate, was obtained by employing Lengelle pyrolysis kinetics, which is within 10 %. Total heat flux from gas-phase flame to the solid sample is about 23 kW/m2. Both gas-phase combustion mechanisms overpredict maximal temperature in flame by about 200 °C.

Experimental Research on Heat Transfer and Ignition Characteristics of Series Fault Arc Combustion in 220VAC Power System

ABSTRACT This paper studied the heat transfer and ignition characteristics of series fault arcs combustion in the 220VAC power system. Series fault arcs with seven currents (4-30A) were generated to investigate the outward heat transfer characteristics of arc combustion. The distance between the fault arc and the combustibles was changed in experiments to study ignition characteristics. Electrode temperature and arc near-domain temperature, ignition time, and temp-erature of the combustible surface were measured. The results show that the ambient air temperature rise (T-T 0) is inversely proportional to the radial distance from the fault arc (r), and there is a linear relationship between the temperature (T-T 0) and the current divided by the radial distance from the fault arc (I/r). As for the temperature of the electrode, the larger current causes a higher electrode temperature. A semi-infinite solid ignition model is used to deal with the ignition process of the combustibles. Experimental results show that there is a good linear relationship between the current (I 2) and the ignition time ( t ig − 1 / 2 ). This study quantitatively evaluates the hazards of arc combustion and is of great significance for explaining the ignition mechanism of an arc-type electrical fire.

Hybrid Rocket Engine Burnback Simulations Using Implicit Geometry Descriptions

The performance of hybrid rocket engines is significantly influenced by the fuel geometry. Burnback simulations, to determine the fuel surface and fluid volume, are therefore an important tool for preliminary design. This work presents a method for the simulation of spatially constant burn-ups on arbitrary geometries. An implicit surface definition by means of a signed distance function is used to represent the fluid volume and the fuel block on tetrahedral meshes. Two methods each are used to determine the fluid volume and the burning surface. The first method is based on a direct integration of the signed distance function with the Heaviside function or the Dirac delta distribution, respectively. The second method linearly interpolates the position of an isosurface and thus reconstructs the fuel surface. Both methods are compared and validated with analytical results of four example geometries. Both calculations of the fluid volume and the calculation of the surface content with the interpolation method are characterized as first-order methods. With practicable mesh resolutions of one million computational cells, errors below two percent can be achieved. With the interpolation method, numerical meshes can also be exported for any time points of the burn. Finally, the application of the program to the fuel geometry of the Viserion hybrid rocket engine is demonstrated.

Epidemiological and cost analysis of burned patients in Iran

IntroductionConsidering the financial support provided by insurance and the government for burn patients in Iran, and recognizing the substantial economic impact associated with their treatment, there is a pressing need to delve into the epidemiology of these patients and analyze the related costs. This study aims to explore the epidemiological aspects and hospitalization costs of burn patients specifically within the burn ward of Imam Reza 68-bed Hospital in Mashhad, a regional center of referral in the eastern part of the country. MethodsData had extracted from the electronic data collection system, which is used on a daily basis in the hospital. We included patients with a primary or secondary diagnosis of burns, code T20.0-T32.9 and T95 according to the International Classification of Diseases ICD-10. Ultimately, 1151 patients were included in the study. We analyzed 1151 burn cases in terms of patients’ age at the time of the event, gender, type of burn (Chemical, scalds, flame, electrical and contact burns), anatomical location of the burn (head and neck, upper limb, lower limb, multiple regions and part unspecified), burn etiology, burn degree (I, II, III), total burn surface area (%TBSA), Inpatient ward, expenditure ($), burn mortality rate and length of hospitalization. The age group was divided into seven groups by the 10 years intervals. Statistical analysis of the data was performed using SPSS-16 and Excel software. Results1151 patients were included in the study. High-risk groups are pediatric up to nine (0–9) years. According to age, we found that most cases were children, respectively, 25% (291) cases. Men accounted for 743 cases (65%), women for 408 (35%). Major causes of severe burn injury were flame burns (49%) and scalds (43%). Unspecified was the most common burn location (40%), followed by the multiple regions (23%) and upper limb (11%). In cases of head and neck burns, the financial burden on the patient is elevated compared to other types of burns due to increased expenses for medications, disposable medical instruments, and hoteling. The main items for the burned patients are hoteling (38% of total costs), surgeon (24%), medicine (16%), and medical consumables (6%). The per capita expenditure was $9,365 ± $8,100 in pediatrics and $11,179 ± $10,180 in adults Conclusions: Most cases of death were related to burn in multiple areas of the body and then trunk burn (30% and 19%, respectively) and no death was observed in patients with hand and wrist burn. Burns can be incredibly severe and life-threatening, especially when they affect multiple areas of the body, such as the trunk and any burn injury is still a serious matter. It's important to prioritize fire safety and take precautions to prevent such accidents from happening.

Assessment of health-related quality of life in patients with burns injuries during the COVID-19 epidemic: A critical topic for burn survivors

PurposeIt is well known that the coronavirus disease 19 (COVID-19) epidemic had an adverse effect on the health-related quality of life (HRQOL) of patients with disabilities, or neurological or chronic conditions. The aim of this study was to examine the possible factors affecting HRQOL in patients with burn injuries during COVID-19 epidemic. MethodsThe study included a total of 40 burns patients. The demographic and burn injury information of the patients were recorded. The active range of motion was measured with a goniometer. The HRQOL, community integration, scar tissue quality and anxiety level were evaluated using the Burn-Specific Health Scale (BSHS), the Community Integration Questionnaire Revised (CIQ-R), Patient and Observer Scar Assessment Scale, and the State-Trait Anxiety Inventory, respectively. ResultsThe history of COVID-19 infection, total burn surface area (TBSA), community integration level, work-related burns, the presence of trunk burn injury, the presence of face burn injury, and the presence of a major burn injury were determined to be significantly associated with the HRQOL of burns patients (p < 0.05). ConclusionThe history of COVID-19 infection, community integration level, and burn-related parameters (TBSA, localization, severity etc.) were found to be factors associated with the HRQOL during the epidemic. The history of COVID-19 and community integration level should be evaluated in addition to the burn injury parameters to improve the quality of life of burn survivors. It can be recommended that these clinical parameters should be considered when planning the treatment program during and after the epidemic.

Evaluation of Mixing Effect on Coupled Heat Release and Transfer Performance of a Novel Segregated Solid Rocket Motor

The effect of mixing on coupled heat release and transfer performance of a novel segregated solid motor is numerically evaluated with a transient two-dimensional combustion model. The results show that vortex structures are formed and evolved in the combustion chamber. Quantitative calculation of the mixing effect shows the inhomogeneous distribution of oxidant and fuel species. The well-mixing area is located in a narrow belt-like coupled combustion region near the burning surface of the propellant. Heat transfer coefficient decreases greatly due to lower combustion reaction rate and enlarged flow channel area. Heat transfer coefficients near the two ends of the propellant grain are higher than other parts due to the influence of vortex mixing. Raising the inlet mass flow rate leads to enhanced mixing and heat transfer, which results in a lower temperature and regression rate of the propellant with combustion time. Temperature and oxidation rates of H2 and CO are unevenly distributed in the boundary layer of coupled combustion. Increasing the mass flux of inlet oxidizer gas leads to a higher combustion heat release rate. Therefore, the gas-phase temperature increases significantly. The heat release rate reaches the maximum near the ends of the propellant grain, where vortex mixing strengthens the coupled combustion process in the motor.

The Use of Intraosseous Infusion in the Early Resuscitation of Patients With Extremely Severe Burns.

According to research, shock, the most common complication of extremely severe burns, is also the leading cause of mortality among patients with such burns. The case fatality rate reaches 83.45% when the total burn area exceeds 90%. The American Heart Association in 2020 recommended the intraosseous (IO) access after the peripheral access and prior to the central venous access when venous cannulation is either difficult or delayed. The use and experience with intraosseous infusion in extremely severe burns are still limited. We report efficacy and safety results from 19 burn patients treated with IO infusion between June 2020 and December 2022. In these patients, the mean injury time of burns was 1.55 ± 1.10 hours, the mean burn surface area was 86.24% ± 11.33%, the mean catheterization time was 49.68 ± 10.11 seconds, and the mean emergency retention time was 2.75 ± 1.74 hours, the mean actual fluid supplement amount was 5,533.68 ± 3,077.19 mL, the mean hourly urine volume of the patient was 93.31 ± 60.94 mL, the mean emergency detention time was 4.16 ± 2.97 hours, and the mean duration of hospitalization was 34.50 ± 25.38 days. The results demonstrated a clinically meaningful improvement and higher response rate vs peripheral venous cannulation and an acceptable safety profile in those patients.